DK0425929T3 - Fremgangsmåde til fremstilling af mellemprodukter og til syntese af N-(2-hydroxyethyl)-2- hydroxymethyl-3,4,5-trihydroxypiperidiner - Google Patents

Fremgangsmåde til fremstilling af mellemprodukter og til syntese af N-(2-hydroxyethyl)-2- hydroxymethyl-3,4,5-trihydroxypiperidiner

Info

Publication number
DK0425929T3
DK0425929T3 DK90120076.6T DK90120076T DK0425929T3 DK 0425929 T3 DK0425929 T3 DK 0425929T3 DK 90120076 T DK90120076 T DK 90120076T DK 0425929 T3 DK0425929 T3 DK 0425929T3
Authority
DK
Denmark
Prior art keywords
trihydroxypiperidines
hydroxymethyl
hydroxyethyl
preparation
intermediates
Prior art date
Application number
DK90120076.6T
Other languages
English (en)
Inventor
Werner Dr Hinsken
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of DK0425929T3 publication Critical patent/DK0425929T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Enzymes And Modification Thereof (AREA)
DK90120076.6T 1989-11-01 1990-10-19 Fremgangsmåde til fremstilling af mellemprodukter og til syntese af N-(2-hydroxyethyl)-2- hydroxymethyl-3,4,5-trihydroxypiperidiner DK0425929T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3936295A DE3936295A1 (de) 1989-11-01 1989-11-01 Verfahren zur herstellung von zwischenprodukten und zur synthese von n-(2-hydroxyethyl)-2-hydroxymethyl-3,4,5-trihydroxypiperidine

Publications (1)

Publication Number Publication Date
DK0425929T3 true DK0425929T3 (da) 1996-04-15

Family

ID=6392610

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90120076.6T DK0425929T3 (da) 1989-11-01 1990-10-19 Fremgangsmåde til fremstilling af mellemprodukter og til syntese af N-(2-hydroxyethyl)-2- hydroxymethyl-3,4,5-trihydroxypiperidiner

Country Status (16)

Country Link
US (1) US5071990A (da)
EP (1) EP0425929B1 (da)
JP (1) JP2858927B2 (da)
KR (1) KR0169977B1 (da)
AT (1) ATE131155T1 (da)
CA (1) CA2028909C (da)
DE (2) DE3936295A1 (da)
DK (1) DK0425929T3 (da)
ES (1) ES2082815T3 (da)
FI (1) FI93443C (da)
GR (1) GR3018765T3 (da)
HU (1) HU205946B (da)
IE (1) IE70059B1 (da)
IL (1) IL96149A (da)
PT (1) PT95737B (da)
ZA (1) ZA908723B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5536732A (en) * 1990-04-27 1996-07-16 Merrell Pharmaceuticals Inc. N-derivatives of 1-deoxy nojirimycin
US5252587A (en) * 1990-04-27 1993-10-12 Merrell Dow Pharmaceuticals, Inc. N-derivatives of 1-deoxy nojirimycin
BRPI0613224A2 (pt) * 2005-06-08 2010-12-28 Amicus Therapeutics Inc método para estabilizar um açúcar triflatado, método para aumentar o rendimento da reação de um produto de açúcar e composição de açúcar triflatado estabilizada
JP2008543784A (ja) * 2005-06-08 2008-12-04 アミカス セラピューティックス インコーポレイテッド 結晶性糖組成物および作製方法
EP2027137B1 (en) * 2005-06-08 2015-02-18 Amicus Therapeutics, Inc. Imino and amino sugar purification
CN103980290B (zh) * 2013-12-06 2016-08-17 华东理工大学 具有杀虫活性的吗啉并环类化合物、及其制备和用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3759929A (en) * 1970-11-02 1973-09-18 Basf Ag Manufacture of {62 -hydroxy carbonyl compounds and/or {60 -unsaturated carbonyl compounds
NO154918C (no) * 1977-08-27 1987-01-14 Bayer Ag Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.
DE2758025A1 (de) * 1977-12-24 1979-07-12 Bayer Ag Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung
JPS54106477A (en) * 1978-02-03 1979-08-21 Nippon Shinyaku Co Ltd Moranoline derivative
DE2922760A1 (de) * 1979-06-05 1980-12-11 Bayer Ag Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel sowie in der tierernaehrung
JPS6011902B2 (ja) * 1979-12-27 1985-03-28 日本新薬株式会社 モラノリンの誘導体
DE3024901A1 (de) * 1980-07-01 1982-01-28 Bayer Ag, 5090 Leverkusen Herbizide mittel auf basis von piperidin-derivaten
DE3038901A1 (de) * 1980-10-15 1982-05-06 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von n-substituierten derivaten des 1-desoxynojirimycins
DE3049446A1 (de) * 1980-12-30 1982-07-29 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von 1,5-didesoxy-1,5-imino-d-glucitol und dessen n-derivaten
DE3611841A1 (de) * 1986-04-09 1987-10-15 Bayer Ag Verfahren zur herstellung von 1-desoxynojirimycin und dessen n-derivaten
JPS62267292A (ja) * 1986-05-14 1987-11-19 Nippon Shinyaku Co Ltd モラノリン誘導体の製法
DE3814549A1 (de) * 1987-10-30 1989-05-18 Bayer Ag N-substituierte derivate von 1-desoxynojirimycin und 1-desoxymannonojirimycin, verfahren zu deren herstellung und deren verwendung in arzneimitteln
EP0344383A1 (en) * 1988-06-02 1989-12-06 Merrell Dow Pharmaceuticals Inc. Novel alpha-Glucosidase inhibitors
DE3906463A1 (de) * 1989-03-01 1990-09-06 Bayer Ag Verfahren zur herstellung von n-hydroxyalkyl-substituierten derivaten von 3,4,5-trihydroxypiperidinen

Also Published As

Publication number Publication date
EP0425929A1 (de) 1991-05-08
PT95737B (pt) 1997-11-28
PT95737A (pt) 1991-09-13
GR3018765T3 (en) 1996-04-30
JP2858927B2 (ja) 1999-02-17
IE903924A1 (en) 1991-05-08
IL96149A0 (en) 1991-07-18
KR910009661A (ko) 1991-06-28
CA2028909C (en) 2002-01-22
ES2082815T3 (es) 1996-04-01
DE3936295A1 (de) 1991-05-02
IL96149A (en) 1995-05-26
ZA908723B (en) 1991-08-28
DE59009951D1 (de) 1996-01-18
EP0425929B1 (de) 1995-12-06
HU205946B (en) 1992-07-28
FI905353A0 (fi) 1990-10-30
HUT55404A (en) 1991-05-28
IE70059B1 (en) 1996-10-16
FI93443B (fi) 1994-12-30
JPH03153666A (ja) 1991-07-01
KR0169977B1 (ko) 1999-02-18
FI93443C (fi) 1995-04-10
CA2028909A1 (en) 1991-05-02
ATE131155T1 (de) 1995-12-15
US5071990A (en) 1991-12-10

Similar Documents

Publication Publication Date Title
ATE206409T1 (de) N-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1-h- benzo(b)(1,5)-diazepin-3-yl)-acetamide
DK0532515T3 (da) Fremstilling af substituerede piperidiner
ES2081636T3 (es) Preparacion de piperidinas sustituidas.
BR9404830A (pt) Composto e processo para sua preparação
ZA891408B (en) Substituted 1,2,4-triazinediones,processes for their preparation and their use
DK204686D0 (da) Quinolylglycinamidderivater og fremgangsmaade til fremstilling deraf
DK0425929T3 (da) Fremgangsmåde til fremstilling af mellemprodukter og til syntese af N-(2-hydroxyethyl)-2- hydroxymethyl-3,4,5-trihydroxypiperidiner
DK111982A (da) N-(2,2,2-trifluorethyl)-n-alkylazolyloxyeddikesureamider,fremgangsmaade og mellemprodukter til deres fremstilling og deres anvendelse som herbicider
BR9400016A (pt) Processo para preparação de compostos, e compostos
DK0427125T3 (da) Benzylselenobenzamider af aniliner og benzylaminer
DE69126612D1 (de) Carbamate des indan-pyrrolidins
DK0647624T3 (da) Mellemprodukter til fremstilling af A-vitamin og carotenoider samt fremgangsmåder til fremstilling deraf
DK0427160T3 (da) Benzylselenobenzamid af aminopyridiner og picolylaminer
IT1182091B (it) Procedimento di sintesi industriale della n-(1'-allil-2'-pirrolidinil) metil)-2-metossi-4,5-azimmidobenzamide
DK0427161T3 (da) Picolylselenobenzamider af aminopyridiner, aniliner og picolylaminer
DK0555283T3 (da) Mellemprodukter ved fremstillingen af 4,5-difluoranthranilinsyre
ITMI913077A0 (it) Processo di sintesi enzimatica di n-(idrossifenil) maleimmidi