PT1423168E - Composicao farmaceutica que compreende gabapentina ou um seu analogo e uma x-aminoamida e a sua utilizacao como analgesico - Google Patents

Composicao farmaceutica que compreende gabapentina ou um seu analogo e uma x-aminoamida e a sua utilizacao como analgesico

Info

Publication number
PT1423168E
PT1423168E PT02797573T PT02797573T PT1423168E PT 1423168 E PT1423168 E PT 1423168E PT 02797573 T PT02797573 T PT 02797573T PT 02797573 T PT02797573 T PT 02797573T PT 1423168 E PT1423168 E PT 1423168E
Authority
PT
Portugal
Prior art keywords
analgesic
aminoamide
analogue
pharmaceutical composition
gabapentine
Prior art date
Application number
PT02797573T
Other languages
English (en)
Portuguese (pt)
Inventor
Salvati Patricia
Veneroni Orietta
Maj Roberto
Ruggero Fariello
Benatti Luca
Original Assignee
Newron Pharm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newron Pharm Spa filed Critical Newron Pharm Spa
Publication of PT1423168E publication Critical patent/PT1423168E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT02797573T 2001-09-03 2002-08-09 Composicao farmaceutica que compreende gabapentina ou um seu analogo e uma x-aminoamida e a sua utilizacao como analgesico PT1423168E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01121069 2001-09-03

Publications (1)

Publication Number Publication Date
PT1423168E true PT1423168E (pt) 2006-05-31

Family

ID=8178510

Family Applications (1)

Application Number Title Priority Date Filing Date
PT02797573T PT1423168E (pt) 2001-09-03 2002-08-09 Composicao farmaceutica que compreende gabapentina ou um seu analogo e uma x-aminoamida e a sua utilizacao como analgesico

Country Status (20)

Country Link
US (2) US8084447B2 (enExample)
EP (1) EP1423168B1 (enExample)
JP (1) JP4350508B2 (enExample)
KR (1) KR100890875B1 (enExample)
CN (1) CN1274306C (enExample)
AT (1) ATE317280T1 (enExample)
AU (1) AU2002333374B2 (enExample)
BR (1) BRPI0212298B8 (enExample)
CA (1) CA2459470C (enExample)
DE (1) DE60209152T2 (enExample)
DK (1) DK1423168T3 (enExample)
ES (1) ES2253579T3 (enExample)
IL (2) IL160523A0 (enExample)
MX (1) MXPA04002009A (enExample)
NO (1) NO331298B1 (enExample)
NZ (1) NZ531586A (enExample)
PT (1) PT1423168E (enExample)
RU (1) RU2295337C2 (enExample)
SI (1) SI1423168T1 (enExample)
WO (1) WO2003020273A2 (enExample)

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CN1274306C (zh) 2001-09-03 2006-09-13 纽朗制药有限公司 包含加巴喷丁或其类似物和α－氨基酰胺的药物组合物及其止痛应用
EP1438956A1 (en) * 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
AU2004207010A1 (en) * 2003-01-30 2004-08-12 Dynogen Pharmaceuticals, Inc. Methods of treating lower urinary tract disorders using sodium channel modulators
US20040248979A1 (en) * 2003-06-03 2004-12-09 Dynogen Pharmaceuticals, Inc. Method of treating lower urinary tract disorders
US20070276046A1 (en) * 2003-08-25 2007-11-29 Patricia Salvati Alpha-Aminoamide Derivatives Useful as Anti-Inflammatory Agents
EP1533302A1 (en) * 2003-11-21 2005-05-25 Newron Pharmaceuticals S.p.A. Histidine derivatives
EP1557166A1 (en) 2004-01-21 2005-07-27 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of lower urinary tract disorders
RS51411B (sr) * 2004-09-10 2011-02-28 Newron Pharmaceuticals S.P.A. Upotreba (r)-(halobenziloksi) benzilamino-propanamida kao selektivnih modulatora natrijumovih i/ili kalcijumovih kanala
ES2372700T3 (es) * 2005-05-10 2012-01-25 Teva Pharmaceutical Industries Ltd Resolución óptica del ácido 3-carbamoilmetil-5-metil hexanoico.
CN100410242C (zh) * 2005-06-23 2008-08-13 江苏恩华药业股份有限公司 普瑞巴林中间体及其制备方法
WO2007035789A1 (en) 2005-09-19 2007-03-29 Teva Pharmaceutical Industries Ltd. Chiral 3-carbamoylmethyl-5-methyl hexanoic acids, key intermediates for the new synthesis of (s)-pregabalin
EP1798236A1 (en) * 2005-12-13 2007-06-20 EOS Eczacibasi Ozgun Kimyasal Urunler Sanayi Ve Ti Caret A.S. Process for the preparation of 3-pyridyl-1-hydroxyethylidene-1,1- biphosphonic acid and hydrated forms thereof
IN266803B (enExample) 2005-12-22 2015-06-03 Newron Pharm Spa
KR101491541B1 (ko) 2006-06-19 2015-02-09 뉴론 파마슈티칼즈 에스. 피. 에이. 2-［4-(3- 및 2-플루오로벤질옥시)벤질아미노)프로판 아미드의 제조방법
TR201802576T4 (tr) 2007-06-15 2018-03-21 Newron Pharm Spa Sübsti̇tüe edi̇lmi̇ş 2-[2-(feni̇l)eti̇lami̇no]alkanami̇t türevleri̇ ve bunlarin sodyum ve/veya kalsi̇yum kanal modülatörleri̇ olarak kullanimi
EP3257842B1 (en) 2007-12-11 2020-11-18 Newron Pharmaceuticals S.p.A. Therapeutic use of 2-[4-(3- or 2-fluorobenzyloxy)benzylamino]propanamides with high purity degree
US9192681B2 (en) 2009-02-24 2015-11-24 Nektar Therapeutics Oligomer-amino acid conjugates
LT2563355T (lt) 2010-04-27 2016-09-26 Newron Pharmaceuticals S.P.A. Ralfinamido metansulfonato druskų arba jų r-enentiomerų gavimo būdas
CN112955145A (zh) * 2018-09-04 2021-06-11 密涅瓦神经科学有限公司 使用苯氧丙胺化合物治疗疼痛的方法
IT201900006602A1 (it) * 2019-05-07 2020-11-07 Acraf Composizione farmaceutica per il trattamento del dolore neuropatico
CN120025292B (zh) * 2025-01-06 2026-04-28 江苏海洋大学 一种具有协同镇痛作用的化合物及其药物组合物、制备方法和用途

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Also Published As

Publication number Publication date
US20120142777A1 (en) 2012-06-07
JP4350508B2 (ja) 2009-10-21
BR0212298A (pt) 2004-09-14
WO2003020273A3 (en) 2003-09-04
RU2295337C2 (ru) 2007-03-20
EP1423168B1 (en) 2006-02-08
EP1423168A2 (en) 2004-06-02
IL160523A0 (en) 2004-07-25
US8710040B2 (en) 2014-04-29
BRPI0212298B8 (pt) 2021-05-25
NO20040907L (no) 2004-05-14
NO331298B1 (no) 2011-11-21
NZ531586A (en) 2005-09-30
AU2002333374B2 (en) 2007-03-22
MXPA04002009A (es) 2004-07-08
WO2003020273A2 (en) 2003-03-13
ATE317280T1 (de) 2006-02-15
CN1556720A (zh) 2004-12-22
CN1274306C (zh) 2006-09-13
DE60209152T2 (de) 2006-08-03
US8084447B2 (en) 2011-12-27
CA2459470A1 (en) 2003-03-13
RU2004110041A (ru) 2005-03-10
KR100890875B1 (ko) 2009-03-31
CA2459470C (en) 2010-10-12
BRPI0212298B1 (pt) 2015-11-03
HK1070305A1 (en) 2005-06-17
IL160523A (en) 2009-02-11
ES2253579T3 (es) 2006-06-01
JP2005504782A (ja) 2005-02-17
DK1423168T3 (da) 2006-05-15
AU2002333374A2 (en) 2003-03-18
SI1423168T1 (sl) 2006-06-30
US20040248978A1 (en) 2004-12-09
DE60209152D1 (de) 2006-04-20
KR20040034686A (ko) 2004-04-28

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