YU137186A - Process for obtaining cephalosporinic salts - Google Patents

Process for obtaining cephalosporinic salts

Info

Publication number
YU137186A
YU137186A YU01371/86A YU137186A YU137186A YU 137186 A YU137186 A YU 137186A YU 01371/86 A YU01371/86 A YU 01371/86A YU 137186 A YU137186 A YU 137186A YU 137186 A YU137186 A YU 137186A
Authority
YU
Yugoslavia
Prior art keywords
cephalosporinic
salts
obtaining
obtaining cephalosporinic
cephalosporinic salts
Prior art date
Application number
YU01371/86A
Other versions
YU45793B (en
Inventor
M A Kaplan
T W Hudyma
R A Lipper
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of YU137186A publication Critical patent/YU137186A/en
Publication of YU45793B publication Critical patent/YU45793B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicinal Preparation (AREA)
YU137186A 1985-08-05 1986-07-31 PROCESS FOR PREPARATION OF STABLE CRYSTAL ADDITIONAL SALTS OF 7- (ALPHA- (2-AMINOTHIAZOLA-4-YL) -ALPHA- (Z) -METHOXYIMINO ACETAMIDO / -3- / (1-METHYL-1-PYROLIDINO) -METHYL / -3- CEFEM-CARBOXYLATES WITH ACIDS, AS WELL AS PREPARATIONS CONTAINING THEM YU45793B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76223585A 1985-08-05 1985-08-05

Publications (2)

Publication Number Publication Date
YU137186A true YU137186A (en) 1987-12-31
YU45793B YU45793B (en) 1992-07-20

Family

ID=25064475

Family Applications (1)

Application Number Title Priority Date Filing Date
YU137186A YU45793B (en) 1985-08-05 1986-07-31 PROCESS FOR PREPARATION OF STABLE CRYSTAL ADDITIONAL SALTS OF 7- (ALPHA- (2-AMINOTHIAZOLA-4-YL) -ALPHA- (Z) -METHOXYIMINO ACETAMIDO / -3- / (1-METHYL-1-PYROLIDINO) -METHYL / -3- CEFEM-CARBOXYLATES WITH ACIDS, AS WELL AS PREPARATIONS CONTAINING THEM

Country Status (34)

Country Link
JP (1) JPH0615548B2 (en)
KR (1) KR930003121B1 (en)
AR (1) AR243894A1 (en)
AT (1) AT390957B (en)
AU (1) AU597262B2 (en)
BE (1) BE905219A (en)
CA (1) CA1284994C (en)
CH (1) CH675581A5 (en)
CS (2) CS276849B6 (en)
CY (1) CY1614A (en)
DD (2) DD254941A5 (en)
DE (1) DE3626375A1 (en)
DK (1) DK162053C (en)
EG (1) EG18003A (en)
ES (1) ES2002112A6 (en)
FI (1) FI84484C (en)
FR (1) FR2585705B1 (en)
GB (1) GB2179936B (en)
GR (1) GR862055B (en)
HK (1) HK99691A (en)
HU (1) HU196602B (en)
IE (1) IE59222B1 (en)
IL (1) IL79608A (en)
IT (1) IT1197067B (en)
LU (2) LU86540A1 (en)
MY (1) MY102212A (en)
NL (1) NL8601991A (en)
OA (1) OA08672A (en)
PT (1) PT83134B (en)
SE (1) SE469633B (en)
SG (1) SG79791G (en)
SU (1) SU1516013A3 (en)
YU (1) YU45793B (en)
ZA (1) ZA865842B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4883868A (en) * 1984-12-27 1989-11-28 Banyu Pharmaceutical Co., Ltd. 7-amino-3-(substituted isoindolinium)methyl-3-cephem derivatives
US4959469A (en) * 1984-12-27 1990-09-25 Banyu Pharmaceutical Company, Ltd. Crystalline cephalosporin compounds
US4910301A (en) * 1985-08-05 1990-03-20 Bristol-Myers Company Cefepime cephalosporin salts
US5244891A (en) * 1985-08-05 1993-09-14 Bristol-Myers Squibb Company Injectable compositions of cefepime dihydrochloride hydrate
US4808617A (en) * 1985-12-18 1989-02-28 Bristol-Myers Company Lyophilized or precipitated cephalosporin zwitterion and salt combination
EP0321562B1 (en) * 1987-06-25 1993-11-24 Banyu Pharmaceutical Co., Ltd. Crystalline cephalosporin compounds, process for their preparation, and intermediates for their preparation
JPH02101081A (en) * 1988-10-08 1990-04-12 Meiji Seika Kaisha Ltd Crystalline dihydrochloride of cephalosporin derivative and production thereof
CA2011116C (en) * 1989-03-06 1999-11-16 Murray A. Kaplan Lyophilized bmy-28142 dihydrochloride for parenteral use
CA2101571A1 (en) * 1992-09-08 1994-03-09 Elizabeth A. Garofalo Crystalline dihydrate of a cephalosporin dihydrate salt and injectable compositions thereof
EP0638573A1 (en) * 1993-08-10 1995-02-15 Lucky Ltd. Crystalline hydrates of cephalosporin and process for preparation thereof
DE602004011685T2 (en) 2003-12-23 2009-02-05 Sandoz Gmbh PROCESS FOR PREPARING INTERMEDIATE PRODUCTS FOR USE IN THE CEFALOSPORIN SYNTHESIS
WO2008056221A2 (en) * 2006-11-06 2008-05-15 Orchid Chemicals & Pharmaceuticals Limited Crystalline sulfate salt of cephalosporin antibiotic
DE102012101680A1 (en) * 2012-02-29 2013-08-29 Aicuris Gmbh & Co. Kg Pharmaceutical preparation containing an antiviral dihydroquinazoline derivative

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55151588A (en) * 1979-05-14 1980-11-26 Takeda Chem Ind Ltd Preparation of cephalosporin salt crystal
CA1213882A (en) * 1982-03-04 1986-11-12 Jun Okumura Cephalosporins
US4406899A (en) * 1982-03-04 1983-09-27 Bristol-Myers Company Cephalosporins
US4525473A (en) * 1983-03-30 1985-06-25 Bristol-Myers Company Cephalosporins
DE3419015A1 (en) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen METHOD FOR PRODUCING CEPHALOSPORINES
GB8424692D0 (en) * 1984-10-01 1984-11-07 Glaxo Group Ltd Chemical compounds
GB2165245B (en) * 1984-10-01 1988-05-25 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
SE8603308D0 (en) 1986-08-04
CS276717B6 (en) 1992-08-12
IE59222B1 (en) 1994-01-26
KR930003121B1 (en) 1993-04-19
SE8603308L (en) 1987-02-06
FR2585705B1 (en) 1989-01-13
DE3626375A1 (en) 1987-02-12
AU597262B2 (en) 1990-05-31
FR2585705A1 (en) 1987-02-06
JPH0615548B2 (en) 1994-03-02
IT8621409A1 (en) 1988-02-04
ZA865842B (en) 1987-04-29
DK162053C (en) 1992-02-10
DD254941A5 (en) 1988-03-16
FI84484B (en) 1991-08-30
IL79608A0 (en) 1986-11-30
AT390957B (en) 1990-07-25
YU45793B (en) 1992-07-20
HU196602B (en) 1988-12-28
FI84484C (en) 1991-12-10
PT83134B (en) 1989-07-31
GB2179936B (en) 1989-04-26
CA1284994C (en) 1991-06-18
DD268395A5 (en) 1989-05-31
IL79608A (en) 1991-07-18
GB8618989D0 (en) 1986-09-17
GR862055B (en) 1986-12-24
BE905219A (en) 1987-02-04
IE862078L (en) 1987-02-05
FI863155A0 (en) 1986-08-01
IT1197067B (en) 1988-11-25
FI863155A (en) 1987-02-06
SG79791G (en) 1991-11-15
JPS62103090A (en) 1987-05-13
DK162053B (en) 1991-09-09
CH675581A5 (en) 1990-10-15
OA08672A (en) 1989-03-31
IT8621409A0 (en) 1986-08-04
PT83134A (en) 1986-09-01
SU1516013A3 (en) 1989-10-15
CS276849B6 (en) 1992-08-12
SE469633B (en) 1993-08-09
AR243894A1 (en) 1993-09-30
LU88574I2 (en) 1995-03-01
AU6069486A (en) 1987-02-12
ES2002112A6 (en) 1988-07-16
DK371886A (en) 1987-02-06
GB2179936A (en) 1987-03-18
HK99691A (en) 1991-12-13
CY1614A (en) 1992-07-10
MY102212A (en) 1992-05-15
NL8601991A (en) 1987-03-02
DK371886D0 (en) 1986-08-04
HUT41802A (en) 1987-05-28
KR880002530A (en) 1988-05-09
EG18003A (en) 1991-08-30
ATA211086A (en) 1990-01-15
LU86540A1 (en) 1987-03-06

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