RO93388B - Procedeu pentru prepararea unor derivati de aminoalcooli - Google Patents
Procedeu pentru prepararea unor derivati de aminoalcooliInfo
- Publication number
- RO93388B RO93388B RO120221A RO12022185A RO93388B RO 93388 B RO93388 B RO 93388B RO 120221 A RO120221 A RO 120221A RO 12022185 A RO12022185 A RO 12022185A RO 93388 B RO93388 B RO 93388B
- Authority
- RO
- Romania
- Prior art keywords
- general formula
- compound
- alkyl radical
- atom
- radical
- Prior art date
Links
- -1 amine alcohol derivatives Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 230000000144 pharmacologic effect Effects 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001414 amino alcohols Chemical class 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59203623A JPS6183147A (ja) | 1984-09-28 | 1984-09-28 | 新規なアミノアルコール誘導体およびその製造法並びにそれを有効成分とするグルタミン酸遮断剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO93388A RO93388A (ro) | 1987-12-31 |
| RO93388B true RO93388B (ro) | 1988-01-03 |
Family
ID=16477107
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO120221A RO93388B (ro) | 1984-09-28 | 1985-09-27 | Procedeu pentru prepararea unor derivati de aminoalcooli |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0177245B1 (d) |
| JP (1) | JPS6183147A (d) |
| KR (1) | KR910002671B1 (d) |
| AR (1) | AR242776A1 (d) |
| AT (1) | ATE62480T1 (d) |
| AU (1) | AU578737B2 (d) |
| BR (1) | BR8504879A (d) |
| CA (1) | CA1260467A (d) |
| CS (1) | CS264332B2 (d) |
| DE (1) | DE3582466D1 (d) |
| DK (1) | DK167117B1 (d) |
| ES (1) | ES8706610A1 (d) |
| HU (1) | HU199774B (d) |
| IN (1) | IN162767B (d) |
| MX (1) | MX162733A (d) |
| MY (1) | MY102921A (d) |
| NZ (1) | NZ213628A (d) |
| PH (1) | PH21169A (d) |
| RO (1) | RO93388B (d) |
| SU (1) | SU1433409A3 (d) |
| ZA (1) | ZA857449B (d) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5070196A (en) * | 1986-02-01 | 1991-12-03 | Nippon Chemiphar Co., Ltd. | Alkylenediamine derivatives |
| DE3789395T2 (de) * | 1986-02-01 | 1994-08-04 | Nippon Chemiphar Co | Alkylendiamin-Derivate. |
| JPH0314562A (ja) * | 1988-04-11 | 1991-01-23 | Nippon Chemiphar Co Ltd | 新規なアルキレンジアミン誘導体およびグルタミン酸遮断剤 |
| WO1992022279A2 (en) * | 1991-06-06 | 1992-12-23 | G.D. Searle & Co. | N-[arylethyl]-n-alkyl-2-(1-pyrrolidinyl)ethylamine derivatives for cns disorders |
| IT1271623B (it) * | 1994-03-21 | 1997-06-04 | Lifegroup Spa | N-acilderivati di aminoalcoli con acidi monocarbossilici e bicarbossilici con attivita' neuroprotettiva nelle patologie neurologiche correlate ad eccitotossicita' |
| CA2231013A1 (en) * | 1997-04-30 | 1998-10-30 | Eli Lilly And Company | Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceuticals |
| US20040127733A1 (en) | 2002-10-31 | 2004-07-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New beta-agonists, processes for preparing them and their use as pharmaceutical compositions |
| DE10251170A1 (de) * | 2002-10-31 | 2004-05-13 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| DE102004021779A1 (de) | 2004-04-30 | 2005-11-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| DE102005052127A1 (de) | 2005-10-28 | 2007-05-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue indol-haltige Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2600217A (en) * | 1948-06-22 | 1952-06-10 | American Cyanamid Co | Diaryl-hydroxyalkyl-diamino compounds and preparation thereof |
| US3092636A (en) * | 1959-10-21 | 1963-06-04 | Upjohn Co | Alpha-[2-(1-alkyleneimino) ethylamino]-alkanophenones and the corresponding alcohols |
| GB1200886A (en) * | 1966-09-23 | 1970-08-05 | Allen & Hanburys Ltd | Phenylaminoethanol derivatives |
| US3517000A (en) * | 1968-08-08 | 1970-06-23 | American Home Prod | Alpha-aminomethyl benzyl alcohols |
| FR2370472A2 (fr) * | 1976-11-10 | 1978-06-09 | Continental Pharma | Amino-alcool heterocyclique, son sel et son procede de preparation |
| JPS6183170A (ja) * | 1984-09-28 | 1986-04-26 | Nippon Chemiphar Co Ltd | 新規な１，３−オキサゾリジン−２−オン誘導体およびその製造法 |
-
1984
- 1984-09-28 JP JP59203623A patent/JPS6183147A/ja active Granted
-
1985
- 1985-09-17 IN IN724/MAS/85A patent/IN162767B/en unknown
- 1985-09-23 AU AU47689/85A patent/AU578737B2/en not_active Ceased
- 1985-09-24 EP EP85306767A patent/EP0177245B1/en not_active Expired - Lifetime
- 1985-09-24 CA CA000491405A patent/CA1260467A/en not_active Expired
- 1985-09-24 AT AT85306767T patent/ATE62480T1/de active
- 1985-09-24 DE DE8585306767T patent/DE3582466D1/de not_active Expired - Fee Related
- 1985-09-25 ES ES547283A patent/ES8706610A1/es not_active Expired
- 1985-09-26 ZA ZA857449A patent/ZA857449B/xx unknown
- 1985-09-26 CS CS856904A patent/CS264332B2/cs unknown
- 1985-09-26 KR KR1019850007117A patent/KR910002671B1/ko not_active Expired
- 1985-09-27 SU SU853957801A patent/SU1433409A3/ru active
- 1985-09-27 DK DK439285A patent/DK167117B1/da not_active IP Right Cessation
- 1985-09-27 NZ NZ213628A patent/NZ213628A/xx unknown
- 1985-09-27 HU HU853744A patent/HU199774B/hu not_active IP Right Cessation
- 1985-09-27 PH PH32860A patent/PH21169A/en unknown
- 1985-09-27 AR AR85301762A patent/AR242776A1/es active
- 1985-09-27 RO RO120221A patent/RO93388B/ro unknown
- 1985-09-30 BR BR8504879A patent/BR8504879A/pt not_active IP Right Cessation
- 1985-10-01 MX MX64A patent/MX162733A/es unknown
-
1987
- 1987-09-29 MY MYPI87002216A patent/MY102921A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK167117B1 (da) | 1993-08-30 |
| HU199774B (en) | 1990-03-28 |
| JPS6183147A (ja) | 1986-04-26 |
| DK439285A (da) | 1986-03-29 |
| ZA857449B (en) | 1986-06-25 |
| HUT40613A (en) | 1987-01-28 |
| DE3582466D1 (de) | 1991-05-16 |
| AU578737B2 (en) | 1988-11-03 |
| CS690485A2 (en) | 1988-11-15 |
| PH21169A (en) | 1987-08-07 |
| ES547283A0 (es) | 1987-07-01 |
| CS264332B2 (en) | 1989-07-12 |
| MY102921A (en) | 1993-03-31 |
| AU4768985A (en) | 1986-04-10 |
| EP0177245B1 (en) | 1991-04-10 |
| CA1260467A (en) | 1989-09-26 |
| EP0177245A2 (en) | 1986-04-09 |
| KR910002671B1 (ko) | 1991-05-03 |
| JPH0517900B2 (d) | 1993-03-10 |
| KR860002450A (ko) | 1986-04-26 |
| SU1433409A3 (ru) | 1988-10-23 |
| RO93388A (ro) | 1987-12-31 |
| AR242776A1 (es) | 1993-05-31 |
| ATE62480T1 (de) | 1991-04-15 |
| MX162733A (es) | 1991-06-24 |
| NZ213628A (en) | 1989-03-29 |
| BR8504879A (pt) | 1986-07-22 |
| DK439285D0 (da) | 1985-09-27 |
| EP0177245A3 (en) | 1987-07-01 |
| IN162767B (d) | 1988-07-09 |
| ES8706610A1 (es) | 1987-07-01 |
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