PL360710A1 - Podstawione pochodne benzenu lub ich sole - Google Patents
Podstawione pochodne benzenu lub ich soleInfo
- Publication number
- PL360710A1 PL360710A1 PL01360710A PL36071001A PL360710A1 PL 360710 A1 PL360710 A1 PL 360710A1 PL 01360710 A PL01360710 A PL 01360710A PL 36071001 A PL36071001 A PL 36071001A PL 360710 A1 PL360710 A1 PL 360710A1
- Authority
- PL
- Poland
- Prior art keywords
- salts
- substituted benzene
- benzene derivatives
- carboxanilide
- pyridyl
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title abstract 2
- 125000001997 phenyl group Chemical class [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000005189 Embolism Diseases 0.000 abstract 1
- 108010074860 Factor Xa Proteins 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 230000002429 anti-coagulating effect Effects 0.000 abstract 1
- 239000003146 anticoagulant agent Substances 0.000 abstract 1
- 229940127219 anticoagulant drug Drugs 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Fats And Perfumes (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000356146 | 2000-11-22 | ||
| JP2000390321 | 2000-12-22 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL360710A1 true PL360710A1 (pl) | 2004-09-20 |
| PL204898B1 PL204898B1 (pl) | 2010-02-26 |
Family
ID=26604464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL360710A PL204898B1 (pl) | 2000-11-22 | 2001-11-21 | Podstawiona pochodna benzenu i zawierająca ja kompozycja farmaceutyczna oraz jej zastosowanie |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US7504417B2 (pl) |
| EP (1) | EP1336605B1 (pl) |
| JP (1) | JP3903920B2 (pl) |
| KR (1) | KR100863923B1 (pl) |
| CN (1) | CN1283626C (pl) |
| AT (1) | ATE323071T1 (pl) |
| AU (2) | AU2002224064B2 (pl) |
| CA (1) | CA2424522C (pl) |
| DE (1) | DE60118774T2 (pl) |
| DK (1) | DK1336605T3 (pl) |
| ES (1) | ES2260336T3 (pl) |
| HU (1) | HUP0400558A3 (pl) |
| MX (1) | MXPA03003572A (pl) |
| PL (1) | PL204898B1 (pl) |
| PT (1) | PT1336605E (pl) |
| RU (1) | RU2276137C2 (pl) |
| WO (1) | WO2002042270A1 (pl) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI290136B (en) | 2000-04-05 | 2007-11-21 | Daiichi Seiyaku Co | Ethylenediamine derivatives |
| US7365205B2 (en) | 2001-06-20 | 2008-04-29 | Daiichi Sankyo Company, Limited | Diamine derivatives |
| SE0102764D0 (sv) | 2001-08-17 | 2001-08-17 | Astrazeneca Ab | Compounds |
| BR0307266A (pt) * | 2002-01-31 | 2004-12-07 | Morphochem Ag Komb Chemie | Compostos que inibem a atividade do fator xa |
| GB0226930D0 (en) | 2002-11-19 | 2002-12-24 | Astrazeneca Ab | Chemical compounds |
| KR20070007104A (ko) * | 2004-02-18 | 2007-01-12 | 아스트라제네카 아베 | 화합물 |
| DE602005013491D1 (de) * | 2004-02-18 | 2009-05-07 | Astrazeneca Ab | Benzamidderivate und deren verwendung als glucokinaseaktivierende mittel |
| TW200600086A (en) | 2004-06-05 | 2006-01-01 | Astrazeneca Ab | Chemical compound |
| KR20070085371A (ko) * | 2004-10-16 | 2007-08-27 | 아스트라제네카 아베 | 페녹시 벤즈아미드 화합물의 제조 방법 |
| GB0423043D0 (en) * | 2004-10-16 | 2004-11-17 | Astrazeneca Ab | Compounds |
| JP4900238B2 (ja) | 2005-02-02 | 2012-03-21 | 味の素株式会社 | 新規ベンズアミジン化合物 |
| EP1891069A1 (en) * | 2005-05-24 | 2008-02-27 | AstraZeneca AB | 2-phenyl substituted imidazol [4,5b]pyridine/ pyrazine and purine derivatives as glucokinase modulators |
| TW200714597A (en) * | 2005-05-27 | 2007-04-16 | Astrazeneca Ab | Chemical compounds |
| US20110053910A1 (en) * | 2005-07-09 | 2011-03-03 | Mckerrecher Darren | 2 -heterocyclyloxybenzoyl amino heterocyclyl compounds as modulators of glucokinase for the treatment of type 2 diabetes |
| US20080234273A1 (en) * | 2005-07-09 | 2008-09-25 | Mckerrecher Darren | Heteroaryl Benzamide Derivatives for Use as Glk Activators in the Treatment of Diabetes |
| CA2614746C (en) * | 2005-07-09 | 2011-05-10 | Astrazeneca Ab | Heteroaryl benzamide derivatives for use as glk activators in the treatment of diabetes |
| US9202182B2 (en) * | 2005-08-11 | 2015-12-01 | International Business Machines Corporation | Method and system for analyzing business architecture |
| TW200734304A (en) * | 2005-11-08 | 2007-09-16 | Astellas Pharma Inc | Benzene derivative or salt thereof |
| TW200738621A (en) | 2005-11-28 | 2007-10-16 | Astrazeneca Ab | Chemical process |
| TW200825063A (en) * | 2006-10-23 | 2008-06-16 | Astrazeneca Ab | Chemical compounds |
| SA07280576B1 (ar) * | 2006-10-26 | 2011-06-22 | استرازينيكا ايه بي | مركبات بنزويل أمينو سيكليل غير متجانسة بأعتبارها عوامل منشطة للجلوكوكيناز |
| UY30822A1 (es) * | 2006-12-21 | 2008-07-31 | Astrazeneca Ab | Fnueva forma cristalina de 3-{[5-azetidin-1-ylcabonyl)pyrazin-2-yl]oxy}-5-[1-methylethyloxy]-n-1h-pyrazol-3-ylbenzamida, composiciones conteniéndola, procesos de preparacion y aplicaciones |
| JP2010120852A (ja) * | 2007-03-09 | 2010-06-03 | Daiichi Sankyo Co Ltd | 新規なジアミド誘導体 |
| WO2008135524A2 (en) * | 2007-05-02 | 2008-11-13 | Boehringer Ingelheim International Gmbh | Substituted anthranilamides and analogues, manufacturing and use thereof as medicaments |
| EP2311810A4 (en) | 2008-07-11 | 2012-04-04 | Ajinomoto Kk | AMIDINE DERIVATIVE |
| CA2732165A1 (en) | 2008-08-04 | 2010-02-11 | Astrazeneca Ab | Therapeutic agents 414 |
| TW201021832A (en) * | 2008-09-30 | 2010-06-16 | Astellas Pharma Inc | Pharmaceutical composition for oral administration |
| GB0902434D0 (en) * | 2009-02-13 | 2009-04-01 | Astrazeneca Ab | Chemical process |
| GB0902406D0 (en) * | 2009-02-13 | 2009-04-01 | Astrazeneca Ab | Crystalline polymorphic form |
| AR076220A1 (es) | 2009-04-09 | 2011-05-26 | Astrazeneca Ab | Derivados de pirazol [4,5 - e] pirimidina |
| AR076221A1 (es) * | 2009-04-09 | 2011-05-26 | Astrazeneca Ab | Derivado de pirazol [4,5-e] pirimidina y su uso para tratar diabetes y obesidad |
| DE102014108210A1 (de) | 2014-06-11 | 2015-12-17 | Dietrich Gulba | Rodentizid |
| EP4070658A1 (de) | 2021-04-06 | 2022-10-12 | BIORoxx GmbH | Verwendung von blutgerinnungshemmenden verbindungen als rodentizide |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04304012A (ja) * | 1991-03-31 | 1992-10-27 | Sony Corp | フイルタ回路 |
| US5417200A (en) * | 1994-01-25 | 1995-05-23 | Wasielewski; John J. | Lantern cooker |
| ZA951617B (en) * | 1994-03-04 | 1997-02-27 | Lilly Co Eli | Antithrombotic agents. |
| DE69529770T2 (de) | 1994-12-02 | 2003-12-24 | Yamanouchi Pharmaceutical Co., Ltd. | Neues amidinonaphthylderivat oder dessen salz |
| EP1014962A4 (en) | 1997-06-26 | 2007-06-27 | Lilly Co Eli | ANTITHROMBOTIC AGENTS |
| IL133627A0 (en) | 1997-06-26 | 2001-04-30 | Lilly Co Eli | Antithrombotic agents |
| US6372759B1 (en) | 1997-06-26 | 2002-04-16 | Eli Lilly And Company | Antithrombotic agents |
| IL133625A0 (en) | 1997-06-26 | 2001-04-30 | Lilly Co Eli | Antithrombotic agents |
| US6140351A (en) | 1997-12-19 | 2000-10-31 | Berlex Laboratories, Inc. | Ortho-anthranilamide derivatives as anti-coagulants |
| EP1040108B1 (en) | 1997-12-19 | 2004-02-25 | Schering Aktiengesellschaft | Ortho-anthranilamide derivatives as anti-coagulants |
| AU2074699A (en) | 1998-01-26 | 1999-08-09 | Yamanouchi Pharmaceutical Co., Ltd. | Novel benzene-fused heterocyclic derivatives or salts thereof |
| AU2054700A (en) * | 1998-12-23 | 2000-07-31 | Eli Lilly And Company | Antithrombotic amides |
| EP1140905B1 (en) | 1998-12-23 | 2003-05-14 | Eli Lilly And Company | Heteroaromatic amides as inhibitor of factor xa |
| ATE272633T1 (de) | 1998-12-23 | 2004-08-15 | Lilly Co Eli | Aromatische amiden |
| JP4390024B2 (ja) | 1999-04-23 | 2009-12-24 | アステラス製薬株式会社 | 新規なジアゼパン誘導体又はその塩 |
| JP2003509412A (ja) | 1999-09-17 | 2003-03-11 | シーオーアール セラピューティクス インコーポレイテッド | Ｘａ因子阻害剤 |
| US6632815B2 (en) | 1999-09-17 | 2003-10-14 | Millennium Pharmaceuticals, Inc. | Inhibitors of factor Xa |
| DE60040676D1 (de) | 1999-09-17 | 2008-12-11 | Millennium Pharm Inc | BENZAMIDE UND ÄHNLICHE INHIBITOREN VON FAKTOR Xa |
| AU2001250783A1 (en) | 2000-02-29 | 2001-09-12 | Cor Therapeutics, Inc. | Benzamides and related inhibitors of factor xa |
| AU776053B2 (en) | 2000-03-31 | 2004-08-26 | Astellas Pharma Inc. | Diazepan derivatives or salts thereof |
| US7160878B2 (en) | 2000-07-27 | 2007-01-09 | Eli Lilly And Company | Substituted heterocyclic amides |
| AU2001297648A1 (en) | 2000-11-28 | 2002-08-28 | Eli Lilly And Company | Substituted carboxamides as inhibitors of factor xa |
-
2001
- 2001-11-21 PT PT01997188T patent/PT1336605E/pt unknown
- 2001-11-21 ES ES01997188T patent/ES2260336T3/es not_active Expired - Lifetime
- 2001-11-21 EP EP01997188A patent/EP1336605B1/en not_active Expired - Lifetime
- 2001-11-21 MX MXPA03003572A patent/MXPA03003572A/es active IP Right Grant
- 2001-11-21 WO PCT/JP2001/010176 patent/WO2002042270A1/ja not_active Ceased
- 2001-11-21 DK DK01997188T patent/DK1336605T3/da active
- 2001-11-21 CA CA002424522A patent/CA2424522C/en not_active Expired - Fee Related
- 2001-11-21 AU AU2002224064A patent/AU2002224064B2/en not_active Ceased
- 2001-11-21 PL PL360710A patent/PL204898B1/pl not_active IP Right Cessation
- 2001-11-21 DE DE60118774T patent/DE60118774T2/de not_active Expired - Lifetime
- 2001-11-21 JP JP2002544406A patent/JP3903920B2/ja not_active Expired - Fee Related
- 2001-11-21 US US10/399,625 patent/US7504417B2/en not_active Expired - Fee Related
- 2001-11-21 CN CNB018192564A patent/CN1283626C/zh not_active Expired - Fee Related
- 2001-11-21 AU AU2406402A patent/AU2406402A/xx active Pending
- 2001-11-21 RU RU2003115092/04A patent/RU2276137C2/ru not_active IP Right Cessation
- 2001-11-21 KR KR1020037006813A patent/KR100863923B1/ko not_active Expired - Fee Related
- 2001-11-21 AT AT01997188T patent/ATE323071T1/de active
- 2001-11-21 HU HU0400558A patent/HUP0400558A3/hu unknown
-
2009
- 2009-01-20 US US12/356,376 patent/US7786106B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002042270A1 (en) | 2002-05-30 |
| EP1336605A1 (en) | 2003-08-20 |
| HUP0400558A3 (en) | 2010-03-29 |
| RU2276137C2 (ru) | 2006-05-10 |
| EP1336605B1 (en) | 2006-04-12 |
| ES2260336T3 (es) | 2006-11-01 |
| EP1336605A4 (en) | 2004-01-28 |
| PL204898B1 (pl) | 2010-02-26 |
| US7504417B2 (en) | 2009-03-17 |
| CN1283626C (zh) | 2006-11-08 |
| PT1336605E (pt) | 2006-06-30 |
| ATE323071T1 (de) | 2006-04-15 |
| CN1476433A (zh) | 2004-02-18 |
| JP3903920B2 (ja) | 2007-04-11 |
| KR20030060944A (ko) | 2003-07-16 |
| AU2002224064B2 (en) | 2005-12-08 |
| HUP0400558A2 (hu) | 2004-06-28 |
| US7786106B2 (en) | 2010-08-31 |
| AU2406402A (en) | 2002-06-03 |
| US20090137498A1 (en) | 2009-05-28 |
| CA2424522C (en) | 2009-12-29 |
| MXPA03003572A (es) | 2003-07-14 |
| CA2424522A1 (en) | 2003-03-31 |
| DE60118774D1 (de) | 2006-05-24 |
| KR100863923B1 (ko) | 2008-10-17 |
| US20040077555A1 (en) | 2004-04-22 |
| JPWO2002042270A1 (ja) | 2004-03-25 |
| DE60118774T2 (de) | 2007-03-15 |
| DK1336605T3 (da) | 2006-06-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| LAPS | Decisions on the lapse of the protection rights |
Effective date: 20131121 |