RU2005109554A - Раствор для применения в области ногтей и околоногтевого пространства - Google Patents
Раствор для применения в области ногтей и околоногтевого пространства Download PDFInfo
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- RU2005109554A RU2005109554A RU2005109554/15A RU2005109554A RU2005109554A RU 2005109554 A RU2005109554 A RU 2005109554A RU 2005109554/15 A RU2005109554/15 A RU 2005109554/15A RU 2005109554 A RU2005109554 A RU 2005109554A RU 2005109554 A RU2005109554 A RU 2005109554A
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- nails
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- urea
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- 239000000203 mixture Substances 0.000 claims abstract 10
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims abstract 8
- 239000004202 carbamide Substances 0.000 claims abstract 8
- 239000013543 active substance Substances 0.000 claims abstract 5
- XXJWXESWEXIICW-UHFFFAOYSA-N diethylene glycol monoethyl ether Chemical compound CCOCCOCCO XXJWXESWEXIICW-UHFFFAOYSA-N 0.000 claims abstract 5
- 229940121375 antifungal agent Drugs 0.000 claims abstract 3
- 239000003795 chemical substances by application Substances 0.000 claims abstract 3
- 230000007170 pathology Effects 0.000 claims abstract 3
- 208000010195 Onychomycosis Diseases 0.000 claims abstract 2
- 239000002537 cosmetic Substances 0.000 claims abstract 2
- 230000002538 fungal effect Effects 0.000 claims abstract 2
- 201000005882 tinea unguium Diseases 0.000 claims abstract 2
- 239000002253 acid Substances 0.000 claims 4
- 239000003961 penetration enhancing agent Substances 0.000 claims 3
- 230000035699 permeability Effects 0.000 claims 3
- 150000007933 aliphatic carboxylic acids Chemical class 0.000 claims 2
- 239000003429 antifungal agent Substances 0.000 claims 2
- 239000006184 cosolvent Substances 0.000 claims 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 2
- 239000003960 organic solvent Substances 0.000 claims 2
- 239000004014 plasticizer Substances 0.000 claims 2
- MQHLMHIZUIDKOO-OKZBNKHCSA-N (2R,6S)-2,6-dimethyl-4-[(2S)-2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine Chemical group C1=CC(C(C)(C)CC)=CC=C1C[C@H](C)CN1C[C@@H](C)O[C@@H](C)C1 MQHLMHIZUIDKOO-OKZBNKHCSA-N 0.000 claims 1
- 229960003204 amorolfine Drugs 0.000 claims 1
- 230000002708 enhancing effect Effects 0.000 claims 1
- 235000014655 lactic acid Nutrition 0.000 claims 1
- 239000004310 lactic acid Substances 0.000 claims 1
- 229940127554 medical product Drugs 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 230000000149 penetrating effect Effects 0.000 abstract 2
- 230000000843 anti-fungal effect Effects 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q3/00—Manicure or pedicure preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q3/00—Manicure or pedicure preparations
- A61Q3/02—Nail coatings
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Birds (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
Claims (14)
1. Применение смеси агентов, улучшающих проницаемость, которые действуют синергично, выбранных из мочевины, кислоты и этоксидигликоля, для получения раствора для нанесения в области ногтей и околоногтевого пространства для фармацевтического или косметического использования.
2. Применение по п.1, отличающееся тем, что раствор представляет собой пленкообразующий раствор или лак для ногтей.
3. Применение по п.1, отличающееся тем, что используют смесь агентов, улучшающих проницаемость, включающую, по меньшей мере, мочевину и этоксидигликоль.
4. Применение по п.2, отличающееся тем, что используют смесь агентов, улучшающих проницаемость, включающую, по меньшей мере, мочевину и этоксидигликоль.
5. Применение по любому из пп.1-4, отличающееся тем, что используют смесь агентов, улучшающих проницаемость, включающую, по меньшей мере, мочевину и кислоту.
6. Раствор для нанесения в области ногтей и околоногтевого пространства, включающий смесь агентов, улучшающих проницаемость, включающую, по меньшей мере, мочевину и этоксидигликоль.
7. Раствор по п.6, отличающийся тем, что он дополнительно включает
а) по меньшей мере, один активный агент,
b) смесь органический растворитель/сорастворитель,
с) и, необязательно, пластификатор.
8. Раствор для нанесения в области ногтей и околоногтевого пространства, включающий смесь агентов, улучшающих проницаемость, включающую, по меньшей мере, мочевину и кислоту, отличающийся тем, что он находится в виде неводного пленкообразующего раствора и тем, что он содержит количество мочевины, составляющее менее 15% мас. по отношению к общей массе нелетучего компонента композиции.
9. Раствор для нанесения в области ногтей и околоногтевого пространства по п.8, отличающийся тем, что кислота представляет собой алифатическую карбоновую кислоту.
10. Раствор для нанесения в области ногтей и околоногтевого пространства по п.9, отличающийся тем, что алифатическая карбоновая кислота представляет собой молочную кислоту.
11. Раствор для нанесения в области ногтей и околоногтевого пространства по любому из пп.8-10, отличающийся тем, что он дополнительно включает
а) по меньшей мере, один активный агент,
b) смесь органический растворитель/сорастворитель,
с) и, необязательно, пластификатор.
12. Раствор для нанесения в области ногтей и околоногтевого пространства по п.11, отличающийся тем, что активный агент представляет собой противогрибковое средство.
13. Раствор для нанесения в области ногтей и околоногтевого пространства по п.12, отличающийся тем, что противогрибковое средство выбирают из аморолфина или одной из его солей.
14. Применение раствора для нанесения в области ногтей и околоногтевого пространства по любому из предыдущих пунктов для получения медицинского продукта, предназначенного для лечения грибковых патологий, таких как онихомикоз.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0211023 | 2002-09-05 | ||
| FR0211023A FR2844197B1 (fr) | 2002-09-05 | 2002-09-05 | Solution pour application ungueale et peri-ungeale |
| US41134902P | 2002-09-18 | 2002-09-18 | |
| US60/411,349 | 2002-09-18 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2005109554A true RU2005109554A (ru) | 2005-08-20 |
| RU2329063C2 RU2329063C2 (ru) | 2008-07-20 |
Family
ID=31979940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2005109554/15A RU2329063C2 (ru) | 2002-09-05 | 2003-09-01 | Раствор для применения в области ногтей и околоногтевого пространства |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US7588753B2 (ru) |
| EP (1) | EP1545619B1 (ru) |
| JP (1) | JP2005538156A (ru) |
| KR (1) | KR20050042488A (ru) |
| AT (1) | ATE384534T1 (ru) |
| AU (1) | AU2003270273B2 (ru) |
| BR (1) | BR0313343A (ru) |
| CA (1) | CA2492976C (ru) |
| CY (1) | CY1107925T1 (ru) |
| DE (1) | DE60318867T2 (ru) |
| DK (1) | DK1545619T3 (ru) |
| ES (1) | ES2301814T3 (ru) |
| HK (1) | HK1085390A1 (ru) |
| MX (1) | MXPA05002065A (ru) |
| PL (1) | PL373235A1 (ru) |
| PT (1) | PT1545619E (ru) |
| RU (1) | RU2329063C2 (ru) |
| WO (1) | WO2004021968A2 (ru) |
| ZA (1) | ZA200501715B (ru) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8257688B2 (en) * | 2000-03-27 | 2012-09-04 | Taro Pharmaceuticals Industries | Controlled delivery system of antifungal and keratolytic agents for local treatment of fungal infections of the nail and surrounding tissues |
| US7820186B2 (en) * | 2001-12-21 | 2010-10-26 | Galderma Research & Development | Gel composition for once-daily treatment of common acne comprising a combination of benzoyl peroxide and adapalene and/or adapalene salt |
| PT1545619E (pt) | 2002-09-05 | 2008-02-28 | Galderma Sa | Solução destinada a uma aplicação sobre as unhas |
| JP4842800B2 (ja) * | 2003-02-21 | 2011-12-21 | ザ・ガヴァメント・オブ・ザ・ユナイテッド・ステイツ・オブ・アメリカ，アズ・リプレゼンテッド・バイ・ザ・セクレタリー・オブ・ザ・デパートメント・オブ・ヘルス・アンド・ヒューマン・サーヴィシーズ | サフィンゴールの医薬組成物およびその使用方法 |
| FR2867978B1 (fr) * | 2004-03-29 | 2009-02-20 | Galderma Res & Dev | Patch d'amorolfine pour le traitement de l'onychomicose |
| JP4595534B2 (ja) * | 2004-12-27 | 2010-12-08 | アサヌマ コーポレーション株式会社 | 爪化粧料 |
| FR2884419B1 (fr) * | 2005-04-19 | 2007-06-22 | Galderma Sa | Composition de type solution filmogene comprenant de la vitamine d ou un de ses derives et un corticosteroide, et son utilisation en dermatologie |
| FR2892023B1 (fr) * | 2005-10-14 | 2009-09-25 | Galderma Sa | Composition pharmaceutique a base d'amorolfine et d'agent filmogene hydrosoluble pour application ungueale et peri-ungueale |
| EP1945033A1 (en) * | 2005-10-24 | 2008-07-23 | Staval Pharma, Ltd. | Method for treating/controlling/killing fungi and bacteria |
| US20080220103A1 (en) * | 2005-10-24 | 2008-09-11 | Jay Birnbaum | Method for treating/controlling/killing fungi and bacteria on living animals |
| CA2645070C (en) | 2006-03-08 | 2014-02-04 | Nihon Nohyaku Co., Ltd. | Pharmaceutical composition for external use |
| EP2025337B1 (en) * | 2006-03-08 | 2014-09-10 | Nihon Nohyaku Co., Ltd. | Pharmaceutical composition for external use |
| RU2415669C2 (ru) | 2006-03-08 | 2011-04-10 | Нихон Нохияку Ко., Лтд. | Фармацевтическая композиция для наружного применения |
| CA2653782A1 (en) * | 2006-06-14 | 2007-12-21 | Dr. Reddy's Laboratories Limited | Topical compositions |
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| US20080175919A1 (en) * | 2007-01-22 | 2008-07-24 | Fatemeh Mohammadi | Urea Compositions With Cooling Effect |
| CN101686958B (zh) | 2007-04-20 | 2017-02-08 | 瑞士商拜欧伊果公司 | 治疗指甲疾病的局部杀真菌药物 |
| JP5453093B2 (ja) | 2007-09-05 | 2014-03-26 | 株式会社ポーラファルマ | 抗真菌医薬組成物 |
| CN101808637B (zh) | 2007-09-05 | 2013-07-24 | 宝丽制药股份有限公司 | 医药组合物 |
| KR20100075476A (ko) | 2007-09-05 | 2010-07-02 | 가부시키가이샤 폴라 파마 | 항진균 조성물 |
| US20090175810A1 (en) | 2008-01-03 | 2009-07-09 | Gareth Winckle | Compositions and methods for treating diseases of the nail |
| AU2009290915B2 (en) * | 2008-09-10 | 2014-09-11 | Novartis Ag | Compositions for percutaneous administration |
| FR2937250B1 (fr) * | 2008-10-21 | 2013-05-10 | Fabre Pierre Dermo Cosmetique | Solution filmogene a base d'uree pour le traitement du psorasis de l'ongle |
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| NL2003786C2 (en) * | 2009-11-11 | 2010-07-30 | Medner B V | COMPOSITION FOR TOPICAL APPLICATION, USES THEREOF, APPLICATOR DEVICE AND KIT OF PARTS. |
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| KR101647545B1 (ko) | 2011-02-11 | 2016-08-10 | 모베르그 파르마 아베 | 신규 항진균 조성물 |
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-
2003
- 2003-09-01 PT PT03750635T patent/PT1545619E/pt unknown
- 2003-09-01 JP JP2004533512A patent/JP2005538156A/ja active Pending
- 2003-09-01 WO PCT/EP2003/010694 patent/WO2004021968A2/en active IP Right Grant
- 2003-09-01 AU AU2003270273A patent/AU2003270273B2/en not_active Ceased
- 2003-09-01 MX MXPA05002065A patent/MXPA05002065A/es active IP Right Grant
- 2003-09-01 CA CA2492976A patent/CA2492976C/en not_active Expired - Fee Related
- 2003-09-01 KR KR1020057003664A patent/KR20050042488A/ko not_active Application Discontinuation
- 2003-09-01 BR BR0313343-5A patent/BR0313343A/pt not_active IP Right Cessation
- 2003-09-01 EP EP03750635A patent/EP1545619B1/en not_active Expired - Lifetime
- 2003-09-01 DE DE60318867T patent/DE60318867T2/de not_active Expired - Lifetime
- 2003-09-01 PL PL03373235A patent/PL373235A1/xx not_active Application Discontinuation
- 2003-09-01 RU RU2005109554/15A patent/RU2329063C2/ru not_active IP Right Cessation
- 2003-09-01 ES ES03750635T patent/ES2301814T3/es not_active Expired - Lifetime
- 2003-09-01 DK DK03750635T patent/DK1545619T3/da active
- 2003-09-01 AT AT03750635T patent/ATE384534T1/de active
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2005
- 2005-01-25 US US11/041,288 patent/US7588753B2/en not_active Expired - Fee Related
- 2005-02-28 ZA ZA2005/01715A patent/ZA200501715B/en unknown
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- 2006-05-11 HK HK06105478.4A patent/HK1085390A1/xx not_active IP Right Cessation
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Also Published As
| Publication number | Publication date |
|---|---|
| EP1545619B1 (en) | 2008-01-23 |
| MXPA05002065A (es) | 2005-06-08 |
| ES2301814T3 (es) | 2008-07-01 |
| PT1545619E (pt) | 2008-02-28 |
| AU2003270273B2 (en) | 2009-03-19 |
| CY1107925T1 (el) | 2013-09-04 |
| ATE384534T1 (de) | 2008-02-15 |
| CA2492976C (en) | 2011-11-01 |
| DK1545619T3 (da) | 2008-05-26 |
| ZA200501715B (en) | 2005-11-30 |
| KR20050042488A (ko) | 2005-05-09 |
| DE60318867D1 (de) | 2008-03-13 |
| PL373235A1 (en) | 2005-08-22 |
| US7588753B2 (en) | 2009-09-15 |
| AU2003270273A1 (en) | 2004-03-29 |
| WO2004021968A3 (en) | 2004-05-27 |
| HK1085390A1 (en) | 2006-08-25 |
| CA2492976A1 (en) | 2004-03-18 |
| JP2005538156A (ja) | 2005-12-15 |
| BR0313343A (pt) | 2005-07-12 |
| DE60318867T2 (de) | 2009-01-15 |
| WO2004021968A2 (en) | 2004-03-18 |
| RU2329063C2 (ru) | 2008-07-20 |
| US20050181999A1 (en) | 2005-08-18 |
| EP1545619A2 (en) | 2005-06-29 |
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