PT2032592E - Processos para o empacotamento de oligonucleótidos em partículas semelhantes a vírus de bacteriófagos de arn - Google Patents

Processos para o empacotamento de oligonucleótidos em partículas semelhantes a vírus de bacteriófagos de arn Download PDF

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Publication number
PT2032592E
PT2032592E PT77646271T PT07764627T PT2032592E PT 2032592 E PT2032592 E PT 2032592E PT 77646271 T PT77646271 T PT 77646271T PT 07764627 T PT07764627 T PT 07764627T PT 2032592 E PT2032592 E PT 2032592E
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Prior art keywords
oligonucleotide
quot
seq
temperature
solution
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PT77646271T
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English (en)
Portuguese (pt)
Inventor
Matthias Kinzler
Karl Proba
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Cytos Biotechnology Ag
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Priority claimed from PCT/EP2006/069734 external-priority patent/WO2007068747A1/en
Application filed by Cytos Biotechnology Ag filed Critical Cytos Biotechnology Ag
Publication of PT2032592E publication Critical patent/PT2032592E/pt

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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N15/86Viral vectors
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    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/117Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
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    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • C12N2310/00Structure or type of the nucleic acid
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    • C12N2310/17Immunomodulatory nucleic acids
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    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/00034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/18011Details ssRNA Bacteriophages positive-sense
    • C12N2795/18111Leviviridae
    • C12N2795/18122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/18011Details ssRNA Bacteriophages positive-sense
    • C12N2795/18111Leviviridae
    • C12N2795/18123Virus like particles [VLP]

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  • Crystallography & Structural Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PT77646271T 2006-06-12 2007-06-12 Processos para o empacotamento de oligonucleótidos em partículas semelhantes a vírus de bacteriófagos de arn PT2032592E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81259206P 2006-06-12 2006-06-12
PCT/EP2006/069734 WO2007068747A1 (en) 2005-12-14 2006-12-14 Immunostimulatory nucleic acid packaged particles for the treatment of hypersensitivity

Publications (1)

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PT2032592E true PT2032592E (pt) 2013-08-28

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PT77646271T PT2032592E (pt) 2006-06-12 2007-06-12 Processos para o empacotamento de oligonucleótidos em partículas semelhantes a vírus de bacteriófagos de arn

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US (4) US8541559B2 (enExample)
EP (2) EP2032592B1 (enExample)
JP (2) JP5437797B2 (enExample)
KR (1) KR101552227B1 (enExample)
CN (1) CN101466720B (enExample)
AU (1) AU2007260236B2 (enExample)
BR (1) BRPI0713651B1 (enExample)
CA (1) CA2655108C (enExample)
DK (1) DK2032592T3 (enExample)
ES (2) ES2738986T3 (enExample)
IL (1) IL195526A (enExample)
MX (1) MX2008015529A (enExample)
NZ (1) NZ573622A (enExample)
PL (1) PL2032592T3 (enExample)
PT (1) PT2032592E (enExample)
RU (1) RU2476595C2 (enExample)
SG (1) SG172696A1 (enExample)
SI (1) SI2032592T1 (enExample)
WO (1) WO2007144150A1 (enExample)
ZA (1) ZA200810109B (enExample)

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