ATE221883T1 - Substituierte 4-(1h-benzimidazol-2-yl)(1, 4)diazepane für die behandlung von allergischen krankheiten - Google Patents
Substituierte 4-(1h-benzimidazol-2-yl)(1, 4)diazepane für die behandlung von allergischen krankheitenInfo
- Publication number
- ATE221883T1 ATE221883T1 AT96944267T AT96944267T ATE221883T1 AT E221883 T1 ATE221883 T1 AT E221883T1 AT 96944267 T AT96944267 T AT 96944267T AT 96944267 T AT96944267 T AT 96944267T AT E221883 T1 ATE221883 T1 AT E221883T1
- Authority
- AT
- Austria
- Prior art keywords
- diazepans
- benzimidazole
- substituted
- treatment
- allergy diseases
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58000495A | 1995-12-20 | 1995-12-20 | |
| US73641196A | 1996-10-24 | 1996-10-24 | |
| PCT/US1996/019524 WO1997022604A1 (en) | 1995-12-20 | 1996-12-04 | Novel substituted 4-(1h-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE221883T1 true ATE221883T1 (de) | 2002-08-15 |
Family
ID=27077922
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96944267T ATE221883T1 (de) | 1995-12-20 | 1996-12-04 | Substituierte 4-(1h-benzimidazol-2-yl)(1, 4)diazepane für die behandlung von allergischen krankheiten |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0874843B1 (de) |
| JP (1) | JP2000500772A (de) |
| KR (1) | KR20000064487A (de) |
| CN (1) | CN1080262C (de) |
| AR (1) | AR005120A1 (de) |
| AT (1) | ATE221883T1 (de) |
| AU (1) | AU707914B2 (de) |
| BR (1) | BR9612074A (de) |
| CA (1) | CA2241827C (de) |
| DE (1) | DE69622889T2 (de) |
| DK (1) | DK0874843T3 (de) |
| ES (1) | ES2177827T3 (de) |
| HK (1) | HK1017684A1 (de) |
| IL (1) | IL125002A0 (de) |
| MX (1) | MX9804991A (de) |
| NO (1) | NO316932B1 (de) |
| NZ (1) | NZ325581A (de) |
| PT (1) | PT874843E (de) |
| TW (1) | TW335395B (de) |
| WO (1) | WO1997022604A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6194406B1 (en) * | 1995-12-20 | 2001-02-27 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease |
| US6423704B2 (en) | 1995-12-20 | 2002-07-23 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases |
| US6552188B2 (en) * | 2001-06-29 | 2003-04-22 | Kowa Co., Ltd. | Unsymmetrical cyclic diamine compound |
| EP1747198B1 (de) | 2004-05-07 | 2008-06-04 | Janssen Pharmaceutica N.V. | Adamantyl pyrrolidin-2-on-derivate als 11-beta hydroxysteroid dehydrogenas inhibitoren |
| NZ551077A (en) | 2004-05-07 | 2009-05-31 | Janssen Pharmaceutica Nv | Pyrrolidin-2-one and piperidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors |
| KR101197672B1 (ko) | 2004-08-30 | 2012-11-07 | 얀센 파마슈티카 엔.브이. | 11-베타 하이드록시스테로이드 데하이드로게나제저해제로서 트리사이클릭 락탐 유도체 |
| DE602005017159D1 (de) | 2004-08-30 | 2009-11-26 | Janssen Pharmaceutica Nv | Oxysteroid-dehydrogenase-inhibitoren |
| MY146435A (en) | 2004-08-30 | 2012-08-15 | Janssen Pharmaceutica Nv | N-2 adamantanyl-2-phenoxy-acetamide derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors |
| US20100105688A1 (en) | 2007-01-24 | 2010-04-29 | Glaxo Group Limited | Pharmaceutical compositions comprising 3,5-diamino-6-(2,3-dichlophenyl)-1,2,4-triazine or r(-)-2,4-diamino-5-(2,3-dichlorophenyl)-6-fluoromethyl pyrimidine and an nk1 |
| CN105646306B (zh) * | 2015-12-11 | 2020-06-30 | 广东莱佛士制药技术有限公司 | 一种4-甲硫基苯乙酸的制备方法 |
| EP3886854A4 (de) | 2018-11-30 | 2022-07-06 | Nuvation Bio Inc. | Pyrrol- und pyrazolverbindungen und verfahren zu deren verwendung |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2676055B1 (fr) * | 1991-05-03 | 1993-09-03 | Sanofi Elf | Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| FR2676054B1 (fr) * | 1991-05-03 | 1993-09-03 | Sanofi Elf | Nouveaux composes n-alkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| ATE158580T1 (de) * | 1993-05-06 | 1997-10-15 | Merrell Pharma Inc | Substituierte pyrrolidin-3-alkyl-piperidine verwendbar als tachykinin-antagonisten |
| KR960702445A (ko) * | 1993-05-20 | 1996-04-27 | 간자와 무츠오 | 1-(2-벤조이미다졸일)-1, 5- 디아자시클로옥탄 유도체(1-(2-benzimidazo-lyl)-1,5-diazacyclooctane compounds) |
| WO1996006094A1 (en) * | 1994-08-25 | 1996-02-29 | Merrell Pharmaceuticals Inc. | Novel substituted piperidines useful for the treatment of allergic diseases |
-
1996
- 1996-12-04 ES ES96944267T patent/ES2177827T3/es not_active Expired - Lifetime
- 1996-12-04 JP JP9522863A patent/JP2000500772A/ja active Pending
- 1996-12-04 BR BR9612074A patent/BR9612074A/pt unknown
- 1996-12-04 CA CA002241827A patent/CA2241827C/en not_active Expired - Fee Related
- 1996-12-04 WO PCT/US1996/019524 patent/WO1997022604A1/en not_active Application Discontinuation
- 1996-12-04 IL IL12500296A patent/IL125002A0/xx unknown
- 1996-12-04 DK DK96944267T patent/DK0874843T3/da active
- 1996-12-04 CN CN96199141A patent/CN1080262C/zh not_active Expired - Fee Related
- 1996-12-04 AU AU14119/97A patent/AU707914B2/en not_active Ceased
- 1996-12-04 EP EP96944267A patent/EP0874843B1/de not_active Expired - Lifetime
- 1996-12-04 NZ NZ325581A patent/NZ325581A/xx unknown
- 1996-12-04 AT AT96944267T patent/ATE221883T1/de not_active IP Right Cessation
- 1996-12-04 DE DE69622889T patent/DE69622889T2/de not_active Expired - Fee Related
- 1996-12-04 KR KR1019980704684A patent/KR20000064487A/ko active IP Right Grant
- 1996-12-04 PT PT96944267T patent/PT874843E/pt unknown
- 1996-12-18 AR ARP960105741A patent/AR005120A1/es active IP Right Grant
- 1996-12-21 TW TW085115838A patent/TW335395B/zh active
-
1998
- 1998-06-19 NO NO19982867A patent/NO316932B1/no not_active IP Right Cessation
- 1998-06-19 MX MX9804991A patent/MX9804991A/es not_active IP Right Cessation
-
1999
- 1999-07-05 HK HK99102816A patent/HK1017684A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NO316932B1 (no) | 2004-06-28 |
| DE69622889D1 (de) | 2002-09-12 |
| JP2000500772A (ja) | 2000-01-25 |
| AU1411997A (en) | 1997-07-14 |
| KR20000064487A (ko) | 2000-11-06 |
| NZ325581A (en) | 2000-03-27 |
| TW335395B (en) | 1998-07-01 |
| BR9612074A (pt) | 1999-03-30 |
| NO982867D0 (no) | 1998-06-19 |
| IL125002A0 (en) | 1999-01-26 |
| ES2177827T3 (es) | 2002-12-16 |
| MX9804991A (es) | 1998-09-30 |
| HK1017684A1 (en) | 1999-11-26 |
| WO1997022604A1 (en) | 1997-06-26 |
| NO982867L (no) | 1998-08-19 |
| DE69622889T2 (de) | 2003-04-10 |
| EP0874843B1 (de) | 2002-08-07 |
| CA2241827C (en) | 2002-04-30 |
| EP0874843A1 (de) | 1998-11-04 |
| AR005120A1 (es) | 1999-04-14 |
| CA2241827A1 (en) | 1997-06-26 |
| DK0874843T3 (da) | 2002-11-25 |
| PT874843E (pt) | 2002-12-31 |
| AU707914B2 (en) | 1999-07-22 |
| CN1207097A (zh) | 1999-02-03 |
| CN1080262C (zh) | 2002-03-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |