ITMI951587A0 - Epimeri del (22rs)-n-(1,1,1-trifluoro-2-fenilprop-2-il)-3-osso -4-aza-5-afa-androst-1-ene-17beta-carbossammide - Google Patents

Epimeri del (22rs)-n-(1,1,1-trifluoro-2-fenilprop-2-il)-3-osso -4-aza-5-afa-androst-1-ene-17beta-carbossammide

Info

Publication number
ITMI951587A0
ITMI951587A0 ITMI951587A ITMI951587A ITMI951587A0 IT MI951587 A0 ITMI951587 A0 IT MI951587A0 IT MI951587 A ITMI951587 A IT MI951587A IT MI951587 A ITMI951587 A IT MI951587A IT MI951587 A0 ITMI951587 A0 IT MI951587A0
Authority
IT
Italy
Prior art keywords
17beta
afa
androst
phenylprop
epimers
Prior art date
Application number
ITMI951587A
Other languages
English (en)
Original Assignee
Pharmacia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Spa filed Critical Pharmacia Spa
Publication of ITMI951587A0 publication Critical patent/ITMI951587A0/it
Priority to IT95MI001587A priority Critical patent/IT1275594B1/it
Priority to AU64183/96A priority patent/AU6418396A/en
Priority to PCT/EP1996/002830 priority patent/WO1997004002A1/en
Priority to PL96319351A priority patent/PL319351A1/xx
Priority to MX9701948A priority patent/MX9701948A/es
Priority to IL12034396A priority patent/IL120343A0/xx
Priority to EP96923968A priority patent/EP0782582A1/en
Priority to JP9506217A priority patent/JPH10506411A/ja
Priority to CA002199273A priority patent/CA2199273A1/en
Priority to HU9702465A priority patent/HUP9702465A3/hu
Priority to KR1019970701797A priority patent/KR970706298A/ko
Priority to CN96190785A priority patent/CN1159195A/zh
Priority to BR9606527A priority patent/BR9606527A/pt
Priority to ZA965678A priority patent/ZA965678B/xx
Priority to ARP960103652A priority patent/AR003967A1/es
Publication of ITMI951587A1 publication Critical patent/ITMI951587A1/it
Priority to NO971196A priority patent/NO971196L/no
Priority to EA199700045A priority patent/EA199700045A1/ru
Application granted granted Critical
Publication of IT1275594B1 publication Critical patent/IT1275594B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
IT95MI001587A 1995-07-21 1995-07-21 Epimeri del (22rs)-n-(1,1,1-trifluoro-2-fenilprop-2-il)-3-osso -4-aza-5alfa-androst-1-ene-17beta-carbossammide IT1275594B1 (it)

Priority Applications (17)

Application Number Priority Date Filing Date Title
IT95MI001587A IT1275594B1 (it) 1995-07-21 1995-07-21 Epimeri del (22rs)-n-(1,1,1-trifluoro-2-fenilprop-2-il)-3-osso -4-aza-5alfa-androst-1-ene-17beta-carbossammide
CA002199273A CA2199273A1 (en) 1995-07-21 1996-06-28 Epimers of (22rs)-n-(1,1,1-trifluoro-2-phenylprop-2-yl)-3-oxo-4-aza-5.alpha.-androst-1-ene-17.beta.-carboxamide
KR1019970701797A KR970706298A (ko) 1995-07-21 1996-06-28 (22RS)-N-(1,1,1-트리플루오로-2-페닐프로프-2-일)-3-옥소-4-아자-5α-안드로스트-1-엔-17β-카복스아미드의 에피머(Epimers of(22RS)-N-(1,1,1,-Trifluoro-2-phenylprop-2-yl)-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide)
PL96319351A PL319351A1 (en) 1995-07-21 1996-06-28 Epimers of (22rs)-n-(1,1,1-trifluoro-2-phenyprop-2-y)-3-oxo-4-aza-5a-androst-1-ene-17b carboxylamide
MX9701948A MX9701948A (es) 1995-07-21 1996-06-28 Epimeros de (22rs-n-(1,1,1-trifluoro-2-fenilprop-2-il)-3-oxo-4-aza-5alfa-androst-1-e n-17beta-carboxamida.
IL12034396A IL120343A0 (en) 1995-07-21 1996-06-28 Epimers of (22RS)-N-(1,1,1-trifluoro-2-phenylprop-2-YL)-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide
EP96923968A EP0782582A1 (en) 1995-07-21 1996-06-28 EPIMERS OF (22RS)-N-(1,1,1-TRIFLUORO-2-PHENYLPROP-2-YL)-3-OXO-4-AZA-5$g(a)-ANDROST-1-ENE-17$g(b)-CARBOXAMIDE
JP9506217A JPH10506411A (ja) 1995-07-21 1996-06-28 （２２ＲＳ）−Ｎ−（１，１，１−トリフルオロ−２−フェニルプロプ−２−イル）−３−オキソ−４−アザ−５α−アンドロスト−１−エン−１７β−カルボキサミド
AU64183/96A AU6418396A (en) 1995-07-21 1996-06-28 Epimers of (22RS)-N-(1,1,1-trifluoro-2-phenylprop-2-yl)-3-ox-4-aza-5alp ha-androst-1-ene-17beta-carboxamide
HU9702465A HUP9702465A3 (en) 1995-07-21 1996-06-28 Epimers of (22rs)-n-(1,1,1,-trifluoro-2-phenylprop-2-yl)-3-oxo-4-aza-5alfa-androst-1-ene-17beta-carboxamide, process for producing them and pharmaceutical compositions containing the same
PCT/EP1996/002830 WO1997004002A1 (en) 1995-07-21 1996-06-28 EPIMERS OF (22RS)-N-(1,1,1-TRIFLUORO-2-PHENYLPROP-2-YL)-3-OXO-4-AZA-5α-ANDROST-1-ENE-17β-CARBOXAMIDE
CN96190785A CN1159195A (zh) 1995-07-21 1996-06-28 (22RS)-N-(1，1，1-三氟-2-苯基丙-2-基)-3-氧代-4-氮杂-5α-雄甾-1-烯-17β-羧酰胺的差向异构体
BR9606527A BR9606527A (pt) 1995-07-21 1996-06-28 Epímeros processo para a preparação de um epimero composição farmacêutica que compreende um epímero e composto
ZA965678A ZA965678B (en) 1995-07-21 1996-07-04 Epimers of (22rs)-n-(1,1,1-trifluoro-2-phenylprop-2-yl)-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide
ARP960103652A AR003967A1 (es) 1995-07-21 1996-07-19 Epimeros de (22r)-n-(1,1,1-trifluoro-2-fenilprop-2-il)-3-oxo-4-aza-5alfa- androst-1-eno-17beta-carboxamida, un proceso para su preparacion y unacomposicion farmaceutica que los comprenden.
NO971196A NO971196L (no) 1995-07-21 1997-03-14 Epimerer av (22RS)-N-(1,1,1-trifluor-2-fenylprop-2-yl)-3-okso-4-aza-5<alfa>-androst-1-en-17<beta>-karboksamid
EA199700045A EA199700045A1 (ru) 1995-07-21 1997-04-18 ЭПИМЕРЫ (22RS)-N-(1,1,1-ТРИФТОР-2-ФЕНИЛПРОП-2-ИЛ)-3-ОКСО-4-АЗА-5α-АНДРОСТ-1-ЕН-17β-КАРБОКСАМИДА

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT95MI001587A IT1275594B1 (it) 1995-07-21 1995-07-21 Epimeri del (22rs)-n-(1,1,1-trifluoro-2-fenilprop-2-il)-3-osso -4-aza-5alfa-androst-1-ene-17beta-carbossammide

Publications (3)

Publication Number Publication Date
ITMI951587A0 true ITMI951587A0 (it) 1995-07-21
ITMI951587A1 ITMI951587A1 (it) 1997-01-21
IT1275594B1 IT1275594B1 (it) 1997-08-06

Family

ID=11372032

Family Applications (1)

Application Number Title Priority Date Filing Date
IT95MI001587A IT1275594B1 (it) 1995-07-21 1995-07-21 Epimeri del (22rs)-n-(1,1,1-trifluoro-2-fenilprop-2-il)-3-osso -4-aza-5alfa-androst-1-ene-17beta-carbossammide

Country Status (17)

Country Link
EP (1) EP0782582A1 (it)
JP (1) JPH10506411A (it)
KR (1) KR970706298A (it)
CN (1) CN1159195A (it)
AR (1) AR003967A1 (it)
AU (1) AU6418396A (it)
BR (1) BR9606527A (it)
CA (1) CA2199273A1 (it)
EA (1) EA199700045A1 (it)
HU (1) HUP9702465A3 (it)
IL (1) IL120343A0 (it)
IT (1) IT1275594B1 (it)
MX (1) MX9701948A (it)
NO (1) NO971196L (it)
PL (1) PL319351A1 (it)
WO (1) WO1997004002A1 (it)
ZA (1) ZA965678B (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6137399A (en) * 1998-09-09 2000-03-27 Merck & Co., Inc. Method of determining and reducing the risk of bph-related urologic events
DE60018707T2 (de) * 1999-01-25 2006-02-09 Smithkline Beecham Corp. Anti-androgene und verfahren zur behandlung von krankheiten
CN100355772C (zh) * 2005-12-28 2007-12-19 天津大学 具有5α－还原酶抑制活性的甾体化合物及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9216284D0 (en) * 1992-07-31 1992-09-16 Erba Carlo Spa Fluorinated 17beta-substituted 4-aza-5alpha-androstane-3-one derivatives

Also Published As

Publication number Publication date
NO971196D0 (no) 1997-03-14
AU6418396A (en) 1997-02-18
CA2199273A1 (en) 1997-02-06
PL319351A1 (en) 1997-08-04
WO1997004002A1 (en) 1997-02-06
ITMI951587A1 (it) 1997-01-21
HUP9702465A3 (en) 1998-11-30
NO971196L (no) 1997-03-14
HUP9702465A2 (hu) 1998-05-28
AR003967A1 (es) 1998-09-30
EA199700045A1 (ru) 1997-12-30
BR9606527A (pt) 1997-12-23
EP0782582A1 (en) 1997-07-09
MX9701948A (es) 1997-06-28
JPH10506411A (ja) 1998-06-23
CN1159195A (zh) 1997-09-10
IT1275594B1 (it) 1997-08-06
KR970706298A (ko) 1997-11-03
ZA965678B (en) 1997-01-24
IL120343A0 (en) 1997-06-10

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Legal Events

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