PL3096756T3 - Antagonisty receptora CRF1 do leczenia wrodzonego przerostu nadnerczy - Google Patents

Antagonisty receptora CRF1 do leczenia wrodzonego przerostu nadnerczy

Info

Publication number
PL3096756T3
PL3096756T3 PL15702917.4T PL15702917T PL3096756T3 PL 3096756 T3 PL3096756 T3 PL 3096756T3 PL 15702917 T PL15702917 T PL 15702917T PL 3096756 T3 PL3096756 T3 PL 3096756T3
Authority
PL
Poland
Prior art keywords
treatment
receptor antagonists
adrenal hyperplasia
congenital adrenal
crf1 receptor
Prior art date
Application number
PL15702917.4T
Other languages
English (en)
Inventor
Dimitri E. Grigoriadis
Original Assignee
Neurocrine Biosciences, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52450623&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3096756(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Neurocrine Biosciences, Inc. filed Critical Neurocrine Biosciences, Inc.
Publication of PL3096756T3 publication Critical patent/PL3096756T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245Oxadiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL15702917.4T 2014-01-21 2015-01-21 Antagonisty receptora CRF1 do leczenia wrodzonego przerostu nadnerczy PL3096756T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201461929941P 2014-01-21 2014-01-21
US201461981033P 2014-04-17 2014-04-17
US201462069155P 2014-10-27 2014-10-27
PCT/US2015/012315 WO2015112642A1 (en) 2014-01-21 2015-01-21 Crf1 receptor antagonists for the treatment of congenital adrenal hyperplasia

Publications (1)

Publication Number Publication Date
PL3096756T3 true PL3096756T3 (pl) 2024-10-28

Family

ID=52450623

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15702917.4T PL3096756T3 (pl) 2014-01-21 2015-01-21 Antagonisty receptora CRF1 do leczenia wrodzonego przerostu nadnerczy

Country Status (24)

Country Link
US (5) US20170020877A1 (pl)
EP (2) EP4450070A1 (pl)
JP (5) JP6585625B2 (pl)
KR (2) KR102258522B1 (pl)
CN (2) CN111228274A (pl)
AU (4) AU2015209452C1 (pl)
BR (1) BR112016016975B1 (pl)
CA (2) CA3155599A1 (pl)
DK (1) DK3096756T3 (pl)
ES (1) ES2984706T3 (pl)
FI (1) FI3096756T3 (pl)
HR (1) HRP20241046T1 (pl)
HU (1) HUE068315T2 (pl)
IL (5) IL317035A (pl)
LT (1) LT3096756T (pl)
MX (3) MX389004B (pl)
NZ (1) NZ722122A (pl)
PL (1) PL3096756T3 (pl)
PT (1) PT3096756T (pl)
RS (1) RS65839B1 (pl)
RU (1) RU2718918C2 (pl)
SI (1) SI3096756T1 (pl)
SM (1) SMT202400361T1 (pl)
WO (1) WO2015112642A1 (pl)

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FI3096756T3 (fi) * 2014-01-21 2024-08-14 Neurocrine Biosciences Inc Crf1-reseptorin antagonisteja synnynnäisen lisämunuaisen liikakasvun hoitoon
US9688754B2 (en) 2014-02-20 2017-06-27 Alder Biopharmaceuticals, Inc. Anti-ACTH antibodies and use thereof
CA3039026A1 (en) 2016-09-07 2018-03-15 The Regents Of The University Of California Allosteric corticotropin-releasing factor receptor 1 (crfr1) antagonists that decrease p-tau and improve cognition
KR20250022913A (ko) * 2017-08-14 2025-02-17 스프루스 바이오사이언시스 인코포레이티드 코티코트로핀 방출 인자 수용체 길항제
EP4438124A3 (en) * 2018-04-27 2024-12-18 Spruce Biosciences, Inc. Methods for treating testicular and ovarian adrenal rest tumors
JP7532328B2 (ja) * 2018-12-07 2024-08-13 ニューロクライン バイオサイエンシーズ,インコーポレイテッド 先天性副腎過形成を処置するためのcrf1受容体アンタゴニスト、その医薬製剤および固体形態
TW202446384A (zh) * 2018-12-07 2024-12-01 美商紐羅克里生物科學有限公司 用於治療先天性腎上腺增生之crf1受體拮抗劑、醫藥配方及其固體形式
CA3147891A1 (en) * 2019-07-19 2021-01-28 Spruce Biosciences, Inc. Methods of treating congenital adrenal hyperplasia
WO2021062246A1 (en) * 2019-09-27 2021-04-01 Neurocrine Biosciences, Inc. Crf receptor antagonists and methods of use
CR20220624A (es) * 2020-06-10 2023-07-06 Sanofi Sa Antagonista del receptor crf1 para el tratamiento de la hiperplasia suprarrenal congénita
AU2021324839B2 (en) * 2020-08-12 2024-02-29 Spruce Biosciences, Inc. Methods and compositions for treating polycystic ovary syndrome
MD20210019A2 (ro) 2021-04-12 2022-10-31 Максим МАСЮТИН Metodă de tratament a hiperplaziei suprarenale congenitale, cauzate de deficit de 21-hidroxilază cu debut tardiv prin regimul de glucocorticoizi adaptat individual
US11708372B2 (en) 2021-11-19 2023-07-25 Spruce Biosciences, Inc. Crystalline composition of tildacerfont and methods of use and preparation thereof

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Also Published As

Publication number Publication date
EP4450070A1 (en) 2024-10-23
AU2020207774B2 (en) 2022-08-04
CN106102740A (zh) 2016-11-09
US11311544B2 (en) 2022-04-26
AU2020207774A1 (en) 2020-08-06
PT3096756T (pt) 2024-08-26
US20210361659A1 (en) 2021-11-25
CN111228274A (zh) 2020-06-05
US20190231781A1 (en) 2019-08-01
EP3096756A1 (en) 2016-11-30
IL304134B1 (en) 2024-12-01
JP2024098001A (ja) 2024-07-19
CA3155599A1 (en) 2015-07-30
JP2020138978A (ja) 2020-09-03
US20240058342A1 (en) 2024-02-22
HUE068315T2 (hu) 2024-12-28
MX389004B (es) 2025-03-20
IL296683B1 (en) 2023-08-01
EP3096756B1 (en) 2024-06-12
IL246783B (en) 2021-10-31
JP6585625B2 (ja) 2019-10-02
JP2019081814A (ja) 2019-05-30
LT3096756T (lt) 2024-08-26
IL317035A (en) 2025-01-01
HRP20241046T1 (hr) 2024-11-08
JP7104743B2 (ja) 2022-07-21
IL304134A (en) 2023-09-01
DK3096756T3 (da) 2024-08-05
AU2015209452A1 (en) 2016-08-04
JP6936825B2 (ja) 2021-09-22
JP2017503030A (ja) 2017-01-26
IL286782A (en) 2021-10-31
AU2015209452B2 (en) 2020-05-07
NZ722122A (en) 2020-06-26
US20210137926A1 (en) 2021-05-13
KR102258522B1 (ko) 2021-05-31
MX2022000080A (es) 2022-02-03
IL296683B2 (en) 2023-12-01
IL296683A (en) 2022-11-01
AU2024219813A1 (en) 2024-10-10
KR20210064407A (ko) 2021-06-02
RS65839B1 (sr) 2024-09-30
RU2016133972A (ru) 2018-03-05
AU2015209452C1 (en) 2020-11-05
US11730739B2 (en) 2023-08-22
CA2936974A1 (en) 2015-07-30
SI3096756T1 (sl) 2024-09-30
BR112016016975A2 (pt) 2017-08-08
US10905690B2 (en) 2021-02-02
IL246783A0 (en) 2016-08-31
AU2022263460B2 (en) 2024-10-17
RU2020112197A (ru) 2020-05-21
JP2022010260A (ja) 2022-01-14
MX2021012539A (es) 2021-11-12
RU2718918C2 (ru) 2020-04-15
SMT202400361T1 (it) 2024-11-15
MX2016009499A (es) 2017-02-27
KR20160106176A (ko) 2016-09-09
IL304134B2 (en) 2025-04-01
AU2022263460A1 (en) 2022-12-08
WO2015112642A1 (en) 2015-07-30
FI3096756T3 (fi) 2024-08-14
RU2016133972A3 (pl) 2018-09-26
BR112016016975B1 (pt) 2022-12-27
ES2984706T3 (es) 2024-10-30
US20170020877A1 (en) 2017-01-26

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