PT1869049E - Compostos de imidazopiridazina - Google Patents

Compostos de imidazopiridazina Download PDF

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Publication number
PT1869049E
PT1869049E PT06738924T PT06738924T PT1869049E PT 1869049 E PT1869049 E PT 1869049E PT 06738924 T PT06738924 T PT 06738924T PT 06738924 T PT06738924 T PT 06738924T PT 1869049 E PT1869049 E PT 1869049E
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PT
Portugal
Prior art keywords
compounds
imidazopyridazine compounds
crf1
formula
imidazopyridazine
Prior art date
Application number
PT06738924T
Other languages
English (en)
Inventor
Richard Craig Thompson
Philip Arthur Hipskind
Erik James Hembre
Heather Janelle Barbosa
Elizabeth Aaron Collins
Chafiq Hamdouchi
Richard Duane Johnston
Jianliang Lu
Michael John Rupp
Takako Takakuwa
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PT1869049E publication Critical patent/PT1869049E/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
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    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
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    • A61P37/00—Drugs for immunological or allergic disorders
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Transplantation (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Communicable Diseases (AREA)
PT06738924T 2005-03-21 2006-03-20 Compostos de imidazopiridazina PT1869049E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US66381605P 2005-03-21 2005-03-21

Publications (1)

Publication Number Publication Date
PT1869049E true PT1869049E (pt) 2009-05-26

Family

ID=36753943

Family Applications (1)

Application Number Title Priority Date Filing Date
PT06738924T PT1869049E (pt) 2005-03-21 2006-03-20 Compostos de imidazopiridazina

Country Status (25)

Country Link
US (1) US7612067B2 (pt)
EP (1) EP1869049B1 (pt)
JP (1) JP4971300B2 (pt)
KR (1) KR20070120963A (pt)
CN (1) CN101142217B (pt)
AT (1) ATE424402T1 (pt)
AU (1) AU2006227300B2 (pt)
BR (1) BRPI0608857A2 (pt)
CA (1) CA2600478C (pt)
CR (1) CR9389A (pt)
CY (1) CY1109069T1 (pt)
DE (1) DE602006005477D1 (pt)
DK (1) DK1869049T3 (pt)
EA (1) EA012393B1 (pt)
ES (1) ES2321446T3 (pt)
IL (1) IL185014A0 (pt)
MA (1) MA29437B1 (pt)
MX (1) MX2007011600A (pt)
NO (1) NO20074961L (pt)
PL (1) PL1869049T3 (pt)
PT (1) PT1869049E (pt)
SI (1) SI1869049T1 (pt)
TN (1) TNSN07358A1 (pt)
WO (1) WO2006102194A1 (pt)
ZA (1) ZA200706715B (pt)

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MA29437B1 (fr) 2008-05-02
IL185014A0 (en) 2007-12-03
US7612067B2 (en) 2009-11-03
NO20074961L (no) 2007-10-17
JP4971300B2 (ja) 2012-07-11
ZA200706715B (en) 2008-10-29
ATE424402T1 (de) 2009-03-15
EA200702044A1 (ru) 2008-02-28
JP2008533201A (ja) 2008-08-21
DK1869049T3 (da) 2009-05-18
EP1869049B1 (en) 2009-03-04
BRPI0608857A2 (pt) 2012-08-28
EP1869049A1 (en) 2007-12-26
PL1869049T3 (pl) 2009-07-31
EA012393B1 (ru) 2009-10-30
WO2006102194A1 (en) 2006-09-28
US20080113978A1 (en) 2008-05-15
CR9389A (es) 2007-12-07
ES2321446T3 (es) 2009-06-05
CY1109069T1 (el) 2014-07-02
CA2600478C (en) 2013-02-05
DE602006005477D1 (en) 2009-04-16
CA2600478A1 (en) 2006-09-28
CN101142217B (zh) 2010-12-08
CN101142217A (zh) 2008-03-12
TNSN07358A1 (en) 2008-12-31
KR20070120963A (ko) 2007-12-26
SI1869049T1 (sl) 2009-08-31
AU2006227300A1 (en) 2006-09-28
AU2006227300B2 (en) 2012-02-02

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