PT90696A - Processo de preparacao de novos compostos tri-iodobenzenicos nao ionicos e de produtos de contraste que os contem - Google Patents

Processo de preparacao de novos compostos tri-iodobenzenicos nao ionicos e de produtos de contraste que os contem

Info

Publication number
PT90696A
PT90696A PT90696A PT9069689A PT90696A PT 90696 A PT90696 A PT 90696A PT 90696 A PT90696 A PT 90696A PT 9069689 A PT9069689 A PT 9069689A PT 90696 A PT90696 A PT 90696A
Authority
PT
Portugal
Prior art keywords
ionic
contain
preparation process
new non
compounds
Prior art date
Application number
PT90696A
Other languages
English (en)
Other versions
PT90696B (pt
Inventor
Michel Schaefer
Maryse Dugast-Zrihen
Michel Guillemot
Didier Doucet
Dominique Meyer
Original Assignee
Guerbet Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8807369A external-priority patent/FR2632304B1/fr
Priority claimed from FR8900762A external-priority patent/FR2643077B1/fr
Application filed by Guerbet Sa filed Critical Guerbet Sa
Publication of PT90696A publication Critical patent/PT90696A/pt
Publication of PT90696B publication Critical patent/PT90696B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21H—OBTAINING ENERGY FROM RADIOACTIVE SOURCES; APPLICATIONS OF RADIATION FROM RADIOACTIVE SOURCES, NOT OTHERWISE PROVIDED FOR; UTILISING COSMIC RADIATION
    • G21H5/00—Applications of radiation from radioactive sources or arrangements therefor, not otherwise provided for 
    • G21H5/02—Applications of radiation from radioactive sources or arrangements therefor, not otherwise provided for  as tracers

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT90696A 1988-06-02 1989-06-01 Processo de preparacao de novos compostos tri-iodobenzenicos nao ionicos e de produtos de contraste que os contem PT90696B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8807369A FR2632304B1 (fr) 1988-06-02 1988-06-02 Composes triodobenzeniques non ioniques, leur procede de preparation et produits de contraste les contenant
FR8900762A FR2643077B1 (fr) 1989-01-23 1989-01-23 Nouveaux composes non ioniques iodes et produits de contraste les contenant

Publications (2)

Publication Number Publication Date
PT90696A true PT90696A (pt) 1989-12-29
PT90696B PT90696B (pt) 1995-03-01

Family

ID=26226693

Family Applications (1)

Application Number Title Priority Date Filing Date
PT90696A PT90696B (pt) 1988-06-02 1989-06-01 Processo de preparacao de novos compostos tri-iodobenzenicos nao ionicos e de produtos de contraste que os contem

Country Status (25)

Country Link
EP (1) EP0357467B1 (pt)
JP (1) JPH07100684B2 (pt)
KR (1) KR0148358B1 (pt)
CN (1) CN1021440C (pt)
AT (1) ATE98220T1 (pt)
AU (1) AU617810B2 (pt)
CA (1) CA1339665C (pt)
CZ (1) CZ277984B6 (pt)
DE (1) DE68911237T2 (pt)
DK (1) DK175034B1 (pt)
DZ (1) DZ1341A1 (pt)
EG (1) EG19008A (pt)
ES (1) ES2060800T3 (pt)
FI (1) FI102745B (pt)
GE (1) GEP19960460B (pt)
HR (1) HRP920498B1 (pt)
HU (1) HU201732B (pt)
IL (1) IL90326A (pt)
LV (1) LV10234B (pt)
MA (1) MA21565A1 (pt)
NO (1) NO177461C (pt)
PT (1) PT90696B (pt)
RU (1) RU1833365C (pt)
SI (1) SI8911042A (pt)
YU (1) YU48318B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2656865B1 (fr) * 1990-01-05 1993-03-26 Guerbet Sa Compose non ionique iode, son procede de preparation et produit de contraste le contenant.
FR2673180B1 (fr) * 1991-02-25 1994-03-04 Guerbet Sa Nouveaux composes non ioniques poly-iodes, procede de preparation, produit de contraste les contenant.
DE4109169A1 (de) * 1991-03-20 1992-09-24 Koehler Chemie Dr Franz Wasserloesliche nicht ionische roentgenkontrastmittel sowie mittel und verfahren zu ihrer herstellung
FR2695125B1 (fr) * 1992-08-25 1994-12-23 Guerbet Sa Nouveaux composés poly-iodés, procédé de préparation, produit de contraste les contenant.
US6310243B1 (en) * 1994-09-23 2001-10-30 Nycomed Imaging As Iodinated x-ray contrast media
PT101720A (pt) * 1995-06-08 1997-01-31 Hovione Sociedade Quimica S A Processo para a purificacao e cristalizacao de iopamidol
US5705692A (en) * 1996-09-27 1998-01-06 Abbott Laboratories Process for the preparation of iohexol
CN110903275A (zh) * 2018-09-14 2020-03-24 苏州科伦药物研究有限公司 制备碘比醇的方法、其中间体及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2909439A1 (de) * 1979-03-08 1980-09-18 Schering Ag Neue nichtionische roentgenkontrastmittel
US4396598A (en) * 1982-01-11 1983-08-02 Mallinckrodt, Inc. Triiodoisophthalamide X-ray contrast agent
DE3429949A1 (de) * 1984-08-10 1986-02-20 Schering AG, 1000 Berlin und 4709 Bergkamen Neue nicht -ionische 2,4,6-trijod-isophthalsaeure-bis-amide, verfahren zu ihrer herstellung und ihre verwendung als roentgenkontrastmittel
KR960016747B1 (ko) * 1987-05-22 1996-12-20 브라코 인터내셔날 비. 브이 5-아실아미노-2,4,6-트리요오도-또는 트리브로모-벤조산 유도체의 제조 방법
FR2632304B1 (fr) * 1988-06-02 1991-05-17 Guerbert Sa Composes triodobenzeniques non ioniques, leur procede de preparation et produits de contraste les contenant

Also Published As

Publication number Publication date
FI892681A0 (fi) 1989-06-01
NO177461C (no) 1995-09-20
CA1339665C (en) 1998-02-10
NO177461B (no) 1995-06-12
GEP19960460B (en) 1996-07-10
DK175034B1 (da) 2004-05-03
JPH07100684B2 (ja) 1995-11-01
LV10234A (lv) 1994-10-20
EP0357467B1 (fr) 1993-12-08
KR0148358B1 (ko) 1998-08-17
FI892681A (fi) 1989-12-03
NO892189L (no) 1989-12-04
SI8911042A (en) 1997-10-31
RU1833365C (ru) 1993-08-07
FI102745B1 (fi) 1999-02-15
AU617810B2 (en) 1991-12-05
CN1021440C (zh) 1993-06-30
EG19008A (en) 1994-06-30
IL90326A0 (en) 1989-12-15
CZ329189A3 (en) 1993-04-14
MA21565A1 (fr) 1989-12-31
DK259589A (da) 1989-12-03
KR900000329A (ko) 1990-01-30
YU48318B (sh) 1998-05-15
HRP920498B1 (en) 1998-06-30
PT90696B (pt) 1995-03-01
FI102745B (fi) 1999-02-15
DE68911237D1 (de) 1994-01-20
EP0357467A1 (fr) 1990-03-07
CN1038094A (zh) 1989-12-20
NO892189D0 (no) 1989-05-31
LV10234B (en) 1995-04-20
CZ277984B6 (en) 1993-07-14
HU201732B (en) 1990-12-28
DZ1341A1 (fr) 2004-09-13
YU104289A (en) 1991-04-30
DE68911237T2 (de) 1994-05-11
IL90326A (en) 1993-05-13
ATE98220T1 (de) 1993-12-15
JPH0225456A (ja) 1990-01-26
HUT50107A (en) 1989-12-28
DK259589D0 (da) 1989-05-26
ES2060800T3 (es) 1994-12-01
HRP920498A2 (hr) 1994-04-30
AU3523589A (en) 1989-12-07

Similar Documents

Publication Publication Date Title
PT98710A (pt) Processo de preparacao de compostos de indolilo substituidos e de composicoes farmaceuticas que os contem
PT97254A (pt) Processo para a preparacao de azoles substituido e de composicoes farmaceuticas que os contem
PT96394A (pt) Processo para a preparacao de novos derivados do acido a-nor-esteroide-3-carboxilico e de composicoes farmaceuticas que os contem
PT97866A (pt) Processo para a preparacao de uma composicao de um fluxo vitreo
BR8203771A (pt) Processo para preparacao de um composto e composicoes detergentes contendo o mesmo
PT99545A (pt) Processo de preparacao de compostos inibidores da protease retroviral dos seus intermediarios e de composicoes farmaceuticas que os contem
ES2052736T3 (es) Fibra optica con aditivo fluorescente.
JPS5564571A (en) Novel 1*44dihydropyridine compound having substituted ester group
BR8004404A (pt) Composicao, processo destinado a preparacao de uma peca de fundicao e produto otico claro
BR7904505A (pt) Solucao de aclarador de estilbeno e processo para o aclaramento otico de materiais fibrosos
BR8004478A (pt) Misturas de aclaradores oticos e sua aplicacao
PT90696A (pt) Processo de preparacao de novos compostos tri-iodobenzenicos nao ionicos e de produtos de contraste que os contem
PT94685A (pt) Processo para a preparacao de 2-imidazolinas substituidas e de composicoes farmaceuticas que as contem
PT98268A (pt) Processo para a preparacao de indano-pirrolidino-carbamatos
PT95737A (pt) Processo para a preparacao de intermediarios e para a sintss de n-(2-hidroxietil)-2-hidroximetil-3,4,5-tri-hidroxipiperidinas
PT89303A (pt) Processo para a preparacao de tienotriciclos e de composicoes farmaceuticas que os contem
PT80123B (pt) Processo para a preparacao de novos antibioticos e de composicoes que os contem uteis para o tratamento de infeccoes provocadas por protozoarios
BR8906421A (pt) Processo para preparacao de monopersulfato de piridina-3-acido peroxicarboxilico
BR7902917A (pt) Compostos organicos,processo para sua preparacao,composicao de aclaramento otico e emprego
SE8700566L (sv) Tetracykliska kinazolinoner
BR8303239A (pt) Processo para preparar um derivado de organofosfato, processo para preparar um derivado de fenol utilizavel no mesmo, composicao pesticida e aplicacao do derivado citado no inicio
ES2060854T3 (es) Procedimiento para la preparacion de acido 2-mercapto-4-metil-1,3-tiazol-5-il-acetico y sus esteres.
BR9106876A (pt) Processo aperfeicoado para aumentar o rendimento de um oxo-alcool
ES2071723T3 (es) Bencilseleniobenzoamidas de aminopiridinas y picolilaminas.
FI960929A (fi) Välituotteena käyttökelpoiset indolonijohdannaiset

Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19940805

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20070205