PL319351A1 - Epimers of (22rs)-n-(1,1,1-trifluoro-2-phenyprop-2-y)-3-oxo-4-aza-5a-androst-1-ene-17b carboxylamide - Google Patents

Epimers of (22rs)-n-(1,1,1-trifluoro-2-phenyprop-2-y)-3-oxo-4-aza-5a-androst-1-ene-17b carboxylamide

Info

Publication number
PL319351A1
PL319351A1 PL96319351A PL31935196A PL319351A1 PL 319351 A1 PL319351 A1 PL 319351A1 PL 96319351 A PL96319351 A PL 96319351A PL 31935196 A PL31935196 A PL 31935196A PL 319351 A1 PL319351 A1 PL 319351A1
Authority
PL
Poland
Prior art keywords
phenyprop
carboxylamide
androst
epimers
aza
Prior art date
Application number
PL96319351A
Other languages
English (en)
Inventor
Achille Panzeri
Marcella Nesi
Salle Enrico Di
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Publication of PL319351A1 publication Critical patent/PL319351A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL96319351A 1995-07-21 1996-06-28 Epimers of (22rs)-n-(1,1,1-trifluoro-2-phenyprop-2-y)-3-oxo-4-aza-5a-androst-1-ene-17b carboxylamide PL319351A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT95MI001587A IT1275594B1 (it) 1995-07-21 1995-07-21 Epimeri del (22rs)-n-(1,1,1-trifluoro-2-fenilprop-2-il)-3-osso -4-aza-5alfa-androst-1-ene-17beta-carbossammide
PCT/EP1996/002830 WO1997004002A1 (en) 1995-07-21 1996-06-28 EPIMERS OF (22RS)-N-(1,1,1-TRIFLUORO-2-PHENYLPROP-2-YL)-3-OXO-4-AZA-5α-ANDROST-1-ENE-17β-CARBOXAMIDE

Publications (1)

Publication Number Publication Date
PL319351A1 true PL319351A1 (en) 1997-08-04

Family

ID=11372032

Family Applications (1)

Application Number Title Priority Date Filing Date
PL96319351A PL319351A1 (en) 1995-07-21 1996-06-28 Epimers of (22rs)-n-(1,1,1-trifluoro-2-phenyprop-2-y)-3-oxo-4-aza-5a-androst-1-ene-17b carboxylamide

Country Status (17)

Country Link
EP (1) EP0782582A1 (it)
JP (1) JPH10506411A (it)
KR (1) KR970706298A (it)
CN (1) CN1159195A (it)
AR (1) AR003967A1 (it)
AU (1) AU6418396A (it)
BR (1) BR9606527A (it)
CA (1) CA2199273A1 (it)
EA (1) EA199700045A1 (it)
HU (1) HUP9702465A3 (it)
IL (1) IL120343A0 (it)
IT (1) IT1275594B1 (it)
MX (1) MX9701948A (it)
NO (1) NO971196D0 (it)
PL (1) PL319351A1 (it)
WO (1) WO1997004002A1 (it)
ZA (1) ZA965678B (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6137399A (en) * 1998-09-09 2000-03-27 Merck & Co., Inc. Method of determining and reducing the risk of bph-related urologic events
ES2237408T3 (es) * 1999-01-25 2005-08-01 Smithkline Beecham Corporation Antiandrogenos y procedimientos para tratar una enfermedad.
CN100355772C (zh) * 2005-12-28 2007-12-19 天津大学 具有5α－还原酶抑制活性的甾体化合物及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9216284D0 (en) * 1992-07-31 1992-09-16 Erba Carlo Spa Fluorinated 17beta-substituted 4-aza-5alpha-androstane-3-one derivatives

Also Published As

Publication number Publication date
ITMI951587A0 (it) 1995-07-21
HUP9702465A2 (hu) 1998-05-28
IL120343A0 (en) 1997-06-10
AU6418396A (en) 1997-02-18
AR003967A1 (es) 1998-09-30
BR9606527A (pt) 1997-12-23
EA199700045A1 (ru) 1997-12-30
NO971196L (no) 1997-03-14
CN1159195A (zh) 1997-09-10
CA2199273A1 (en) 1997-02-06
MX9701948A (es) 1997-06-28
EP0782582A1 (en) 1997-07-09
IT1275594B1 (it) 1997-08-06
ITMI951587A1 (it) 1997-01-21
WO1997004002A1 (en) 1997-02-06
KR970706298A (ko) 1997-11-03
ZA965678B (en) 1997-01-24
JPH10506411A (ja) 1998-06-23
NO971196D0 (no) 1997-03-14
HUP9702465A3 (en) 1998-11-30

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