RU2006127474A - Фармацевтическая композиция для стимуляции антиогенеза - Google Patents
Фармацевтическая композиция для стимуляции антиогенеза Download PDFInfo
- Publication number
- RU2006127474A RU2006127474A RU2006127474/15A RU2006127474A RU2006127474A RU 2006127474 A RU2006127474 A RU 2006127474A RU 2006127474/15 A RU2006127474/15 A RU 2006127474/15A RU 2006127474 A RU2006127474 A RU 2006127474A RU 2006127474 A RU2006127474 A RU 2006127474A
- Authority
- RU
- Russia
- Prior art keywords
- group
- pharmaceutical composition
- lower alkyl
- use according
- alkyl group
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Claims (4)
1. Применение соединения для получения фармацевтической композиции для стимуляция ангиогенеза, причем фармацевтическая композиция в качестве активного ингредиента содержит по меньшей мере одно соединение, выбранное из группы, состоящей из соединения пиперидина, представленного общей формулой (1), или его солей
где R представляет собой бензоильную группу, которая может содержать в качестве заместителей в фенильном кольце от 1 до 3 групп, выбранных из группы, состоящей из аминогруппы, которая может содержать низшую алканоильную группу, и низшей алкильной группы; R1 представляет собой атом водорода или низшую алкильную группу; и R2 представляет группу фенил-низший алкил.
2. Применение по п.1, где соединение пиперидина представляет собой 4-[N-метил-N-(2-фенилэтил)амино]-1-(3,5-диметил-4-пропиониламинобензоил)пиперидин.
3. Применение по п.1 или 2, где фармацевтическая композиция для стимуляции ангиогенеза является профилактическим или лечебным лекарственным средством при заболеваниях с недостаточным развитием и регенерацией кровеносных сосудов и различных заболеваниях, вызванных ишемией.
4. Применение по п.3, где заболевания с недостаточным развитием и регенерацией кровеносных сосудов и различные заболевания, вызванные ишемией, представляют собой инфаркт миокарда, стенокардию, инфаркт головного мозга, сенильную деменцию и повреждения различных органов, сопровождаемые сахарным диабетом.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004020859 | 2004-01-29 | ||
| JP2004-020859 | 2004-01-29 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2006127474A true RU2006127474A (ru) | 2008-02-10 |
| RU2354375C2 RU2354375C2 (ru) | 2009-05-10 |
Family
ID=34823768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2006127474/15A RU2354375C2 (ru) | 2004-01-29 | 2005-01-26 | Фармацевтическая композиция для стимуляции ангиогенеза |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US8445516B2 (ru) |
| EP (1) | EP1708705B1 (ru) |
| JP (1) | JP2012006973A (ru) |
| KR (1) | KR100868470B1 (ru) |
| CN (1) | CN100473383C (ru) |
| AR (1) | AR047464A1 (ru) |
| AT (1) | ATE422888T1 (ru) |
| AU (1) | AU2005207746B2 (ru) |
| BR (1) | BRPI0506578A (ru) |
| CA (1) | CA2553918C (ru) |
| CY (1) | CY1108933T1 (ru) |
| DE (1) | DE602005012799D1 (ru) |
| DK (1) | DK1708705T3 (ru) |
| ES (1) | ES2321310T3 (ru) |
| HK (1) | HK1095755A1 (ru) |
| MY (1) | MY142362A (ru) |
| PL (1) | PL1708705T3 (ru) |
| PT (1) | PT1708705E (ru) |
| RU (1) | RU2354375C2 (ru) |
| SI (1) | SI1708705T1 (ru) |
| TW (1) | TWI369986B (ru) |
| WO (1) | WO2005072734A1 (ru) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2679586B1 (en) | 2007-04-27 | 2016-02-10 | Daiichi Sankyo Company, Limited | Nitrogen-containing six-membered aromatic ring derivatives and pharmaceutical products containing the same |
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-
2005
- 2005-01-11 MY MYPI20050100A patent/MY142362A/en unknown
- 2005-01-19 TW TW094101567A patent/TWI369986B/zh not_active IP Right Cessation
- 2005-01-26 AR ARP050100267A patent/AR047464A1/es unknown
- 2005-01-26 ES ES05704342T patent/ES2321310T3/es active Active
- 2005-01-26 CA CA2553918A patent/CA2553918C/en not_active Expired - Fee Related
- 2005-01-26 PL PL05704342T patent/PL1708705T3/pl unknown
- 2005-01-26 RU RU2006127474/15A patent/RU2354375C2/ru not_active IP Right Cessation
- 2005-01-26 BR BRPI0506578-0A patent/BRPI0506578A/pt not_active IP Right Cessation
- 2005-01-26 US US10/587,045 patent/US8445516B2/en not_active Expired - Fee Related
- 2005-01-26 AT AT05704342T patent/ATE422888T1/de active
- 2005-01-26 WO PCT/JP2005/001444 patent/WO2005072734A1/en not_active Application Discontinuation
- 2005-01-26 PT PT05704342T patent/PT1708705E/pt unknown
- 2005-01-26 EP EP05704342A patent/EP1708705B1/en not_active Not-in-force
- 2005-01-26 AU AU2005207746A patent/AU2005207746B2/en not_active Ceased
- 2005-01-26 CN CNB2005800016511A patent/CN100473383C/zh not_active Expired - Fee Related
- 2005-01-26 SI SI200530643T patent/SI1708705T1/sl unknown
- 2005-01-26 DE DE602005012799T patent/DE602005012799D1/de active Active
- 2005-01-26 DK DK05704342T patent/DK1708705T3/da active
- 2005-01-26 KR KR1020067014350A patent/KR100868470B1/ko not_active IP Right Cessation
-
2007
- 2007-03-23 HK HK07103158.5A patent/HK1095755A1/xx not_active IP Right Cessation
-
2009
- 2009-03-26 CY CY20091100358T patent/CY1108933T1/el unknown
-
2011
- 2011-09-20 JP JP2011204957A patent/JP2012006973A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ATE422888T1 (de) | 2009-03-15 |
| US20090187025A1 (en) | 2009-07-23 |
| KR20060127053A (ko) | 2006-12-11 |
| TW200526211A (en) | 2005-08-16 |
| TWI369986B (en) | 2012-08-11 |
| WO2005072734A1 (en) | 2005-08-11 |
| EP1708705A1 (en) | 2006-10-11 |
| DE602005012799D1 (de) | 2009-04-02 |
| AU2005207746A1 (en) | 2005-08-11 |
| RU2354375C2 (ru) | 2009-05-10 |
| PT1708705E (pt) | 2009-04-14 |
| US8445516B2 (en) | 2013-05-21 |
| PL1708705T3 (pl) | 2009-07-31 |
| BRPI0506578A (pt) | 2007-04-10 |
| KR100868470B1 (ko) | 2008-11-12 |
| DK1708705T3 (da) | 2009-05-11 |
| SI1708705T1 (sl) | 2009-06-30 |
| CN1905877A (zh) | 2007-01-31 |
| CA2553918C (en) | 2011-06-21 |
| AR047464A1 (es) | 2006-01-18 |
| MY142362A (en) | 2010-11-30 |
| ES2321310T3 (es) | 2009-06-04 |
| CA2553918A1 (en) | 2005-08-11 |
| CY1108933T1 (el) | 2014-07-02 |
| EP1708705B1 (en) | 2009-02-18 |
| JP2012006973A (ja) | 2012-01-12 |
| CN100473383C (zh) | 2009-04-01 |
| HK1095755A1 (en) | 2007-05-18 |
| AU2005207746B2 (en) | 2007-08-16 |
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