RS51003B - Derivat piridin-1-oksida i postupak za njegovu transformaciju u farmaceutski efikasna jedinjenja - Google Patents

Derivat piridin-1-oksida i postupak za njegovu transformaciju u farmaceutski efikasna jedinjenja

Info

Publication number
RS51003B
RS51003B YUP-783/02A YUP78302A RS51003B RS 51003 B RS51003 B RS 51003B YU P78302 A YUP78302 A YU P78302A RS 51003 B RS51003 B RS 51003B
Authority
RS
Serbia
Prior art keywords
piridine
transformation
pharmaceutically effective
oxide derivative
effective compounds
Prior art date
Application number
YUP-783/02A
Other languages
English (en)
Inventor
László ÜRÖGDI
Zita JEGESNÉ CSÁKAI
Lajos Gruber
László ÖTVÖS
József TOTH
István TÖMÖSKÖZI
Anikó SZAKÁCSNÉ SCHMIDT
Ferencné REIDER
Mária SCHNEIDERNÉ BARLAY
Original Assignee
Cytrx Corporation A Delaware Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytrx Corporation A Delaware Corporation filed Critical Cytrx Corporation A Delaware Corporation
Publication of YU78302A publication Critical patent/YU78302A/sh
Publication of RS51003B publication Critical patent/RS51003B/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

N-[2-hidroksi-3-(l-piperidinil)-propoksi]-piridin-l-oksid-3-karboksamidin ili njegova farmaceutski prihvatljiva so. Prijava sadrži još 7 patentnih zahteva.
YUP-783/02A 2000-04-18 2001-04-17 Derivat piridin-1-oksida i postupak za njegovu transformaciju u farmaceutski efikasna jedinjenja RS51003B (sr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU0001583A HUP0001583A2 (hu) 2000-04-18 2000-04-18 Egy piridin-1-oxid-származék és eljárás annak átalakítására gyógyászati hatású vegyületekké

Publications (2)

Publication Number Publication Date
YU78302A YU78302A (sh) 2005-09-19
RS51003B true RS51003B (sr) 2010-10-31

Family

ID=90001563

Family Applications (1)

Application Number Title Priority Date Filing Date
YUP-783/02A RS51003B (sr) 2000-04-18 2001-04-17 Derivat piridin-1-oksida i postupak za njegovu transformaciju u farmaceutski efikasna jedinjenja

Country Status (32)

Country Link
US (1) US7126002B2 (sr)
EP (1) EP1274685B1 (sr)
JP (1) JP5066638B2 (sr)
KR (1) KR100742482B1 (sr)
CN (1) CN1216868C (sr)
AT (1) ATE332894T1 (sr)
AU (2) AU5499701A (sr)
BG (1) BG65889B1 (sr)
BR (1) BRPI0110184B8 (sr)
CA (1) CA2406266C (sr)
CY (1) CY1107473T1 (sr)
CZ (1) CZ301576B6 (sr)
DE (1) DE60121431T2 (sr)
DK (1) DK1274685T3 (sr)
EE (1) EE05085B1 (sr)
ES (1) ES2267758T3 (sr)
HK (1) HK1055741A1 (sr)
HR (1) HRP20020825A2 (sr)
HU (1) HUP0001583A2 (sr)
IL (2) IL152337A0 (sr)
MX (1) MXPA02010320A (sr)
NO (1) NO323535B1 (sr)
NZ (1) NZ522017A (sr)
PL (1) PL359826A1 (sr)
PT (1) PT1274685E (sr)
RS (1) RS51003B (sr)
RU (1) RU2281282C2 (sr)
SI (1) SI1274685T1 (sr)
SK (1) SK287606B6 (sr)
UA (1) UA75353C2 (sr)
WO (1) WO2001079174A1 (sr)
ZA (1) ZA200208460B (sr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP9900475D0 (en) * 1999-02-26 1999-04-28 Biorex Kutato Fejlesztoe Kft O-(3-piperidino-2-hydroxy-1-propyl)-hiyroximic acid-halogenid derivative, it's use for treating insulin resistance, and pharmaceutical compositions containing them as active component
HU0103939D0 (en) * 2001-09-27 2001-11-28 Biorex Kutato Fejlesztoe Kft Pharmaceutical composition containing methformin and n-[2-hydroxy-3-(1-piperidinyl)-propoxy]-pyridine-1-oxide-3-carboximidoyl chloride
RS60604A (en) 2002-01-11 2006-12-15 Biorex Kutato Es Feyleszto Rt. Carboxamidine derivatives and their use in the treatment of vascular diseases
HUP0303584A3 (en) 2003-10-30 2009-12-28 Cytrx Corp Use of a hydroximic acid halide derivative in the treatment of neurodegenerative diseases
WO2008039514A1 (en) * 2006-09-26 2008-04-03 Cytrx Corporation Pharmaceutical compositions and methods for treating diseases associated with neurodegeneration
BR122019024895B8 (pt) 2008-06-26 2021-07-27 Orphazyme As uso de um agente bioativo capaz de aumentar a concentração intracelular de hsp70
AU2011335545A1 (en) 2010-11-30 2013-06-13 Orphazyme Aps Methods for increasing intracellular activity of Hsp70
HUP1100534A2 (en) 2011-09-26 2013-04-29 Balazs Dr Hazay Pharmaceutical composition for the treatment of muscle atrophy
HUP1100535A2 (en) 2011-09-26 2013-04-29 Bracelia Invest Ltd Pharmaceutical composition for enhancement of stem cell treatment
BR112017004948A2 (pt) 2014-09-15 2017-12-05 Orphazyme Aps formulação farmacêutica.
US10898476B2 (en) 2016-04-13 2021-01-26 Orphazyme A/S Heat shock proteins and cholesterol homeostasis
US20190111041A1 (en) 2016-04-29 2019-04-18 Orphazyme A/S Arimoclomol for treating glucocerebrosidase associated disorders
HUP1800298A1 (hu) 2018-08-30 2020-05-28 N Gene Res Laboratories Inc Gyógyszerkombináció béta-receptor blokkolók hatásának módosítására és a mellékhatások csökkentésére
KR20230035586A (ko) 2020-06-24 2023-03-14 켐팜 덴마크 에이/에스 고셔병을 치료하기 위한 아리모클로몰
KR20230128462A (ko) 2020-11-19 2023-09-05 제브라 덴마크 에이/에스 아리모클로몰 시트레이트 및 이의 중간체를 제조하기 위한 공정
AU2021405780A1 (en) 2020-12-24 2023-07-06 Zevra Denmark A/S Arimoclomol for the treatment of niemann pick disease, type c, in patients with er type missense mutations

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU207988B (en) * 1988-10-20 1993-07-28 Biorex Kutato Fejlesztoe Kft Process for producing halogenides of o-/3-amino-2-hydroxy-propyl/hydroximic acid and pharmaceutical compositions containing them as active components
HU9502843D0 (en) 1995-09-29 1995-11-28 Livigene Ltd Pharmaceutical composition
HU222994B1 (hu) * 1995-11-02 2004-01-28 BIOREX Kutató és Fejlesztő Rt. Hidroxilaminszármazékok és azok alkalmazása sejtek molekuláris chaperon-termelésének fokozására alkalmas gyógyszerkészítmények előállítására
HUP9900475D0 (en) * 1999-02-26 1999-04-28 Biorex Kutato Fejlesztoe Kft O-(3-piperidino-2-hydroxy-1-propyl)-hiyroximic acid-halogenid derivative, it's use for treating insulin resistance, and pharmaceutical compositions containing them as active component

Also Published As

Publication number Publication date
PT1274685E (pt) 2006-09-29
DE60121431T2 (de) 2007-01-18
PL359826A1 (en) 2004-09-06
BG65889B1 (bg) 2010-04-30
SK287606B6 (sk) 2011-03-04
IL152337A0 (en) 2003-05-29
US7126002B2 (en) 2006-10-24
BRPI0110184B1 (pt) 2015-12-29
ZA200208460B (en) 2003-10-20
EE05085B1 (et) 2008-10-15
WO2001079174A1 (en) 2001-10-25
HK1055741A1 (en) 2004-01-21
KR100742482B1 (ko) 2007-07-25
HRP20020825A2 (en) 2004-12-31
EP1274685A1 (en) 2003-01-15
CZ20023445A3 (cs) 2003-03-12
SK15082002A3 (sk) 2003-05-02
IL152337A (en) 2007-10-31
NO20025015D0 (no) 2002-10-18
YU78302A (sh) 2005-09-19
CN1216868C (zh) 2005-08-31
WO2001079174A8 (en) 2002-12-27
ATE332894T1 (de) 2006-08-15
NO323535B1 (no) 2007-06-04
CA2406266A1 (en) 2001-10-25
NZ522017A (en) 2004-06-25
CA2406266C (en) 2010-07-20
MXPA02010320A (es) 2004-09-06
EP1274685B1 (en) 2006-07-12
KR20030011309A (ko) 2003-02-07
HUP0001583A2 (hu) 2002-11-28
JP5066638B2 (ja) 2012-11-07
BG107199A (bg) 2003-07-31
EE200200591A (et) 2004-04-15
JP2004501080A (ja) 2004-01-15
HUP0001583D0 (en) 2000-06-28
BR0110184A (pt) 2003-06-17
BRPI0110184B8 (pt) 2021-05-25
CZ301576B6 (cs) 2010-04-21
CY1107473T1 (el) 2012-12-19
RU2002130710A (ru) 2004-03-20
ES2267758T3 (es) 2007-03-16
RU2281282C2 (ru) 2006-08-10
UA75353C2 (en) 2006-04-17
US20040006232A1 (en) 2004-01-08
NO20025015L (no) 2002-12-16
AU5499701A (en) 2001-10-30
CN1434800A (zh) 2003-08-06
DK1274685T3 (da) 2006-11-06
DE60121431D1 (de) 2006-08-24
SI1274685T1 (sl) 2006-10-31
AU2001254997B2 (en) 2006-11-23

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