PT95737A - Processo para a preparacao de intermediarios e para a sintss de n-(2-hidroxietil)-2-hidroximetil-3,4,5-tri-hidroxipiperidinas - Google Patents

Processo para a preparacao de intermediarios e para a sintss de n-(2-hidroxietil)-2-hidroximetil-3,4,5-tri-hidroxipiperidinas

Info

Publication number
PT95737A
PT95737A PT95737A PT9573790A PT95737A PT 95737 A PT95737 A PT 95737A PT 95737 A PT95737 A PT 95737A PT 9573790 A PT9573790 A PT 9573790A PT 95737 A PT95737 A PT 95737A
Authority
PT
Portugal
Prior art keywords
hydroxymethyl
hydroxyethyl
preparation
sintss
hydroxipyphidides
Prior art date
Application number
PT95737A
Other languages
English (en)
Other versions
PT95737B (pt
Inventor
Werner Hinsken
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of PT95737A publication Critical patent/PT95737A/pt
Publication of PT95737B publication Critical patent/PT95737B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/46Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Enzymes And Modification Thereof (AREA)
PT95737A 1989-11-01 1990-10-30 Processo para a preparacao de intermediarios e para a sintss de n-(2-hidroxietil)-2-hidroximetil-3,4,5-tri-hidroxipiperidinas PT95737B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3936295A DE3936295A1 (de) 1989-11-01 1989-11-01 Verfahren zur herstellung von zwischenprodukten und zur synthese von n-(2-hydroxyethyl)-2-hydroxymethyl-3,4,5-trihydroxypiperidine

Publications (2)

Publication Number Publication Date
PT95737A true PT95737A (pt) 1991-09-13
PT95737B PT95737B (pt) 1997-11-28

Family

ID=6392610

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95737A PT95737B (pt) 1989-11-01 1990-10-30 Processo para a preparacao de intermediarios e para a sintss de n-(2-hidroxietil)-2-hidroximetil-3,4,5-tri-hidroxipiperidinas

Country Status (16)

Country Link
US (1) US5071990A (pt)
EP (1) EP0425929B1 (pt)
JP (1) JP2858927B2 (pt)
KR (1) KR0169977B1 (pt)
AT (1) ATE131155T1 (pt)
CA (1) CA2028909C (pt)
DE (2) DE3936295A1 (pt)
DK (1) DK0425929T3 (pt)
ES (1) ES2082815T3 (pt)
FI (1) FI93443C (pt)
GR (1) GR3018765T3 (pt)
HU (1) HU205946B (pt)
IE (1) IE70059B1 (pt)
IL (1) IL96149A (pt)
PT (1) PT95737B (pt)
ZA (1) ZA908723B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5252587A (en) * 1990-04-27 1993-10-12 Merrell Dow Pharmaceuticals, Inc. N-derivatives of 1-deoxy nojirimycin
US5536732A (en) * 1990-04-27 1996-07-16 Merrell Pharmaceuticals Inc. N-derivatives of 1-deoxy nojirimycin
PT2027137E (pt) * 2005-06-08 2015-06-09 Amicus Therapeutics Inc Purificação de imino e amino-açúcares
BRPI0613221A2 (pt) * 2005-06-08 2010-12-28 Amicus Therapeutics Inc furanose cristalina e método para produzir uma furanose cristalina
BRPI0613224A2 (pt) * 2005-06-08 2010-12-28 Amicus Therapeutics Inc método para estabilizar um açúcar triflatado, método para aumentar o rendimento da reação de um produto de açúcar e composição de açúcar triflatado estabilizada
CN103980290B (zh) * 2013-12-06 2016-08-17 华东理工大学 具有杀虫活性的吗啉并环类化合物、及其制备和用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3759929A (en) * 1970-11-02 1973-09-18 Basf Ag Manufacture of {62 -hydroxy carbonyl compounds and/or {60 -unsaturated carbonyl compounds
DE2758025A1 (de) * 1977-12-24 1979-07-12 Bayer Ag Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung
NO154918C (no) * 1977-08-27 1987-01-14 Bayer Ag Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.
JPS54106477A (en) * 1978-02-03 1979-08-21 Nippon Shinyaku Co Ltd Moranoline derivative
DE2922760A1 (de) * 1979-06-05 1980-12-11 Bayer Ag Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel sowie in der tierernaehrung
JPS6011902B2 (ja) * 1979-12-27 1985-03-28 日本新薬株式会社 モラノリンの誘導体
DE3024901A1 (de) * 1980-07-01 1982-01-28 Bayer Ag, 5090 Leverkusen Herbizide mittel auf basis von piperidin-derivaten
DE3038901A1 (de) * 1980-10-15 1982-05-06 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von n-substituierten derivaten des 1-desoxynojirimycins
DE3049446A1 (de) * 1980-12-30 1982-07-29 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von 1,5-didesoxy-1,5-imino-d-glucitol und dessen n-derivaten
DE3611841A1 (de) * 1986-04-09 1987-10-15 Bayer Ag Verfahren zur herstellung von 1-desoxynojirimycin und dessen n-derivaten
JPS62267292A (ja) * 1986-05-14 1987-11-19 Nippon Shinyaku Co Ltd モラノリン誘導体の製法
DE3814549A1 (de) * 1987-10-30 1989-05-18 Bayer Ag N-substituierte derivate von 1-desoxynojirimycin und 1-desoxymannonojirimycin, verfahren zu deren herstellung und deren verwendung in arzneimitteln
EP0344383A1 (en) * 1988-06-02 1989-12-06 Merrell Dow Pharmaceuticals Inc. Novel alpha-Glucosidase inhibitors
DE3906463A1 (de) * 1989-03-01 1990-09-06 Bayer Ag Verfahren zur herstellung von n-hydroxyalkyl-substituierten derivaten von 3,4,5-trihydroxypiperidinen

Also Published As

Publication number Publication date
DE3936295A1 (de) 1991-05-02
GR3018765T3 (en) 1996-04-30
HUT55404A (en) 1991-05-28
DE59009951D1 (de) 1996-01-18
KR910009661A (ko) 1991-06-28
CA2028909C (en) 2002-01-22
ES2082815T3 (es) 1996-04-01
HU205946B (en) 1992-07-28
US5071990A (en) 1991-12-10
JPH03153666A (ja) 1991-07-01
FI93443C (fi) 1995-04-10
EP0425929A1 (de) 1991-05-08
PT95737B (pt) 1997-11-28
DK0425929T3 (da) 1996-04-15
ATE131155T1 (de) 1995-12-15
IE903924A1 (en) 1991-05-08
FI905353A0 (fi) 1990-10-30
IL96149A (en) 1995-05-26
ZA908723B (en) 1991-08-28
CA2028909A1 (en) 1991-05-02
KR0169977B1 (ko) 1999-02-18
IL96149A0 (en) 1991-07-18
FI93443B (fi) 1994-12-30
EP0425929B1 (de) 1995-12-06
IE70059B1 (en) 1996-10-16
JP2858927B2 (ja) 1999-02-17

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19910402

FG3A Patent granted, date of granting

Effective date: 19970828

PC3A Transfer or assignment

Free format text: BAYER HEALTHCARE AG DE

Effective date: 20040824

PC4A Transfer of assignment

Owner name: BAYER SCHERING PHARMA AG, DE

Effective date: 20090310

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: MAXIMUM VALIDITY LIMIT REACHED

Effective date: 20120828