HRP920498B1 - Process for the preparation of new triiodobenzene compounds with nonionic iodine and contrast products containing them - Google Patents
Process for the preparation of new triiodobenzene compounds with nonionic iodine and contrast products containing themInfo
- Publication number
- HRP920498B1 HRP920498B1 HRP-1042/89A HRP920498A HRP920498B1 HR P920498 B1 HRP920498 B1 HR P920498B1 HR P920498 A HRP920498 A HR P920498A HR P920498 B1 HRP920498 B1 HR P920498B1
- Authority
- HR
- Croatia
- Prior art keywords
- new
- preparation
- products containing
- compounds
- contrast products
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21H—OBTAINING ENERGY FROM RADIOACTIVE SOURCES; APPLICATIONS OF RADIATION FROM RADIOACTIVE SOURCES, NOT OTHERWISE PROVIDED FOR; UTILISING COSMIC RADIATION
- G21H5/00—Applications of radiation from radioactive sources or arrangements therefor, not otherwise provided for
- G21H5/02—Applications of radiation from radioactive sources or arrangements therefor, not otherwise provided for as tracers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- High Energy & Nuclear Physics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention relates to new nonionic compounds of formula <IMAGE> These compounds can be employed as contrast agents.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8807369A FR2632304B1 (en) | 1988-06-02 | 1988-06-02 | NON-IONIC TRIODOBENZENIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND CONTRAST PRODUCTS CONTAINING THEM |
FR8900762A FR2643077B1 (en) | 1989-01-23 | 1989-01-23 | NOVEL IODIC NON-IONIC COMPOUNDS AND CONTRAST PRODUCTS CONTAINING THEM |
YU104289A YU48318B (en) | 1988-06-02 | 1989-05-22 | PROCEDURE FOR OBTAINING NEW TRIODOBENZEN UNITS AND THE CONTRAST AGENCY CONTAINING THEM |
Publications (2)
Publication Number | Publication Date |
---|---|
HRP920498A2 HRP920498A2 (en) | 1994-04-30 |
HRP920498B1 true HRP920498B1 (en) | 1998-06-30 |
Family
ID=26226693
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HRP-1042/89A HRP920498B1 (en) | 1988-06-02 | 1992-09-25 | Process for the preparation of new triiodobenzene compounds with nonionic iodine and contrast products containing them |
Country Status (25)
Country | Link |
---|---|
EP (1) | EP0357467B1 (en) |
JP (1) | JPH07100684B2 (en) |
KR (1) | KR0148358B1 (en) |
CN (1) | CN1021440C (en) |
AT (1) | ATE98220T1 (en) |
AU (1) | AU617810B2 (en) |
CA (1) | CA1339665C (en) |
CZ (1) | CZ277984B6 (en) |
DE (1) | DE68911237T2 (en) |
DK (1) | DK175034B1 (en) |
DZ (1) | DZ1341A1 (en) |
EG (1) | EG19008A (en) |
ES (1) | ES2060800T3 (en) |
FI (1) | FI102745B (en) |
GE (1) | GEP19960460B (en) |
HR (1) | HRP920498B1 (en) |
HU (1) | HU201732B (en) |
IL (1) | IL90326A (en) |
LV (1) | LV10234B (en) |
MA (1) | MA21565A1 (en) |
NO (1) | NO177461C (en) |
PT (1) | PT90696B (en) |
RU (1) | RU1833365C (en) |
SI (1) | SI8911042A (en) |
YU (1) | YU48318B (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2656865B1 (en) * | 1990-01-05 | 1993-03-26 | Guerbet Sa | NON-IONIC IODINE COMPOUND, PROCESS FOR PREPARING THE SAME, AND CONTRAST PRODUCT CONTAINING THE SAME. |
FR2673180B1 (en) * | 1991-02-25 | 1994-03-04 | Guerbet Sa | NOVEL POLY-IODIC NON-IONIC COMPOUNDS, PREPARATION METHOD, CONTRAST PRODUCT CONTAINING THE SAME. |
DE4109169A1 (en) * | 1991-03-20 | 1992-09-24 | Koehler Chemie Dr Franz | WATER-SOLUBLE NON-IONIC X-RAY CONTRASTING AGENTS AND AGENTS AND METHOD FOR THE PRODUCTION THEREOF |
FR2695125B1 (en) * | 1992-08-25 | 1994-12-23 | Guerbet Sa | New polyiodinated compounds, preparation process, contrast medium containing them. |
US6310243B1 (en) * | 1994-09-23 | 2001-10-30 | Nycomed Imaging As | Iodinated x-ray contrast media |
PT101720A (en) * | 1995-06-08 | 1997-01-31 | Hovione Sociedade Quimica S A | PROCESS FOR THE PURIFICATION AND CRYSTALLIZATION OF IOPAMIDOL |
US5705692A (en) * | 1996-09-27 | 1998-01-06 | Abbott Laboratories | Process for the preparation of iohexol |
CN110903275A (en) * | 2018-09-14 | 2020-03-24 | 苏州科伦药物研究有限公司 | Process for producing iobitridol, intermediate therefor, and process for producing the same |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2909439A1 (en) * | 1979-03-08 | 1980-09-18 | Schering Ag | NEW NON-ionic x-ray contrast agents |
US4396598A (en) * | 1982-01-11 | 1983-08-02 | Mallinckrodt, Inc. | Triiodoisophthalamide X-ray contrast agent |
DE3429949A1 (en) * | 1984-08-10 | 1986-02-20 | Schering AG, 1000 Berlin und 4709 Bergkamen | Novel non-ionic 2,4,6-triiodoisophthalic acid bisamides, process for the preparation thereof and the use thereof as X-ray contrast media |
KR960016747B1 (en) * | 1987-05-22 | 1996-12-20 | 브라코 인터내셔날 비. 브이 | Preparation of 5-acylamino-2,4,6 triiodo or tribromo benzoic acid derivatives |
FR2632304B1 (en) * | 1988-06-02 | 1991-05-17 | Guerbert Sa | NON-IONIC TRIODOBENZENIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND CONTRAST PRODUCTS CONTAINING THEM |
-
1989
- 1989-05-17 IL IL90326A patent/IL90326A/en not_active IP Right Cessation
- 1989-05-21 DZ DZ890079A patent/DZ1341A1/en active
- 1989-05-22 YU YU104289A patent/YU48318B/en unknown
- 1989-05-22 SI SI8911042A patent/SI8911042A/en not_active IP Right Cessation
- 1989-05-23 KR KR1019890006875A patent/KR0148358B1/en not_active IP Right Cessation
- 1989-05-26 AU AU35235/89A patent/AU617810B2/en not_active Ceased
- 1989-05-26 DK DK198902595A patent/DK175034B1/en not_active IP Right Cessation
- 1989-05-30 RU SU894614183A patent/RU1833365C/en not_active IP Right Cessation
- 1989-05-31 NO NO892189A patent/NO177461C/en not_active Application Discontinuation
- 1989-05-31 CZ CS893291A patent/CZ277984B6/en not_active IP Right Cessation
- 1989-06-01 AT AT89401509T patent/ATE98220T1/en not_active IP Right Cessation
- 1989-06-01 PT PT90696A patent/PT90696B/en not_active IP Right Cessation
- 1989-06-01 JP JP1140222A patent/JPH07100684B2/en not_active Expired - Fee Related
- 1989-06-01 EG EG26789A patent/EG19008A/en active
- 1989-06-01 ES ES89401509T patent/ES2060800T3/en not_active Expired - Lifetime
- 1989-06-01 CA CA000601412A patent/CA1339665C/en not_active Expired - Fee Related
- 1989-06-01 EP EP89401509A patent/EP0357467B1/en not_active Expired - Lifetime
- 1989-06-01 CN CN89103735A patent/CN1021440C/en not_active Expired - Lifetime
- 1989-06-01 DE DE89401509T patent/DE68911237T2/en not_active Expired - Fee Related
- 1989-06-01 FI FI892681A patent/FI102745B/en not_active IP Right Cessation
- 1989-06-01 MA MA21817A patent/MA21565A1/en unknown
- 1989-06-02 HU HU892826A patent/HU201732B/en not_active IP Right Cessation
-
1992
- 1992-09-25 HR HRP-1042/89A patent/HRP920498B1/en not_active IP Right Cessation
-
1993
- 1993-03-11 GE GEAP1993599A patent/GEP19960460B/en unknown
- 1993-05-25 LV LVP-93-404A patent/LV10234B/en unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A1OB | Publication of a patent application | ||
AIPI | Request for the grant of a patent on the basis of a substantive examination of a patent application | ||
B1PR | Patent granted | ||
ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20080507 Year of fee payment: 20 |
|
PB20 | Patent expired after termination of 20 years |
Effective date: 20090523 |