PT2748182T - Nanopartículas peptídicas e utilizações das mesmas - Google Patents

Nanopartículas peptídicas e utilizações das mesmas Download PDF

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Publication number
PT2748182T
PT2748182T PT127565935T PT12756593T PT2748182T PT 2748182 T PT2748182 T PT 2748182T PT 127565935 T PT127565935 T PT 127565935T PT 12756593 T PT12756593 T PT 12756593T PT 2748182 T PT2748182 T PT 2748182T
Authority
PT
Portugal
Prior art keywords
trp
leu
peptide
particle
peptidic
Prior art date
Application number
PT127565935T
Other languages
English (en)
Portuguese (pt)
Inventor
Dittrich Christian
Danuser Gaudenz
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College filed Critical Harvard College
Publication of PT2748182T publication Critical patent/PT2748182T/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/7105Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/711Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/713Double-stranded nucleic acids or oligonucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • A61K9/4825Proteins, e.g. gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5169Proteins, e.g. albumin, gelatin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT127565935T 2011-08-23 2012-08-23 Nanopartículas peptídicas e utilizações das mesmas PT2748182T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161526526P 2011-08-23 2011-08-23

Publications (1)

Publication Number Publication Date
PT2748182T true PT2748182T (pt) 2017-01-20

Family

ID=46826904

Family Applications (1)

Application Number Title Priority Date Filing Date
PT127565935T PT2748182T (pt) 2011-08-23 2012-08-23 Nanopartículas peptídicas e utilizações das mesmas

Country Status (19)

Country Link
US (1) US8828928B2 (enExample)
EP (1) EP2748182B1 (enExample)
JP (1) JP2014524477A (enExample)
KR (1) KR20140068087A (enExample)
CN (1) CN104011065B (enExample)
AU (1) AU2012298824B2 (enExample)
BR (1) BR112014004014A2 (enExample)
CA (1) CA2845886A1 (enExample)
CL (1) CL2014000418A1 (enExample)
DK (1) DK2748182T3 (enExample)
ES (1) ES2610779T3 (enExample)
HU (1) HUE031511T2 (enExample)
IL (1) IL231005A0 (enExample)
MX (1) MX2014002062A (enExample)
PT (1) PT2748182T (enExample)
RU (1) RU2014110901A (enExample)
SG (1) SG11201400073SA (enExample)
WO (1) WO2013028843A1 (enExample)
ZA (1) ZA201401210B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8153435B1 (en) 2005-03-30 2012-04-10 Tracer Detection Technology Corp. Methods and articles for identifying objects using encapsulated perfluorocarbon tracers
US11286489B2 (en) * 2016-02-11 2022-03-29 The Curators Of The University Of Missouri POSH inhibitor complex biomolecules and amphiphile micelles
WO2017165452A1 (en) 2016-03-21 2017-09-28 Rhode Island Council On Postsecondary Education pH-SENSITIVE PEPTIDES
PT3554681T (pt) * 2016-12-16 2022-03-21 Brigham & Womens Hospital Inc Método para matriz de sensores de coroa de proteínas para a deteção precoce de doenças
CN106832003B (zh) * 2017-02-15 2021-01-05 中国药科大学 一种酸敏性多肽及其应用
JP2021521270A (ja) 2018-04-06 2021-08-26 アンマ セラピューティクス インコーポレイテッドAmma Therapeutics, Inc. 治療剤の制御放出用組成物
US12319711B2 (en) 2019-09-20 2025-06-03 Northwestern University Spherical nucleic acids with tailored and active protein coronae
US12378560B2 (en) 2019-10-29 2025-08-05 Northwestern University Sequence multiplicity within spherical nucleic acids
CN114516819B (zh) * 2022-02-25 2024-02-27 顺毅宜昌化工有限公司 一种n,n’-二乙酰基肼的制备方法
WO2023244536A2 (en) * 2022-06-13 2023-12-21 Neubase Therapeutics, Inc. Oligonucleotide analogue formulations
CN116004221B (zh) * 2022-12-15 2023-12-19 湖南卓润生物科技有限公司 环肽的新应用、吖啶标记复合物与制备方法、检测试剂盒

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3270960A (en) 1964-09-11 1966-09-06 Sperry Rand Corp Fluid sensor
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US3872925A (en) 1973-04-24 1975-03-25 Gearhart Owen Industries Through-tubing bridge plug
US3842067A (en) 1973-07-27 1974-10-15 American Home Prod Synthesis of(des-asn5)-srif and intermediates
JPS5726506B2 (enExample) 1974-03-08 1982-06-04
US4105603A (en) 1977-03-28 1978-08-08 The Salk Institute For Biological Studies Peptides which effect release of hormones
US4511390A (en) 1983-06-10 1985-04-16 E. I. Du Pont De Nemours And Company Aralkylcarbamoyl peptide alcohols
US5643873A (en) 1992-05-06 1997-07-01 Affymax Technologies N.V. Peptides and compounds that bind selectins including endothelial leukocyte adhesion molecule 1
US5625048A (en) 1994-11-10 1997-04-29 The Regents Of The University Of California Modified green fluorescent proteins
US5654276A (en) 1995-06-07 1997-08-05 Affymax Technologies N.V. Peptides and compounds that bind to the IL-5 receptor
FR2736642B1 (fr) 1995-07-10 1997-09-12 Pasteur Institut Immunovecteurs, notamment anticorps et fragments d'anticorps utilisables pour le transport intracellulaire et intranucleaire de principes biologiquement actifs notamment d'haptenes, de proteines et d'acides nucleiques
US6124128A (en) 1996-08-16 2000-09-26 The Regents Of The University Of California Long wavelength engineered fluorescent proteins
DE60015564T2 (de) 1999-08-02 2005-12-22 Synt:Em (S.A.) Berechnungsmethoden zur herstellung von molekularen mimetika
CA2439400A1 (en) 2001-02-26 2002-09-06 The Regents Of The University Of California Non-oligomerizing tandem fluorescent proteins
JP5255274B2 (ja) 2004-07-06 2013-08-07 スリーディー マトリックス, インコーポレイテッド 精製両親媒性ペプチド組成物およびその使用
EP2235043A2 (en) * 2008-02-01 2010-10-06 Alpha-O Peptides AG Self-assembling peptide nanoparticles useful as vaccines
WO2009134808A2 (en) * 2008-04-28 2009-11-05 President And Fellows Of Harvard College Supercharged proteins for cell penetration

Also Published As

Publication number Publication date
SG11201400073SA (en) 2014-03-28
ZA201401210B (en) 2015-12-23
BR112014004014A2 (pt) 2020-10-27
EP2748182A1 (en) 2014-07-02
ES2610779T3 (es) 2017-05-03
WO2013028843A1 (en) 2013-02-28
IL231005A0 (en) 2014-03-31
JP2014524477A (ja) 2014-09-22
NZ622045A (en) 2016-02-26
CL2014000418A1 (es) 2014-07-25
EP2748182B1 (en) 2016-10-19
HUE031511T2 (en) 2017-07-28
CA2845886A1 (en) 2013-02-28
CN104011065A (zh) 2014-08-27
CN104011065B (zh) 2017-06-30
AU2012298824B2 (en) 2017-06-01
RU2014110901A (ru) 2015-09-27
US8828928B2 (en) 2014-09-09
KR20140068087A (ko) 2014-06-05
MX2014002062A (es) 2014-05-28
US20130064895A1 (en) 2013-03-14
DK2748182T3 (en) 2017-02-06
AU2012298824A1 (en) 2014-03-20

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