PT755458E - Marcadores quimioluminescentes electrogerados para analise e/ou referencia - Google Patents
Marcadores quimioluminescentes electrogerados para analise e/ou referenciaInfo
- Publication number
- PT755458E PT755458E PT96903716T PT96903716T PT755458E PT 755458 E PT755458 E PT 755458E PT 96903716 T PT96903716 T PT 96903716T PT 96903716 T PT96903716 T PT 96903716T PT 755458 E PT755458 E PT 755458E
- Authority
- PT
- Portugal
- Prior art keywords
- coreactant
- produces
- ecl
- thcooh
- dpas
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
- C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6825—Nucleic acid detection involving sensors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Dental Preparations (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/385,864 US5786141A (en) | 1994-08-26 | 1995-02-09 | Electrogenerated chemiluminescence labels for analysis and/or referencing |
Publications (1)
Publication Number | Publication Date |
---|---|
PT755458E true PT755458E (pt) | 2005-01-31 |
Family
ID=23523173
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT96903716T PT755458E (pt) | 1995-02-09 | 1996-02-09 | Marcadores quimioluminescentes electrogerados para analise e/ou referencia |
Country Status (11)
Country | Link |
---|---|
US (2) | US5786141A (pt) |
EP (1) | EP0755458B1 (pt) |
JP (1) | JP3989019B2 (pt) |
AT (1) | ATE274601T1 (pt) |
AU (1) | AU709592B2 (pt) |
CA (1) | CA2186503C (pt) |
DE (1) | DE69633212T2 (pt) |
DK (1) | DK0755458T3 (pt) |
ES (1) | ES2227580T3 (pt) |
PT (1) | PT755458E (pt) |
WO (1) | WO1996024690A1 (pt) |
Families Citing this family (72)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20010003647A1 (en) * | 1995-06-07 | 2001-06-14 | Ji Sun | Coreatant-including electrochemiluminescent compounds, methods, systems and kits utilizing same |
US6319670B1 (en) | 1995-05-09 | 2001-11-20 | Meso Scale Technology Llp | Methods and apparatus for improved luminescence assays using microparticles |
US6613583B1 (en) | 1997-06-27 | 2003-09-02 | Igen International, Inc. | Electrochemiluminescent label based on multimetallic assemblies |
US6153674A (en) * | 1998-01-30 | 2000-11-28 | 3M Innovative Properties Company | Fire barrier material |
US6200531B1 (en) * | 1998-05-11 | 2001-03-13 | Igen International, Inc. | Apparatus for carrying out electrochemiluminescence test measurements |
US7186568B1 (en) | 2000-06-26 | 2007-03-06 | Lumigen Inc. | Electrochemiluminescence from acridan compounds |
JP2006170615A (ja) * | 2001-01-19 | 2006-06-29 | Shigeori Takenaka | 遺伝子の検出方法、検出装置、並びに検出用チップ |
CN100465619C (zh) | 2001-06-29 | 2009-03-04 | 梅索磅秤技术有限公司 | 发光测试检测用的检测板、读数系统和方法 |
EP1412487B1 (en) | 2001-07-30 | 2010-06-16 | Meso Scale Technologies LLC | Assay electrodes having immobilized lipid/protein layers and methods of making and using the same |
AU2002341621A1 (en) | 2001-09-10 | 2003-03-24 | Meso Scale Technologies, Llc | Methods, reagents, kits and apparatus for protein function analysis |
CA2493905A1 (en) * | 2002-06-20 | 2003-12-31 | Sudeep M. Kumar | Electrochemiluminescence flow cell and flow cell components |
US7920906B2 (en) | 2005-03-10 | 2011-04-05 | Dexcom, Inc. | System and methods for processing analyte sensor data for sensor calibration |
US9247900B2 (en) | 2004-07-13 | 2016-02-02 | Dexcom, Inc. | Analyte sensor |
WO2006127694A2 (en) | 2004-07-13 | 2006-11-30 | Dexcom, Inc. | Analyte sensor |
US20060020192A1 (en) | 2004-07-13 | 2006-01-26 | Dexcom, Inc. | Transcutaneous analyte sensor |
WO2006075497A1 (ja) * | 2004-12-21 | 2006-07-20 | Kyoto University | プローブユニット、ヌクレオチド領域の同定装置、及びヌクレオチド領域の同定方法 |
WO2006076650A2 (en) * | 2005-01-12 | 2006-07-20 | Applera Corporation | Compositions, methods, and kits for selective amplification of nucleic acids |
KR101385384B1 (ko) * | 2005-06-03 | 2014-04-14 | 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 | 단일 패러데이 전극에서의 전기발생 화학발광 및 전기화학 |
SI2271938T1 (sl) | 2008-04-11 | 2014-07-31 | Board Of Regents Of The University Of Texas System | Postopek in naprava za ojačenje električno generirane kemiluminiscence nanodelcev |
EP2626693A3 (en) * | 2008-05-08 | 2014-10-01 | Board of Regents of the University of Texas System | Luminescent nanostructured materials for use in electrogenerated chemiluminescence |
US20100261292A1 (en) | 2009-04-10 | 2010-10-14 | Meso Scale Technologies, Llc | Methods for Conducting Assays |
US20110143947A1 (en) * | 2009-07-27 | 2011-06-16 | Meso Scale Technologies, Llc | Assay Apparatuses, Consumables and Methods |
CA3139049A1 (en) | 2010-10-14 | 2012-04-19 | Meso Scale Technologies, Llc | Reagent storage in an assay device |
CN103443614B (zh) | 2010-10-25 | 2015-07-22 | 霍夫曼-拉罗奇有限公司 | 信号增强化合物在电化学发光检测中的用途 |
ES2700792T3 (es) | 2011-11-11 | 2019-02-19 | Eli N Glezer | Procedimientos de ensayo asistidos por coagente de unión |
US9213043B2 (en) | 2012-05-15 | 2015-12-15 | Wellstat Diagnostics, Llc | Clinical diagnostic system including instrument and cartridge |
US9625465B2 (en) | 2012-05-15 | 2017-04-18 | Defined Diagnostics, Llc | Clinical diagnostic systems |
US9081001B2 (en) | 2012-05-15 | 2015-07-14 | Wellstat Diagnostics, Llc | Diagnostic systems and instruments |
CA2896541C (en) | 2013-01-04 | 2020-04-21 | Ian Chamberlin | Assay apparatuses, methods and reagents |
KR20220147717A (ko) | 2013-03-11 | 2022-11-03 | 메소 스케일 테크놀러지즈, 엘엘시 | 다중화 어세이를 수행하기 위한 개선된 방법 |
US10114015B2 (en) | 2013-03-13 | 2018-10-30 | Meso Scale Technologies, Llc. | Assay methods |
KR102257912B1 (ko) | 2013-03-13 | 2021-05-27 | 메소 스케일 테크놀러지즈, 엘엘시 | 개선된 분석 방법 |
KR102134168B1 (ko) | 2013-03-15 | 2020-07-15 | 루브리졸 어드밴스드 머티어리얼스, 인코포레이티드 | 중금속이 없는 씨피브이씨 조성물 |
CA3229509A1 (en) | 2014-05-09 | 2015-11-12 | Meso Scale Technologies, Llc. | Graphene-modified electrodes |
CN112239774A (zh) | 2014-05-15 | 2021-01-19 | 中尺度技术有限责任公司 | 改进的测定方法 |
CN104297231A (zh) * | 2014-10-30 | 2015-01-21 | 中国科学院长春应用化学研究所 | 一种电化学发光光谱仪 |
CN107923911A (zh) | 2015-08-20 | 2018-04-17 | 豪夫迈·罗氏有限公司 | 使用聚乙二醇化分析物特异性结合剂的基于颗粒的免疫测定法 |
BR112018017336A2 (pt) | 2016-03-07 | 2018-12-26 | Hoffmann La Roche | método in vitro para detectar um anticorpo para p53 (anticorpo anti-p53) em uma amostra e polipeptídeo de fusão |
EP3426398B1 (en) | 2016-03-11 | 2024-01-24 | Roche Diagnostics GmbH | Branched-chain amines in electrochemiluminescence detection |
ES2865511T3 (es) | 2017-02-02 | 2021-10-15 | Hoffmann La Roche | Inmunoanálisis que usa al menos dos agentes de unión específica a analito pegilado |
FI127861B (en) | 2017-06-29 | 2019-04-15 | Labmaster Oy | Method and apparatus for dynamically generating hot electrons in aqueous solutions |
EP3756009B1 (en) | 2018-02-23 | 2023-09-06 | Meso Scale Technologies, LLC | Methods of screening antigen-binding molecules by normalizing for the concentration of antigen-binding molecule |
JP2021522192A (ja) | 2018-04-18 | 2021-08-30 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 新規抗チミジンキナーゼ抗体 |
EP3844503B1 (en) | 2018-08-31 | 2024-05-29 | F. Hoffmann-La Roche AG | Thymidine kinase (tk-1) in prognostic indices for dlbcl |
SG11202012634UA (en) * | 2018-12-17 | 2021-01-28 | Illumina Inc | Flow cells and sequencing kits |
CA3125146A1 (en) | 2019-01-03 | 2020-07-09 | Meso Scale Technologies, Llc | Compositions and methods for carrying out assay measurements |
JP2022522480A (ja) | 2019-03-01 | 2022-04-19 | メソ スケール テクノロジーズ エルエルシー | 免疫測定法で使用するための電気化学発光標識プローブ、当該プローブを使用する方法および該プローブを含むキット |
CN113939599A (zh) | 2019-06-07 | 2022-01-14 | 豪夫迈·罗氏有限公司 | 杂交全lna寡核苷酸 |
JP7315781B2 (ja) | 2019-07-22 | 2023-07-26 | エフ. ホフマン-ラ ロシュ アーゲー | 子宮内膜症の非侵襲的診断のための血液バイオマーカーとしてのs100a12 |
WO2021013786A1 (en) | 2019-07-22 | 2021-01-28 | F. Hoffmann-La Roche Ag | S100a6 as blood biomarker for the non-invasive diagnosis of endometriosis |
CN114144674A (zh) | 2019-07-22 | 2022-03-04 | 豪夫迈·罗氏有限公司 | P物质作为用于子宫内膜异位症的非侵入性诊断的血液生物标志物 |
CN114144673A (zh) | 2019-07-22 | 2022-03-04 | 豪夫迈·罗氏有限公司 | S100a8作为血液生物标志物用于子宫内膜异位症的非侵入性诊断 |
EP4004554A1 (en) | 2019-07-22 | 2022-06-01 | F. Hoffmann-La Roche AG | S100a9 as blood biomarker for the non-invasive diagnosis of endometriosis |
CN110501406B (zh) * | 2019-09-30 | 2021-11-19 | 青岛大学 | 一种基于石墨烯电极的亚精胺电化学发光检测法 |
BR112022009371A2 (pt) | 2019-11-15 | 2022-08-09 | Hoffmann La Roche | Métodos para determinar a quantidade ou concentração de um ou mais analitos antibióticos, tubos de amostragem, usos de um reagente de derivatização nucleofílica e analito antibiótico |
WO2021236584A1 (en) | 2020-05-19 | 2021-11-25 | Meso Scale Technologies, Llc. | Methods, compositions, and kits for nucleic acid detection |
AU2021299536A1 (en) | 2020-07-01 | 2023-02-16 | Meso Scale Technologies, Llc. | Compositions and methods for assay measurements |
US20230406909A1 (en) | 2020-11-02 | 2023-12-21 | Roche Diagnostics Operations, Inc. | Sars-cov-2 nucleocapsid antibodies |
JP2023554517A (ja) | 2020-12-22 | 2023-12-27 | エフ. ホフマン-ラ ロシュ アーゲー | 試料中の目的の分析物を検出するための方法 |
WO2022207628A1 (en) | 2021-03-30 | 2022-10-06 | F. Hoffmann-La Roche Ag | Scf as blood biomarker for the non-invasive diagnosis of endometriosis |
CN117099001A (zh) | 2021-04-01 | 2023-11-21 | 豪夫迈·罗氏有限公司 | Psp94作为血液生物标志物用于子宫内膜异位症的非侵入性诊断 |
WO2022243210A1 (en) | 2021-05-17 | 2022-11-24 | F. Hoffmann-La Roche Ag | sFRP4 AS BLOOD BIOMARKER FOR THE NON-INVASIVE DIAGNOSIS OF ADENOMYOSIS |
WO2023278293A1 (en) | 2021-06-28 | 2023-01-05 | Meso Scale Technologies, Llc. | Methods, compositions, and kits for assay signal amplification |
WO2023072904A1 (en) | 2021-10-26 | 2023-05-04 | F. Hoffmann-La Roche Ag | Monoclonal antibodies specific for sars-cov-2 rbd |
US20230279290A1 (en) | 2021-12-30 | 2023-09-07 | Meso Scale Technologies, Llc. | Compositions and methods for assay measurements |
WO2023131594A1 (en) | 2022-01-05 | 2023-07-13 | F. Hoffmann-La Roche Ag | Derivatization of compounds in patient samples for therapeutic drug monitoring (tdm) |
WO2023156510A1 (en) | 2022-02-18 | 2023-08-24 | F. Hoffmann-La Roche Ag | Method for detecting an analyte of interest in a sample |
WO2023196927A1 (en) | 2022-04-07 | 2023-10-12 | Meso Scale Technologies, Llc. | Methods and kits for assessing alzheimer's disease |
WO2023247752A1 (en) | 2022-06-23 | 2023-12-28 | F. Hoffmann-La Roche Ag | Method for diagnosing endometriosis and for classifying the stage of endometriosis |
WO2024017982A1 (en) | 2022-07-22 | 2024-01-25 | F. Hoffmann-La Roche Ag | Leukotriene a4 hydrolase (lta4h) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome |
WO2024017983A1 (en) | 2022-07-22 | 2024-01-25 | F. Hoffmann-La Roche Ag | Meteorin-like protein (metrnl) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome |
WO2024017985A1 (en) | 2022-07-22 | 2024-01-25 | F. Hoffmann-La Roche Ag | Fibroblast growth factor binding protein 1 (fgfbp1) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3442816A (en) * | 1966-02-23 | 1969-05-06 | American Cyanamid Co | Generation of light by the reaction of tetracyanoethylene or other electronegatively substituted ethylene,ethylene oxide and carbonyl compound with hydrogen peroxide in the presence of a fluorescer |
US5310687A (en) * | 1984-10-31 | 1994-05-10 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
US5238808A (en) * | 1984-10-31 | 1993-08-24 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
US5221605A (en) * | 1984-10-31 | 1993-06-22 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
JPH01305069A (ja) * | 1988-05-31 | 1989-12-08 | Shionogi & Co Ltd | ベンゾトリアゾール誘導体およびそれを含有する発螢光試薬 |
US5324457A (en) * | 1989-10-02 | 1994-06-28 | Board Of Regents, The University Of Tx System | Devices and methods for generating electrogenerated chemiluminescence |
US5340714A (en) * | 1992-05-08 | 1994-08-23 | Monitor Diagnostics, Inc. | Use of nonmetallic tetrapyrrole molecules and novel signal solutions in chemiluminescent reactions and assays |
JPH10509025A (ja) * | 1994-08-26 | 1998-09-08 | アイジェン, インコーポレイテッド | 固体表面に吸着された核酸の電気的に発生した化学ルミネッセンス性検出のためのバイオセンサーおよび方法 |
-
1995
- 1995-02-09 US US08/385,864 patent/US5786141A/en not_active Expired - Lifetime
-
1996
- 1996-02-09 EP EP96903716A patent/EP0755458B1/en not_active Expired - Lifetime
- 1996-02-09 AT AT96903716T patent/ATE274601T1/de active
- 1996-02-09 DE DE69633212T patent/DE69633212T2/de not_active Expired - Lifetime
- 1996-02-09 PT PT96903716T patent/PT755458E/pt unknown
- 1996-02-09 CA CA002186503A patent/CA2186503C/en not_active Expired - Lifetime
- 1996-02-09 JP JP52429396A patent/JP3989019B2/ja not_active Expired - Lifetime
- 1996-02-09 AU AU47708/96A patent/AU709592B2/en not_active Expired
- 1996-02-09 ES ES96903716T patent/ES2227580T3/es not_active Expired - Lifetime
- 1996-02-09 DK DK96903716T patent/DK0755458T3/da active
- 1996-02-09 WO PCT/US1996/001113 patent/WO1996024690A1/en active IP Right Grant
-
1998
- 1998-05-20 US US09/082,273 patent/US6479233B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP3989019B2 (ja) | 2007-10-10 |
US6479233B1 (en) | 2002-11-12 |
DE69633212D1 (de) | 2004-09-30 |
DE69633212T2 (de) | 2005-09-22 |
DK0755458T3 (da) | 2004-11-29 |
AU4770896A (en) | 1996-08-27 |
CA2186503A1 (en) | 1996-08-15 |
EP0755458B1 (en) | 2004-08-25 |
EP0755458A4 (en) | 2000-07-26 |
ES2227580T3 (es) | 2005-04-01 |
ATE274601T1 (de) | 2004-09-15 |
AU709592B2 (en) | 1999-09-02 |
WO1996024690A1 (en) | 1996-08-15 |
CA2186503C (en) | 2007-01-23 |
EP0755458A1 (en) | 1997-01-29 |
JPH10502702A (ja) | 1998-03-10 |
US5786141A (en) | 1998-07-28 |
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