PL92053B1 - - Google Patents

Download PDF

Info

Publication number
PL92053B1
PL92053B1 PL1974175142A PL17514274A PL92053B1 PL 92053 B1 PL92053 B1 PL 92053B1 PL 1974175142 A PL1974175142 A PL 1974175142A PL 17514274 A PL17514274 A PL 17514274A PL 92053 B1 PL92053 B1 PL 92053B1
Authority
PL
Poland
Prior art keywords
formula
acid
compounds
prepared
hydrochloride
Prior art date
Application number
PL1974175142A
Other languages
English (en)
Polish (pl)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of PL92053B1 publication Critical patent/PL92053B1/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PL1974175142A 1973-10-27 1974-10-26 PL92053B1 (en16)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732354002 DE2354002A1 (de) 1973-10-27 1973-10-27 Neue n-(methoxymethyl-furylmethyl)6,7-benzomorphane und -morphinane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
PL92053B1 true PL92053B1 (en16) 1977-03-31

Family

ID=5896658

Family Applications (3)

Application Number Title Priority Date Filing Date
PL1974175142A PL92053B1 (en16) 1973-10-27 1974-10-26
PL1974175143A PL92052B1 (en16) 1973-10-27 1974-10-26
PL1974175144A PL92086B1 (en16) 1973-10-27 1974-10-26

Family Applications After (2)

Application Number Title Priority Date Filing Date
PL1974175143A PL92052B1 (en16) 1973-10-27 1974-10-26
PL1974175144A PL92086B1 (en16) 1973-10-27 1974-10-26

Country Status (27)

Country Link
US (1) US3981874A (en16)
JP (1) JPS5738590B2 (en16)
AT (6) AT335634B (en16)
BE (1) BE821505A (en16)
BG (3) BG27901A3 (en16)
CA (1) CA1056377A (en16)
CH (6) CH609340A5 (en16)
CS (3) CS171196B2 (en16)
DD (1) DD115909A5 (en16)
DE (1) DE2354002A1 (en16)
DK (1) DK138325C (en16)
ES (6) ES431056A1 (en16)
FI (1) FI62079C (en16)
FR (1) FR2248838B1 (en16)
GB (1) GB1482552A (en16)
HU (1) HU176479B (en16)
IE (1) IE41528B1 (en16)
IL (1) IL45938A (en16)
NL (1) NL7413980A (en16)
NO (1) NO140859C (en16)
PH (1) PH11894A (en16)
PL (3) PL92053B1 (en16)
RO (5) RO65656A (en16)
SE (1) SE422791B (en16)
SU (6) SU510999A3 (en16)
YU (5) YU36950B (en16)
ZA (1) ZA746790B (en16)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1513961A (en) * 1975-02-25 1978-06-14 Acf Chemiefarma Nv 6,7-benzomorphans method for their preparation and intermediates
US4208523A (en) * 1978-11-30 1980-06-17 Sterling Drug Inc. 11-Lower-alkyl-, 11-phenyl-lower-alkyl- and 11-cyclo-lower-alkyl-lower-alkyl-hexahydro-2,6-methano-3-benzazocines
WO2009017664A1 (en) 2007-07-26 2009-02-05 Vitae Pharmaceuticals, Inc. CYCLIC INHIBITORS OF 11β-HYDROXYSTERIOD DEHYDROGENASE 1
JP5769970B2 (ja) * 2007-11-16 2015-08-26 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンゾモルファン及び関連骨格のアリール−及びヘテロアリールカルボニル誘導体、かかる化合物を含有する医薬及びこれらの使用
EP2229368A1 (en) 2007-12-11 2010-09-22 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
WO2009094169A1 (en) 2008-01-24 2009-07-30 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009100872A1 (en) * 2008-02-12 2009-08-20 Boehringer Ingelheim International Gmbh Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
US8598160B2 (en) 2008-02-15 2013-12-03 Vitae Pharmaceuticals, Inc. Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
CA2723039A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
KR20110002492A (ko) 2008-05-01 2011-01-07 비타이 파마슈티컬즈, 인코포레이티드 11베타-하이드록시스테로이드 탈수소효소 1의 고리형 억제제
EP2291370B1 (en) 2008-05-01 2013-11-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW200950780A (en) 2008-05-13 2009-12-16 Boehringer Ingelheim Int Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
US8846668B2 (en) 2008-07-25 2014-09-30 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8114868B2 (en) 2008-07-25 2012-02-14 Boehringer Ingelheim International Gmbh Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
EP2440537A1 (en) 2009-06-11 2012-04-18 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
UY33001A (es) * 2009-11-06 2011-05-31 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina
WO2011159760A1 (en) 2010-06-16 2011-12-22 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
EP2744783A1 (en) 2011-08-17 2014-06-25 Boehringer Ingelheim International GmbH Indenopyridine derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3632591A (en) * 1968-07-19 1972-01-04 Sterling Drug Inc 1 2 3 4 5 6 - hexahydro-3-(cycloaliphatic or cycloaliphatic 11-dimethyl-2 alkyl)-66-methano-3-benzazocines
US3833595A (en) * 1968-12-26 1974-09-03 Sumitomo Chemical Co 2-aroylalkyl benzomorphans
CS166803B2 (en16) * 1971-02-08 1976-03-29 Boehringer Sohn Ingelheim

Also Published As

Publication number Publication date
YU36949B (en) 1984-08-31
CS171196B2 (en16) 1976-10-29
NO140859B (no) 1979-08-20
ES431056A1 (es) 1976-10-16
CH609685A5 (en16) 1979-03-15
AT336202B (de) 1977-04-25
CH609047A5 (en16) 1979-02-15
AT335076B (de) 1977-02-25
RO65657A (ro) 1980-06-15
CH609340A5 (en16) 1979-02-28
SU578870A3 (ru) 1977-10-30
DK559874A (en16) 1975-06-23
SU510999A3 (ru) 1976-04-15
FI62079B (fi) 1982-07-30
RO65658A (fr) 1979-07-15
RO65655A (ro) 1980-06-15
YU285174A (en) 1982-06-18
SE422791B (sv) 1982-03-29
IL45938A0 (en) 1974-12-31
BG27902A3 (bg) 1980-01-15
DK138325B (da) 1978-08-14
PL92086B1 (en16) 1977-03-31
ATA828874A (de) 1976-06-15
PH11894A (en) 1978-08-29
ES431054A1 (es) 1976-10-16
FR2248838B1 (en16) 1977-11-04
PL92052B1 (en16) 1977-03-31
US3981874A (en) 1976-09-21
YU36951B (en) 1984-08-31
ES431058A1 (es) 1976-10-16
IE41528L (en) 1975-04-27
JPS5071679A (en16) 1975-06-13
ES431055A1 (es) 1976-10-16
ES431059A1 (es) 1976-10-16
ATA828974A (de) 1976-08-15
YU285374A (en) 1982-06-18
HU176479B (en) 1981-03-28
AT335634B (de) 1977-03-25
CS171194B2 (en16) 1976-10-29
FI314174A7 (en16) 1975-04-28
ATA828574A (de) 1976-07-15
AT335631B (de) 1977-03-25
SU511005A3 (ru) 1976-04-15
IL45938A (en) 1977-12-30
AT335633B (de) 1977-03-25
YU285474A (en) 1982-06-18
SE7413485L (en16) 1975-04-28
BG27901A3 (bg) 1980-01-15
ATA828674A (de) 1976-07-15
JPS5738590B2 (en16) 1982-08-16
ATA828774A (de) 1976-07-15
YU285274A (en) 1982-02-25
CH609686A5 (en16) 1979-03-15
DD115909A5 (en16) 1975-10-20
SU508192A3 (ru) 1976-03-25
DE2354002A1 (de) 1975-05-07
CA1056377A (en) 1979-06-12
NO140859C (no) 1979-11-28
NL7413980A (nl) 1975-04-29
ATA829074A (de) 1976-07-15
ZA746790B (en) 1976-06-30
RO65659A (ro) 1980-06-15
YU36950B (en) 1984-08-31
RO65656A (ro) 1980-06-15
YU36519B (en) 1984-02-29
FR2248838A1 (en16) 1975-05-23
BG27903A3 (bg) 1980-01-15
GB1482552A (en) 1977-08-10
IE41528B1 (en) 1980-01-30
DK138325C (da) 1979-01-22
FI62079C (fi) 1982-11-10
CS171195B2 (en16) 1976-10-29
BE821505A (fr) 1975-04-25
CH609046A5 (en16) 1979-02-15
YU285674A (en) 1982-06-18
CH609048A5 (en16) 1979-02-15
SU508193A3 (ru) 1976-03-25
NO743845L (en16) 1975-05-26
ES431057A1 (es) 1976-10-16
YU36952B (en) 1984-08-31
AT335632B (de) 1977-03-25
SU512707A3 (ru) 1976-04-30

Similar Documents

Publication Publication Date Title
PL92053B1 (en16)
FI86421C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara 9-amino-1,2,3,4-tetrahydroakridin-1-oler.
EP0006449B1 (de) 2-(2-Alkoxyethyl)-2'-hydroxy-6,7-benzomorphane, deren Säureadditionssalze, diese enthaltende Arzneimittel und Verfahren zu deren Herstellung
PL93699B1 (en16)
PL99816B1 (pl) Sposob wytwarzania nowych 5,9 beta-dwupodstawionych 2-tetrahydrofurfurylo-6,7-benzomorfanow
AU594954B2 (en) Improvements in or relating to organic compounds
US5041451A (en) Tetrahydroisoquinoline and tetrahydrothieno derivatives
US4210648A (en) II-Aminoacyl-5,11-dihydro-6H-pyrido(2,3-B) (1,4)benzodiazepin-6-ones and salts thereof
WO1988007530A1 (en) Psychotropic bicyclic imides
DE69111915T2 (de) Pyrido(2,3-f)(1,4)thiazepine und Pyrido(3,2-b)(1,5)benzothiazepine.
US3534053A (en) Quinuclidine derivatives
JPH0625091B2 (ja) ジヒドロジベンゾシクロヘプチリデン―エチルアミン誘導体その製法ならびに医薬組成物
PL113628B1 (en) Process for preparing novel,substituted in position 11 5,11-dihydro-6h-pyrido/2,3-b//1,4/benzodiazepin-6-ones
HUT54151A (en) Process fopr producing new (r)-(-)-3-quinuclidinone derivatives and pharmaceutical compositions comprising such compounds
DE69619259T2 (de) Amidin- und isothioharnstoffderivate als inhibitoren der stickstoffoxid-synthase
US4087532A (en) Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof
EP0596125A1 (en) Condensed thiophene compound and pharmaceutical use thereof
DE69408484T2 (de) 6,7-Dialkoxy-3,4-dihydroisochinolin-8-ol, Verfahren für seine Herstellung und die Verbindung verwendendes Verfahren für die Herstellung von 6,7-Dialkoxy-1,2,3,4-tetrahydroisochinolin-8-ol
EP0173933A1 (de) 1,6-Naphthyridin-Derivate, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
EP0064685A1 (de) Dibenzo(de,g)chinolin-Derivate, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
US4977176A (en) Pilocarpine compounds which are used as pharmaceutical agents
Coomes et al. Alkaloids of the Papaveraceae. XX. 2, 9-Dimethoxy-3-hydroxypavinane. New alkaloid from Argemone munita subspecies rotundata
US4925848A (en) Derivative of codeine useful as an agonist and process for the preparation of it
US4835174A (en) Pilocarpine derivatives
EP0000716A2 (en) Pyrrolo(2,1-b)(3)benzazepine derivatives, process for their preparation and pharmaceutical compositions containing them