RS60089B1 - Novi kompleks koji sadrži peptid koji penetrira u ćeliju, teret i tlr peptidni agonist za tretman kolorektalnog kancera - Google Patents

Novi kompleks koji sadrži peptid koji penetrira u ćeliju, teret i tlr peptidni agonist za tretman kolorektalnog kancera

Info

Publication number
RS60089B1
RS60089B1 RS20200337A RSP20200337A RS60089B1 RS 60089 B1 RS60089 B1 RS 60089B1 RS 20200337 A RS20200337 A RS 20200337A RS P20200337 A RSP20200337 A RS P20200337A RS 60089 B1 RS60089 B1 RS 60089B1
Authority
RS
Serbia
Prior art keywords
complex
peptide
epitope
cell
antigen
Prior art date
Application number
RS20200337A
Other languages
English (en)
Serbian (sr)
Inventor
Madiha Derouazi
Elodie Belnoue
Original Assignee
Amal Therapeutics Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amal Therapeutics Sa filed Critical Amal Therapeutics Sa
Publication of RS60089B1 publication Critical patent/RS60089B1/sr

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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
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    • A61K39/0011—Cancer antigens
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    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
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    • A61K47/6425—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a receptor, e.g. CD4, a cell surface antigen, i.e. not a peptide ligand targeting the antigen, or a cell surface determinant, i.e. a part of the surface of a cell
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    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
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    • C07K7/04—Linear peptides containing only normal peptide links
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    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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    • C07K—PEPTIDES
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    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
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RS20200337A 2015-03-16 2016-03-16 Novi kompleks koji sadrži peptid koji penetrira u ćeliju, teret i tlr peptidni agonist za tretman kolorektalnog kancera RS60089B1 (sr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP2015000580 2015-03-16
EP2015002244 2015-11-09
EP16711529.4A EP3270955B1 (en) 2015-03-16 2016-03-16 A novel complex comprising a cell penetrating peptide, a cargo and a tlr peptide agonist for treatment of colorectal cancer
PCT/EP2016/000473 WO2016146262A1 (en) 2015-03-16 2016-03-16 A novel complex comprising a cell penetrating peptide, a cargo and a tlr peptide agonist for treatment of colorectal cancer

Publications (1)

Publication Number Publication Date
RS60089B1 true RS60089B1 (sr) 2020-05-29

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Application Number Title Priority Date Filing Date
RS20200337A RS60089B1 (sr) 2015-03-16 2016-03-16 Novi kompleks koji sadrži peptid koji penetrira u ćeliju, teret i tlr peptidni agonist za tretman kolorektalnog kancera

Country Status (24)

Country Link
US (7) US20180133327A1 (OSRAM)
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