YU36950B - Process for preparing new n-(methoxymethyl-furyl-methyl-6,7-benzomorphanes and - morphinanes - Google Patents
Process for preparing new n-(methoxymethyl-furyl-methyl-6,7-benzomorphanes and - morphinanesInfo
- Publication number
- YU36950B YU36950B YU2856/74A YU285674A YU36950B YU 36950 B YU36950 B YU 36950B YU 2856/74 A YU2856/74 A YU 2856/74A YU 285674 A YU285674 A YU 285674A YU 36950 B YU36950 B YU 36950B
- Authority
- YU
- Yugoslavia
- Prior art keywords
- morphinanes
- benzomorphanes
- methoxymethyl
- furyl
- methyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19732354002 DE2354002A1 (de) | 1973-10-27 | 1973-10-27 | Neue n-(methoxymethyl-furylmethyl)6,7-benzomorphane und -morphinane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| YU285674A YU285674A (en) | 1982-06-18 |
| YU36950B true YU36950B (en) | 1984-08-31 |
Family
ID=5896658
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU2854/74A YU36949B (en) | 1973-10-27 | 1974-10-24 | Process for preparing new n-(methoxymethyl-furyl-methyl)-6,7-benzomorphanes and - morphinanes |
| YU02852/74A YU36519B (en) | 1973-10-27 | 1974-10-24 | Process for preparing new n-(methoxy-methylfurylmethyl)-6,7-benzomorphanes and - morphinanes |
| YU2851/74A YU36951B (en) | 1973-10-27 | 1974-10-24 | Process for preparing new n-(methoxymethyl-furylmethyl)-6,7-benzomorphanes and - morphinanes |
| YU2856/74A YU36950B (en) | 1973-10-27 | 1974-10-24 | Process for preparing new n-(methoxymethyl-furyl-methyl-6,7-benzomorphanes and - morphinanes |
| YU2853/74A YU36952B (en) | 1973-10-27 | 1974-10-24 | Process for preparing new n-(methoxymethyl-furyl-methyl)-6,7-benzomorphanes and-morphinanes |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU2854/74A YU36949B (en) | 1973-10-27 | 1974-10-24 | Process for preparing new n-(methoxymethyl-furyl-methyl)-6,7-benzomorphanes and - morphinanes |
| YU02852/74A YU36519B (en) | 1973-10-27 | 1974-10-24 | Process for preparing new n-(methoxy-methylfurylmethyl)-6,7-benzomorphanes and - morphinanes |
| YU2851/74A YU36951B (en) | 1973-10-27 | 1974-10-24 | Process for preparing new n-(methoxymethyl-furylmethyl)-6,7-benzomorphanes and - morphinanes |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU2853/74A YU36952B (en) | 1973-10-27 | 1974-10-24 | Process for preparing new n-(methoxymethyl-furyl-methyl)-6,7-benzomorphanes and-morphinanes |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US3981874A (en16) |
| JP (1) | JPS5738590B2 (en16) |
| AT (6) | AT335634B (en16) |
| BE (1) | BE821505A (en16) |
| BG (3) | BG27901A3 (en16) |
| CA (1) | CA1056377A (en16) |
| CH (6) | CH609340A5 (en16) |
| CS (3) | CS171195B2 (en16) |
| DD (1) | DD115909A5 (en16) |
| DE (1) | DE2354002A1 (en16) |
| DK (1) | DK138325C (en16) |
| ES (6) | ES431054A1 (en16) |
| FI (1) | FI62079C (en16) |
| FR (1) | FR2248838B1 (en16) |
| GB (1) | GB1482552A (en16) |
| HU (1) | HU176479B (en16) |
| IE (1) | IE41528B1 (en16) |
| IL (1) | IL45938A (en16) |
| NL (1) | NL7413980A (en16) |
| NO (1) | NO140859C (en16) |
| PH (1) | PH11894A (en16) |
| PL (3) | PL92053B1 (en16) |
| RO (5) | RO65656A (en16) |
| SE (1) | SE422791B (en16) |
| SU (6) | SU510999A3 (en16) |
| YU (5) | YU36949B (en16) |
| ZA (1) | ZA746790B (en16) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1513961A (en) * | 1975-02-25 | 1978-06-14 | Acf Chemiefarma Nv | 6,7-benzomorphans method for their preparation and intermediates |
| US4208523A (en) * | 1978-11-30 | 1980-06-17 | Sterling Drug Inc. | 11-Lower-alkyl-, 11-phenyl-lower-alkyl- and 11-cyclo-lower-alkyl-lower-alkyl-hexahydro-2,6-methano-3-benzazocines |
| TW200911796A (en) | 2007-07-26 | 2009-03-16 | Vitae Pharmaceuticals Inc | Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| EP2220048B1 (en) | 2007-11-16 | 2017-01-25 | Boehringer Ingelheim International GmbH | Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use |
| CA2708303A1 (en) | 2007-12-11 | 2009-06-18 | Vitae Pharmaceuticals, Inc. | Cyclic urea inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1 |
| TW200934490A (en) | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
| WO2009094169A1 (en) | 2008-01-24 | 2009-07-30 | Vitae Pharmaceuticals, Inc. | Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| ATE531696T1 (de) * | 2008-02-12 | 2011-11-15 | Boehringer Ingelheim Int | Harnstoff-derivate von benzomorphanen, entsprechende gerüste, medikamente mit solchen verbindungen und ihre verwendung |
| EP2254872A2 (en) | 2008-02-15 | 2010-12-01 | Vitae Pharmaceuticals, Inc. | Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
| CA2723034A1 (en) | 2008-05-01 | 2009-11-05 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| CL2009001059A1 (es) | 2008-05-01 | 2010-11-12 | Boehringer Ingelheim Int | Compuestos derivados de 1,3-oxazin-2-ona-3,6 sustituidos, inhibidores de la actividad de la 11-beta-hidroxiesteroide deshidrogenasa i; composicion farmaceutica que los comprende; utiles en el tratamiento de enfermedades tales como diabetes mellitus, entre otras. |
| US8569292B2 (en) | 2008-05-01 | 2013-10-29 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| JP5711115B2 (ja) | 2008-05-13 | 2015-04-30 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ベンゾモルファン及び関連骨格のアリサイクリックカルボン酸誘導体、そのような化合物を含有する医薬及びその使用 |
| ES2432150T3 (es) | 2008-07-25 | 2013-12-02 | Boehringer Ingelheim International Gmbh | Inhibidores cíclicos de la 11 beta-hidroxiesteroide deshidrogenasa 1 |
| US8846668B2 (en) | 2008-07-25 | 2014-09-30 | Vitae Pharmaceuticals, Inc. | Inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| US8680093B2 (en) | 2009-04-30 | 2014-03-25 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| WO2011011123A1 (en) | 2009-06-11 | 2011-01-27 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure |
| AR078887A1 (es) | 2009-11-06 | 2011-12-07 | Boehringer Ingelheim Int | Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen. |
| WO2011159760A1 (en) | 2010-06-16 | 2011-12-22 | Vitae Pharmaceuticals, Inc. | Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use |
| TWI537258B (zh) | 2010-11-05 | 2016-06-11 | 百靈佳殷格翰國際股份有限公司 | 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物 |
| JP2014524438A (ja) | 2011-08-17 | 2014-09-22 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | インデノピリジン誘導体 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3632591A (en) * | 1968-07-19 | 1972-01-04 | Sterling Drug Inc | 1 2 3 4 5 6 - hexahydro-3-(cycloaliphatic or cycloaliphatic 11-dimethyl-2 alkyl)-66-methano-3-benzazocines |
| US3833595A (en) * | 1968-12-26 | 1974-09-03 | Sumitomo Chemical Co | 2-aroylalkyl benzomorphans |
| CS166803B2 (en16) * | 1971-02-08 | 1976-03-29 | Boehringer Sohn Ingelheim |
-
1973
- 1973-10-25 SU SU2069684A patent/SU510999A3/ru active
- 1973-10-25 SU SU2069691A patent/SU511005A3/ru active
- 1973-10-27 DE DE19732354002 patent/DE2354002A1/de not_active Withdrawn
-
1974
- 1974-01-25 RO RO7480315A patent/RO65656A/ro unknown
- 1974-10-02 CS CS6768A patent/CS171195B2/cs unknown
- 1974-10-02 CS CS6769A patent/CS171196B2/cs unknown
- 1974-10-02 CS CS6767A patent/CS171194B2/cs unknown
- 1974-10-15 US US05/514,474 patent/US3981874A/en not_active Expired - Lifetime
- 1974-10-16 ES ES431054A patent/ES431054A1/es not_active Expired
- 1974-10-16 AT AT829074A patent/AT335634B/de not_active IP Right Cessation
- 1974-10-16 ES ES431059A patent/ES431059A1/es not_active Expired
- 1974-10-16 AT AT828574A patent/AT335631B/de not_active IP Right Cessation
- 1974-10-16 ES ES431057A patent/ES431057A1/es not_active Expired
- 1974-10-16 ES ES431055A patent/ES431055A1/es not_active Expired
- 1974-10-16 AT AT828674A patent/AT335632B/de not_active IP Right Cessation
- 1974-10-16 ES ES431056A patent/ES431056A1/es not_active Expired
- 1974-10-16 AT AT828874A patent/AT335076B/de active
- 1974-10-16 AT AT828974A patent/AT336202B/de not_active IP Right Cessation
- 1974-10-16 AT AT828774A patent/AT335633B/de not_active IP Right Cessation
- 1974-10-16 ES ES431058A patent/ES431058A1/es not_active Expired
- 1974-10-24 PH PH16448A patent/PH11894A/en unknown
- 1974-10-24 CH CH1426574A patent/CH609340A5/xx not_active IP Right Cessation
- 1974-10-24 YU YU2854/74A patent/YU36949B/xx unknown
- 1974-10-24 YU YU02852/74A patent/YU36519B/xx unknown
- 1974-10-24 CH CH1426374A patent/CH609047A5/xx not_active IP Right Cessation
- 1974-10-24 YU YU2851/74A patent/YU36951B/xx unknown
- 1974-10-24 YU YU2856/74A patent/YU36950B/xx unknown
- 1974-10-24 CH CH1426274A patent/CH609046A5/xx not_active IP Right Cessation
- 1974-10-24 YU YU2853/74A patent/YU36952B/xx unknown
- 1974-10-24 CH CH1426474A patent/CH609048A5/xx not_active IP Right Cessation
- 1974-10-25 BG BG028036A patent/BG27901A3/xx unknown
- 1974-10-25 CA CA212,340A patent/CA1056377A/en not_active Expired
- 1974-10-25 DD DD181929A patent/DD115909A5/xx unknown
- 1974-10-25 JP JP12261074A patent/JPS5738590B2/ja not_active Expired
- 1974-10-25 CH CH1436974A patent/CH609685A5/xx not_active IP Right Cessation
- 1974-10-25 FI FI3141/74A patent/FI62079C/fi active
- 1974-10-25 GB GB46323/74A patent/GB1482552A/en not_active Expired
- 1974-10-25 BG BG028037A patent/BG27902A3/xx unknown
- 1974-10-25 BG BG028038A patent/BG27903A3/xx unknown
- 1974-10-25 NO NO743845A patent/NO140859C/no unknown
- 1974-10-25 SU SU2070657A patent/SU508193A3/ru active
- 1974-10-25 SU SU2069689A patent/SU508192A3/ru active
- 1974-10-25 FR FR7435890A patent/FR2248838B1/fr not_active Expired
- 1974-10-25 SU SU7402069685A patent/SU578870A3/ru active
- 1974-10-25 ZA ZA00746790A patent/ZA746790B/xx unknown
- 1974-10-25 RO RO7480318A patent/RO65659A/ro unknown
- 1974-10-25 DK DK559874A patent/DK138325C/da not_active IP Right Cessation
- 1974-10-25 CH CH1437074A patent/CH609686A5/xx not_active IP Right Cessation
- 1974-10-25 BE BE149902A patent/BE821505A/xx not_active IP Right Cessation
- 1974-10-25 RO RO7480317A patent/RO65658A/ro unknown
- 1974-10-25 RO RO7480314A patent/RO65655A/ro unknown
- 1974-10-25 SE SE7413485A patent/SE422791B/xx unknown
- 1974-10-25 SU SU2070713A patent/SU512707A3/ru active
- 1974-10-25 IE IE2206/74A patent/IE41528B1/en unknown
- 1974-10-25 NL NL7413980A patent/NL7413980A/xx unknown
- 1974-10-25 RO RO7480316A patent/RO65657A/ro unknown
- 1974-10-25 HU HU74BO1521A patent/HU176479B/hu unknown
- 1974-10-25 IL IL45938A patent/IL45938A/en unknown
- 1974-10-26 PL PL1974175142A patent/PL92053B1/pl unknown
- 1974-10-26 PL PL1974175144A patent/PL92086B1/pl unknown
- 1974-10-26 PL PL1974175143A patent/PL92052B1/pl unknown
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