NO973580D0 - Fremgangsmåte for fremstilling av mono-N-substituerte tetraazamakrosykliske forbindelser - Google Patents
Fremgangsmåte for fremstilling av mono-N-substituerte tetraazamakrosykliske forbindelserInfo
- Publication number
- NO973580D0 NO973580D0 NO973580A NO973580A NO973580D0 NO 973580 D0 NO973580 D0 NO 973580D0 NO 973580 A NO973580 A NO 973580A NO 973580 A NO973580 A NO 973580A NO 973580 D0 NO973580 D0 NO 973580D0
- Authority
- NO
- Norway
- Prior art keywords
- mono
- preparation
- substituted
- tetraazamacrocyclic
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4140779A DE4140779A1 (de) | 1991-12-06 | 1991-12-06 | Verfahren zur herstellung von mono-n-substituierten tetraazamakrocyclen |
Publications (3)
Publication Number | Publication Date |
---|---|
NO973580L NO973580L (no) | 1993-06-07 |
NO973580D0 true NO973580D0 (no) | 1997-08-04 |
NO303386B1 NO303386B1 (no) | 1998-07-06 |
Family
ID=6446767
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO924690A NO303496B1 (no) | 1991-12-06 | 1992-12-04 | FremgangsmÕte for fremstilling av mono-N-substituerte tetraazasyklododekan- og tetradekanderivater |
NO973579A NO303387B1 (no) | 1991-12-06 | 1997-08-04 | FremgangsmÕte for fremstilling av mono-N-substituerte tetraazasyklododekan- og tetradekanderivater |
NO973581A NO303385B1 (no) | 1991-12-06 | 1997-08-04 | FremgangsmÕte for fremstilling av mono-N-substituerte tetrasyklododekan- og tetradekanderivater |
NO973580A NO303386B1 (no) | 1991-12-06 | 1997-08-04 | FremgangsmÕte for fremstilling av mono-N-substituerte tetraazasyklododekan- og tetradekanderivater |
NO973578A NO303384B1 (no) | 1991-12-06 | 1997-08-04 | FremgangsmÕte for fremstilling av mono-N-substituerte tetraazasykloodekan- og tetradekanderivater |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO924690A NO303496B1 (no) | 1991-12-06 | 1992-12-04 | FremgangsmÕte for fremstilling av mono-N-substituerte tetraazasyklododekan- og tetradekanderivater |
NO973579A NO303387B1 (no) | 1991-12-06 | 1997-08-04 | FremgangsmÕte for fremstilling av mono-N-substituerte tetraazasyklododekan- og tetradekanderivater |
NO973581A NO303385B1 (no) | 1991-12-06 | 1997-08-04 | FremgangsmÕte for fremstilling av mono-N-substituerte tetrasyklododekan- og tetradekanderivater |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO973578A NO303384B1 (no) | 1991-12-06 | 1997-08-04 | FremgangsmÕte for fremstilling av mono-N-substituerte tetraazasykloodekan- og tetradekanderivater |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0545511B1 (no) |
JP (1) | JP3471836B2 (no) |
AT (1) | ATE218131T1 (no) |
CA (1) | CA2084582C (no) |
CZ (1) | CZ290232B6 (no) |
DE (2) | DE4140779A1 (no) |
DK (1) | DK0545511T3 (no) |
ES (1) | ES2176183T3 (no) |
HU (2) | HU9203860D0 (no) |
IL (1) | IL103996A (no) |
NO (5) | NO303496B1 (no) |
PT (1) | PT545511E (no) |
SK (1) | SK282386B6 (no) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4237943C2 (de) * | 1992-11-06 | 1997-10-23 | Schering Ag | Verfahren zur Herstellung von Metallkomplexen der N-beta-Hydroxyalkyl-tri-N-carboxyalkyl-1,4,7,10-tetraazacyclododecan- und N-beta-Hydroxyalkyl-tri-N-carboxyalkyl-1,4,8,11-tetraazacyclotetradecan-Derivate |
DE4317588C2 (de) * | 1993-05-24 | 1998-04-16 | Schering Ag | Fluorhaltige makrocyclische Metallkomplexe, Verfahren zu ihrer Herstellung, sowie ihre Verwendung |
DE4318369C1 (de) * | 1993-05-28 | 1995-02-09 | Schering Ag | Verwendung von makrocyclischen Metallkomplexen als Temperatursonden |
DE4340809C2 (de) * | 1993-11-24 | 2000-08-03 | Schering Ag | 1.4,7,10-Tetraazacyclododecan-Derivate, diese enthaltende pharmazeutische Mittel und Verfahren zu deren Herstellung |
FR2725449B1 (fr) * | 1994-10-05 | 1996-12-27 | Air Liquide | Derives de polyazacycloalcanes, leurs complexes metalliques et produits pharmaceutiques incorporant ces complexes |
DE19724186C2 (de) * | 1997-06-02 | 2002-07-18 | Schering Ag | Verfahren zur Mono- und 1,7-Bis-N-ß-Hydroxyalkylierung von Cyclen und die entsprechenden N-ß-Hydroxyalkyl-1,4,7,10-tetraazacyclododecan-Li-Salz-Komplexe |
IT1297035B1 (it) | 1997-12-30 | 1999-08-03 | Bracco Spa | Derivati dell'acido 1,4,7,10-tetraazaciclododecan-1,4-diacetico |
DE19914101C1 (de) * | 1999-03-22 | 2000-10-12 | Schering Ag | Perfluoralkylamide, ihre Herstellung und ihre Verwendung in der Diagnostik |
DE10002939C1 (de) * | 2000-01-13 | 2001-09-20 | Schering Ag | Paramagnetische DOTA-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung für die Herstellung von pharmazeutischen Mitteln |
WO2012027727A2 (en) * | 2010-08-26 | 2012-03-01 | Kunyuan Cui | Lipomacrocycles and uses thereof |
BR112013027028B1 (pt) | 2011-04-21 | 2020-08-11 | Bayer Intellectual Property Gmbh | Processo para produção de gadobutrol com elevada pureza |
KR101653064B1 (ko) * | 2014-12-26 | 2016-09-09 | 에스티팜 주식회사 | 가도부트롤의 제조방법 |
KR102033964B1 (ko) * | 2018-01-19 | 2019-10-18 | 주식회사 엔지켐생명과학 | 가도테리돌 중간체 및 이를 이용한 가도테리돌 제조방법 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0232751B1 (en) * | 1986-01-23 | 1991-09-11 | E.R. Squibb & Sons, Inc. | 1-substituted-4,7,10-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs |
DE3625417C2 (de) * | 1986-07-28 | 1998-10-08 | Schering Ag | Tetraazacyclododecan-Derivate |
US4994560A (en) * | 1987-06-24 | 1991-02-19 | The Dow Chemical Company | Functionalized polyamine chelants and radioactive rhodium complexes thereof for conjugation to antibodies |
FR2644453A1 (fr) * | 1989-03-20 | 1990-09-21 | Centre Nat Rech Scient | Procede de preparation de tetramines cycliques monofonctionnalisees |
AU625529B2 (en) * | 1989-12-22 | 1992-07-16 | E.R. Squibb & Sons, Inc. | 10-(2'-hydroxy-3'-alkoxy-1,4,7-triscarboxymethyl-1,4,7,10- tetraazacyclododecanes |
NZ236267A (en) * | 1989-12-22 | 1992-12-23 | Squibb & Sons Inc | 10-(2'-hydroxy-3'-polyoxaalkyl)-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane |
DE4009119A1 (de) * | 1990-03-19 | 1991-09-26 | Schering Ag | 1,4,7,10-tetraazacyclododecan-butyltriole, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
DE4035760A1 (de) * | 1990-11-08 | 1992-05-14 | Schering Ag | Mono-n-substituierte 1,4,7,10-tetraazacyclododecan-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
-
1991
- 1991-12-06 DE DE4140779A patent/DE4140779A1/de not_active Withdrawn
-
1992
- 1992-12-03 DK DK92250351T patent/DK0545511T3/da active
- 1992-12-03 ES ES92250351T patent/ES2176183T3/es not_active Expired - Lifetime
- 1992-12-03 AT AT92250351T patent/ATE218131T1/de active
- 1992-12-03 PT PT92250351T patent/PT545511E/pt unknown
- 1992-12-03 EP EP92250351A patent/EP0545511B1/de not_active Expired - Lifetime
- 1992-12-03 DE DE59209957T patent/DE59209957D1/de not_active Expired - Lifetime
- 1992-12-04 CZ CS19923573A patent/CZ290232B6/cs not_active IP Right Cessation
- 1992-12-04 HU HU9203860A patent/HU9203860D0/hu unknown
- 1992-12-04 NO NO924690A patent/NO303496B1/no not_active IP Right Cessation
- 1992-12-04 HU HU9203860A patent/HU224923B1/hu unknown
- 1992-12-04 SK SK3573-92A patent/SK282386B6/sk not_active IP Right Cessation
- 1992-12-04 CA CA002084582A patent/CA2084582C/en not_active Expired - Lifetime
- 1992-12-06 IL IL103996A patent/IL103996A/en not_active IP Right Cessation
- 1992-12-07 JP JP32657092A patent/JP3471836B2/ja not_active Expired - Lifetime
-
1997
- 1997-08-04 NO NO973579A patent/NO303387B1/no not_active IP Right Cessation
- 1997-08-04 NO NO973581A patent/NO303385B1/no not_active IP Right Cessation
- 1997-08-04 NO NO973580A patent/NO303386B1/no not_active IP Right Cessation
- 1997-08-04 NO NO973578A patent/NO303384B1/no not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK1K | Patent expired |