CL2014000418A1 - Particula de peptido que comprende un ligando en su superficie externa y uno o dos peptidos anfifilicos, los cuales comprenden un segmento peptidilo hidrofobico y un segmento peptidilo hidrofilico; y su uso para el suministro de un agente activo a una celula. - Google Patents
Particula de peptido que comprende un ligando en su superficie externa y uno o dos peptidos anfifilicos, los cuales comprenden un segmento peptidilo hidrofobico y un segmento peptidilo hidrofilico; y su uso para el suministro de un agente activo a una celula.Info
- Publication number
- CL2014000418A1 CL2014000418A1 CL2014000418A CL2014000418A CL2014000418A1 CL 2014000418 A1 CL2014000418 A1 CL 2014000418A1 CL 2014000418 A CL2014000418 A CL 2014000418A CL 2014000418 A CL2014000418 A CL 2014000418A CL 2014000418 A1 CL2014000418 A1 CL 2014000418A1
- Authority
- CL
- Chile
- Prior art keywords
- peptidyl segment
- ligand
- cell
- supply
- active agent
- Prior art date
Links
- 125000001151 peptidyl group Chemical group 0.000 title 2
- 108090000765 processed proteins & peptides Proteins 0.000 title 2
- 239000013543 active substance Substances 0.000 title 1
- 230000002209 hydrophobic effect Effects 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
- 239000002245 particle Substances 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161526526P | 2011-08-23 | 2011-08-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2014000418A1 true CL2014000418A1 (es) | 2014-07-25 |
Family
ID=46826904
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2014000418A CL2014000418A1 (es) | 2011-08-23 | 2014-02-20 | Particula de peptido que comprende un ligando en su superficie externa y uno o dos peptidos anfifilicos, los cuales comprenden un segmento peptidilo hidrofobico y un segmento peptidilo hidrofilico; y su uso para el suministro de un agente activo a una celula. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US8828928B2 (enExample) |
| EP (1) | EP2748182B1 (enExample) |
| JP (1) | JP2014524477A (enExample) |
| KR (1) | KR20140068087A (enExample) |
| CN (1) | CN104011065B (enExample) |
| AU (1) | AU2012298824B2 (enExample) |
| BR (1) | BR112014004014A2 (enExample) |
| CA (1) | CA2845886A1 (enExample) |
| CL (1) | CL2014000418A1 (enExample) |
| DK (1) | DK2748182T3 (enExample) |
| ES (1) | ES2610779T3 (enExample) |
| HU (1) | HUE031511T2 (enExample) |
| IL (1) | IL231005A0 (enExample) |
| MX (1) | MX2014002062A (enExample) |
| PT (1) | PT2748182T (enExample) |
| RU (1) | RU2014110901A (enExample) |
| SG (1) | SG11201400073SA (enExample) |
| WO (1) | WO2013028843A1 (enExample) |
| ZA (1) | ZA201401210B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8153435B1 (en) | 2005-03-30 | 2012-04-10 | Tracer Detection Technology Corp. | Methods and articles for identifying objects using encapsulated perfluorocarbon tracers |
| US11286489B2 (en) * | 2016-02-11 | 2022-03-29 | The Curators Of The University Of Missouri | POSH inhibitor complex biomolecules and amphiphile micelles |
| WO2017165452A1 (en) | 2016-03-21 | 2017-09-28 | Rhode Island Council On Postsecondary Education | pH-SENSITIVE PEPTIDES |
| PT3554681T (pt) * | 2016-12-16 | 2022-03-21 | Brigham & Womens Hospital Inc | Método para matriz de sensores de coroa de proteínas para a deteção precoce de doenças |
| CN106832003B (zh) * | 2017-02-15 | 2021-01-05 | 中国药科大学 | 一种酸敏性多肽及其应用 |
| JP2021521270A (ja) | 2018-04-06 | 2021-08-26 | アンマ セラピューティクス インコーポレイテッドＡｍｍａ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． | 治療剤の制御放出用組成物 |
| US12319711B2 (en) | 2019-09-20 | 2025-06-03 | Northwestern University | Spherical nucleic acids with tailored and active protein coronae |
| US12378560B2 (en) | 2019-10-29 | 2025-08-05 | Northwestern University | Sequence multiplicity within spherical nucleic acids |
| CN114516819B (zh) * | 2022-02-25 | 2024-02-27 | 顺毅宜昌化工有限公司 | 一种n,n’-二乙酰基肼的制备方法 |
| WO2023244536A2 (en) * | 2022-06-13 | 2023-12-21 | Neubase Therapeutics, Inc. | Oligonucleotide analogue formulations |
| CN116004221B (zh) * | 2022-12-15 | 2023-12-19 | 湖南卓润生物科技有限公司 | 环肽的新应用、吖啶标记复合物与制备方法、检测试剂盒 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3270960A (en) | 1964-09-11 | 1966-09-06 | Sperry Rand Corp | Fluid sensor |
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US3872925A (en) | 1973-04-24 | 1975-03-25 | Gearhart Owen Industries | Through-tubing bridge plug |
| US3842067A (en) | 1973-07-27 | 1974-10-15 | American Home Prod | Synthesis of(des-asn5)-srif and intermediates |
| JPS5726506B2 (enExample) | 1974-03-08 | 1982-06-04 | ||
| US4105603A (en) | 1977-03-28 | 1978-08-08 | The Salk Institute For Biological Studies | Peptides which effect release of hormones |
| US4511390A (en) | 1983-06-10 | 1985-04-16 | E. I. Du Pont De Nemours And Company | Aralkylcarbamoyl peptide alcohols |
| US5643873A (en) | 1992-05-06 | 1997-07-01 | Affymax Technologies N.V. | Peptides and compounds that bind selectins including endothelial leukocyte adhesion molecule 1 |
| US5625048A (en) | 1994-11-10 | 1997-04-29 | The Regents Of The University Of California | Modified green fluorescent proteins |
| US5654276A (en) | 1995-06-07 | 1997-08-05 | Affymax Technologies N.V. | Peptides and compounds that bind to the IL-5 receptor |
| FR2736642B1 (fr) | 1995-07-10 | 1997-09-12 | Pasteur Institut | Immunovecteurs, notamment anticorps et fragments d'anticorps utilisables pour le transport intracellulaire et intranucleaire de principes biologiquement actifs notamment d'haptenes, de proteines et d'acides nucleiques |
| US6124128A (en) | 1996-08-16 | 2000-09-26 | The Regents Of The University Of California | Long wavelength engineered fluorescent proteins |
| DE60015564T2 (de) | 1999-08-02 | 2005-12-22 | Synt:Em (S.A.) | Berechnungsmethoden zur herstellung von molekularen mimetika |
| CA2439400A1 (en) | 2001-02-26 | 2002-09-06 | The Regents Of The University Of California | Non-oligomerizing tandem fluorescent proteins |
| JP5255274B2 (ja) | 2004-07-06 | 2013-08-07 | スリーディー マトリックス， インコーポレイテッド | 精製両親媒性ペプチド組成物およびその使用 |
| EP2235043A2 (en) * | 2008-02-01 | 2010-10-06 | Alpha-O Peptides AG | Self-assembling peptide nanoparticles useful as vaccines |
| WO2009134808A2 (en) * | 2008-04-28 | 2009-11-05 | President And Fellows Of Harvard College | Supercharged proteins for cell penetration |
-
2012
- 2012-08-23 US US13/592,733 patent/US8828928B2/en not_active Expired - Fee Related
- 2012-08-23 RU RU2014110901/10A patent/RU2014110901A/ru not_active Application Discontinuation
- 2012-08-23 MX MX2014002062A patent/MX2014002062A/es unknown
- 2012-08-23 KR KR1020147007599A patent/KR20140068087A/ko not_active Withdrawn
- 2012-08-23 HU HUE12756593A patent/HUE031511T2/en unknown
- 2012-08-23 PT PT127565935T patent/PT2748182T/pt unknown
- 2012-08-23 EP EP12756593.5A patent/EP2748182B1/en not_active Not-in-force
- 2012-08-23 ES ES12756593.5T patent/ES2610779T3/es active Active
- 2012-08-23 AU AU2012298824A patent/AU2012298824B2/en not_active Expired - Fee Related
- 2012-08-23 BR BR112014004014-1A patent/BR112014004014A2/pt not_active IP Right Cessation
- 2012-08-23 JP JP2014527288A patent/JP2014524477A/ja not_active Ceased
- 2012-08-23 CN CN201280052123.9A patent/CN104011065B/zh not_active Expired - Fee Related
- 2012-08-23 DK DK12756593.5T patent/DK2748182T3/en active
- 2012-08-23 WO PCT/US2012/052027 patent/WO2013028843A1/en not_active Ceased
- 2012-08-23 CA CA2845886A patent/CA2845886A1/en not_active Abandoned
- 2012-08-23 SG SG11201400073SA patent/SG11201400073SA/en unknown
-
2014
- 2014-02-17 IL IL231005A patent/IL231005A0/en unknown
- 2014-02-18 ZA ZA2014/01210A patent/ZA201401210B/en unknown
- 2014-02-20 CL CL2014000418A patent/CL2014000418A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SG11201400073SA (en) | 2014-03-28 |
| PT2748182T (pt) | 2017-01-20 |
| ZA201401210B (en) | 2015-12-23 |
| BR112014004014A2 (pt) | 2020-10-27 |
| EP2748182A1 (en) | 2014-07-02 |
| ES2610779T3 (es) | 2017-05-03 |
| WO2013028843A1 (en) | 2013-02-28 |
| IL231005A0 (en) | 2014-03-31 |
| JP2014524477A (ja) | 2014-09-22 |
| NZ622045A (en) | 2016-02-26 |
| EP2748182B1 (en) | 2016-10-19 |
| HUE031511T2 (en) | 2017-07-28 |
| CA2845886A1 (en) | 2013-02-28 |
| CN104011065A (zh) | 2014-08-27 |
| CN104011065B (zh) | 2017-06-30 |
| AU2012298824B2 (en) | 2017-06-01 |
| RU2014110901A (ru) | 2015-09-27 |
| US8828928B2 (en) | 2014-09-09 |
| KR20140068087A (ko) | 2014-06-05 |
| MX2014002062A (es) | 2014-05-28 |
| US20130064895A1 (en) | 2013-03-14 |
| DK2748182T3 (en) | 2017-02-06 |
| AU2012298824A1 (en) | 2014-03-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CL2014000418A1 (es) | Particula de peptido que comprende un ligando en su superficie externa y uno o dos peptidos anfifilicos, los cuales comprenden un segmento peptidilo hidrofobico y un segmento peptidilo hidrofilico; y su uso para el suministro de un agente activo a una celula. | |
| IL282198A (en) | Compositions of functional mitochondria and uses thereof | |
| IL249830A0 (en) | Parasiticidal compositions comprising an isoxazoline active agent, methods and uses thereof | |
| CL2015000345A1 (es) | Uso de una combinación para el melanoma que comprende la administración de cobimetinib y vemurafenib. | |
| ZA201506916B (en) | Microstructure array for delivery of active agents | |
| BR112015022625A2 (pt) | micromatrizes para entrega de agente terapêutico e métodos de uso | |
| PL3160565T3 (pl) | Urządzenia i systemy do dopłucnego dostarczania środków aktywnych | |
| PL3160554T3 (pl) | Urządzenia i systemy do dopłucnego dostarczania środków aktywnych | |
| SMT201600398B (it) | Inibitori di proteina chinasi (varianti), uso di questi nel trattamento di malattie oncologiche e composizione farmaceutica basata su questi | |
| EP3000144A4 (en) | Surface treated silicon containing active materials for electrochemical cells | |
| LT3310904T (lt) | Ląstelinė kryptinga sistema aktyvių ingredientų tiekimui | |
| BRPI0810899A2 (pt) | Formulação de nanopartículas de plga ativadas carregadas com agente ativo para substâncias nano-terapêuticas anticâncer direcionais. | |
| CL2012003281A1 (es) | Uso de compuestos específicos estimuladores y/o activadores de sgc; formulacion farmaceutica que comprende dichos compuestos; kit que comprende los compuestos, y uso para la prevencion y/o tratamiento de la esclerosis sistematica. | |
| PL3333164T3 (pl) | Modulatory transportu jądrowego zawierające ugrupowanie hydrazydu i ich zastosowania | |
| UY35847A (es) | Un método para controlar la roya | |
| EP2922877A4 (en) | IMPROVED PEPTIDATE MEDICINES | |
| CR20140487A (es) | Peliculas de capas multiples capaces de liberar ingredientes activos por un periodo limitado de tiempo | |
| HRP20181364T8 (hr) | Aminotriazolopiridin, namijenjen upotrebi u liječenju upale, te njegovi farmacetski pripravci | |
| CL2015001279A1 (es) | Compuestos derivados de piridina, inhibidores del transportador de uratos urat 1; composicion farmaceutica que los comprende; uso para el tratamiento o prevencion de enfermedades tales como gota, hiperuricemia, hipertensión, enfermedades renales, entre otras. | |
| ECSP17044282A (es) | Formulación de relación fija de insulina glargina/lixisenatida | |
| BR112013014616A2 (pt) | sistema terapêutico transdérmico para a administração de uma substância ativa | |
| LT3324948T (lt) | Daugiasluoksnės farmaciniu požiūriu aktyvaus junginio atpalaidavimo mikrodalelės skystoje vaisto formoje | |
| CL2014001861A1 (es) | Compuestos derivados de bencil sulfonamida, inhibidores de mogat-2; compuesto cristalino; composicion farmaceutica; y su uso en el tratamiento de la hipertrigliceridemia. | |
| CR20130689A (es) | Cepa ts-15 de paenibacillus alvei y su uso en el control de organismos patógenos | |
| FR3003396B1 (fr) | Structures semi-conductrices dotees de regions actives comprenant de l'ingan |