RS20060239A - Derivati arilalkilkarbamata, njihovo dobijanje i njihova primena kao terapeutika - Google Patents

Derivati arilalkilkarbamata, njihovo dobijanje i njihova primena kao terapeutika

Info

Publication number
RS20060239A
RS20060239A YUP-2006/0239A YUP20060239A RS20060239A RS 20060239 A RS20060239 A RS 20060239A YU P20060239 A YUP20060239 A YU P20060239A RS 20060239 A RS20060239 A RS 20060239A
Authority
RS
Serbia
Prior art keywords
phenyl
group
ethylcarbamate
alkyl
fluoroalkyl
Prior art date
Application number
YUP-2006/0239A
Other languages
English (en)
Serbian (sr)
Inventor
Ahmed Abouabdellah
Garcia Antonio Almario
Original Assignee
Sanofi-Aventis,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Aventis, filed Critical Sanofi-Aventis,
Priority to MEP-306/08A priority Critical patent/MEP30608A/xx
Publication of RS20060239A publication Critical patent/RS20060239A/sr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
    • C07C271/42—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/44—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
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    • A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
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    • C07C271/24—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
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  • General Health & Medical Sciences (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
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  • Physical Education & Sports Medicine (AREA)
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YUP-2006/0239A 2003-10-03 2004-10-01 Derivati arilalkilkarbamata, njihovo dobijanje i njihova primena kao terapeutika RS20060239A (sr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MEP-306/08A MEP30608A (en) 2003-10-03 2004-10-01 Arylalkylcarbamate derivatives, preparation method thereof and use of same in therapeutics

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0311615A FR2860514A1 (fr) 2003-10-03 2003-10-03 Derives d'arylalkylcarbamates, leur preparation et leur application en therapeutique
PCT/FR2004/002486 WO2005033066A2 (fr) 2003-10-03 2004-10-01 Derives d'arylalkylcarbamates, leur preparation et leur application en therapeutique sanofi-synthelabo

Publications (1)

Publication Number Publication Date
RS20060239A true RS20060239A (sr) 2008-06-05

Family

ID=34307401

Family Applications (1)

Application Number Title Priority Date Filing Date
YUP-2006/0239A RS20060239A (sr) 2003-10-03 2004-10-01 Derivati arilalkilkarbamata, njihovo dobijanje i njihova primena kao terapeutika

Country Status (20)

Country Link
US (1) US7696374B2 (enExample)
EP (2) EP1673337B1 (enExample)
JP (1) JP4822351B2 (enExample)
KR (2) KR20110093928A (enExample)
CN (1) CN1878750B (enExample)
AT (1) ATE534621T1 (enExample)
AU (2) AU2004277436B2 (enExample)
BR (1) BRPI0414855A (enExample)
CA (1) CA2539849A1 (enExample)
FR (1) FR2860514A1 (enExample)
IL (1) IL174555A0 (enExample)
MA (1) MA28074A1 (enExample)
ME (1) MEP30608A (enExample)
MX (1) MXPA06003751A (enExample)
NO (1) NO20061982L (enExample)
NZ (1) NZ546309A (enExample)
RS (1) RS20060239A (enExample)
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Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2864080B1 (fr) * 2003-12-23 2006-02-03 Sanofi Synthelabo Derives de 1-piperazine-et-1-homopiperazine-carboxylates, leur preparation et leur application en therapeutique
FR2866885B1 (fr) * 2004-02-26 2007-08-31 Sanofi Synthelabo Derives de piperidinylalkylcarbamates, leur prepation et leur application en therapeutique
FR2885364B1 (fr) 2005-05-03 2007-06-29 Sanofi Aventis Sa Derives d'alkyl-, alkenyl-et alkynylcarbamates, leur preparation et leur application en therapeutique
CN101253173A (zh) * 2005-09-02 2008-08-27 辉瑞有限公司 羟基取代的1h-咪唑并吡啶和方法
WO2007047575A2 (en) * 2005-10-14 2007-04-26 The Board Of Trustees Of The University Of Illinois Pharmacological treatments for sleep-related breathing disorders
US20080089845A1 (en) * 2006-09-07 2008-04-17 N.V. Organon Methods for determining effective doses of fatty acid amide hydrolase inhibitors in vivo
US20090099240A1 (en) * 2006-10-02 2009-04-16 N.V. Organon Methods for treating energy metabolism disorders by inhibiting fatty acid amide hydrolase activity
EP2096915A1 (en) * 2006-11-20 2009-09-09 N.V. Organon Metabolically-stabilized inhibitors of fatty acid amide hydrolase
WO2009009041A2 (en) * 2007-07-06 2009-01-15 Kinex Pharmaceuticals, Llc Compositions and methods for modulating a kinase cascade
US8207226B1 (en) 2008-06-03 2012-06-26 Alcon Research, Ltd. Use of FAAH antagonists for treating dry eye and ocular pain
WO2012058115A2 (en) * 2010-10-28 2012-05-03 Benjamin Cravatt Anti-cancer serine hydrolase inhibitory carbamates
US9926273B2 (en) 2012-08-30 2018-03-27 Athenex, Inc. Composition and methods for modulating a kinase cascade
CN105418460B (zh) * 2014-08-11 2017-04-12 苏州鹏旭医药科技有限公司 匹莫范色林及其类似化合物中间体，其制备方法和制备匹莫范色林及其类似化合物的方法
JP6980534B2 (ja) 2015-06-25 2021-12-15 ザ チルドレンズ メディカル センター コーポレーション 造血幹細胞の増大、富化、および維持に関する方法および組成物
WO2017161001A1 (en) 2016-03-15 2017-09-21 Children's Medical Center Corporation Methods and compositions relating to hematopoietic stem cell expansion
KR101978364B1 (ko) 2017-06-15 2019-05-14 크리스탈지노믹스(주) 알킬카바모일 나프탈렌일옥시 옥테노일 하이드록시아마이드 또는 그 유도체의 약학적으로 허용 가능한 염 및 그 제조방법
WO2021100942A1 (ko) * 2019-11-22 2021-05-27 재단법인 한국파스퇴르연구소 항결핵 화합물인 티에노싸이아졸카박사아마이드 유도체
US12553903B2 (en) 2023-06-01 2026-02-17 Cg Pharmaceuticals, Inc Ivaltinostat combination therapy for treating pancreatic cancer

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2954395A (en) * 1958-04-09 1960-09-27 Us Vitamin Pharm Corp Trifluoromethylphenyl carbamates
US3600427A (en) * 1967-05-08 1971-08-17 Anthony J Verbiscar Phenyl carbamate latentiated phenethylamines
DE1668085A1 (de) * 1968-01-30 1971-04-15 Bayer Ag O-Halogenphenyl-carbamate
JPS5019608B1 (enExample) * 1969-06-06 1975-07-08
JPS4931093B1 (enExample) * 1969-06-13 1974-08-19
JPS531333B1 (enExample) * 1969-09-08 1978-01-18
JPS4931094B1 (enExample) * 1969-09-08 1974-08-19
JPS4939815B1 (enExample) * 1969-09-09 1974-10-29
JPS4917572B1 (enExample) * 1970-10-21 1974-05-01
JPS5428452B2 (enExample) * 1972-03-10 1979-09-17
JPS5414781B2 (enExample) 1972-06-13 1979-06-09
JPS4931094A (enExample) 1972-07-22 1974-03-20
JPS4931093A (enExample) 1972-07-22 1974-03-20
JPS4939815A (enExample) 1972-08-23 1974-04-13
DE2326754C3 (de) 1973-05-25 1978-04-20 Eisenwerk-Gesellschaft Maximilianshuette Mbh, 8458 Sulzbach-Rosenberg Vorrichtung zum gesteuerten Zuführen eines Frischgases und eines fluiden Schutzmediums
JPS531333A (en) 1976-06-04 1978-01-09 Matsushita Electric Ind Co Ltd Seath heater
JPS56103222A (en) * 1980-01-22 1981-08-18 Mitsui Toatsu Chem Inc Preparation of polyurethane
SU1363772A1 (ru) * 1985-07-23 2000-02-27 Уфимский Нефтяной Институт Способ получения изопропил-n-фенилкарбамата
DE3815046A1 (de) * 1988-05-04 1989-11-16 Basf Ag 3-chlor-2-methylphenethylaminoderivate
IL95994A0 (en) * 1989-11-15 1991-07-18 American Home Prod Carbamate esters and pharmaceutical compositions containing them
US5112859A (en) * 1990-09-14 1992-05-12 American Home Products Corporation Biphenyl amide cholesterol ester hydrolase inhibitors
ES2087038B1 (es) * 1994-11-07 1997-03-16 Uriach & Cia Sa J Nuevas piperidinas con actividad antagonista del paf.
TW375612B (en) * 1995-04-06 1999-12-01 Janssen Pharmaceutica Nv 1,3-dihydro-2H-imidazol-2-one derivatives for the treatment of disease states related to an abnormal enzymatic or catalytic activity of phosphodiesterase type IV, preparation thereof and pharmaceutical composition containing the same
US5756507A (en) * 1995-12-14 1998-05-26 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
WO1997021435A1 (en) * 1995-12-14 1997-06-19 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
NZ331104A (en) * 1995-12-29 2000-03-27 Boehringer Ingelheim Ca Ltd Phenyl thiazole derivatives that inhibit herpes replication by inhibiting the herpes helicase primase enzyme complex
WO1998035936A1 (en) * 1997-02-14 1998-08-20 Ube Industries, Ltd. Process for producing aryl carbamates
JP3480296B2 (ja) * 1997-02-14 2003-12-15 宇部興産株式会社 カルバメートの製造方法
KR100544528B1 (ko) * 1998-02-09 2006-01-23 엘파트로닉 아게 컨베이어 장치
PE20000942A1 (es) * 1998-07-31 2000-09-28 Lilly Co Eli Derivados de amida, carbamato y urea
EP1303481A1 (en) * 2000-07-26 2003-04-23 Patrick Anthony Riley Phenylethylamine derivatives and their use in the treatment of melanoma
HN2001000224A (es) * 2000-10-19 2002-06-13 Pfizer Compuestos de imidazol condensado con arilo o heteroarilo como agentes anti - inflamatorios y analgesicos.
PL373970A1 (en) * 2002-02-08 2005-09-19 Bristol-Myers Squibb Company (oxime)carbamoyl fatty acid amide hydrolase inhibitors
DE10252650A1 (de) * 2002-11-11 2004-05-27 Grünenthal GmbH Cyclohexyl-Harnstoff-Derivate

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CN1878750B (zh) 2011-04-20
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AU2004277436A1 (en) 2005-04-14
CA2539849A1 (fr) 2005-04-14
KR20110093928A (ko) 2011-08-18
AU2011201012B2 (en) 2011-12-15
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