PT874843E - 4-(1h-benzimidazol-2-il)¬1,4|diazepinos substituidos uteis para o tratamento de doencas alergicas - Google Patents
4-(1h-benzimidazol-2-il)¬1,4|diazepinos substituidos uteis para o tratamento de doencas alergicasInfo
- Publication number
- PT874843E PT874843E PT96944267T PT96944267T PT874843E PT 874843 E PT874843 E PT 874843E PT 96944267 T PT96944267 T PT 96944267T PT 96944267 T PT96944267 T PT 96944267T PT 874843 E PT874843 E PT 874843E
- Authority
- PT
- Portugal
- Prior art keywords
- uzide
- diazepins
- benzimidazol
- substituted
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58000495A | 1995-12-20 | 1995-12-20 | |
| US73641196A | 1996-10-24 | 1996-10-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT874843E true PT874843E (pt) | 2002-12-31 |
Family
ID=27077922
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT96944267T PT874843E (pt) | 1995-12-20 | 1996-12-04 | 4-(1h-benzimidazol-2-il)¬1,4|diazepinos substituidos uteis para o tratamento de doencas alergicas |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0874843B1 (pt) |
| JP (1) | JP2000500772A (pt) |
| KR (1) | KR20000064487A (pt) |
| CN (1) | CN1080262C (pt) |
| AR (1) | AR005120A1 (pt) |
| AT (1) | ATE221883T1 (pt) |
| AU (1) | AU707914B2 (pt) |
| BR (1) | BR9612074A (pt) |
| CA (1) | CA2241827C (pt) |
| DE (1) | DE69622889T2 (pt) |
| DK (1) | DK0874843T3 (pt) |
| ES (1) | ES2177827T3 (pt) |
| HK (1) | HK1017684A1 (pt) |
| IL (1) | IL125002A0 (pt) |
| MX (1) | MX9804991A (pt) |
| NO (1) | NO316932B1 (pt) |
| NZ (1) | NZ325581A (pt) |
| PT (1) | PT874843E (pt) |
| TW (1) | TW335395B (pt) |
| WO (1) | WO1997022604A1 (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6423704B2 (en) | 1995-12-20 | 2002-07-23 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases |
| US6194406B1 (en) * | 1995-12-20 | 2001-02-27 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease |
| US6552188B2 (en) * | 2001-06-29 | 2003-04-22 | Kowa Co., Ltd. | Unsymmetrical cyclic diamine compound |
| ATE397586T1 (de) | 2004-05-07 | 2008-06-15 | Janssen Pharmaceutica Nv | Adamantyl pyrrolidin-2-on-derivate als 11-beta hydroxysteroid dehydrogenas inhibitoren |
| US9012494B2 (en) | 2004-05-07 | 2015-04-21 | Janssen Pharmaceutica N.V. | Pyrrolidin-2-one and piperidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors |
| MY141198A (en) | 2004-08-30 | 2010-03-31 | Janssen Pharmaceutica Nv | Tricyclic adamantylamide derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors |
| KR101197674B1 (ko) | 2004-08-30 | 2012-11-07 | 얀센 파마슈티카 엔.브이. | １１-베타 하이드록시스테로이드 탈수소효소 저해제로서의 ｎ-2 아다만타닐-２-페녹시-아세트아미드 유도체 |
| DE602005017159D1 (de) | 2004-08-30 | 2009-11-26 | Janssen Pharmaceutica Nv | Oxysteroid-dehydrogenase-inhibitoren |
| EP2117538A1 (en) | 2007-01-24 | 2009-11-18 | Glaxo Group Limited | Pharmaceutical compositions comprising 2-methoxy-5- (5-trifluoromethyl-tetrazol-i-yl-benzyl) - (2s-phenyl-piperidin-3s-yl-) |
| CN105646306B (zh) * | 2015-12-11 | 2020-06-30 | 广东莱佛士制药技术有限公司 | 一种4-甲硫基苯乙酸的制备方法 |
| WO2020113094A1 (en) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2676055B1 (fr) * | 1991-05-03 | 1993-09-03 | Sanofi Elf | Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| FR2676054B1 (fr) * | 1991-05-03 | 1993-09-03 | Sanofi Elf | Nouveaux composes n-alkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| CN1081635C (zh) * | 1993-05-06 | 2002-03-27 | 默里尔药物公司 | 取代的吡咯烷 －3－基－烷基－哌啶 |
| US5624948A (en) * | 1993-05-20 | 1997-04-29 | Kissei Pharmaceutical Co., Ltd. | 1-(2-benzimidazolyl)-1,5-diazacyclooctane compounds |
| CN1067385C (zh) * | 1994-08-25 | 2001-06-20 | 默里尔药物公司 | 用于治疗变应性疾病的新的取代的哌啶类化合物 |
-
1996
- 1996-12-04 KR KR1019980704684A patent/KR20000064487A/ko active IP Right Grant
- 1996-12-04 ES ES96944267T patent/ES2177827T3/es not_active Expired - Lifetime
- 1996-12-04 DK DK96944267T patent/DK0874843T3/da active
- 1996-12-04 AU AU14119/97A patent/AU707914B2/en not_active Ceased
- 1996-12-04 BR BR9612074A patent/BR9612074A/pt unknown
- 1996-12-04 AT AT96944267T patent/ATE221883T1/de not_active IP Right Cessation
- 1996-12-04 CN CN96199141A patent/CN1080262C/zh not_active Expired - Fee Related
- 1996-12-04 IL IL12500296A patent/IL125002A0/xx unknown
- 1996-12-04 PT PT96944267T patent/PT874843E/pt unknown
- 1996-12-04 WO PCT/US1996/019524 patent/WO1997022604A1/en not_active Application Discontinuation
- 1996-12-04 NZ NZ325581A patent/NZ325581A/xx unknown
- 1996-12-04 CA CA002241827A patent/CA2241827C/en not_active Expired - Fee Related
- 1996-12-04 EP EP96944267A patent/EP0874843B1/en not_active Expired - Lifetime
- 1996-12-04 DE DE69622889T patent/DE69622889T2/de not_active Expired - Fee Related
- 1996-12-04 JP JP9522863A patent/JP2000500772A/ja active Pending
- 1996-12-18 AR ARP960105741A patent/AR005120A1/es active IP Right Grant
- 1996-12-21 TW TW085115838A patent/TW335395B/zh active
-
1998
- 1998-06-19 MX MX9804991A patent/MX9804991A/es not_active IP Right Cessation
- 1998-06-19 NO NO19982867A patent/NO316932B1/no not_active IP Right Cessation
-
1999
- 1999-07-05 HK HK99102816A patent/HK1017684A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ325581A (en) | 2000-03-27 |
| ATE221883T1 (de) | 2002-08-15 |
| DK0874843T3 (da) | 2002-11-25 |
| ES2177827T3 (es) | 2002-12-16 |
| IL125002A0 (en) | 1999-01-26 |
| DE69622889D1 (de) | 2002-09-12 |
| CN1207097A (zh) | 1999-02-03 |
| MX9804991A (es) | 1998-09-30 |
| AU1411997A (en) | 1997-07-14 |
| NO982867L (no) | 1998-08-19 |
| NO982867D0 (no) | 1998-06-19 |
| BR9612074A (pt) | 1999-03-30 |
| NO316932B1 (no) | 2004-06-28 |
| WO1997022604A1 (en) | 1997-06-26 |
| KR20000064487A (ko) | 2000-11-06 |
| CA2241827C (en) | 2002-04-30 |
| EP0874843B1 (en) | 2002-08-07 |
| CA2241827A1 (en) | 1997-06-26 |
| JP2000500772A (ja) | 2000-01-25 |
| TW335395B (en) | 1998-07-01 |
| DE69622889T2 (de) | 2003-04-10 |
| CN1080262C (zh) | 2002-03-06 |
| EP0874843A1 (en) | 1998-11-04 |
| AU707914B2 (en) | 1999-07-22 |
| HK1017684A1 (en) | 1999-11-26 |
| AR005120A1 (es) | 1999-04-14 |
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