RS65839B1 - Crf1 receptor antagonisti za tretman kongenitalne adrenalne hiperplazije - Google Patents
Crf1 receptor antagonisti za tretman kongenitalne adrenalne hiperplazijeInfo
- Publication number
- RS65839B1 RS65839B1 RS20240910A RSP20240910A RS65839B1 RS 65839 B1 RS65839 B1 RS 65839B1 RS 20240910 A RS20240910 A RS 20240910A RS P20240910 A RSP20240910 A RS P20240910A RS 65839 B1 RS65839 B1 RS 65839B1
- Authority
- RS
- Serbia
- Prior art keywords
- receptor antagonist
- crf1 receptor
- glucocorticoid
- use according
- patient
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461929941P | 2014-01-21 | 2014-01-21 | |
| US201461981033P | 2014-04-17 | 2014-04-17 | |
| US201462069155P | 2014-10-27 | 2014-10-27 | |
| EP15702917.4A EP3096756B1 (en) | 2014-01-21 | 2015-01-21 | Crf1 receptor antagonists for the treatment of congenital adrenal hyperplasia |
| PCT/US2015/012315 WO2015112642A1 (en) | 2014-01-21 | 2015-01-21 | Crf1 receptor antagonists for the treatment of congenital adrenal hyperplasia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RS65839B1 true RS65839B1 (sr) | 2024-09-30 |
Family
ID=52450623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RS20240910A RS65839B1 (sr) | 2014-01-21 | 2015-01-21 | Crf1 receptor antagonisti za tretman kongenitalne adrenalne hiperplazije |
Country Status (24)
| Country | Link |
|---|---|
| US (5) | US20170020877A1 (enExample) |
| EP (2) | EP4450070A1 (enExample) |
| JP (5) | JP6585625B2 (enExample) |
| KR (2) | KR20210064407A (enExample) |
| CN (2) | CN106102740A (enExample) |
| AU (4) | AU2015209452C1 (enExample) |
| BR (1) | BR112016016975B1 (enExample) |
| CA (2) | CA2936974A1 (enExample) |
| DK (1) | DK3096756T3 (enExample) |
| ES (1) | ES2984706T3 (enExample) |
| FI (1) | FI3096756T3 (enExample) |
| HR (1) | HRP20241046T1 (enExample) |
| HU (1) | HUE068315T2 (enExample) |
| IL (5) | IL296683B2 (enExample) |
| LT (1) | LT3096756T (enExample) |
| MX (3) | MX389004B (enExample) |
| NZ (1) | NZ722122A (enExample) |
| PL (1) | PL3096756T3 (enExample) |
| PT (1) | PT3096756T (enExample) |
| RS (1) | RS65839B1 (enExample) |
| RU (1) | RU2718918C2 (enExample) |
| SI (1) | SI3096756T1 (enExample) |
| SM (1) | SMT202400361T1 (enExample) |
| WO (1) | WO2015112642A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210064407A (ko) | 2014-01-21 | 2021-06-02 | 뉴로크린 바이오사이언시즈 인코퍼레이티드 | 선천성 부신 과형성 치료를 위한 ｃｒｆ1 수용체 길항제 |
| CA3265373A1 (en) | 2014-02-20 | 2025-10-30 | H. Lundbeck A/S | Anti-acth antibodies and use thereof |
| EP3510029B1 (en) | 2016-09-07 | 2025-11-05 | The Regents of The University of California | Allosteric corticotropin-releasing factor receptor 1 (crfr1) antagonists that decrease p-tau and improve cognition |
| BR112020002967A2 (pt) | 2017-08-14 | 2020-08-11 | Spruce Biosciences, Inc. | antagonistas de receptor de fator de liberação de corticotropina |
| MX2020011344A (es) * | 2018-04-27 | 2021-02-09 | Spruce Biosciences Inc | Métodos para tratar tumores en reposo suprarrenales testiculares y de ovarios. |
| JP7532328B2 (ja) * | 2018-12-07 | 2024-08-13 | ニューロクライン バイオサイエンシーズ，インコーポレイテッド | 先天性副腎過形成を処置するためのｃｒｆ１受容体アンタゴニスト、その医薬製剤および固体形態 |
| PL3984523T3 (pl) * | 2018-12-07 | 2026-02-02 | Neurocrine Biosciences, Inc. | Antagonista receptora crf1, jego formulacje farmaceutyczne i postacie stałe do leczenia wrodzonego przerostu nadnerczy |
| KR20220052927A (ko) | 2019-07-19 | 2022-04-28 | 스프루스 바이오사이언시스 인코포레이티드 | 선천성 부신 증식증의 치료 방법 |
| US12383536B2 (en) | 2019-09-27 | 2025-08-12 | Neurocrine Biosciences, Inc. | CRF receptor antagonists and methods of use |
| ES3039926T3 (en) | 2019-12-04 | 2025-10-27 | Neurocrine Biosciences Inc | Crf receptor antagonists and methods of use |
| CA3181084A1 (en) * | 2020-06-10 | 2021-12-16 | Robert H. FARBER | Crf1 receptor antagonist for the treatment of congenital adrenal hyperplasia |
| JP2023537598A (ja) | 2020-08-12 | 2023-09-04 | スプルース バイオサイエンシーズ，インク． | 多嚢胞性卵巣症候群を処置するための方法および組成物 |
| MD20210019A2 (ro) | 2021-04-12 | 2022-10-31 | Максим МАСЮТИН | Metodă de tratament a hiperplaziei suprarenale congenitale, cauzate de deficit de 21-hidroxilază cu debut tardiv prin regimul de glucocorticoizi adaptat individual |
| US11708372B2 (en) | 2021-11-19 | 2023-07-25 | Spruce Biosciences, Inc. | Crystalline composition of tildacerfont and methods of use and preparation thereof |
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| KR20210064407A (ko) | 2014-01-21 | 2021-06-02 | 뉴로크린 바이오사이언시즈 인코퍼레이티드 | 선천성 부신 과형성 치료를 위한 ｃｒｆ1 수용체 길항제 |
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| BR112020002967A2 (pt) | 2017-08-14 | 2020-08-11 | Spruce Biosciences, Inc. | antagonistas de receptor de fator de liberação de corticotropina |
| TWI803504B (zh) | 2017-08-14 | 2023-06-01 | 美商雲杉生物科技股份有限公司 | 促皮質素釋放因子受體拮抗劑 |
| MX2020011344A (es) * | 2018-04-27 | 2021-02-09 | Spruce Biosciences Inc | Métodos para tratar tumores en reposo suprarrenales testiculares y de ovarios. |
| PL3984523T3 (pl) | 2018-12-07 | 2026-02-02 | Neurocrine Biosciences, Inc. | Antagonista receptora crf1, jego formulacje farmaceutyczne i postacie stałe do leczenia wrodzonego przerostu nadnerczy |
| KR20220052927A (ko) | 2019-07-19 | 2022-04-28 | 스프루스 바이오사이언시스 인코포레이티드 | 선천성 부신 증식증의 치료 방법 |
| US12383536B2 (en) | 2019-09-27 | 2025-08-12 | Neurocrine Biosciences, Inc. | CRF receptor antagonists and methods of use |
| ES3039926T3 (en) | 2019-12-04 | 2025-10-27 | Neurocrine Biosciences Inc | Crf receptor antagonists and methods of use |
| CA3181084A1 (en) | 2020-06-10 | 2021-12-16 | Robert H. FARBER | Crf1 receptor antagonist for the treatment of congenital adrenal hyperplasia |
| US20240024330A1 (en) | 2020-08-26 | 2024-01-25 | Neurocrine Biosciences, Inc. | Crf receptor antagonists and methods of use |
-
2015
- 2015-01-21 KR KR1020217015795A patent/KR20210064407A/ko not_active Ceased
- 2015-01-21 US US15/113,362 patent/US20170020877A1/en not_active Abandoned
- 2015-01-21 LT LTEPPCT/US2015/012315T patent/LT3096756T/lt unknown
- 2015-01-21 JP JP2016565135A patent/JP6585625B2/ja active Active
- 2015-01-21 BR BR112016016975-1A patent/BR112016016975B1/pt active IP Right Grant
- 2015-01-21 FI FIEP15702917.4T patent/FI3096756T3/fi active
- 2015-01-21 WO PCT/US2015/012315 patent/WO2015112642A1/en not_active Ceased
- 2015-01-21 HR HRP20241046TT patent/HRP20241046T1/hr unknown
- 2015-01-21 PT PT157029174T patent/PT3096756T/pt unknown
- 2015-01-21 MX MX2016009499A patent/MX389004B/es unknown
- 2015-01-21 RS RS20240910A patent/RS65839B1/sr unknown
- 2015-01-21 ES ES15702917T patent/ES2984706T3/es active Active
- 2015-01-21 HU HUE15702917A patent/HUE068315T2/hu unknown
- 2015-01-21 EP EP24174933.2A patent/EP4450070A1/en active Pending
- 2015-01-21 CN CN201580005270.4A patent/CN106102740A/zh active Pending
- 2015-01-21 CA CA2936974A patent/CA2936974A1/en active Pending
- 2015-01-21 SI SI201532025T patent/SI3096756T1/sl unknown
- 2015-01-21 PL PL15702917.4T patent/PL3096756T3/pl unknown
- 2015-01-21 KR KR1020167022375A patent/KR102258522B1/ko active Active
- 2015-01-21 RU RU2016133972A patent/RU2718918C2/ru active
- 2015-01-21 CA CA3155599A patent/CA3155599A1/en active Pending
- 2015-01-21 DK DK15702917.4T patent/DK3096756T3/da active
- 2015-01-21 IL IL296683A patent/IL296683B2/en unknown
- 2015-01-21 AU AU2015209452A patent/AU2015209452C1/en active Active
- 2015-01-21 IL IL317035A patent/IL317035A/en unknown
- 2015-01-21 IL IL304134A patent/IL304134B2/en unknown
- 2015-01-21 NZ NZ722122A patent/NZ722122A/en unknown
- 2015-01-21 EP EP15702917.4A patent/EP3096756B1/en active Active
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2016
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2018
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2019
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2020
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2023
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