PL363263A1 - Sposób wytwarzania związków imidazolowych - Google Patents

Sposób wytwarzania związków imidazolowych

Info

Publication number
PL363263A1
PL363263A1 PL02363263A PL36326302A PL363263A1 PL 363263 A1 PL363263 A1 PL 363263A1 PL 02363263 A PL02363263 A PL 02363263A PL 36326302 A PL36326302 A PL 36326302A PL 363263 A1 PL363263 A1 PL 363263A1
Authority
PL
Poland
Prior art keywords
preparation
imidazole compounds
imidazole
compounds
Prior art date
Application number
PL02363263A
Other languages
English (en)
Other versions
PL208238B1 (pl
Inventor
Walter Ferdinand Maria Filliers
Rudy Laurent Maria Broeckx
Stefan Marcel Herman Leurs
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of PL363263A1 publication Critical patent/PL363263A1/pl
Publication of PL208238B1 publication Critical patent/PL208238B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Resins (AREA)
PL363263A 2001-03-12 2002-03-05 Sposób wytwarzania 4- (3-chlorofenylo) -6- [ (4-chlorofenylo) hydroksy (1-metylo-1H-imidazol-5-ilo) metylo] -1-metylo-2 (1H) -chinolinonu PL208238B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01200928 2001-03-12
PCT/EP2002/002459 WO2002072574A1 (en) 2001-03-12 2002-03-05 Process for the preparation of imidazole compounds

Publications (2)

Publication Number Publication Date
PL363263A1 true PL363263A1 (pl) 2004-11-15
PL208238B1 PL208238B1 (pl) 2011-04-29

Family

ID=8180004

Family Applications (1)

Application Number Title Priority Date Filing Date
PL363263A PL208238B1 (pl) 2001-03-12 2002-03-05 Sposób wytwarzania 4- (3-chlorofenylo) -6- [ (4-chlorofenylo) hydroksy (1-metylo-1H-imidazol-5-ilo) metylo] -1-metylo-2 (1H) -chinolinonu

Country Status (31)

Country Link
US (1) US6844439B2 (pl)
EP (1) EP1373255B1 (pl)
JP (1) JP4257698B2 (pl)
KR (1) KR100849042B1 (pl)
CN (1) CN1246318C (pl)
AR (1) AR035944A1 (pl)
AT (1) ATE287882T1 (pl)
AU (1) AU2002253101B2 (pl)
BR (1) BRPI0208075B8 (pl)
CA (1) CA2438421C (pl)
CZ (1) CZ300622B6 (pl)
DE (1) DE60202755T2 (pl)
DK (1) DK1373255T3 (pl)
EA (1) EA006770B1 (pl)
EE (1) EE05247B1 (pl)
ES (1) ES2236505T3 (pl)
HR (1) HRP20030695B1 (pl)
HU (1) HU230282B1 (pl)
IL (2) IL157839A0 (pl)
MX (1) MXPA03008205A (pl)
MY (1) MY124838A (pl)
NO (1) NO324954B1 (pl)
NZ (1) NZ528620A (pl)
PL (1) PL208238B1 (pl)
PT (1) PT1373255E (pl)
SI (1) SI1373255T1 (pl)
SK (1) SK287807B6 (pl)
TW (1) TWI249532B (pl)
UA (1) UA74871C2 (pl)
WO (1) WO2002072574A1 (pl)
ZA (1) ZA200307117B (pl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2291455T3 (es) 2001-03-12 2008-03-01 Avanir Pharmaceuticals Compuestos de bencimidazol para modular ige e inhibir la proliferacion celular.
WO2004024655A2 (en) 2002-09-12 2004-03-25 Avanir Pharmaceuticals Phenyl-indole compounds for modulating ige and inhibiting cellular proliferation
TWI276631B (en) 2002-09-12 2007-03-21 Avanir Pharmaceuticals Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
US20060106060A1 (en) * 2004-03-18 2006-05-18 The Brigham And Women's Hospital, Inc. Methods for the treatment of synucleinopathies (Lansbury)
US7572916B2 (en) 2004-05-03 2009-08-11 Janssen Pharmaceutica Nv Diastereoselective synthesis process with 6-bromo-4-(3-chlorophenyl)-2-methoxy-quinoline
CN100567292C (zh) * 2004-05-03 2009-12-09 詹森药业有限公司 制备咪唑化合物的非对映选择性合成方法
EP1758885B1 (en) 2004-05-03 2008-06-18 Janssen Pharmaceutica N.V. Diastereoselective addition of lithiated n-methylimidazole on sulfinimines
EP1968591A4 (en) 2005-12-23 2010-02-17 Link Medicine Corp TREATMENT OF SYNUCLEINOPATHIES
US8232402B2 (en) * 2008-03-12 2012-07-31 Link Medicine Corporation Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications
KR101044430B1 (ko) * 2009-09-25 2011-06-27 듀오백코리아 주식회사 요추받이를 포함하는 의자의 등 지지 장치
KR101107900B1 (ko) * 2009-10-21 2012-01-25 성용기업 주식회사 의자용 허리지지장치
EA201890512A1 (ru) 2015-08-17 2018-09-28 Кура Онколоджи, Инк. Способы лечения пациентов со злокачественными опухолями с использованием ингибиторов фарнезилтрансферазы
RS61745B1 (sr) 2016-11-03 2021-05-31 Kura Oncology Inc Inhibitori farneziltransferaze za upotrebu u tretiranju kancera
WO2018103027A1 (zh) * 2016-12-08 2018-06-14 杭州领业医药科技有限公司 替吡法尼的晶型及其制备方法及药物组合物
EP3793966A1 (en) * 2018-05-18 2021-03-24 Kura Oncology, Inc. Synthesis of tipifarnib

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW349948B (en) 1995-10-31 1999-01-11 Janssen Pharmaceutica Nv Farnesyl transferase inhibiting 2-quinolone derivatives
EE03484B1 (et) * 1995-12-08 2001-08-15 Janssen Pharmaceutica N.V. Farnesüülproteiintransferaasi inhibeerivad (5-imidasolüül)metüül-2-kinolinooni derivaadid ja nende kasutamine
TW591030B (en) 1997-03-10 2004-06-11 Janssen Pharmaceutica Nv Farnesyl transferase inhibiting 1,8-annelated quinolinone derivatives substituted with N- or C-linked imidazoles
BR9809398A (pt) * 1997-04-25 2000-06-13 Janssen Pharmaceutica Nv Quinazolinonas que inibem a farnesil transferase
ATE289602T1 (de) 1998-08-27 2005-03-15 Pfizer Prod Inc Quinolin-2-on-derivate verwendbar als antikrebsmittel
TR200101343T2 (tr) * 1998-08-27 2001-09-21 Pfizer Products Inc. Kansere karşı kullanılan maddeler olarak alkinil-ikame edilmiş kinolin-2-on türevleri

Also Published As

Publication number Publication date
JP4257698B2 (ja) 2009-04-22
ZA200307117B (en) 2004-09-13
SI1373255T1 (pl) 2005-08-31
HUP0303443A3 (en) 2012-09-28
CA2438421C (en) 2010-05-18
SK287807B6 (sk) 2011-10-04
PT1373255E (pt) 2005-05-31
US20040138256A1 (en) 2004-07-15
HRP20030695A2 (en) 2005-02-28
EP1373255A1 (en) 2004-01-02
KR100849042B1 (ko) 2008-07-29
NO20034003D0 (no) 2003-09-10
NO324954B1 (no) 2008-01-14
WO2002072574A1 (en) 2002-09-19
SK12462003A3 (sk) 2004-06-08
UA74871C2 (en) 2006-02-15
EA006770B1 (ru) 2006-04-28
HU230282B1 (hu) 2015-12-28
AU2002253101B2 (en) 2007-08-09
HK1063315A1 (zh) 2004-12-24
MXPA03008205A (es) 2004-01-29
IL157839A (en) 2008-07-08
ATE287882T1 (de) 2005-02-15
BRPI0208075B1 (pt) 2018-02-14
DE60202755D1 (de) 2005-03-03
BRPI0208075B8 (pt) 2021-05-25
JP2004523575A (ja) 2004-08-05
BR0208075A (pt) 2004-03-02
AR035944A1 (es) 2004-07-28
US6844439B2 (en) 2005-01-18
KR20030079971A (ko) 2003-10-10
CZ20032704A3 (en) 2004-03-17
DK1373255T3 (da) 2005-05-23
NZ528620A (en) 2005-01-28
PL208238B1 (pl) 2011-04-29
CA2438421A1 (en) 2002-09-19
IL157839A0 (en) 2004-03-28
EE05247B1 (et) 2009-12-15
TWI249532B (en) 2006-02-21
NO20034003L (no) 2003-10-22
DE60202755T2 (de) 2006-03-30
EA200300998A1 (ru) 2004-02-26
HUP0303443A2 (hu) 2004-01-28
CN1246318C (zh) 2006-03-22
MY124838A (en) 2006-07-31
ES2236505T3 (es) 2005-07-16
EP1373255B1 (en) 2005-01-26
CN1496363A (zh) 2004-05-12
CZ300622B6 (cs) 2009-07-01
EE200300442A (et) 2003-12-15
HRP20030695B1 (hr) 2011-07-31

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