IT1197067B - Cephalosporin salts and injectable compositions - Google Patents

Cephalosporin salts and injectable compositions

Info

Publication number
IT1197067B
IT1197067B IT21409/86A IT2140986A IT1197067B IT 1197067 B IT1197067 B IT 1197067B IT 21409/86 A IT21409/86 A IT 21409/86A IT 2140986 A IT2140986 A IT 2140986A IT 1197067 B IT1197067 B IT 1197067B
Authority
IT
Italy
Prior art keywords
injectable compositions
cephalosporin salts
cephalosporin
salts
injectable
Prior art date
Application number
IT21409/86A
Other languages
Italian (it)
Other versions
IT8621409A1 (en
IT8621409A0 (en
Inventor
Murray A Kaplan
Thomas W Hudyma
Robert A Lipper
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IT8621409A0 publication Critical patent/IT8621409A0/en
Publication of IT8621409A1 publication Critical patent/IT8621409A1/en
Application granted granted Critical
Publication of IT1197067B publication Critical patent/IT1197067B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicinal Preparation (AREA)
IT21409/86A 1985-08-05 1986-08-04 Cephalosporin salts and injectable compositions IT1197067B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76223585A 1985-08-05 1985-08-05

Publications (3)

Publication Number Publication Date
IT8621409A0 IT8621409A0 (en) 1986-08-04
IT8621409A1 IT8621409A1 (en) 1988-02-04
IT1197067B true IT1197067B (en) 1988-11-25

Family

ID=25064475

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21409/86A IT1197067B (en) 1985-08-05 1986-08-04 Cephalosporin salts and injectable compositions

Country Status (34)

Country Link
JP (1) JPH0615548B2 (en)
KR (1) KR930003121B1 (en)
AR (1) AR243894A1 (en)
AT (1) AT390957B (en)
AU (1) AU597262B2 (en)
BE (1) BE905219A (en)
CA (1) CA1284994C (en)
CH (1) CH675581A5 (en)
CS (2) CS276849B6 (en)
CY (1) CY1614A (en)
DD (2) DD254941A5 (en)
DE (1) DE3626375A1 (en)
DK (1) DK162053C (en)
EG (1) EG18003A (en)
ES (1) ES2002112A6 (en)
FI (1) FI84484C (en)
FR (1) FR2585705B1 (en)
GB (1) GB2179936B (en)
GR (1) GR862055B (en)
HK (1) HK99691A (en)
HU (1) HU196602B (en)
IE (1) IE59222B1 (en)
IL (1) IL79608A (en)
IT (1) IT1197067B (en)
LU (2) LU88574I2 (en)
MY (1) MY102212A (en)
NL (1) NL8601991A (en)
OA (1) OA08672A (en)
PT (1) PT83134B (en)
SE (1) SE469633B (en)
SG (1) SG79791G (en)
SU (1) SU1516013A3 (en)
YU (1) YU45793B (en)
ZA (1) ZA865842B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4883868A (en) * 1984-12-27 1989-11-28 Banyu Pharmaceutical Co., Ltd. 7-amino-3-(substituted isoindolinium)methyl-3-cephem derivatives
US4959469A (en) * 1984-12-27 1990-09-25 Banyu Pharmaceutical Company, Ltd. Crystalline cephalosporin compounds
US4910301A (en) * 1985-08-05 1990-03-20 Bristol-Myers Company Cefepime cephalosporin salts
US5244891A (en) * 1985-08-05 1993-09-14 Bristol-Myers Squibb Company Injectable compositions of cefepime dihydrochloride hydrate
US4808617A (en) * 1985-12-18 1989-02-28 Bristol-Myers Company Lyophilized or precipitated cephalosporin zwitterion and salt combination
KR950010084B1 (en) * 1987-06-25 1995-09-06 반유세이야꾸 가부시끼가이샤 Crystalline Cephalosporin Compounds, Preparations thereof and Intermediates thereof
JPH02101081A (en) * 1988-10-08 1990-04-12 Meiji Seika Kaisha Ltd Crystalline dihydrochloride of cephalosporin derivative and production thereof
CA2011116C (en) * 1989-03-06 1999-11-16 Murray A. Kaplan Lyophilized bmy-28142 dihydrochloride for parenteral use
CA2101571A1 (en) * 1992-09-08 1994-03-09 Elizabeth A. Garofalo Crystalline dihydrate of a cephalosporin dihydrate salt and injectable compositions thereof
HU222244B1 (en) * 1993-03-12 2003-05-28 Pharmacia & Upjohn Co. Crystalline ceftiofur free acid, process for preparing it and pharmaceutical composition containing it
EP0638573A1 (en) * 1993-08-10 1995-02-15 Lucky Ltd. Crystalline hydrates of cephalosporin and process for preparation thereof
JP4616844B2 (en) 2003-12-23 2011-01-19 サンド・ゲーエムベーハー Production process of intermediates for use in the synthesis of cephalosporin
WO2008056221A2 (en) * 2006-11-06 2008-05-15 Orchid Chemicals & Pharmaceuticals Limited Crystalline sulfate salt of cephalosporin antibiotic
DE102012101680A1 (en) * 2012-02-29 2013-08-29 Aicuris Gmbh & Co. Kg Pharmaceutical preparation containing an antiviral dihydroquinazoline derivative

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55151588A (en) * 1979-05-14 1980-11-26 Takeda Chem Ind Ltd Preparation of cephalosporin salt crystal
US4406899A (en) * 1982-03-04 1983-09-27 Bristol-Myers Company Cephalosporins
CA1213882A (en) * 1982-03-04 1986-11-12 Jun Okumura Cephalosporins
US4525473A (en) * 1983-03-30 1985-06-25 Bristol-Myers Company Cephalosporins
DE3419015A1 (en) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen METHOD FOR PRODUCING CEPHALOSPORINES
GB2165245B (en) * 1984-10-01 1988-05-25 Glaxo Group Ltd Chemical compounds
GB8424692D0 (en) * 1984-10-01 1984-11-07 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
DK371886D0 (en) 1986-08-04
BE905219A (en) 1987-02-04
NL8601991A (en) 1987-03-02
HU196602B (en) 1988-12-28
HUT41802A (en) 1987-05-28
KR930003121B1 (en) 1993-04-19
SE8603308L (en) 1987-02-06
IT8621409A1 (en) 1988-02-04
SE8603308D0 (en) 1986-08-04
IE862078L (en) 1987-02-05
CS276717B6 (en) 1992-08-12
FI863155A7 (en) 1987-02-06
CA1284994C (en) 1991-06-18
YU45793B (en) 1992-07-20
SU1516013A3 (en) 1989-10-15
ZA865842B (en) 1987-04-29
PT83134A (en) 1986-09-01
FI84484C (en) 1991-12-10
GB8618989D0 (en) 1986-09-17
EG18003A (en) 1991-08-30
AU6069486A (en) 1987-02-12
FR2585705B1 (en) 1989-01-13
IL79608A0 (en) 1986-11-30
AR243894A1 (en) 1993-09-30
JPS62103090A (en) 1987-05-13
YU137186A (en) 1987-12-31
PT83134B (en) 1989-07-31
ATA211086A (en) 1990-01-15
SE469633B (en) 1993-08-09
FI84484B (en) 1991-08-30
OA08672A (en) 1989-03-31
DK371886A (en) 1987-02-06
ES2002112A6 (en) 1988-07-16
DK162053B (en) 1991-09-09
DD268395A5 (en) 1989-05-31
CH675581A5 (en) 1990-10-15
AT390957B (en) 1990-07-25
DK162053C (en) 1992-02-10
FI863155A0 (en) 1986-08-01
IE59222B1 (en) 1994-01-26
FR2585705A1 (en) 1987-02-06
DD254941A5 (en) 1988-03-16
IL79608A (en) 1991-07-18
DE3626375A1 (en) 1987-02-12
IT8621409A0 (en) 1986-08-04
CS276849B6 (en) 1992-08-12
JPH0615548B2 (en) 1994-03-02
KR880002530A (en) 1988-05-09
GB2179936B (en) 1989-04-26
MY102212A (en) 1992-05-15
CY1614A (en) 1992-07-10
LU88574I2 (en) 1995-03-01
AU597262B2 (en) 1990-05-31
GR862055B (en) 1986-12-24
HK99691A (en) 1991-12-13
GB2179936A (en) 1987-03-18
LU86540A1 (en) 1987-03-06
SG79791G (en) 1991-11-15

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Legal Events

Date Code Title Description
MEDD Supplementary protection certificate for pharmaceutical products: granted

Free format text: CCP 496, 19950411; BRISTOL-MYERS SQUIBB COMPANY

TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970829