PT835137E - Celulas encapsuladas produtoras de particulas virais - Google Patents

Celulas encapsuladas produtoras de particulas virais

Info

Publication number
PT835137E
PT835137E PT96923905T PT96923905T PT835137E PT 835137 E PT835137 E PT 835137E PT 96923905 T PT96923905 T PT 96923905T PT 96923905 T PT96923905 T PT 96923905T PT 835137 E PT835137 E PT 835137E
Authority
PT
Portugal
Prior art keywords
encapsulated cells
viral particles
cells producing
producing viral
genes
Prior art date
Application number
PT96923905T
Other languages
English (en)
Inventor
Robert Michael Saller
Walter H Gunzburg
Brian Salmons
Original Assignee
Gsf Forschungszentrum Umwelt U
Bavarian Nordic As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8097001&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT835137(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gsf Forschungszentrum Umwelt U, Bavarian Nordic As filed Critical Gsf Forschungszentrum Umwelt U
Publication of PT835137E publication Critical patent/PT835137E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
PT96923905T 1995-06-27 1996-06-24 Celulas encapsuladas produtoras de particulas virais PT835137E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK74095 1995-06-27

Publications (1)

Publication Number Publication Date
PT835137E true PT835137E (pt) 2004-12-31

Family

ID=8097001

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96923905T PT835137E (pt) 1995-06-27 1996-06-24 Celulas encapsuladas produtoras de particulas virais

Country Status (22)

Country Link
US (1) US6776985B1 (pt)
EP (1) EP0835137B1 (pt)
JP (2) JP4119952B2 (pt)
KR (1) KR100484883B1 (pt)
CN (1) CN1187095C (pt)
AT (1) ATE309000T1 (pt)
AU (1) AU708273B2 (pt)
CA (1) CA2222559A1 (pt)
CZ (1) CZ286979B6 (pt)
DE (1) DE69633180D1 (pt)
DK (1) DK0835137T3 (pt)
ES (1) ES2253754T3 (pt)
HK (1) HK1010139A1 (pt)
IL (1) IL122119A (pt)
NO (1) NO321427B1 (pt)
NZ (1) NZ312671A (pt)
PL (1) PL185338B1 (pt)
PT (1) PT835137E (pt)
RU (1) RU2187301C2 (pt)
SI (1) SI0835137T1 (pt)
UA (1) UA65525C2 (pt)
WO (1) WO1997001357A1 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69627644T2 (de) 1995-03-09 2004-02-19 GSF-Forschungszentrum für Umwelt und Gesundheit GmbH Vektoren, die therapeutische gene fuer antimikrobielle peptide enthalten, zur verwendung in der gentherapie
DE69633180D1 (de) 1995-06-27 2004-09-23 Bavarian Nordic As Verkapselte zellen die virenpartikeln produzieren
AU713382B2 (en) 1996-03-27 1999-12-02 Bavarian Nordic A/S Cytochrome P450 transducing retroviral vectors
US6540995B1 (en) 1996-03-27 2003-04-01 Bavarian Nordic Research Institute Gmbh Encapsulated cells producing cytochrome P450
EP0994680A1 (en) 1998-05-05 2000-04-26 Koninklijke Philips Electronics N.V. Toothbrush comprising a brush member having a bristle field and an interdental bristle field
EP2289911A3 (en) 2004-03-30 2011-03-30 NsGene A/S Therapeutic use of a growth factor, NsG33
JP2008540347A (ja) 2005-05-03 2008-11-20 フェテリネールメディツィニシュ ウニベルジテート ウィーン 浸透性カプセル
WO2009085850A2 (en) * 2007-12-20 2009-07-09 Ethicon, Incorporated Encapsulated kidney tissue
KR101250925B1 (ko) * 2011-10-28 2013-04-04 한화케미칼 주식회사 캡슐 세포용 구조체
GB201408233D0 (en) 2014-05-09 2014-06-25 Austrianova Singapore Pte Ltd Use of polyanionic composition
ES2959326T3 (es) * 2015-11-24 2024-02-23 Glaxosmithkline Ip Dev Ltd Líneas celulares estables para producción retroviral
RU2749717C2 (ru) * 2015-11-24 2021-06-16 Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед Способ временной трансфекции для продуцирования ретровируса
US11427809B2 (en) 2016-05-25 2022-08-30 Lonza Houston, Inc. Methods for isolating adeno-associated virus using a polydialkylammonium salt
RU2688383C2 (ru) * 2017-07-10 2019-05-21 Федеральное государственное бюджетное образовательное учреждение высшего образования "Саратовский национальный исследовательский государственный университет имени Н.Г. Чернышевского" Способ синтеза белка в культуре бактериальных клеток
CN110615667B (zh) * 2018-06-19 2022-02-15 华北理工大学 基于铁尾矿和碱渣的核壳结构陶粒及其制备方法
WO2022246170A2 (en) * 2021-05-21 2022-11-24 Bionaut Labs Ltd. Systems and methods for microbot-mediated therapeutic delivery
CN115820683B (zh) * 2022-09-28 2024-04-05 西南大学 家蚕Cyp9a20基因及其应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4391909A (en) * 1979-03-28 1983-07-05 Damon Corporation Microcapsules containing viable tissue cells
DD160393A3 (de) * 1980-11-14 1983-07-27 Horst Dautzenberg Mikrokapseln und verfahren zu ihrer herstellung
US4686098A (en) * 1984-05-14 1987-08-11 Merck & Co., Inc. Encapsulated mouse cells transformed with avian retrovirus-bovine growth hormone DNA, and a method of administering BGH in vivo
US4680174A (en) * 1984-05-24 1987-07-14 Damon Biotech, Inc. Induction of immune response by immunization with encapsulated antigen-producing cells
EP0199362A3 (en) * 1985-04-26 1987-10-07 Massachusetts Institute Of Technology System and apparatus for delayed and pulsed release of biologically active substances
CA1310924C (en) * 1986-04-24 1992-12-01 Francis P. Mccormick Infective drug delivery system
DE68927089T2 (de) 1988-05-17 1997-04-03 Sloan Kettering Inst Cancer Retroviraler vektor
US5328470A (en) * 1989-03-31 1994-07-12 The Regents Of The University Of Michigan Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor
DE4021050A1 (de) * 1990-06-29 1992-01-02 Akad Wissenschaften Ddr Verfahren zur herstellung von mikrokapseln
CA2051288C (en) * 1990-09-14 2002-02-05 Robert L. Martuza Viral targeted destruction of neoplastic cells
JPH06500927A (ja) * 1990-12-13 1994-01-27 アメリカ合衆国 高力価の組換えウイルスベクターおよび遺伝子療法に用いられる形質導入標的細胞の持続的及び連続的生産
WO1994029437A1 (en) 1993-06-07 1994-12-22 University Of Medicine & Dentistry Of New Jersey Highly-efficient, self-inactivating, recombination-free, u3-free retroviral vectors
US5688773A (en) 1994-08-17 1997-11-18 The General Hospital Corporation Method of selectively destroying neoplastic cells
EE03492B1 (et) 1994-09-02 2001-08-15 GSF-Forschungszentrum f�r Umwelt und Gesundheit GmbH Mitte-autoinaktiveeruvad ekspressiooni suunavad retroviiruslikud vektorid
DE69633180D1 (de) 1995-06-27 2004-09-23 Bavarian Nordic As Verkapselte zellen die virenpartikeln produzieren
JPH11511979A (ja) 1995-09-06 1999-10-19 ババリアン・ノルディック・リサーチ・インスティテュート・アクティーゼルスカブ ヒト乳癌細胞を含むヒト乳腺細胞を標的として、連結された異種性遺伝子を発現させるためのｗａｐまたはｍｍｔｖ制御配列の使用
AU713382B2 (en) 1996-03-27 1999-12-02 Bavarian Nordic A/S Cytochrome P450 transducing retroviral vectors

Also Published As

Publication number Publication date
UA65525C2 (en) 2004-04-15
AU708273B2 (en) 1999-07-29
ES2253754T3 (es) 2006-06-01
NO321427B1 (no) 2006-05-08
NO975813L (no) 1998-02-23
RU2187301C2 (ru) 2002-08-20
EP0835137B1 (en) 2005-11-09
CN1189104A (zh) 1998-07-29
KR19990028491A (ko) 1999-04-15
WO1997001357A1 (en) 1997-01-16
CA2222559A1 (en) 1997-01-16
NO975813D0 (no) 1997-12-10
DK0835137T3 (da) 2006-03-06
CN1187095C (zh) 2005-02-02
IL122119A0 (en) 1998-04-05
IL122119A (en) 2004-06-01
NZ312671A (en) 1999-10-28
JPH11508768A (ja) 1999-08-03
JP4119952B2 (ja) 2008-07-16
PL324289A1 (en) 1998-05-11
DE69633180D1 (de) 2004-09-23
AU6415496A (en) 1997-01-30
CZ419597A3 (cs) 1998-03-18
KR100484883B1 (ko) 2005-09-02
HK1010139A1 (en) 1999-06-17
JP2008101011A (ja) 2008-05-01
PL185338B1 (pl) 2003-04-30
JP4848348B2 (ja) 2011-12-28
CZ286979B6 (en) 2000-08-16
SI0835137T1 (sl) 2006-04-30
EP0835137A1 (en) 1998-04-15
US6776985B1 (en) 2004-08-17
ATE309000T1 (de) 2005-11-15

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