PT545511E - Processo para a preparacao de tetraazamacrociclos mono-n-substituidos - Google Patents
Processo para a preparacao de tetraazamacrociclos mono-n-substituidosInfo
- Publication number
- PT545511E PT545511E PT92250351T PT92250351T PT545511E PT 545511 E PT545511 E PT 545511E PT 92250351 T PT92250351 T PT 92250351T PT 92250351 T PT92250351 T PT 92250351T PT 545511 E PT545511 E PT 545511E
- Authority
- PT
- Portugal
- Prior art keywords
- mono
- preparation
- tetraazamacrocycles
- substituted
- substituted tetraazamacrocycles
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4140779A DE4140779A1 (de) | 1991-12-06 | 1991-12-06 | Verfahren zur herstellung von mono-n-substituierten tetraazamakrocyclen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT545511E true PT545511E (pt) | 2002-10-31 |
Family
ID=6446767
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT92250351T PT545511E (pt) | 1991-12-06 | 1992-12-03 | Processo para a preparacao de tetraazamacrociclos mono-n-substituidos |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0545511B1 (pt) |
| JP (1) | JP3471836B2 (pt) |
| AT (1) | ATE218131T1 (pt) |
| CA (1) | CA2084582C (pt) |
| CZ (1) | CZ290232B6 (pt) |
| DE (2) | DE4140779A1 (pt) |
| DK (1) | DK0545511T3 (pt) |
| ES (1) | ES2176183T3 (pt) |
| HU (2) | HU9203860D0 (pt) |
| IL (1) | IL103996A (pt) |
| NO (5) | NO303496B1 (pt) |
| PT (1) | PT545511E (pt) |
| SK (1) | SK282386B6 (pt) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4237943C2 (de) * | 1992-11-06 | 1997-10-23 | Schering Ag | Verfahren zur Herstellung von Metallkomplexen der N-beta-Hydroxyalkyl-tri-N-carboxyalkyl-1,4,7,10-tetraazacyclododecan- und N-beta-Hydroxyalkyl-tri-N-carboxyalkyl-1,4,8,11-tetraazacyclotetradecan-Derivate |
| DE4317588C2 (de) * | 1993-05-24 | 1998-04-16 | Schering Ag | Fluorhaltige makrocyclische Metallkomplexe, Verfahren zu ihrer Herstellung, sowie ihre Verwendung |
| DE4318369C1 (de) * | 1993-05-28 | 1995-02-09 | Schering Ag | Verwendung von makrocyclischen Metallkomplexen als Temperatursonden |
| DE4340809C2 (de) * | 1993-11-24 | 2000-08-03 | Schering Ag | 1.4,7,10-Tetraazacyclododecan-Derivate, diese enthaltende pharmazeutische Mittel und Verfahren zu deren Herstellung |
| FR2725449B1 (fr) * | 1994-10-05 | 1996-12-27 | Air Liquide | Derives de polyazacycloalcanes, leurs complexes metalliques et produits pharmaceutiques incorporant ces complexes |
| DE19724186C2 (de) * | 1997-06-02 | 2002-07-18 | Schering Ag | Verfahren zur Mono- und 1,7-Bis-N-ß-Hydroxyalkylierung von Cyclen und die entsprechenden N-ß-Hydroxyalkyl-1,4,7,10-tetraazacyclododecan-Li-Salz-Komplexe |
| IT1297035B1 (it) * | 1997-12-30 | 1999-08-03 | Bracco Spa | Derivati dell'acido 1,4,7,10-tetraazaciclododecan-1,4-diacetico |
| DE19914101C1 (de) * | 1999-03-22 | 2000-10-12 | Schering Ag | Perfluoralkylamide, ihre Herstellung und ihre Verwendung in der Diagnostik |
| DE10002939C1 (de) * | 2000-01-13 | 2001-09-20 | Schering Ag | Paramagnetische DOTA-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung für die Herstellung von pharmazeutischen Mitteln |
| CN103189057B (zh) * | 2010-08-26 | 2015-02-18 | 崔坤元 | 大环脂类化合物及其应用 |
| RS60001B1 (sr) | 2011-04-21 | 2020-04-30 | Bayer Ip Gmbh | Pripremanje gadobutrola visoke čistoće |
| KR101653064B1 (ko) * | 2014-12-26 | 2016-09-09 | 에스티팜 주식회사 | 가도부트롤의 제조방법 |
| KR102033964B1 (ko) * | 2018-01-19 | 2019-10-18 | 주식회사 엔지켐생명과학 | 가도테리돌 중간체 및 이를 이용한 가도테리돌 제조방법 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0232751B1 (en) * | 1986-01-23 | 1991-09-11 | E.R. Squibb & Sons, Inc. | 1-substituted-4,7,10-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs |
| DE3625417C2 (de) * | 1986-07-28 | 1998-10-08 | Schering Ag | Tetraazacyclododecan-Derivate |
| US4994560A (en) * | 1987-06-24 | 1991-02-19 | The Dow Chemical Company | Functionalized polyamine chelants and radioactive rhodium complexes thereof for conjugation to antibodies |
| FR2644453A1 (fr) * | 1989-03-20 | 1990-09-21 | Centre Nat Rech Scient | Procede de preparation de tetramines cycliques monofonctionnalisees |
| AU6709390A (en) * | 1989-12-22 | 1991-06-27 | E.R. Squibb & Sons, Inc. | 10-(2'-hydroxy-3'-polyoxaalkyl)-1,4,7-tris-carboxymethyl -1,4,7,10-tetraazacyclododecane |
| AU625529B2 (en) * | 1989-12-22 | 1992-07-16 | E.R. Squibb & Sons, Inc. | 10-(2'-hydroxy-3'-alkoxy-1,4,7-triscarboxymethyl-1,4,7,10- tetraazacyclododecanes |
| DE4009119A1 (de) * | 1990-03-19 | 1991-09-26 | Schering Ag | 1,4,7,10-tetraazacyclododecan-butyltriole, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
| DE4035760A1 (de) * | 1990-11-08 | 1992-05-14 | Schering Ag | Mono-n-substituierte 1,4,7,10-tetraazacyclododecan-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
-
1991
- 1991-12-06 DE DE4140779A patent/DE4140779A1/de not_active Withdrawn
-
1992
- 1992-12-03 DK DK92250351T patent/DK0545511T3/da active
- 1992-12-03 AT AT92250351T patent/ATE218131T1/de active
- 1992-12-03 DE DE59209957T patent/DE59209957D1/de not_active Expired - Lifetime
- 1992-12-03 PT PT92250351T patent/PT545511E/pt unknown
- 1992-12-03 ES ES92250351T patent/ES2176183T3/es not_active Expired - Lifetime
- 1992-12-03 EP EP92250351A patent/EP0545511B1/de not_active Expired - Lifetime
- 1992-12-04 HU HU9203860A patent/HU9203860D0/hu unknown
- 1992-12-04 CA CA002084582A patent/CA2084582C/en not_active Expired - Lifetime
- 1992-12-04 NO NO924690A patent/NO303496B1/no not_active IP Right Cessation
- 1992-12-04 SK SK3573-92A patent/SK282386B6/sk not_active IP Right Cessation
- 1992-12-04 HU HU9203860A patent/HU224923B1/hu unknown
- 1992-12-04 CZ CS19923573A patent/CZ290232B6/cs not_active IP Right Cessation
- 1992-12-06 IL IL103996A patent/IL103996A/en not_active IP Right Cessation
- 1992-12-07 JP JP32657092A patent/JP3471836B2/ja not_active Expired - Lifetime
-
1997
- 1997-08-04 NO NO973579A patent/NO303387B1/no not_active IP Right Cessation
- 1997-08-04 NO NO973578A patent/NO303384B1/no not_active IP Right Cessation
- 1997-08-04 NO NO973581A patent/NO303385B1/no not_active IP Right Cessation
- 1997-08-04 NO NO973580A patent/NO303386B1/no not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT97433A (pt) | Processo para a preparacao de sacarose-6-ester | |
| PT545511E (pt) | Processo para a preparacao de tetraazamacrociclos mono-n-substituidos | |
| BR9200627A (pt) | Processo para a preparacao de um composto e composto obtido | |
| DE69007695T2 (de) | Fucosidase-Inhibitoren. | |
| BR9205129A (pt) | Processo para a preparacao de isocianatos puros | |
| BR9301676A (pt) | Processo para a preparacao de 1,1,1,4,4,4-hexafluorbutano e compostos obtidos | |
| BR9400016A (pt) | Processo para preparação de compostos, e compostos | |
| PT98268A (pt) | Processo para a preparacao de indano-pirrolidino-carbamatos | |
| BR9100447A (pt) | Processo para a floculacao de um caldo aquoso de enzima | |
| BR9306316A (pt) | Processo para a preparação de hexafluorclorobuteneno | |
| BR9205680A (pt) | Processo para a preparaçao de 3'-aminopropil-2-sulfatoetilsulfona | |
| MX9302878A (es) | Procedimiento para la preparacion de un diaminodiol substituido. | |
| ITMI910319A0 (it) | Processo di dealogenazione di 1,3-diossolani | |
| ES2089176T3 (es) | Procedimiento para la preparacion de carboditioatos de piperidina fluorometil-sustituidos. | |
| PT101158A (pt) | Processo para a preparacao de novos derivados de benzofuranilimidazol | |
| BR9404139A (pt) | Processo aperfeiçoado para a preparação de compostos de fórmula (I) ou fórmula (II) | |
| PT96088A (pt) | Processo para a preparacao de compostos moluscicidas 2,4,5-tribomopirrole-3-carbonitrilo | |
| BR9306348A (pt) | Processo para a preparação de hexafluorbutano | |
| FI960526A (fi) | Menetelmä kumeenihydroperoksin valmistamiseksi | |
| BR8905847A (pt) | Processo para a preparacao de compostos e emprego | |
| PT96178A (pt) | Metodo para a utilizacao de naftoxazinas no tratamento de condicoes associadas com a esquemia cerebral | |
| BR9202250A (pt) | Processo para a preparacao de semi-sulfato de 3'aminopropil-2-cloroetilsulfona | |
| PT101308A (pt) | Processo para a preparcao de novos n-derivados de (feniletil-beta-ol)-aminas | |
| BR9201522A (pt) | Processo para a preparacao de compostos e composto obtido | |
| PT95185A (pt) | Processo para a preparacao de compostos beta-lactamicos |