RS49611B - Ziprasidon formulacije - Google Patents
Ziprasidon formulacijeInfo
- Publication number
- RS49611B RS49611B YUP-271/99A YU27199A RS49611B RS 49611 B RS49611 B RS 49611B YU 27199 A YU27199 A YU 27199A RS 49611 B RS49611 B RS 49611B
- Authority
- RS
- Serbia
- Prior art keywords
- ziprasidone
- formulations
- crystalline
- ziprasidone formulations
- carrier
- Prior art date
Links
- 229960000607 ziprasidone Drugs 0.000 title abstract 3
- MVWVFYHBGMAFLY-UHFFFAOYSA-N ziprasidone Chemical compound C1=CC=C2C(N3CCN(CC3)CCC3=CC=4CC(=O)NC=4C=C3Cl)=NSC2=C1 MVWVFYHBGMAFLY-UHFFFAOYSA-N 0.000 title abstract 3
- 238000009472 formulation Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 229960003474 ziprasidone hydrochloride Drugs 0.000 abstract 1
- ZCBZSCBNOOIHFP-UHFFFAOYSA-N ziprasidone hydrochloride hydrate Chemical compound [H+].O.[Cl-].C1=CC=C2C(N3CCN(CC3)CCC3=CC=4CC(=O)NC=4C=C3Cl)=NSC2=C1 ZCBZSCBNOOIHFP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polyamides (AREA)
- Detergent Compositions (AREA)
- Feeding Of Articles By Means Other Than Belts Or Rollers (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Ziprasidon formulacije, naznačene time, što sadrže kristalnu slobodnu bazu ziprasidona ili kristalne ziprasidon hidrohlorid čestice koje imaju srednju veličinu jednaku ili manju od oko 85 μm i farmaceutski prihvatljiv razblaživač ili nosilac. Prijava sadrži još 9 patentnih zahteva.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8922998P | 1998-06-15 | 1998-06-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
YU27199A YU27199A (sh) | 2002-12-10 |
RS49611B true RS49611B (sr) | 2007-06-04 |
Family
ID=22216447
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YUP-271/99A RS49611B (sr) | 1998-06-15 | 1999-06-14 | Ziprasidon formulacije |
Country Status (45)
Families Citing this family (66)
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US20080113025A1 (en) * | 1998-11-02 | 2008-05-15 | Elan Pharma International Limited | Compositions comprising nanoparticulate naproxen and controlled release hydrocodone |
US7175855B1 (en) * | 1999-05-27 | 2007-02-13 | Pfizer Inc. | Ziprasidone suspension |
OA11946A (en) * | 1999-05-27 | 2006-04-13 | Pfizer Prod Inc | Ziprasidone suspension. |
US10179130B2 (en) | 1999-10-29 | 2019-01-15 | Purdue Pharma L.P. | Controlled release hydrocodone formulations |
IL149352A0 (en) | 1999-10-29 | 2002-11-10 | Euro Celtique Sa | Controlled release hydrocodone formulations |
EP2295042A1 (en) | 2000-10-30 | 2011-03-16 | Euro-Celtique S.A. | Controlled release hydrocodone formulations |
UY27668A1 (es) * | 2002-02-20 | 2003-10-31 | Pfizer Prod Inc | Composición de ziprasidona y controles sintéticos |
US20040048876A1 (en) * | 2002-02-20 | 2004-03-11 | Pfizer Inc. | Ziprasidone composition and synthetic controls |
JP4545584B2 (ja) | 2002-05-17 | 2010-09-15 | デューク ユニバーシティ | 肥満を治療するための方法 |
WO2004050655A1 (en) * | 2002-12-04 | 2004-06-17 | Dr. Reddy's Laboratories Limited | Polymorphic forms of ziprasidone and its hydrochloride |
US7488729B2 (en) * | 2002-12-04 | 2009-02-10 | Dr. Reddy's Laboratories Limited | Polymorphic forms of ziprasidone and its hydrochloride salt and process for preparation thereof |
WO2004089948A1 (en) * | 2003-04-11 | 2004-10-21 | Hetero Drugs Limited | Novel crystalline forms of ziprasidone hydrochloride |
PL1617832T3 (pl) | 2003-04-29 | 2009-01-30 | Orexigen Therapeutics Inc | Kompozycje wpływające na utratę wagi |
KR100880279B1 (ko) * | 2003-06-03 | 2009-01-28 | 테바 파마슈티컬 인더스트리즈 리미티드 | 결정성 지프라시돈 염산염 및 그의 제조 방법 |
US20050049295A1 (en) * | 2003-06-12 | 2005-03-03 | Dr. Reddy's Laboratories Limited | Process for the preparation of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1piperazinyl) ethyl)-6-chloro-1, 3-dihydro-2h-indol-2-one hydrochloride (ziprasidone hydrochloride) and its intermediate |
KR20090080143A (ko) * | 2003-09-02 | 2009-07-23 | 화이자 프로덕츠 인크. | 지프라시돈의 지속 방출형 투여 형태 |
US7667037B2 (en) * | 2003-10-24 | 2010-02-23 | Teva Pharmaceutical Industries Ltd. | Processes for preparation of ziprasidone |
AU2003285600A1 (en) * | 2003-11-28 | 2005-06-24 | Siddiqui Mohammed Jaweed Mukarram | Process for the preparing ziprasidone monohydrochloride hydrate |
CA2550485A1 (en) * | 2003-12-18 | 2005-07-07 | Teva Pharmaceutical Industries Ltd. | Polymorphic form b2 of ziprasidone base |
CA2552126A1 (en) * | 2003-12-31 | 2005-07-21 | Actavis Group Hf | Ziprasidone formulations |
KR20060128995A (ko) * | 2004-01-13 | 2006-12-14 | 듀크 유니버시티 | 체중감량에 영향을 미치는 항경련제와 항정신병 약물의조성물 |
US7713959B2 (en) * | 2004-01-13 | 2010-05-11 | Duke University | Compositions of an anticonvulsant and mirtazapine to prevent weight gain |
ES2334800T3 (es) * | 2004-02-27 | 2010-03-16 | Ranbaxy Laboratories Limited | Proceso para la preparacion de ziprasidona. |
JP2007536229A (ja) * | 2004-05-03 | 2007-12-13 | デューク・ユニバーシティー | 体重減少に作用するための組成物 |
EP1744750A2 (en) * | 2004-05-06 | 2007-01-24 | Sandoz AG | Pharmaceutical composition comprising hydrophobic drug having improved solubility |
CA2467538C (en) * | 2004-05-14 | 2010-08-24 | Apotex Pharmachem Inc. | New amorphous ziprasidone hydrochloride (5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2h-indol-2-one hydrochloride) and processes to produce the same |
EP1753400A4 (en) * | 2004-06-11 | 2012-11-28 | Reddys Lab Ltd Dr | PHARMACEUTICAL FOR ZIPRASIDONE |
CA2471219A1 (en) * | 2004-06-14 | 2005-12-14 | Apotex Pharmachem Inc. | Improved preparation of an anhydrate form of 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2h-indol-2-one hydrochloride (ziprasidone hydrochloride) |
WO2006026426A2 (en) * | 2004-08-27 | 2006-03-09 | University Of Kentucky Research Foundation | Amyloid peptide inactivating enzyme to treat alzheimer’s disease peripherally |
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WO2006055603A2 (en) * | 2004-11-16 | 2006-05-26 | Elan Pharma International Ltd. | Injectable nanoparticulate olanzapine formulations |
WO2006085168A2 (en) * | 2005-01-07 | 2006-08-17 | Ranbaxy Laboratories Limited | Solid oral dosage forms of ziprasidone containing colloidal silicone dioxide |
US7749529B2 (en) * | 2005-02-08 | 2010-07-06 | Ash Access Technology, Inc. | Catheter lock solution comprising citrate and a paraben |
US20070032511A1 (en) * | 2005-02-11 | 2007-02-08 | Judith Aronhime | Amorphous ziprasidone mesylate |
ITMI20050346A1 (it) | 2005-03-07 | 2006-09-08 | Dipharma Spa | Forma solida di ziprasidone cloridrato |
CA2500667C (en) * | 2005-03-11 | 2013-01-15 | Apotex Pharmachem Inc. | Preparation of acid addition salts of ziprasidone and intermediates thereof by solid phase-gas phase reactions |
US20060270684A1 (en) * | 2005-03-14 | 2006-11-30 | Judith Aronhime | Crystalline forms of ziprasidone mesylate |
US20060270685A1 (en) * | 2005-03-14 | 2006-11-30 | Judith Aronhime | Anhydrous ziprasidone mesylate and a process for its preparation |
US20080305161A1 (en) * | 2005-04-13 | 2008-12-11 | Pfizer Inc | Injectable depot formulations and methods for providing sustained release of nanoparticle compositions |
AU2006233345A1 (en) * | 2005-04-13 | 2006-10-19 | Pfizer Products Inc. | Injectable depot formulations and methods for providing sustained release of nanoparticle compositions |
CN101198323A (zh) * | 2005-04-22 | 2008-06-11 | 惠氏公司 | 用于治疗或预防精神障碍的治疗组合 |
CN101184489B (zh) | 2005-05-26 | 2011-01-19 | 大日本住友制药株式会社 | 药物组合物 |
CN101879140A (zh) * | 2005-06-20 | 2010-11-10 | 依兰药物国际有限公司 | 包含芳基-杂环化合物的毫微粒和控制释放组合物 |
CN101242813A (zh) * | 2005-06-20 | 2008-08-13 | 依兰药物国际有限公司 | 包含芳基-杂环化合物的毫微粒和控制释放组合物 |
ES2761812T3 (es) | 2005-11-22 | 2020-05-21 | Nalpropion Pharmaceuticals Inc | Composición y métodos de aumento de la sensibilidad a la insulina |
DK1954241T3 (da) * | 2005-11-28 | 2012-06-18 | Orexigen Therapeutics Inc | Zonisamid-formulering med vedvarende frigivelse |
PL379569A1 (pl) * | 2006-04-28 | 2007-10-29 | Pliva Kraków Zakłady Farmaceutyczne Spółka Akcyjna | Sposób wytwarzania kompozycji farmaceutycznej zawierającej substancję aktywną ziprasidone lub jego farmaceutycznie dopuszczalną sól zwiększający rozpuszczalność i biodostępność tego leku, kompozycja farmaceutyczna i zastosowanie hydrofilowych substancji pomocniczych |
US8916195B2 (en) | 2006-06-05 | 2014-12-23 | Orexigen Therapeutics, Inc. | Sustained release formulation of naltrexone |
EP1889844A3 (en) * | 2006-08-02 | 2008-03-05 | Krka | Polymorphic forms of ziprasidone sulphates |
EP1892243A1 (en) * | 2006-08-02 | 2008-02-27 | KRKA, tovarna zdravil, d.d., Novo mesto | Polymorphic forms of ziprasidone sulphate salts |
AU2007319472B2 (en) | 2006-11-09 | 2013-01-17 | Nalpropion Pharmaceuticals Llc | Methods Of Administering Weight Loss Medications |
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JP2010527925A (ja) * | 2007-05-18 | 2010-08-19 | サイドース・エルエルシー | ジプラシドン製剤 |
EP2197446A4 (en) * | 2007-08-31 | 2012-01-25 | Reddys Lab Ltd Dr | PREPARATION OF HYDROCHLORIDE OF ZIPRASIDONE MONOHYDRATE |
US8410268B2 (en) * | 2008-03-11 | 2013-04-02 | Alkem Laboratories Limited | Process for the preparation of ziprasidone |
CA2725930A1 (en) | 2008-05-30 | 2009-12-30 | Orexigen Therapeutics, Inc. | Methods for treating visceral fat conditions |
DE102008045854A1 (de) | 2008-09-05 | 2010-03-11 | Tiefenbacher Pharmachemikalien Alfred E. Tiefenbacher Gmbh & Co. Kg | Partikel aus Ziprasidone und einem Sprengmittel enthaltende Pharmazeutische Zusammensetzung |
JP5732453B2 (ja) | 2009-06-25 | 2015-06-10 | アルカーメス ファーマ アイルランド リミテッド | Nh酸性化合物のプロドラッグ |
EP2340834A1 (en) | 2009-12-30 | 2011-07-06 | Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi | Enhanced Solubility of Ziprasidone |
CN102724878A (zh) | 2010-01-11 | 2012-10-10 | 奥雷西根治疗公司 | 在重度抑郁症患者中提供体重减轻疗法的方法 |
DK3017811T3 (en) | 2010-02-25 | 2019-04-01 | Bristol Myers Squibb Holdings Ireland | APIXABAN FORMULATIONS |
WO2011148253A2 (en) | 2010-05-25 | 2011-12-01 | Aurobindo Pharma Limited | Solid dosage forms of antipsychotics |
SI23610A (sl) | 2011-01-13 | 2012-07-31 | Diagen@d@o@o | Nove adicijske soli ziprasidona postopek za njihovo pripravo in njihova uporaba v terapiji |
IN2015DN00042A (sr) | 2012-06-06 | 2015-05-22 | Orexigen Therapeutics Inc | |
US10154988B2 (en) | 2012-11-14 | 2018-12-18 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
EP3761983A1 (en) | 2018-03-05 | 2021-01-13 | Alkermes Pharma Ireland Limited | Aripiprazole dosing strategy |
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-
1999
- 1999-05-27 US US09/320,985 patent/US6150366A/en not_active Expired - Lifetime
- 1999-06-04 HN HN1999000089A patent/HN1999000089A/es unknown
- 1999-06-08 DK DK99304451T patent/DK0965343T3/da active
- 1999-06-08 PT PT99304451T patent/PT965343E/pt unknown
- 1999-06-08 EP EP99304451A patent/EP0965343B1/en not_active Expired - Lifetime
- 1999-06-08 SI SI9930316T patent/SI0965343T1/xx unknown
- 1999-06-08 DE DE69908021T patent/DE69908021T2/de not_active Expired - Lifetime
- 1999-06-08 GT GT199900080A patent/GT199900080A/es unknown
- 1999-06-08 AT AT99304451T patent/ATE240732T1/de active
- 1999-06-08 ES ES99304451T patent/ES2197581T3/es not_active Expired - Lifetime
- 1999-06-09 SK SK769-99A patent/SK286245B6/sk not_active IP Right Cessation
- 1999-06-09 TW TW088109645A patent/TW590774B/zh not_active IP Right Cessation
- 1999-06-09 AU AU33983/99A patent/AU753820B2/en not_active Ceased
- 1999-06-10 SG SG1999002794A patent/SG77243A1/en unknown
- 1999-06-10 IL IL13042496A patent/IL130424A/xx not_active IP Right Cessation
- 1999-06-10 AP APAP/P/1999/001579A patent/AP1216A/en active
- 1999-06-11 CA CA002274338A patent/CA2274338C/en not_active Expired - Lifetime
- 1999-06-11 MY MYPI99002412A patent/MY121397A/en unknown
- 1999-06-11 AR ARP990102822A patent/AR015553A1/es active IP Right Grant
- 1999-06-11 PE PE1999000523A patent/PE20000632A1/es not_active Application Discontinuation
- 1999-06-11 IS IS5079A patent/IS2182B/is unknown
- 1999-06-11 TR TR1999/01379A patent/TR199901379A2/xx unknown
- 1999-06-14 NO NO19992892A patent/NO316713B1/no not_active IP Right Cessation
- 1999-06-14 KR KR1019990021977A patent/KR100338915B1/ko not_active IP Right Cessation
- 1999-06-14 OA OA9900126A patent/OA11064A/en unknown
- 1999-06-14 HU HU9901960A patent/HU226487B1/hu not_active IP Right Cessation
- 1999-06-14 JP JP16677399A patent/JP3441676B2/ja not_active Expired - Lifetime
- 1999-06-14 CN CNB991111192A patent/CN1307994C/zh not_active Expired - Fee Related
- 1999-06-14 HR HR990193A patent/HRP990193B1/xx not_active IP Right Cessation
- 1999-06-14 BG BG103489A patent/BG64691B1/bg unknown
- 1999-06-14 MA MA25621A patent/MA26647A1/fr unknown
- 1999-06-14 PL PL380276A patent/PL195606B1/pl not_active IP Right Cessation
- 1999-06-14 PL PL333737A patent/PL195209B1/pl not_active IP Right Cessation
- 1999-06-14 NZ NZ336271A patent/NZ336271A/xx not_active IP Right Cessation
- 1999-06-14 RS YUP-271/99A patent/RS49611B/sr unknown
- 1999-06-14 CZ CZ0212799A patent/CZ297954B6/cs not_active IP Right Cessation
- 1999-06-14 PA PA19998475601A patent/PA8475601A1/es unknown
- 1999-06-14 ID IDP990571D patent/ID23546A/id unknown
- 1999-06-14 ZA ZA9903938A patent/ZA993938B/xx unknown
- 1999-06-14 UA UA99063279A patent/UA59383C2/uk unknown
- 1999-06-15 BR BR9902268-0A patent/BR9902268A/pt not_active Application Discontinuation
- 1999-06-15 CO CO99037319A patent/CO5070579A1/es unknown
- 1999-06-15 EA EA199900467A patent/EA002223B1/ru not_active IP Right Cessation
- 1999-08-10 UY UY25649A patent/UY25649A1/es unknown
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2000
- 2000-06-16 HK HK00103630A patent/HK1024184A1/xx not_active IP Right Cessation
-
2001
- 2001-06-11 JP JP2001175276A patent/JP4187423B2/ja not_active Expired - Lifetime
-
2003
- 2003-11-20 CY CY200300002C patent/CY2003002I1/el unknown
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