NO982867L - Nye substituerte 4-(1H-benzimidazol-2-yl)£1,4|diazepaner som er anvendbare for behandling av allergiske sykdommer - Google Patents

Nye substituerte 4-(1H-benzimidazol-2-yl)£1,4|diazepaner som er anvendbare for behandling av allergiske sykdommer

Info

Publication number
NO982867L
NO982867L NO982867A NO982867A NO982867L NO 982867 L NO982867 L NO 982867L NO 982867 A NO982867 A NO 982867A NO 982867 A NO982867 A NO 982867A NO 982867 L NO982867 L NO 982867L
Authority
NO
Norway
Prior art keywords
benzimidazol
treatment
allergic diseases
newly substituted
diazepanes
Prior art date
Application number
NO982867A
Other languages
English (en)
Other versions
NO316932B1 (no
NO982867D0 (no
Inventor
Elizabeth Mary Kudlacz
George Daniel Maynard
Timothy Paul Burkholder
Larry Don Bratton
Christopher Robin Dalton
Braulio Santiago
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of NO982867D0 publication Critical patent/NO982867D0/no
Publication of NO982867L publication Critical patent/NO982867L/no
Publication of NO316932B1 publication Critical patent/NO316932B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO19982867A 1995-12-20 1998-06-19 Nye, substituerte 4-(1H-benzimidazol-2-yl)[1,4]diazepaner som er anvendbare for behandling av allergiske sykdommer, fremgangsmate for fremstilling av disse, samt farmasoytisk preparat inneholdende disse NO316932B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58000495A 1995-12-20 1995-12-20
US73641196A 1996-10-24 1996-10-24
PCT/US1996/019524 WO1997022604A1 (en) 1995-12-20 1996-12-04 Novel substituted 4-(1h-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases

Publications (3)

Publication Number Publication Date
NO982867D0 NO982867D0 (no) 1998-06-19
NO982867L true NO982867L (no) 1998-08-19
NO316932B1 NO316932B1 (no) 2004-06-28

Family

ID=27077922

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19982867A NO316932B1 (no) 1995-12-20 1998-06-19 Nye, substituerte 4-(1H-benzimidazol-2-yl)[1,4]diazepaner som er anvendbare for behandling av allergiske sykdommer, fremgangsmate for fremstilling av disse, samt farmasoytisk preparat inneholdende disse

Country Status (20)

Country Link
EP (1) EP0874843B1 (no)
JP (1) JP2000500772A (no)
KR (1) KR20000064487A (no)
CN (1) CN1080262C (no)
AR (1) AR005120A1 (no)
AT (1) ATE221883T1 (no)
AU (1) AU707914B2 (no)
BR (1) BR9612074A (no)
CA (1) CA2241827C (no)
DE (1) DE69622889T2 (no)
DK (1) DK0874843T3 (no)
ES (1) ES2177827T3 (no)
HK (1) HK1017684A1 (no)
IL (1) IL125002A0 (no)
MX (1) MX9804991A (no)
NO (1) NO316932B1 (no)
NZ (1) NZ325581A (no)
PT (1) PT874843E (no)
TW (1) TW335395B (no)
WO (1) WO1997022604A1 (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6194406B1 (en) * 1995-12-20 2001-02-27 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
US6423704B2 (en) 1995-12-20 2002-07-23 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
US6552188B2 (en) * 2001-06-29 2003-04-22 Kowa Co., Ltd. Unsymmetrical cyclic diamine compound
MXPA06012929A (es) 2004-05-07 2007-01-26 Janssen Pharmaceutica Nv Derivados de adamantil pirrolidin-2-ona como inhibidores de 11-beta hidroxiesteroide deshidrogenasa.
WO2005108360A1 (en) 2004-05-07 2005-11-17 Janssen Pharmaceutica N.V. Pyrrolidin-2-one and piperidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
DE602005017159D1 (de) 2004-08-30 2009-11-26 Janssen Pharmaceutica Nv Oxysteroid-dehydrogenase-inhibitoren
DE602005018509D1 (de) 2004-08-30 2010-02-04 Janssen Pharmaceutica Nv N-2-adamantanyl-2-phenoxy-acetamid-derivate als 11-betahydroxysteroid-dehydrogenase-hemmer
WO2006024628A1 (en) 2004-08-30 2006-03-09 Janssen Pharmaceutica N.V. Tricyclic lactam derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
WO2008090117A1 (en) 2007-01-24 2008-07-31 Glaxo Group Limited Pharmaceutical compositions comprising 3, 5-diamin0-6- (2, 3-dichl0phenyl) -l, 2, 4-triazine or r (-) -2, 4-diamino-5- (2, 3-dichlorophenyl) -6-fluoromethyl pyrimidine and an nk1
CN105646306B (zh) * 2015-12-11 2020-06-30 广东莱佛士制药技术有限公司 一种4-甲硫基苯乙酸的制备方法
CA3121202A1 (en) 2018-11-30 2020-06-04 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2676054B1 (fr) * 1991-05-03 1993-09-03 Sanofi Elf Nouveaux composes n-alkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2676055B1 (fr) * 1991-05-03 1993-09-03 Sanofi Elf Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
CN1081635C (zh) * 1993-05-06 2002-03-27 默里尔药物公司 取代的吡咯烷 -3-基-烷基-哌啶
CA2161876A1 (en) * 1993-05-20 1994-12-08 Den-Ichi Momose 1-(2-benzimidazolyl)-1,5-diazacyclooctane compounds
CA2198084C (en) * 1994-08-25 2000-03-28 Timothy P. Burkholder Novel substituted piperidines useful for the treatment of allergic diseases

Also Published As

Publication number Publication date
CN1207097A (zh) 1999-02-03
PT874843E (pt) 2002-12-31
AR005120A1 (es) 1999-04-14
DE69622889D1 (de) 2002-09-12
DK0874843T3 (da) 2002-11-25
NO316932B1 (no) 2004-06-28
CN1080262C (zh) 2002-03-06
EP0874843B1 (en) 2002-08-07
WO1997022604A1 (en) 1997-06-26
BR9612074A (pt) 1999-03-30
EP0874843A1 (en) 1998-11-04
AU1411997A (en) 1997-07-14
HK1017684A1 (en) 1999-11-26
JP2000500772A (ja) 2000-01-25
CA2241827C (en) 2002-04-30
CA2241827A1 (en) 1997-06-26
KR20000064487A (ko) 2000-11-06
IL125002A0 (en) 1999-01-26
NZ325581A (en) 2000-03-27
AU707914B2 (en) 1999-07-22
DE69622889T2 (de) 2003-04-10
ATE221883T1 (de) 2002-08-15
TW335395B (en) 1998-07-01
NO982867D0 (no) 1998-06-19
ES2177827T3 (es) 2002-12-16
MX9804991A (es) 1998-09-30

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