PL373960A1 - Nowe przeciwciała ukierunkowane na czynnik tkankowy działające jako antykoagulanty - Google Patents

Nowe przeciwciała ukierunkowane na czynnik tkankowy działające jako antykoagulanty

Info

Publication number
PL373960A1
PL373960A1 PL03373960A PL37396003A PL373960A1 PL 373960 A1 PL373960 A1 PL 373960A1 PL 03373960 A PL03373960 A PL 03373960A PL 37396003 A PL37396003 A PL 37396003A PL 373960 A1 PL373960 A1 PL 373960A1
Authority
PL
Poland
Prior art keywords
anticoagulants
tissue factor
targeted antibodies
novel tissue
factor targeted
Prior art date
Application number
PL03373960A
Other languages
English (en)
Other versions
PL210582B1 (pl
Inventor
David Light
Kirk Mclean
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29401364&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL373960(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of PL373960A1 publication Critical patent/PL373960A1/pl
Publication of PL210582B1 publication Critical patent/PL210582B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/7455—Thrombomodulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/32—Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Transplantation (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL373960A 2002-05-01 2003-04-30 Przeciwciało przeciwzakrzepowe, kompozycja farmaceutyczna przeciwciała, sposób zabezpieczania przed powstawaniem skrzepu, sposób regulowania odpowiedzi zapalnej, zestaw zawierający przeciwciało oraz kompozycja do terapii genowej i sekwencja polinukleotydowa PL210582B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37656602P 2002-05-01 2002-05-01

Publications (2)

Publication Number Publication Date
PL373960A1 true PL373960A1 (pl) 2005-09-19
PL210582B1 PL210582B1 (pl) 2012-02-29

Family

ID=29401364

Family Applications (2)

Application Number Title Priority Date Filing Date
PL373960A PL210582B1 (pl) 2002-05-01 2003-04-30 Przeciwciało przeciwzakrzepowe, kompozycja farmaceutyczna przeciwciała, sposób zabezpieczania przed powstawaniem skrzepu, sposób regulowania odpowiedzi zapalnej, zestaw zawierający przeciwciało oraz kompozycja do terapii genowej i sekwencja polinukleotydowa
PL03373945A PL373945A1 (pl) 2002-05-01 2003-04-30 Nowe trombomodulinowe białka fuzyjne ukierunkowane na czynnik tkankowy działające jako antykoagulanty

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL03373945A PL373945A1 (pl) 2002-05-01 2003-04-30 Nowe trombomodulinowe białka fuzyjne ukierunkowane na czynnik tkankowy działające jako antykoagulanty

Country Status (29)

Country Link
US (3) US7250168B2 (pl)
EP (2) EP1549341B1 (pl)
JP (2) JP4567437B2 (pl)
KR (2) KR101080587B1 (pl)
CN (2) CN100563709C (pl)
AR (1) AR039515A1 (pl)
AT (2) ATE484524T1 (pl)
AU (2) AU2003225255B2 (pl)
BR (2) BR0304660A (pl)
CA (2) CA2483910A1 (pl)
CR (1) CR7584A (pl)
DE (2) DE60326970D1 (pl)
DK (2) DK1503785T3 (pl)
EC (2) ECSP045467A (pl)
ES (2) ES2354419T3 (pl)
HK (1) HK1080372A1 (pl)
IL (3) IL164733A0 (pl)
MX (2) MXPA04010851A (pl)
NO (2) NO20035849L (pl)
NZ (2) NZ536242A (pl)
PE (1) PE20040597A1 (pl)
PL (2) PL210582B1 (pl)
PT (2) PT1503785E (pl)
RS (2) RS102404A (pl)
RU (2) RU2345789C2 (pl)
TW (1) TWI343388B (pl)
UA (2) UA81114C2 (pl)
WO (2) WO2003092602A2 (pl)
ZA (2) ZA200409692B (pl)

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US7579000B2 (en) 2002-05-01 2009-08-25 Bayer Schering Pharma Ag Tissue factor targeted antibodies as anticoagulants
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WO2008039206A2 (en) * 2005-10-05 2008-04-03 The Trustees Of The University Of Pennsylvania Fusion proteins for inhibition and dissolution of coagulation
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JP2022513332A (ja) * 2018-10-04 2022-02-07 スロムボシス アンド コアグラシヨン アーべー プロテインｓレベルの決定方法
WO2021100794A1 (ja) 2019-11-20 2021-05-27 中外製薬株式会社 抗体含有製剤
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Also Published As

Publication number Publication date
NO20035849L (no) 2004-02-27
IL164732A0 (en) 2005-12-18
KR20050045945A (ko) 2005-05-17
RS102404A (sr) 2006-12-15
MXPA04010795A (es) 2005-03-07
PT1503785E (pt) 2011-01-17
UA81114C2 (en) 2007-12-10
DK1503785T3 (da) 2011-02-07
WO2003093422A2 (en) 2003-11-13
CA2483909A1 (en) 2003-11-13
KR20050045944A (ko) 2005-05-17
PT1549341E (pt) 2009-05-29
JP4460443B2 (ja) 2010-05-12
KR101080587B1 (ko) 2011-11-04
ES2323056T3 (es) 2009-07-06
TWI343388B (en) 2011-06-11
RU2320366C2 (ru) 2008-03-27
HK1080372A1 (zh) 2006-04-28
PL373945A1 (pl) 2005-09-19
IL164733A (en) 2011-05-31
ECSP045468A (es) 2005-01-28
JP2005538046A (ja) 2005-12-15
TW200307043A (en) 2003-12-01
CR7584A (es) 2006-05-30
CA2483910A1 (en) 2003-11-13
EP1503785B1 (en) 2010-10-13
RU2004135306A (ru) 2005-07-10
BR0304660A (pt) 2005-06-07
DE60326970D1 (de) 2009-05-14
CN1665534A (zh) 2005-09-07
AU2003225255A1 (en) 2003-11-17
NO20035848L (no) 2004-02-27
JP4567437B2 (ja) 2010-10-20
EP1503785A4 (en) 2007-02-14
WO2003093422A3 (en) 2004-07-15
DE60334538D1 (de) 2010-11-25
DK1549341T3 (da) 2009-07-06
RU2004135308A (ru) 2005-08-10
US7622457B2 (en) 2009-11-24
WO2003092602A2 (en) 2003-11-13
RS104504A (sr) 2007-02-05
ATE427121T1 (de) 2009-04-15
PL210582B1 (pl) 2012-02-29
NZ536242A (en) 2006-04-28
US20080019985A1 (en) 2008-01-24
EP1549341A4 (en) 2006-10-18
ATE484524T1 (de) 2010-10-15
US7250168B2 (en) 2007-07-31
CN1665526A (zh) 2005-09-07
AU2003225255B2 (en) 2008-07-31
US7622122B2 (en) 2009-11-24
US20040063632A1 (en) 2004-04-01
WO2003092602A3 (en) 2004-08-26
IL164733A0 (en) 2005-12-18
AR039515A1 (es) 2005-02-23
RU2345789C2 (ru) 2009-02-10
BR0304659A (pt) 2004-09-21
ZA200409692B (en) 2006-07-26
EP1549341A2 (en) 2005-07-06
PE20040597A1 (es) 2004-10-06
ES2354419T3 (es) 2011-03-14
EP1503785A2 (en) 2005-02-09
AU2003225256B2 (en) 2009-06-04
CN100563709C (zh) 2009-12-02
US20080020965A1 (en) 2008-01-24
KR101013697B1 (ko) 2011-02-10
JP2005532045A (ja) 2005-10-27
ZA200409694B (en) 2006-02-22
AU2003225256A1 (en) 2003-11-17
CN100412090C (zh) 2008-08-20
UA85996C2 (ru) 2009-03-25
EP1549341B1 (en) 2009-04-01
NZ536243A (en) 2006-06-30
ECSP045467A (es) 2005-01-28
MXPA04010851A (es) 2005-02-14

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