US1776008A
(en)
|
1929-07-24 |
1930-09-16 |
James H Plater |
Piston-ring expander
|
CA1293460C
(en)
|
1985-10-07 |
1991-12-24 |
Brian Lee Sauer |
Site-specific recombination of dna in yeast
|
US4833080A
(en)
|
1985-12-12 |
1989-05-23 |
President And Fellows Of Harvard College |
Regulation of eucaryotic gene expression
|
US6022742A
(en)
|
1986-11-26 |
2000-02-08 |
Kopf; Henry B. |
Culture device and method
|
US6689610B1
(en)
|
1989-08-22 |
2004-02-10 |
University Of Utah Research Foundation |
Cells and non-human organisms containing predetermined genomic modifications and positive-negative selection methods and vectors for making same
|
US5464764A
(en)
|
1989-08-22 |
1995-11-07 |
University Of Utah Research Foundation |
Positive-negative selection methods and vectors
|
KR100236506B1
(ko)
|
1990-11-29 |
2000-01-15 |
퍼킨-엘머시터스인스트루먼츠 |
폴리머라제 연쇄 반응 수행 장치
|
WO1992015694A1
(en)
|
1991-03-08 |
1992-09-17 |
The Salk Institute For Biological Studies |
Flp-mediated gene modification in mammalian cells, and compositions and cells useful therefor
|
US6074605A
(en)
|
1995-03-10 |
2000-06-13 |
Entremed, Inc. |
Flow electroporation chamber and method
|
AU724922B2
(en)
|
1995-06-07 |
2000-10-05 |
Invitrogen Corporation |
Recombinational cloning using engineered recombination sites
|
US5851804A
(en)
|
1996-05-06 |
1998-12-22 |
Apollon, Inc. |
Chimeric kanamycin resistance gene
|
US5792943A
(en)
|
1997-04-30 |
1998-08-11 |
Hewlett-Packard Company |
Planar separation column for use in sample analysis system
|
US6774279B2
(en)
|
1997-05-30 |
2004-08-10 |
Carnegie Institution Of Washington |
Use of FLP recombinase in mice
|
CA2307016A1
(en)
|
1997-10-24 |
1999-05-06 |
Life Technologies, Inc. |
Recombinational cloning using nucleic acids having recombination sites
|
CA2312474C
(en)
|
1997-12-05 |
2012-07-03 |
Europaisches Laboratorium Fur Molekularbiologie |
Novel dna cloning method
|
US6027488A
(en)
|
1998-06-03 |
2000-02-22 |
Genetronics, Inc. |
Flow-through electroporation system for ex vivo gene therapy
|
US6697669B2
(en)
|
1998-07-13 |
2004-02-24 |
Genetronics, Inc. |
Skin and muscle-targeted gene therapy by pulsed electrical field
|
US6391582B2
(en)
|
1998-08-14 |
2002-05-21 |
Rigel Pharmaceuticlas, Inc. |
Shuttle vectors
|
US6150148A
(en)
|
1998-10-21 |
2000-11-21 |
Genetronics, Inc. |
Electroporation apparatus for control of temperature during the process
|
DE19859459A1
(de)
*
|
1998-12-22 |
2000-06-29 |
Evotec Biosystems Ag |
Mikrosysteme zur Zellpermeation und Zellfusion
|
EP1147209A2
(en)
|
1999-02-03 |
2001-10-24 |
The Children's Medical Center Corporation |
Gene repair involving the induction of double-stranded dna cleavage at a chromosomal target site
|
SE9900530D0
(sv)
|
1999-02-15 |
1999-02-15 |
Vincenzo Vassarotti |
A device for concentrating and/or purifying macromolecules in a solution and a method for manufacturing such a device
|
US6678558B1
(en)
|
1999-03-25 |
2004-01-13 |
Genetronics, Inc. |
Method and apparatus for reducing electroporation-mediated muscle reaction and pain response
|
US6818185B1
(en)
|
1999-05-28 |
2004-11-16 |
Cepheid |
Cartridge for conducting a chemical reaction
|
DK1181098T4
(da)
*
|
1999-05-28 |
2011-09-26 |
Cepheid |
Patron til udførelse af en kemisk reaktion
|
US6300108B1
(en)
|
1999-07-21 |
2001-10-09 |
The Regents Of The University Of California |
Controlled electroporation and mass transfer across cell membranes
|
US6986993B1
(en)
|
1999-08-05 |
2006-01-17 |
Cellomics, Inc. |
System for cell-based screening
|
WO2002010183A1
(en)
|
2000-07-31 |
2002-02-07 |
Menzel, Rolf |
Compositions and methods for directed gene assembly
|
EP1313851B1
(en)
|
2000-08-21 |
2006-01-04 |
Invitrogen Corporation |
Methods and reagents for molecular cloning
|
FR2814642B1
(fr)
|
2000-10-03 |
2005-07-01 |
Ass Pour Le Dev De La Rech En |
Souris transgenique pour la recombinaison ciblee mediee par la cre-er modifiee
|
US7029916B2
(en)
|
2001-02-21 |
2006-04-18 |
Maxcyte, Inc. |
Apparatus and method for flow electroporation of biological samples
|
US20020139741A1
(en)
|
2001-03-27 |
2002-10-03 |
Henry Kopf |
Integral gasketed filtration cassette article and method of making the same
|
WO2003018751A2
(en)
|
2001-08-22 |
2003-03-06 |
Maxcyte, Inc. |
Apparatus and method for electroporation of biological samples
|
US7166443B2
(en)
|
2001-10-11 |
2007-01-23 |
Aviva Biosciences Corporation |
Methods, compositions, and automated systems for separating rare cells from fluid samples
|
TWI229696B
(en)
*
|
2001-11-09 |
2005-03-21 |
Yeastern Biotech Co Ltd |
A fast method of transforming competent cells
|
US7018819B2
(en)
|
2001-11-30 |
2006-03-28 |
Cellectricon Ab |
Method and apparatus for manipulation of cells and cell-like structures focused electric fields in microfludic systems and use thereof
|
WO2003057819A1
(en)
|
2002-01-07 |
2003-07-17 |
Uab Research Foundation |
Electroporation cuvette-pipette tips, multi-well cuvette arrays, and electrode template apparatus adapted for automation and uses thereof
|
CA2474486C
(en)
|
2002-01-23 |
2013-05-14 |
The University Of Utah Research Foundation |
Targeted chromosomal mutagenesis using zinc finger nucleases
|
BRPI0310060B8
(pt)
*
|
2002-05-17 |
2021-07-27 |
Becton Dickinson Co |
sistema automatizado para isolar, amplificar e detectar uma seqüência de ácido nucléico alvo ou uma proteína
|
CA2391641A1
(fr)
|
2002-06-28 |
2003-12-28 |
Robert Longin |
Plateforme robotisee de cultures cellulaires en batteries de reacteurs miniaturises, equipee d'un systeme de mesure en temps reel de la turbidite cellulaire ou toutes autres proprietes optiques
|
CA2534874A1
(en)
|
2002-08-13 |
2004-02-19 |
National Jewish Medical And Research Center |
Method for identifying mhc-presented peptide epitopes for t cells
|
CA2497649A1
(en)
|
2002-09-30 |
2004-04-15 |
Maxcyte, Inc. |
Apparatus and method for streaming electroporation
|
US20040138154A1
(en)
|
2003-01-13 |
2004-07-15 |
Lei Yu |
Solid surface for biomolecule delivery and high-throughput assay
|
EP1516920A1
(en)
|
2003-09-19 |
2005-03-23 |
The Automation Partnership |
Cell culture vessel for the automated processing of cell cultures
|
US20050118705A1
(en)
|
2003-11-07 |
2005-06-02 |
Rabbitt Richard D. |
Electrical detectors for microanalysis
|
US7078227B2
(en)
|
2004-03-26 |
2006-07-18 |
Molecular Transfer |
Ready-to-use electroporation cuvette including frozen electrocompetent cells
|
CN101426929B
(zh)
|
2004-05-12 |
2011-06-08 |
麦克赛特股份有限公司 |
与可调流式电穿孔室相关的方法和装置
|
US8932850B2
(en)
|
2004-06-12 |
2015-01-13 |
Invitrogen Singapore Pte. Ltd. |
Electroporation apparatus having an elongated hollow member
|
US7422889B2
(en)
|
2004-10-29 |
2008-09-09 |
Stowers Institute For Medical Research |
Dre recombinase and recombinase systems employing Dre recombinase
|
CA2601704A1
(en)
*
|
2005-03-22 |
2006-09-28 |
Irm Llc |
Compound profiling devices, systems, and related methods
|
WO2006130299A2
(en)
|
2005-05-03 |
2006-12-07 |
Micronics, Inc. |
Microfluidic laminar flow detection strip
|
DK2336362T3
(en)
|
2005-08-26 |
2019-01-21 |
Dupont Nutrition Biosci Aps |
USE OF CRISPR-ASSOCIATED GENES (CAS)
|
US20070105206A1
(en)
|
2005-10-19 |
2007-05-10 |
Chang Lu |
Fluidic device
|
US20110189650A1
(en)
|
2010-02-03 |
2011-08-04 |
Ayliffe Harold E |
Microfluidic cell sorter with electroporation
|
US7923238B2
(en)
|
2006-02-10 |
2011-04-12 |
Bio-Rad Laboratories, Inc. |
Multi-channel electroporation system
|
US7799555B2
(en)
|
2006-02-10 |
2010-09-21 |
Bio-Rad Laboratories, Inc. |
Apparatus for high-throughput electroporation
|
WO2008052101A2
(en)
|
2006-10-25 |
2008-05-02 |
President And Fellows Of Harvard College |
Multiplex automated genome engineering
|
US8486692B2
(en)
|
2006-11-14 |
2013-07-16 |
Acme Biosystems Llc |
Cell culture apparatus and associated methods
|
US8748146B2
(en)
|
2007-04-19 |
2014-06-10 |
Celexion, Llc |
Engineered nucleases and their uses for nucleic acid assembly
|
US20110213288A1
(en)
|
2007-04-23 |
2011-09-01 |
The Board Of Regents, The University Of Texas System |
Device And Method For Transfecting Cells For Therapeutic Uses
|
WO2009025690A2
(en)
|
2007-05-23 |
2009-02-26 |
Nature Technology Corporation |
Improved e. coli plasmid dna production
|
US8110112B2
(en)
|
2007-05-30 |
2012-02-07 |
Innova Prep LLC |
Liquid to liquid biological particle concentrator
|
US8470266B2
(en)
|
2007-09-10 |
2013-06-25 |
Nec Corporation |
Sample packing device
|
GB0724860D0
(en)
|
2007-12-20 |
2008-01-30 |
Heptares Therapeutics Ltd |
Screening
|
EP4328297A2
(en)
|
2008-01-17 |
2024-02-28 |
Inovio Pharmaceuticals, Inc. |
Variable current density single needle electroporation system and method
|
US8450112B2
(en)
|
2008-04-09 |
2013-05-28 |
Maxcyte, Inc. |
Engineering and delivery of therapeutic compositions of freshly isolated cells
|
US9845455B2
(en)
|
2008-05-15 |
2017-12-19 |
Ge Healthcare Bio-Sciences Ab |
Method for cell expansion
|
DE102008025968B4
(de)
|
2008-05-30 |
2014-08-21 |
Sartorius Stedim Biotech Gmbh |
Bioreaktor mit Kondensator
|
ATE496639T1
(de)
|
2008-06-19 |
2011-02-15 |
Eppendorf Array Tech Sa |
Streifen für multiparametrische assays
|
JP5459903B2
(ja)
|
2008-09-02 |
2014-04-02 |
株式会社半導体エネルギー研究所 |
アントラセン誘導体、発光素子、発光装置、電子機器、及び照明装置
|
US20100076057A1
(en)
|
2008-09-23 |
2010-03-25 |
Northwestern University |
TARGET DNA INTERFERENCE WITH crRNA
|
EA027693B1
(ru)
|
2008-09-26 |
2017-08-31 |
Токаджен Инк. |
Рекомбинантный репликационно-компетентный ретровирус с цитозиндезаминазной активностью для генной терапии нарушений клеточной пролиферации
|
KR101156886B1
(ko)
|
2008-11-04 |
2012-06-21 |
웅진코웨이주식회사 |
수위감지장치
|
WO2010059763A1
(en)
|
2008-11-19 |
2010-05-27 |
Amyris Biotechnologies, Inc. |
Compositions and methods for the assembly of polynucleotides
|
EP2206723A1
(en)
|
2009-01-12 |
2010-07-14 |
Bonas, Ulla |
Modular DNA-binding domains
|
EP2216395A1
(en)
|
2009-02-09 |
2010-08-11 |
Lonza Biologics plc. |
Bioreactor for the cultivation of mammalian cells
|
WO2010093966A2
(en)
|
2009-02-12 |
2010-08-19 |
Fred Hutchinson Cancer Research Center |
Generation of a dna nicking enzyme that stimulates site-specific gene conversion from a homing endonuclease
|
CN102713640B
(zh)
|
2009-06-10 |
2015-09-16 |
辛温尼奥生物系统公司 |
鞘流装置和方法
|
US8677840B2
(en)
|
2009-06-12 |
2014-03-25 |
Innovaprep Llc |
Surface sampler for bioterrorism particle detection
|
US9234016B2
(en)
|
2009-07-28 |
2016-01-12 |
Sangamo Biosciences, Inc. |
Engineered zinc finger proteins for treating trinucleotide repeat disorders
|
RU95663U1
(ru)
*
|
2009-07-29 |
2010-07-10 |
Федеральное агентство по науке и инновациям (Роснаука) |
Устройство для культивирования клеток
|
US9063136B2
(en)
|
2009-08-02 |
2015-06-23 |
Qvella Corporation |
Cell concentration, capture and lysis devices and methods of use thereof
|
US8584535B2
(en)
|
2009-09-17 |
2013-11-19 |
Innova Prep LLC |
Liquid to liquid biological particle concentrator with disposable fluid path
|
US8584536B2
(en)
|
2009-09-21 |
2013-11-19 |
Innovaprep Llc |
Devices, systems and methods for elution of particles from flat filters
|
GB0922434D0
(en)
|
2009-12-22 |
2010-02-03 |
Ucb Pharma Sa |
antibodies and fragments thereof
|
US9101883B2
(en)
|
2009-11-28 |
2015-08-11 |
Smartflow Technologies, Inc. |
Portable filtration unit
|
SG181601A1
(en)
|
2009-12-10 |
2012-07-30 |
Univ Minnesota |
Tal effector-mediated dna modification
|
DE102010001779A1
(de)
|
2010-02-10 |
2011-08-11 |
Hamilton Bonaduz Ag |
Kalibrierbare Sensoreinheit für Reaktionsbehälter
|
US8726744B2
(en)
|
2010-02-16 |
2014-05-20 |
Innovaprep Llc |
Portable concentrator
|
DE202010012382U1
(de)
|
2010-04-14 |
2010-12-02 |
Gassmann, Urs |
Dicht- und Montageband
|
SG185481A1
(en)
|
2010-05-10 |
2012-12-28 |
Univ California |
Endoribonuclease compositions and methods of use thereof
|
KR20130086301A
(ko)
|
2010-06-03 |
2013-08-01 |
더 리젠츠 오브 더 유니버시티 오브 캘리포니아 |
전기천공 전극 구성 및 방법
|
EP2395087A1
(en)
|
2010-06-11 |
2011-12-14 |
Icon Genetics GmbH |
System and method of modular cloning
|
EP2743704A3
(en)
|
2010-07-23 |
2014-06-25 |
Beckman Coulter, Inc. |
System or method of including analytical units
|
WO2012048275A2
(en)
|
2010-10-08 |
2012-04-12 |
Caridianbct, Inc. |
Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
|
US9361427B2
(en)
|
2011-02-01 |
2016-06-07 |
The Regents Of The University Of California |
Scar-less multi-part DNA assembly design automation
|
US8667839B2
(en)
|
2011-02-18 |
2014-03-11 |
Tohoku Gakuin |
Heat conduction-type sensor for calibrating effects of temperature and type of fluid, and thermal flow sensor and thermal barometric sensor using this sensor
|
CA2834375C
(en)
|
2011-04-27 |
2020-07-14 |
Amyris, Inc. |
Methods for genomic modification
|
DE102011106162B3
(de)
|
2011-06-30 |
2012-09-13 |
Sartorius Stedim Biotech Gmbh |
Bioreaktorbehälter und Integritätsprüfungsverfahren für Bioreaktorbehälter
|
US9382510B2
(en)
|
2011-08-25 |
2016-07-05 |
Jian Chen |
Methods and devices for electroporation
|
US8332160B1
(en)
|
2011-11-17 |
2012-12-11 |
Amyris Biotechnologies, Inc. |
Systems and methods for engineering nucleic acid constructs using scoring techniques
|
KR102039202B1
(ko)
*
|
2011-12-01 |
2019-10-31 |
뉴욕 스템 셀 파운데이션, 인코포레이티드 |
유도 다능성 줄기 세포 또는 분화된 세포를 제조하기 위한 자동화 시스템
|
DK3260140T3
(da)
*
|
2011-12-05 |
2021-04-19 |
Factor Bioscience Inc |
Fremgangsmåder og produkter til transficering af celler
|
ITCO20120004A1
(it)
|
2012-02-07 |
2013-08-08 |
Giuseppe Caccia |
Apparecchio per elettroporazzione dinamica vaginale e anale
|
JP6490426B2
(ja)
|
2012-02-29 |
2019-03-27 |
サンガモ セラピューティクス, インコーポレイテッド |
ハンチントン病を治療するための方法および組成物
|
US9637739B2
(en)
|
2012-03-20 |
2017-05-02 |
Vilnius University |
RNA-directed DNA cleavage by the Cas9-crRNA complex
|
EP2831221A1
(en)
|
2012-03-29 |
2015-02-04 |
The Arizona Board Of Regents On Behalf Of The University of Arizona |
Cell culture apparatus and culture methods using same
|
LT3401400T
(lt)
|
2012-05-25 |
2019-06-10 |
The Regents Of The University Of California |
Būdai ir kompozicijos, skirtos rnr molekulės nukreipiamai tikslinės dnr modifikacijai ir rnr molekulės nukreipiamam transkripcijos moduliavimui
|
JP6509727B2
(ja)
*
|
2012-06-25 |
2019-05-15 |
ギンゴー バイオワークス, インコーポレイテッド |
核酸アセンブリおよび高処理シークエンシングのための方法
|
PL2877490T3
(pl)
|
2012-06-27 |
2019-03-29 |
The Trustees Of Princeton University |
Inteiny podzielone, koniugaty i ich zastosowania
|
PT3494997T
(pt)
|
2012-07-25 |
2019-12-05 |
Massachusetts Inst Technology |
Proteínas de ligação a adn indutíveis e ferramentas de perturbação do genoma e aplicações destas
|
US9718060B2
(en)
*
|
2012-08-16 |
2017-08-01 |
Synthetic Genomics, Inc. |
Digital to biological converter
|
US9175259B2
(en)
|
2012-08-20 |
2015-11-03 |
Terumo Bct, Inc. |
Method of loading and distributing cells in a bioreactor of a cell expansion system
|
US9020605B2
(en)
|
2012-10-25 |
2015-04-28 |
Oncosec Medical Incorporated |
Electroporation device
|
US9846157B2
(en)
*
|
2012-10-26 |
2017-12-19 |
The Trustees Of The University Of Pennsylvania |
Compositions, methods and microfluidics device for telomerase based in vitro diagnostic assays for detecting circulating tumor cells (CTC)
|
EP3138911B1
(en)
|
2012-12-06 |
2018-12-05 |
Sigma Aldrich Co. LLC |
Crispr-based genome modification and regulation
|
US8697359B1
(en)
|
2012-12-12 |
2014-04-15 |
The Broad Institute, Inc. |
CRISPR-Cas systems and methods for altering expression of gene products
|
USD731634S1
(en)
|
2012-12-31 |
2015-06-09 |
Innovaprep Llc |
Aerosol filter and extraction cap
|
US10612043B2
(en)
|
2013-03-09 |
2020-04-07 |
Agilent Technologies, Inc. |
Methods of in vivo engineering of large sequences using multiple CRISPR/cas selections of recombineering events
|
AU2013202805B2
(en)
*
|
2013-03-14 |
2015-07-16 |
Gen-Probe Incorporated |
System and method for extending the capabilities of a diagnostic analyzer
|
US9499855B2
(en)
|
2013-03-14 |
2016-11-22 |
Elwha Llc |
Compositions, methods, and computer systems related to making and administering modified T cells
|
US9816088B2
(en)
|
2013-03-15 |
2017-11-14 |
Abvitro Llc |
Single cell bar-coding for antibody discovery
|
US9234213B2
(en)
|
2013-03-15 |
2016-01-12 |
System Biosciences, Llc |
Compositions and methods directed to CRISPR/Cas genomic engineering systems
|
EP4286517A3
(en)
|
2013-04-04 |
2024-03-13 |
President and Fellows of Harvard College |
Therapeutic uses of genome editing with crispr/cas systems
|
EP3004349B1
(en)
|
2013-05-29 |
2018-03-28 |
Cellectis S.A. |
A method for producing precise dna cleavage using cas9 nickase activity
|
CN105339076B
(zh)
|
2013-06-25 |
2018-11-23 |
利乐拉瓦尔集团及财务有限公司 |
具有卫生悬挂装置的膜过滤设备
|
IL243475B2
(en)
|
2013-07-09 |
2023-11-01 |
Harvard College |
Multiplex RNA-guided genome engineering
|
US9029109B2
(en)
|
2013-08-07 |
2015-05-12 |
President And Fellows Of Harvard College |
Microfluidic vortex-assisted electroporation system and method
|
US9322037B2
(en)
|
2013-09-06 |
2016-04-26 |
President And Fellows Of Harvard College |
Cas9-FokI fusion proteins and uses thereof
|
US10822606B2
(en)
|
2013-09-27 |
2020-11-03 |
The Regents Of The University Of California |
Optimized small guide RNAs and methods of use
|
US20150098954A1
(en)
|
2013-10-08 |
2015-04-09 |
Elwha Llc |
Compositions and Methods Related to CRISPR Targeting
|
US10767156B2
(en)
|
2013-10-24 |
2020-09-08 |
Yeda Research And Development Co., Ltd. |
Polynucleotides encoding BREX system polypeptides and methods of using same
|
CN103555574A
(zh)
|
2013-11-11 |
2014-02-05 |
苏州文曲生物微系统有限公司 |
一种流式电穿孔装置
|
JP6633522B2
(ja)
|
2013-11-16 |
2020-01-22 |
テルモ ビーシーティー、インコーポレーテッド |
バイオリアクターにおける細胞増殖
|
RU2685914C1
(ru)
|
2013-12-11 |
2019-04-23 |
Регенерон Фармасьютикалс, Инк. |
Способы и композиции для направленной модификации генома
|
WO2015089354A1
(en)
|
2013-12-12 |
2015-06-18 |
The Broad Institute Inc. |
Compositions and methods of use of crispr-cas systems in nucleotide repeat disorders
|
DE102013114732A1
(de)
|
2013-12-20 |
2015-06-25 |
Hamilton Bonaduz Ag |
Abdeckvorrichtung, insbesondere Deckel für die Abdeckung von Reaktionsgefäßen
|
US11119093B2
(en)
|
2013-12-20 |
2021-09-14 |
President And Fellows Of Harvard College |
Low shear microfluidic devices and methods of use and manufacturing thereof
|
KR101598847B1
(ko)
*
|
2014-01-23 |
2016-03-02 |
부경대학교 산학협력단 |
액적의 직접 충전 및 전기영동에 기반한 전기천공 기기, 장치 및 방법
|
US10787654B2
(en)
|
2014-01-24 |
2020-09-29 |
North Carolina State University |
Methods and compositions for sequence guiding Cas9 targeting
|
CN106164271B
(zh)
|
2014-02-11 |
2020-06-02 |
科罗拉多州立大学董事会(法人团体) |
Crispr支持的多路基因组工程化
|
CA2943569C
(en)
|
2014-03-27 |
2021-02-23 |
British Columbia Cancer Agency Branch |
T-cell epitope identification
|
EP3126503A1
(en)
|
2014-04-03 |
2017-02-08 |
Massachusetts Institute Of Technology |
Methods and compositions for the production of guide rna
|
SG11201608503UA
(en)
*
|
2014-04-14 |
2016-11-29 |
Maxcyte Inc |
Methods and compositions for modifying genomic dna
|
CA2947426C
(en)
|
2014-04-29 |
2020-01-07 |
Illumina, Inc. |
Multiplexed single cell gene expression analysis using template switch and tagmentation
|
KR101886381B1
(ko)
|
2014-05-28 |
2018-08-10 |
기초과학연구원 |
불활성화된 표적 특이적 뉴클레아제를 이용한 표적 dna의 분리 방법
|
WO2016003485A1
(en)
|
2014-07-03 |
2016-01-07 |
Massachusetts Institute Of Technology |
Microfluidic assay for rapid optimization of cell electroporation
|
US20160053304A1
(en)
|
2014-07-18 |
2016-02-25 |
Whitehead Institute For Biomedical Research |
Methods Of Depleting Target Sequences Using CRISPR
|
US20160053272A1
(en)
|
2014-07-18 |
2016-02-25 |
Whitehead Institute For Biomedical Research |
Methods Of Modifying A Sequence Using CRISPR
|
GB201415329D0
(en)
*
|
2014-07-21 |
2014-10-15 |
Ge Healthcare Bio Sciences |
Parallel cell processing method and facility
|
WO2016014429A1
(en)
|
2014-07-21 |
2016-01-28 |
Beckman Coulter, Inc. |
Methods and systems for tube inspection and liquid level detection
|
EP3172314A4
(en)
|
2014-07-25 |
2018-04-18 |
Novogy Inc. |
Promoters derived from yarrowia lipolytica and arxula adeninivorans, and methods of use thereof
|
US20160076093A1
(en)
|
2014-08-04 |
2016-03-17 |
University Of Washington |
Multiplex homology-directed repair
|
EP3204513A2
(en)
|
2014-10-09 |
2017-08-16 |
Life Technologies Corporation |
Crispr oligonucleotides and gene editing
|
CN104263646A
(zh)
|
2014-10-10 |
2015-01-07 |
国家开发投资公司 |
一种微藻光生物反应器用管子
|
WO2016061481A1
(en)
|
2014-10-17 |
2016-04-21 |
The Penn State Research Foundation |
Methods and compositions for multiplex rna guided genome editing and other rna technologies
|
KR102428463B1
(ko)
|
2014-12-28 |
2022-08-03 |
주식회사 펨토바이오메드 |
세포에 물질을 주입하는 장치 및 제조 방법
|
WO2016110453A1
(en)
|
2015-01-06 |
2016-07-14 |
Dsm Ip Assets B.V. |
A crispr-cas system for a filamentous fungal host cell
|
AU2015376652B2
(en)
|
2015-01-07 |
2017-11-30 |
Indee. Inc. |
A method for mechanical and hydrodynamic microfluidic transfection and apparatus therefor
|
WO2016118780A1
(en)
*
|
2015-01-21 |
2016-07-28 |
Fred Hutchinson Cancer Research Center |
Point-of-care and/or portable platform for gene therapy
|
WO2016145416A2
(en)
|
2015-03-11 |
2016-09-15 |
The Broad Institute, Inc. |
Proteomic analysis with nucleic acid identifiers
|
US10954483B2
(en)
*
|
2015-03-12 |
2021-03-23 |
The Trustees Of The University Of Pennsylvania |
System, method, and device for high-throughput, automated culturing of genetically modified organisms
|
KR20170126500A
(ko)
|
2015-03-16 |
2017-11-17 |
막스-델부뤽-센트럼 퓌어 몰레쿨라레 메디친 인 데어 헬름홀츠-게마인샤프트 |
Mhc 세포 라이브러리를 이용하여 신규한 면역원성 t 세포 에피토프를 검출하고 신규한 항원-특이적 t 세포 수용체를 단리하는 방법
|
KR20170135966A
(ko)
|
2015-04-13 |
2017-12-08 |
맥스시티 인코포레이티드 |
게놈 dna를 변형시키기 위한 방법 및 조성물
|
US20180023045A1
(en)
|
2015-04-21 |
2018-01-25 |
General Automation Lab Technologies, Inc. |
High resolution systems, kits, apparatus, and methods using combinatorial media strategies for high throughput microbiology applications
|
US10677793B2
(en)
|
2015-04-21 |
2020-06-09 |
General Automation Lab Technologies Inc. |
High resolution systems, kits, apparatus, and methods using lateral flow for high throughput microbiology applications
|
JP6837473B2
(ja)
|
2015-04-21 |
2021-03-03 |
ジェネラル オートメーション ラボ テクノロジーズ インコーポレイテッド |
ハイスループット微生物学適用高分解能システム、キット、装置、並びに方法
|
LU92752B1
(en)
|
2015-06-24 |
2016-08-07 |
Université Du Luxembourg |
Cell culture apparatus and culture methods using same
|
US9790490B2
(en)
|
2015-06-18 |
2017-10-17 |
The Broad Institute Inc. |
CRISPR enzymes and systems
|
CN115058395A
(zh)
|
2015-06-25 |
2022-09-16 |
美商生物细胞基因治疗有限公司 |
嵌合抗原受体(car)、组合物及其使用方法
|
EP3322797B1
(en)
|
2015-07-13 |
2023-11-29 |
Institut Pasteur |
Improving sequence-specific antimicrobials by blocking dna repair
|
EP3138920B1
(en)
|
2015-09-07 |
2018-06-13 |
Miltenyi Biotec GmbH |
Disposable cartridge for electroporation
|
US11261439B2
(en)
*
|
2015-09-18 |
2022-03-01 |
President And Fellows Of Harvard College |
Methods of making guide RNA
|
CN108369230B
(zh)
|
2015-09-25 |
2021-09-17 |
阿布维特罗有限责任公司 |
用于对天然配对t细胞受体序列进行t细胞受体靶向鉴别的高通量方法
|
US11092607B2
(en)
|
2015-10-28 |
2021-08-17 |
The Board Institute, Inc. |
Multiplex analysis of single cell constituents
|
WO2017075294A1
(en)
|
2015-10-28 |
2017-05-04 |
The Board Institute Inc. |
Assays for massively combinatorial perturbation profiling and cellular circuit reconstruction
|
SG11201803151PA
(en)
|
2015-11-05 |
2018-05-30 |
Agency Science Tech & Res |
Chemical-inducible genome engineering technology
|
EP3374494A4
(en)
|
2015-11-11 |
2019-05-01 |
Coda Biotherapeutics, Inc. |
CRISPR COMPOSITIONS AND METHODS OF USE FOR GENE THERAPY
|
US9988624B2
(en)
|
2015-12-07 |
2018-06-05 |
Zymergen Inc. |
Microbial strain improvement by a HTP genomic engineering platform
|
KR102006320B1
(ko)
*
|
2015-12-07 |
2019-08-02 |
지머젠 인코포레이티드 |
Htp 게놈 공학 플랫폼에 의한 미생물 균주 개량
|
US11151497B2
(en)
|
2016-04-27 |
2021-10-19 |
Zymergen Inc. |
Microbial strain design system and methods for improved large-scale production of engineered nucleotide sequences
|
WO2017106414A1
(en)
|
2015-12-18 |
2017-06-22 |
Danisco Us Inc. |
Methods and compositions for polymerase ii (pol-ii) based guide rna expression
|
US20190017072A1
(en)
|
2016-01-12 |
2019-01-17 |
Sqz Biotechnologies Company |
Intracellular delivery of complexes
|
EP3199632A1
(en)
|
2016-01-26 |
2017-08-02 |
ACIB GmbH |
Temperature-inducible crispr/cas system
|
US9896696B2
(en)
|
2016-02-15 |
2018-02-20 |
Benson Hill Biosystems, Inc. |
Compositions and methods for modifying genomes
|
CN109922885B
(zh)
*
|
2016-03-16 |
2022-05-10 |
伯克利之光生命科技公司 |
用于基因组编辑克隆的选择和传代的方法、系统和装置
|
CN109154614B
(zh)
|
2016-03-18 |
2022-01-28 |
四方控股公司 |
用于细胞分离的组合物、装置和方法
|
KR20180132705A
(ko)
|
2016-04-04 |
2018-12-12 |
에테하 취리히 |
단백질 생산 및 라이브러리(Library) 생성을 위한 포유동물 세포주
|
EP3440186A4
(en)
|
2016-04-04 |
2019-12-11 |
Cytequest, Inc. |
SYSTEM, APPARATUS AND METHOD FOR THE ELECTROPORATION OF CELLS
|
JP7148494B2
(ja)
|
2016-04-25 |
2022-10-05 |
ウニベルシテート バーゼル |
アレル編集およびその応用
|
JP2019517788A
(ja)
|
2016-05-06 |
2019-06-27 |
ジュノー セラピューティクス インコーポレイテッド |
遺伝子操作された細胞および同細胞を作製する方法
|
WO2017210334A1
(en)
|
2016-05-31 |
2017-12-07 |
Massachusetts Institute Of Technology |
Hydrodynamically controlled electric fields for high throughput transformation & high throughput parallel transformation platform
|
EP3907286A1
(en)
|
2016-06-02 |
2021-11-10 |
Sigma-Aldrich Co., LLC |
Using programmable dna binding proteins to enhance targeted genome modification
|
BR112018074889A2
(pt)
|
2016-06-03 |
2019-03-06 |
Lonza Ag |
biorreator de uso único
|
WO2017212400A2
(en)
|
2016-06-06 |
2017-12-14 |
The University Of Chicago |
Proximity-dependent split rna polymerases as a versatile biosensor platform
|
JP2019522481A
(ja)
|
2016-06-22 |
2019-08-15 |
アイカーン スクール オブ メディシン アット マウント サイナイ |
自己切断リボザイムを利用したrnaのウイルス送達およびそのcrisprベースの適用
|
AU2017280353B2
(en)
|
2016-06-24 |
2021-11-11 |
Inscripta, Inc. |
Methods for generating barcoded combinatorial libraries
|
KR20220130248A
(ko)
|
2016-06-24 |
2022-09-26 |
론자 리미티드 |
가변 직경 생물 반응기
|
JP2019521715A
(ja)
*
|
2016-07-21 |
2019-08-08 |
セリアドCelyad |
細胞を自動的に独立並列してバッチ処理するための方法および装置
|
WO2018015419A1
(de)
|
2016-07-22 |
2018-01-25 |
Tecan Trading Ag |
Pipettenspitze für eine automatisierte pipettiervorrichtung sowie verfahren zu deren herstellung
|
US20190264193A1
(en)
|
2016-08-12 |
2019-08-29 |
Caribou Biosciences, Inc. |
Protein engineering methods
|
DE102016115403A1
(de)
|
2016-08-19 |
2018-02-22 |
Hamilton Bonaduz Ag |
Autonome Vorrichtung zum Erfassen von Eigenschaften eines Messmediums und Verfahren dafür
|
WO2017216392A1
(en)
|
2016-09-23 |
2017-12-21 |
Dsm Ip Assets B.V. |
A guide-rna expression system for a host cell
|
WO2018071672A1
(en)
|
2016-10-12 |
2018-04-19 |
The Regents Of The University Of Colorado |
Novel engineered and chimeric nucleases
|
WO2018073391A1
(en)
|
2016-10-19 |
2018-04-26 |
Cellectis |
Targeted gene insertion for improved immune cells therapy
|
FI3535290T3
(fi)
|
2016-11-07 |
2024-02-05 |
Genovie Ab |
Keinotekoinen kaksiosainen solulaite T-solun reseptorin vuorovaikutuksen havaitsemiseksi ja luonnehtimiseksi kognaattiantigeenin kanssa
|
EP3545074A1
(en)
|
2016-11-23 |
2019-10-02 |
The Charles Stark Draper Laboratory Inc. |
Bi-layer multi-well cell culture platform
|
US20180179485A1
(en)
|
2016-12-22 |
2018-06-28 |
The Charles Stark Draper Laboratory, Inc. |
System and method of using a microfluidic electroporation device for cell treatment
|
US20180203017A1
(en)
|
2016-12-30 |
2018-07-19 |
The Board Of Trustees Of The Leland Stanford Junior University |
Protein-protein interaction detection systems and methods of use thereof
|
SG11201906699WA
(en)
*
|
2017-01-20 |
2019-08-27 |
Lifefoundry Inc |
Systems and methods for supporting multiple automated workflows
|
EP4317447A3
(en)
|
2017-02-15 |
2024-05-01 |
2seventy bio, Inc. |
Donor repair templates multiplex genome editing
|
AU2018240515A1
(en)
|
2017-03-24 |
2019-08-01 |
CureVac SE |
Nucleic acids encoding CRISPR-associated proteins and uses thereof
|
US20180362590A1
(en)
|
2017-04-14 |
2018-12-20 |
Synthetic Genomics, Inc. |
Polypeptides with type v crispr activity and uses thereof
|
US10011849B1
(en)
|
2017-06-23 |
2018-07-03 |
Inscripta, Inc. |
Nucleic acid-guided nucleases
|
US9982279B1
(en)
|
2017-06-23 |
2018-05-29 |
Inscripta, Inc. |
Nucleic acid-guided nucleases
|
EP3848459A1
(en)
|
2017-06-30 |
2021-07-14 |
Inscripta, Inc. |
Automated cell processing methods, modules, instruments and systems
|
AU2018324180A1
(en)
|
2017-09-01 |
2020-03-19 |
Lonza Cologne Gmbh |
End-to-end cell therapy automation
|
AU2018334273A1
(en)
|
2017-09-15 |
2020-04-30 |
Brandeis University |
Multiplex production and barcoding of genetically engineered cells
|
WO2019075200A1
(en)
|
2017-10-12 |
2019-04-18 |
The Jackson Laboratory |
METHODS AND COMPOSITIONS OF TRANSGENIC SELECTION
|
US20190225928A1
(en)
|
2018-01-22 |
2019-07-25 |
Inscripta, Inc. |
Automated cell processing methods, modules, instruments, and systems comprising filtration devices
|
WO2019200004A1
(en)
|
2018-04-13 |
2019-10-17 |
Inscripta, Inc. |
Automated cell processing instruments comprising reagent cartridges
|
US10501738B2
(en)
|
2018-04-24 |
2019-12-10 |
Inscripta, Inc. |
Automated instrumentation for production of peptide libraries
|
US10227576B1
(en)
|
2018-06-13 |
2019-03-12 |
Caribou Biosciences, Inc. |
Engineered cascade components and cascade complexes
|
AU2019292919A1
(en)
|
2018-06-30 |
2021-03-11 |
Inscripta, Inc. |
Instruments, modules, and methods for improved detection of edited sequences in live cells
|
AU2019311290A1
(en)
|
2018-07-26 |
2021-01-28 |
Ospedale Pediatrico Bambino Gesù (Opbg) |
Therapeutic preparations of gamma-delta T cells and Natural Killer cells and methods for manufacture and use
|
CA3109953A1
(en)
|
2018-08-28 |
2020-03-05 |
Flagship Pioneering Innovations Vi, Llc |
Methods and compositions for modulating a genome
|
US11965154B2
(en)
|
2018-08-30 |
2024-04-23 |
Inscripta, Inc. |
Detection of nuclease edited sequences in automated modules and instruments
|
GB201816522D0
(en)
|
2018-10-10 |
2018-11-28 |
Autolus Ltd |
Methods and reagents for analysing nucleic acids from single cells
|
WO2020191102A1
(en)
|
2019-03-18 |
2020-09-24 |
The Broad Institute, Inc. |
Type vii crispr proteins and systems
|
JP2022526908A
(ja)
|
2019-03-19 |
2022-05-27 |
ザ ブロード インスティテュート,インコーポレーテッド |
編集ヌクレオチド配列を編集するための方法および組成物
|
GB201905651D0
(en)
|
2019-04-24 |
2019-06-05 |
Lightbio Ltd |
Nucleic acid constructs and methods for their manufacture
|
EP3953477A4
(en)
|
2019-06-06 |
2022-06-22 |
Inscripta, Inc. |
HARDENING FOR RECURSIVE NUCLEIC ACID-DRIVEN CELL EDITING
|
US10927385B2
(en)
|
2019-06-25 |
2021-02-23 |
Inscripta, Inc. |
Increased nucleic-acid guided cell editing in yeast
|
US10704033B1
(en)
|
2019-12-13 |
2020-07-07 |
Inscripta, Inc. |
Nucleic acid-guided nucleases
|
US20210317444A1
(en)
|
2020-04-08 |
2021-10-14 |
Inscripta, Inc. |
System and method for gene editing cassette design
|