DE68927089T2 - Retroviraler vektor - Google Patents

Retroviraler vektor

Info

Publication number
DE68927089T2
DE68927089T2 DE68927089T DE68927089T DE68927089T2 DE 68927089 T2 DE68927089 T2 DE 68927089T2 DE 68927089 T DE68927089 T DE 68927089T DE 68927089 T DE68927089 T DE 68927089T DE 68927089 T2 DE68927089 T2 DE 68927089T2
Authority
DE
Germany
Prior art keywords
transcription unit
introducing
sequence
retroviral vector
dna encoding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68927089T
Other languages
English (en)
Other versions
DE68927089D1 (de
Inventor
Eli Gilboa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sloan Kettering Institute for Cancer Research
Original Assignee
Sloan Kettering Institute for Cancer Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22726179&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE68927089(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sloan Kettering Institute for Cancer Research filed Critical Sloan Kettering Institute for Cancer Research
Publication of DE68927089D1 publication Critical patent/DE68927089D1/de
Application granted granted Critical
Publication of DE68927089T2 publication Critical patent/DE68927089T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE68927089T 1988-05-17 1989-05-17 Retroviraler vektor Expired - Fee Related DE68927089T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19662888A 1988-05-17 1988-05-17
PCT/US1989/002138 WO1989011539A1 (en) 1988-05-17 1989-05-17 Retroviral vector

Publications (2)

Publication Number Publication Date
DE68927089D1 DE68927089D1 (de) 1996-10-10
DE68927089T2 true DE68927089T2 (de) 1997-04-03

Family

ID=22726179

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68927089T Expired - Fee Related DE68927089T2 (de) 1988-05-17 1989-05-17 Retroviraler vektor

Country Status (8)

Country Link
EP (1) EP0371119B1 (de)
JP (1) JPH02504344A (de)
AT (1) ATE142268T1 (de)
AU (1) AU631554B2 (de)
CA (1) CA1335798C (de)
DE (1) DE68927089T2 (de)
DK (1) DK13290A (de)
WO (1) WO1989011539A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5650148A (en) * 1988-12-15 1997-07-22 The Regents Of The University Of California Method of grafting genetically modified cells to treat defects, disease or damage of the central nervous system
GB8901778D0 (en) * 1989-01-27 1989-03-15 Univ Court Of The University O Manipulatory technique
US6251675B1 (en) * 1989-05-25 2001-06-26 Duke University Methods utilizing mutant rev genes encoding transdominant repressors of HIV replication
US5871958A (en) * 1989-05-25 1999-02-16 Duke University Mutant rev genes encoding transdominant repressors of HIV replication
GB2269175A (en) * 1992-07-31 1994-02-02 Imperial College Retroviral vectors
JPH08505872A (ja) * 1993-01-22 1996-06-25 ユニバーシティ・リサーチ・コーポレイション 治療剤の局所化
FR2707091B1 (fr) * 1993-06-30 1997-04-04 Cohen Haguenauer Odile Vecteur rétroviral pour le transfert et l'expression de gènes dans des cellules eucaryotes.
AU7477394A (en) * 1993-07-30 1995-03-27 University Of Medicine And Dentistry Of New Jersey Efficient gene transfer into primary lymphocytes
US5902880A (en) * 1994-08-19 1999-05-11 Ribozyme Pharmaceuticals, Inc. RNA polymerase III-based expression of therapeutic RNAs
US6146886A (en) 1994-08-19 2000-11-14 Ribozyme Pharmaceuticals, Inc. RNA polymerase III-based expression of therapeutic RNAs
RU2199585C2 (ru) 1994-09-02 2003-02-27 ГСФ-Форшунгсцентрум фюр Умвельт унд Гезундхайт ГмбХ Ретровирусная векторная конструкция, подвергающаяся промоторной конверсии, способ введения гомологичных или гетерологичных нуклеотидных последовательностей в человеческие или животные клетки in vitro и/или in vivo, рекомбинантная ретровирусная частица, фармацевтическая композиция для генной терапии
FR2727429B1 (fr) 1994-11-30 1997-11-28 Haguenauer Odile Cohen Lignees d'encapsidation et vecteurs d'expression pour la transcomplementation de vecteurs retroviraux defectifs
PT817858E (pt) 1995-03-09 2003-09-30 Gsf Forschungszentrum Umwelt U Preparacoes fotoprotectoras que compreendem derivados de triazina
DK0835137T3 (da) 1995-06-27 2006-03-06 Bavarian Nordic As Indkapslede celler, som danner viruspartikler
US6540995B1 (en) 1996-03-27 2003-04-01 Bavarian Nordic Research Institute Gmbh Encapsulated cells producing cytochrome P450
PL188323B1 (pl) 1996-03-27 2005-01-31 Bavarian Nordic As Kapsuła zawierająca komórki i jej zastosowanie oraz kompozycja i środek farmaceutyczny
ATE278029T1 (de) 1998-01-06 2004-10-15 Inst Virologie Teilrechtsfaehi Rekonstituierender retroviraler vektor (recon vektor) für gezielte genexpression

Also Published As

Publication number Publication date
EP0371119A4 (en) 1990-12-05
EP0371119A1 (de) 1990-06-06
ATE142268T1 (de) 1996-09-15
DK13290A (da) 1990-03-16
DK13290D0 (da) 1990-01-16
DE68927089D1 (de) 1996-10-10
AU631554B2 (en) 1992-12-03
WO1989011539A1 (en) 1989-11-30
AU3740489A (en) 1989-12-12
CA1335798C (en) 1995-06-06
EP0371119B1 (de) 1996-09-04
JPH02504344A (ja) 1990-12-13

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8328 Change in the person/name/address of the agent

Free format text: DERZEIT KEIN VERTRETER BESTELLT

8339 Ceased/non-payment of the annual fee