PT83134B - Processo para a preparacao de sais de adicao de acido sulfurico - Google Patents

Processo para a preparacao de sais de adicao de acido sulfurico

Info

Publication number
PT83134B
PT83134B PT83134A PT8313486A PT83134B PT 83134 B PT83134 B PT 83134B PT 83134 A PT83134 A PT 83134A PT 8313486 A PT8313486 A PT 8313486A PT 83134 B PT83134 B PT 83134B
Authority
PT
Portugal
Prior art keywords
salts
preparation
sulfuric acid
acid adhesion
adhesion
Prior art date
Application number
PT83134A
Other languages
English (en)
Portuguese (pt)
Other versions
PT83134A (en
Inventor
Murray Arthur Kaplan
Thomas W Hudyma
Robert Alan Lipper
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of PT83134A publication Critical patent/PT83134A/pt
Publication of PT83134B publication Critical patent/PT83134B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicinal Preparation (AREA)
PT83134A 1985-08-05 1986-08-04 Processo para a preparacao de sais de adicao de acido sulfurico PT83134B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76223585A 1985-08-05 1985-08-05

Publications (2)

Publication Number Publication Date
PT83134A PT83134A (en) 1986-09-01
PT83134B true PT83134B (pt) 1989-07-31

Family

ID=25064475

Family Applications (1)

Application Number Title Priority Date Filing Date
PT83134A PT83134B (pt) 1985-08-05 1986-08-04 Processo para a preparacao de sais de adicao de acido sulfurico

Country Status (34)

Country Link
JP (1) JPH0615548B2 (it)
KR (1) KR930003121B1 (it)
AR (1) AR243894A1 (it)
AT (1) AT390957B (it)
AU (1) AU597262B2 (it)
BE (1) BE905219A (it)
CA (1) CA1284994C (it)
CH (1) CH675581A5 (it)
CS (2) CS276717B6 (it)
CY (1) CY1614A (it)
DD (2) DD254941A5 (it)
DE (1) DE3626375A1 (it)
DK (1) DK162053C (it)
EG (1) EG18003A (it)
ES (1) ES2002112A6 (it)
FI (1) FI84484C (it)
FR (1) FR2585705B1 (it)
GB (1) GB2179936B (it)
GR (1) GR862055B (it)
HK (1) HK99691A (it)
HU (1) HU196602B (it)
IE (1) IE59222B1 (it)
IL (1) IL79608A (it)
IT (1) IT1197067B (it)
LU (2) LU86540A1 (it)
MY (1) MY102212A (it)
NL (1) NL8601991A (it)
OA (1) OA08672A (it)
PT (1) PT83134B (it)
SE (1) SE469633B (it)
SG (1) SG79791G (it)
SU (1) SU1516013A3 (it)
YU (1) YU45793B (it)
ZA (1) ZA865842B (it)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4883868A (en) * 1984-12-27 1989-11-28 Banyu Pharmaceutical Co., Ltd. 7-amino-3-(substituted isoindolinium)methyl-3-cephem derivatives
US4959469A (en) * 1984-12-27 1990-09-25 Banyu Pharmaceutical Company, Ltd. Crystalline cephalosporin compounds
US4910301A (en) * 1985-08-05 1990-03-20 Bristol-Myers Company Cefepime cephalosporin salts
US5244891A (en) * 1985-08-05 1993-09-14 Bristol-Myers Squibb Company Injectable compositions of cefepime dihydrochloride hydrate
US4808617A (en) * 1985-12-18 1989-02-28 Bristol-Myers Company Lyophilized or precipitated cephalosporin zwitterion and salt combination
EP0321562B1 (en) * 1987-06-25 1993-11-24 Banyu Pharmaceutical Co., Ltd. Crystalline cephalosporin compounds, process for their preparation, and intermediates for their preparation
JPH02101081A (ja) * 1988-10-08 1990-04-12 Meiji Seika Kaisha Ltd セファロスポリン誘導体結晶性二塩酸塩及びその製造法
CA2011116C (en) * 1989-03-06 1999-11-16 Murray A. Kaplan Lyophilized bmy-28142 dihydrochloride for parenteral use
CA2101571A1 (en) * 1992-09-08 1994-03-09 Elizabeth A. Garofalo Crystalline dihydrate of a cephalosporin dihydrate salt and injectable compositions thereof
EP0638573A1 (en) * 1993-08-10 1995-02-15 Lucky Ltd. Crystalline hydrates of cephalosporin and process for preparation thereof
JP4616844B2 (ja) 2003-12-23 2011-01-19 サンド・ゲーエムベーハー セファロスポリン合成に使用するための中間体の生成プロセス
WO2008056221A2 (en) * 2006-11-06 2008-05-15 Orchid Chemicals & Pharmaceuticals Limited Crystalline sulfate salt of cephalosporin antibiotic
DE102012101680A1 (de) * 2012-02-29 2013-08-29 Aicuris Gmbh & Co. Kg Pharmazeutische Zubereitung enthaltend ein antiviral wirksames Dihydrochinazolinderivat

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55151588A (en) * 1979-05-14 1980-11-26 Takeda Chem Ind Ltd Preparation of cephalosporin salt crystal
US4406899A (en) * 1982-03-04 1983-09-27 Bristol-Myers Company Cephalosporins
CA1213882A (en) * 1982-03-04 1986-11-12 Jun Okumura Cephalosporins
US4525473A (en) * 1983-03-30 1985-06-25 Bristol-Myers Company Cephalosporins
DE3419015A1 (de) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von cephalosporinen
GB8424692D0 (en) * 1984-10-01 1984-11-07 Glaxo Group Ltd Chemical compounds
GB2165245B (en) * 1984-10-01 1988-05-25 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
YU137186A (en) 1987-12-31
CH675581A5 (it) 1990-10-15
AT390957B (de) 1990-07-25
FR2585705A1 (fr) 1987-02-06
AU597262B2 (en) 1990-05-31
ZA865842B (en) 1987-04-29
HK99691A (en) 1991-12-13
FI84484C (fi) 1991-12-10
OA08672A (en) 1989-03-31
IE59222B1 (en) 1994-01-26
DE3626375A1 (de) 1987-02-12
KR930003121B1 (ko) 1993-04-19
SE8603308L (sv) 1987-02-06
BE905219A (fr) 1987-02-04
CS276717B6 (en) 1992-08-12
YU45793B (sh) 1992-07-20
IT1197067B (it) 1988-11-25
HUT41802A (en) 1987-05-28
MY102212A (en) 1992-05-15
FI863155A (fi) 1987-02-06
IT8621409A1 (it) 1988-02-04
FR2585705B1 (fr) 1989-01-13
DK371886A (da) 1987-02-06
DK162053B (da) 1991-09-09
IL79608A (en) 1991-07-18
CY1614A (en) 1992-07-10
DD254941A5 (de) 1988-03-16
CS276849B6 (en) 1992-08-12
DK371886D0 (da) 1986-08-04
DK162053C (da) 1992-02-10
HU196602B (en) 1988-12-28
SE8603308D0 (sv) 1986-08-04
JPH0615548B2 (ja) 1994-03-02
KR880002530A (ko) 1988-05-09
JPS62103090A (ja) 1987-05-13
SU1516013A3 (ru) 1989-10-15
ES2002112A6 (es) 1988-07-16
NL8601991A (nl) 1987-03-02
PT83134A (en) 1986-09-01
GB2179936A (en) 1987-03-18
LU86540A1 (fr) 1987-03-06
DD268395A5 (de) 1989-05-31
GB8618989D0 (en) 1986-09-17
GR862055B (en) 1986-12-24
IT8621409A0 (it) 1986-08-04
EG18003A (en) 1991-08-30
SG79791G (en) 1991-11-15
ATA211086A (de) 1990-01-15
IE862078L (en) 1987-02-05
AR243894A1 (es) 1993-09-30
FI863155A0 (fi) 1986-08-01
FI84484B (fi) 1991-08-30
AU6069486A (en) 1987-02-12
SE469633B (sv) 1993-08-09
GB2179936B (en) 1989-04-26
IL79608A0 (en) 1986-11-30
LU88574I2 (fr) 1995-03-01
CA1284994C (en) 1991-06-18

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