|
EP0903341A1
(en)
|
1997-07-22 |
1999-03-24 |
Akzo Nobel N.V. |
"Novel ortho-mercaptoaniline compounds"
|
|
CZ304734B6
(cs)
|
2000-07-21 |
2014-09-10 |
Gilead Sciences, Inc. |
Způsob přípravy 9-[2-(fosfonomethoxy)propyl]adeninu a 9-[2-(fosfonomethoxy)ethyl]adeninu
|
|
BRPI0408477A
(pt)
|
2003-03-10 |
2006-04-04 |
Pfizer |
compostos de éster de fosfato/sulfato e composições farmacêuticas para inibir a nima de interação com proteìna (pin 1) e uso dos mesmos
|
|
EP2359833A1
(en)
|
2003-04-25 |
2011-08-24 |
Gilead Sciences, Inc. |
Antiviral phosphonate analogs
|
|
ME03423B
(me)
|
2004-07-27 |
2020-01-20 |
Gilead Sciences Inc |
Fosfonatni analozi jedinjenja hiv inhibitora
|
|
TWI382019B
(zh)
|
2005-08-19 |
2013-01-11 |
Array Biopharma Inc |
作為類鐸受體(toll-like receptor)調節劑之胺基二氮雜呯
|
|
TWI404537B
(zh)
|
2005-08-19 |
2013-08-11 |
Array Biopharma Inc |
作為類鐸受體(toll-like receptor)調節劑之8-經取代苯并氮雜呯
|
|
CA2691444C
(en)
|
2007-06-29 |
2016-06-14 |
Gilead Sciences, Inc. |
Purine derivatives and their use as modulators of toll-like receptor 7
|
|
MX2010005334A
(es)
|
2007-11-16 |
2010-05-27 |
Boehringer Ingelheim Int |
Inhibidores de la replicacion del virus de la inmunodeficiencia humana.
|
|
PL2315756T3
(pl)
|
2008-07-08 |
2015-02-27 |
Incyte Holdings Corp |
1,2,5-oksadiazole jako inhibitory 2,3-dioksygenazy indoloaminy
|
|
WO2010014913A1
(en)
|
2008-08-01 |
2010-02-04 |
Ventirx Pharmaceuticals, Inc. |
Toll-like receptor agonist formulations and their use
|
|
ES2467108T3
(es)
|
2008-12-09 |
2014-06-11 |
Gilead Sciences, Inc. |
Moduladores de receptores tipo toll
|
|
EP2403860B1
(en)
*
|
2009-03-04 |
2015-11-04 |
IDENIX Pharmaceuticals, Inc. |
Phosphothiophene and phosphothiazole as hcv polymerase inhibitors
|
|
US8338441B2
(en)
|
2009-05-15 |
2012-12-25 |
Gilead Sciences, Inc. |
Inhibitors of human immunodeficiency virus replication
|
|
CA2771609C
(en)
|
2009-08-18 |
2018-10-02 |
Ventirx Pharmaceuticals, Inc. |
Substituted benzoazepines as toll-like receptor modulators
|
|
EP2467380B1
(en)
|
2009-08-18 |
2016-11-30 |
Ventirx Pharmaceuticals, Inc. |
Substituted benzoazepines as toll-like receptor modulators
|
|
US8962652B2
(en)
|
2009-10-22 |
2015-02-24 |
Gilead Sciences, Inc. |
Derivatives of purine or deazapurine useful for the treatment of (inter alia) viral infections
|
|
WO2011106573A2
(en)
|
2010-02-24 |
2011-09-01 |
Oryzon Genomics, S.A. |
Lysine demethylase inhibitors for diseases and disorders associated with hepadnaviridae
|
|
WO2011139637A1
(en)
|
2010-05-03 |
2011-11-10 |
Philadelphia Health & Education Corporation |
Small-molecule modulators of hiv-1 capsid stability and methods thereof
|
|
BR112012030711B1
(pt)
|
2010-05-31 |
2020-10-13 |
Ono Pharmaceutical Co. Ltd |
derivado de purinona
|
|
US20120149708A1
(en)
|
2010-06-17 |
2012-06-14 |
George Mason University |
Modulators of viral transcription, and methods and compositions therewith
|
|
KR20130124291A
(ko)
|
2010-07-02 |
2013-11-13 |
길리애드 사이언시즈, 인코포레이티드 |
Hiv 항바이러스 화합물로서의 2-퀴놀리닐-아세트산 유도체
|
|
AP2013006706A0
(en)
|
2010-07-02 |
2013-02-28 |
Gilead Sciences Inc |
Napht-2-ylacetic acid derivatives to treat AIDS
|
|
EP3485878A1
(en)
|
2010-09-01 |
2019-05-22 |
Arena Pharmaceuticals, Inc. |
Modified-release dosage forms of 5-ht2c agonists useful for weight management
|
|
US9102668B2
(en)
|
2010-09-08 |
2015-08-11 |
Glaxo Group Limited |
Polymorphs and salts
|
|
RS54286B1
(sr)
*
|
2010-09-08 |
2016-02-29 |
Glaxosmithkline Intellectual Property Development Limited |
Polimorfi i soli n-[5-[4-(5-{[(2r,6s)-2,6-dimetil-4-morfolinil]metil}-1,3-oksazol-2-il)-1h-indazol-6-il]-2(metiloksi)-3-piridinil]-metansulfonamida
|
|
US20120082658A1
(en)
|
2010-10-01 |
2012-04-05 |
Ventirx Pharmaceuticals, Inc. |
Methods for the Treatment of Allergic Diseases
|
|
JP5951615B2
(ja)
|
2010-10-01 |
2016-07-13 |
ベンティアールエックス ファーマシューティカルズ, インコーポレイテッドVentiRx Pharmaceuticals,Inc. |
Tlrアゴニストの治療用途および組み合わせ治療
|
|
UY33775A
(es)
|
2010-12-10 |
2012-07-31 |
Gilead Sciences Inc |
Inhibidores macrocíclicos de virus flaviviridae, composiciones farmacéuticas que los comprenden y sus usos
|
|
DK2663550T3
(en)
|
2011-01-12 |
2017-03-27 |
Ventirx Pharmaceuticals Inc |
SUBSTITUTED BENZOAZEPINS AS MODULATORS OF TOLL-LIKE RECEPTORS
|
|
CN103562201B
(zh)
|
2011-01-12 |
2016-10-19 |
帆德制药股份有限公司 |
作为toll样受体调节剂的取代的苯并氮杂卓
|
|
EA028659B1
(ru)
|
2011-02-12 |
2017-12-29 |
Глоубиммьюн, Инк. |
Терапевтическое средство на основе дрожжей для лечения хронического гепатита b
|
|
HUE055286T2
(hu)
|
2011-04-08 |
2021-11-29 |
Janssen Sciences Ireland Unlimited Co |
Pirimidinszármazékok vírusfertõzések kezelésére
|
|
BR112013027096A2
(pt)
|
2011-04-21 |
2016-12-27 |
Gilead Sciences Inc |
compostos de benzotiazol e seu uso farmacêutico
|
|
SG194852A1
(en)
|
2011-05-18 |
2013-12-30 |
Janssen R & D Ireland |
Quinazoline derivatives for the treatment of viral infections and further diseases
|
|
EP2729448B1
(en)
|
2011-07-06 |
2015-09-09 |
Gilead Sciences, Inc. |
Compounds for the treatment of hiv
|
|
CN102863512B
(zh)
|
2011-07-07 |
2016-04-20 |
上海泓博智源医药技术有限公司 |
抗病毒化合物
|
|
HRP20161696T4
(hr)
*
|
2011-08-16 |
2023-10-13 |
Gilead Sciences, Inc. |
Tenofovir alafenamid hemifumarat
|
|
DK2786996T3
(en)
|
2011-11-29 |
2016-12-19 |
Ono Pharmaceutical Co |
Hydrochloride PURINONDERIVAT
|
|
US9399645B2
(en)
|
2011-12-20 |
2016-07-26 |
Boehringer Ingelheim International Gmbh |
Inhibitors of HIV replication
|
|
WO2013096744A1
(en)
|
2011-12-21 |
2013-06-27 |
Novira Therapeutics, Inc. |
Hepatitis b antiviral agents
|
|
ES2874774T3
(es)
|
2011-12-22 |
2021-11-05 |
Geron Corp |
Análogos de guanina como sustratos de telomerasa y afectores de la longitud de los telómeros
|
|
DK2812331T3
(en)
|
2012-02-08 |
2019-04-08 |
Janssen Sciences Ireland Unlimited Co |
PIPERIDINOPYRIMIDINE DERIVATIVES FOR TREATING VIRUS INFECTIONS
|
|
US20130267517A1
(en)
|
2012-03-31 |
2013-10-10 |
Hoffmann-La Roche Inc. |
Novel 4-methyl-dihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
|
|
EP2831060B1
(en)
|
2012-03-31 |
2016-05-04 |
F.Hoffmann-La Roche Ag |
Novel 4-methyl-dihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
|
|
ES2571479T3
(es)
|
2012-04-20 |
2016-05-25 |
Gilead Sciences Inc |
Derivados del ácido benzotiazol-6-il acético y su uso para tratar una infección por VIH
|
|
PT2859009T
(pt)
|
2012-06-08 |
2018-01-18 |
Gilead Sciences Inc |
Inibidores macrocíclicos dos vírus flaviviridae
|
|
AR091279A1
(es)
|
2012-06-08 |
2015-01-21 |
Gilead Sciences Inc |
Inhibidores macrociclicos de virus flaviviridae
|
|
EA026235B1
(ru)
|
2012-06-08 |
2017-03-31 |
Джилид Сайэнс, Инк. |
Макроциклические ингибиторы вирусов flaviviridae
|
|
CN104781239B
(zh)
|
2012-08-10 |
2019-03-01 |
爱尔兰詹森科学公司 |
用于治疗病毒感染和另外的疾病的烷基嘧啶衍生物
|
|
EA038942B1
(ru)
|
2012-08-28 |
2021-11-12 |
Янссен Сайенсиз Айрлэнд Юси |
Сульфамоил-ариламиды и их применение в качестве лекарственных препаратов для лечения гепатита b
|
|
EA026957B1
(ru)
|
2012-08-28 |
2017-06-30 |
Янссен Сайенсиз Айрлэнд Юси |
Конденсированные бициклические производные сульфамоила и их применение в качестве лекарственных препаратов для лечения гепатита b
|
|
CN103665043B
(zh)
|
2012-08-30 |
2017-11-10 |
江苏豪森药业集团有限公司 |
一种替诺福韦前药及其在医药上的应用
|
|
MX2015002954A
(es)
|
2012-09-10 |
2015-06-05 |
Hoffmann La Roche |
Nuevas 6-aminoacido-heteroarilhidropirimidinas para el tratamiento y profilaxis de la infeccion del virus de la hepatitis b.
|
|
RS55764B1
(sr)
|
2012-10-02 |
2017-07-31 |
Gilead Sciences |
Inhibitori histonskih demetilaza
|
|
LT2906563T
(lt)
|
2012-10-10 |
2018-06-11 |
Janssen Sciences Ireland Uc |
Pirolo[3,2-d]pirimidino dariniai virusinių infekcijų ir kitų ligų gydymui
|
|
KR101268466B1
(ko)
|
2012-11-12 |
2013-06-04 |
유병수 |
사축형 윈드 터빈
|
|
EP2925729B1
(en)
|
2012-11-16 |
2017-10-18 |
Janssen Sciences Ireland UC |
Heterocyclic substituted 2-amino-quinazoline derivatives for the treatment of viral infections
|
|
EP2928471B1
(en)
|
2012-12-06 |
2020-10-14 |
Celgene Quanticel Research, Inc. |
Histone demethylase inhibitors
|
|
US8969343B2
(en)
|
2012-12-19 |
2015-03-03 |
Quanticel Pharmaceuticals, Inc. |
Histone demethylase inhibitors
|
|
EA030003B1
(ru)
|
2012-12-21 |
2018-06-29 |
Джилид Сайэнс, Инк. |
Полициклическое карбамоилпиридоновое соединение и его фармацевтическое применение для лечения вич-инфекции
|
|
WO2014100818A1
(en)
|
2012-12-21 |
2014-06-26 |
Quanticel Pharmaceuticals, Inc. |
Histone demethylase inhibitors
|
|
US20140221378A1
(en)
|
2012-12-27 |
2014-08-07 |
Japan Tobacco Inc. |
SUBSTITUTED SPIROPYRIDO[1,2-a]PYRAZINE DERIVATIVE AND PHARMACEUTICAL USE OF SAME AS HIV INTEGRASE INHIBITOR
|
|
WO2014128189A1
(en)
|
2013-02-21 |
2014-08-28 |
Janssen R&D Ireland |
2-aminopyrimidine derivatives for the treatment of viral infections
|
|
CA2901022C
(en)
|
2013-02-27 |
2021-05-04 |
Epitherapeutics Aps |
Substituted pyridine compounds as inhibitors of histone demethylases
|
|
HUE034820T2
(en)
|
2013-02-28 |
2018-02-28 |
Janssen Sciences Ireland Uc |
Sulphamoyl arylamides and their use as medicaments for the treatment of hepatitis B
|
|
JP6320506B2
(ja)
|
2013-03-12 |
2018-05-09 |
セルジーン クオンティセル リサーチ,インク. |
ヒストンデメチラーゼ阻害剤
|
|
US8993771B2
(en)
|
2013-03-12 |
2015-03-31 |
Novira Therapeutics, Inc. |
Hepatitis B antiviral agents
|
|
WO2014139326A1
(en)
|
2013-03-13 |
2014-09-18 |
Genentech, Inc. |
Pyrazolo compounds and uses thereof
|
|
ES2731773T3
(es)
|
2013-03-14 |
2019-11-19 |
Celgene Quanticel Res Inc |
Inhibidores de la histona desmetilasa
|
|
HRP20171609T1
(hr)
|
2013-03-15 |
2017-12-15 |
Quanticel Pharmaceuticals Inc |
Inhibitori histon demetilaze
|
|
EA027068B1
(ru)
|
2013-04-03 |
2017-06-30 |
Янссен Сайенсиз Айрлэнд Юси |
Производные n-фенилкарбоксамида и их применение в качестве лекарственных препаратов для лечения гепатита b
|
|
BR112015026252B1
(pt)
|
2013-04-15 |
2022-03-22 |
Becton, Dickinson And Company |
Dispositivo de coleta de fluido biológico e sistema de coleta e teste de fluido biológico
|
|
CN105209470B
(zh)
|
2013-05-17 |
2018-02-06 |
豪夫迈·罗氏有限公司 |
用于治疗和预防乙型肝炎病毒感染的6‑桥连的杂芳基二氢嘧啶
|
|
EA035500B1
(ru)
|
2013-05-17 |
2020-06-25 |
Янссен Сайенсиз Айрлэнд Юси |
Производные сульфамоилтиофенамида и их применение в качестве медикаментов для лечения гепатита b
|
|
TWI651300B
(zh)
|
2013-05-17 |
2019-02-21 |
健生科學愛爾蘭無限公司 |
胺磺醯基吡咯醯胺衍生物及其作為用於治療b型肝炎藥物的用途
|
|
CA2914381A1
(en)
|
2013-06-07 |
2014-12-11 |
Cipla Limited |
An efficient process for separation of diastereomers of 9-[(r)-2-[[(r,s)-[[(s)-1-(isopropoxycarbonyl)ethyl]amino]-phenoxyphosphinyl] methoxy]propyl]adenine
|
|
WO2015002434A1
(en)
|
2013-07-03 |
2015-01-08 |
Dong-A St Co.,Ltd |
Novel tenofovir disoproxil salt and the preparation method thereof
|
|
DK3024819T3
(en)
|
2013-07-25 |
2018-06-06 |
Janssen Sciences Ireland Uc |
GLYOXAMIDE-SUBSTITUTED PYRROLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICINES FOR TREATING HEPATITIS B
|
|
KR20150025993A
(ko)
|
2013-08-30 |
2015-03-11 |
동아에스티 주식회사 |
테노포비어 디소프록실 산부가염 및 이의 제조방법
|
|
DK3043865T3
(da)
|
2013-09-11 |
2021-02-01 |
Univ Claude Bernard Lyon |
Fremgangsmåder og farmaceutiske sammensætningr til behandlingen af hepatitis b-virusinfektion
|
|
WO2015040640A2
(en)
|
2013-09-20 |
2015-03-26 |
Laurus Labs Private Limited |
An improved process for the preparation of tenofovir alafenamide or pharmaceutically acceptable salts thereof
|
|
KR102290189B1
(ko)
|
2013-10-23 |
2021-08-17 |
얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 |
카르복스아미드 유도체 및 b형 간염 치료용 의약으로서의 이의 용도
|
|
AU2014348518B2
(en)
|
2013-11-14 |
2019-01-03 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
|
IN2014MU00118A
(https=)
*
|
2014-01-14 |
2015-08-28 |
Mylan Lab Ltd |
|
|
US9181288B2
(en)
|
2014-01-16 |
2015-11-10 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
|
US9169212B2
(en)
|
2014-01-16 |
2015-10-27 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
|
EA201691261A1
(ru)
|
2014-01-30 |
2016-11-30 |
Ф. Хоффманн-Ля Рош Аг |
Новые дигидрохинолизиноны для лечения и профилактики инфекции, вызванной вирусом гепатита b
|
|
WO2015118057A1
(en)
|
2014-02-06 |
2015-08-13 |
Janssen Sciences Ireland Uc |
Sulphamoylpyrrolamide derivatives and the use thereof as medicaments for the treatment of hepatitis b
|
|
JP6306750B2
(ja)
|
2014-03-07 |
2018-04-04 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
B型肝炎ウイルス感染症の治療および予防のための新規な6−縮合ヘテロアリールジヒドロピリミジン
|
|
US9400280B2
(en)
|
2014-03-27 |
2016-07-26 |
Novira Therapeutics, Inc. |
Piperidine derivatives and methods of treating hepatitis B infections
|
|
FR3020810B1
(fr)
*
|
2014-05-06 |
2016-05-06 |
Servier Lab |
Nouveau sel de l'ivabradine et son procede de preparation.
|
|
RU2016146365A
(ru)
|
2014-05-13 |
2018-06-19 |
Ф. Хоффманн-Ля Рош Аг |
Новые дигидрохинолизиноны для лечения и профилактики заражения вирусом гепатита b
|
|
CN105085571A
(zh)
*
|
2014-05-20 |
2015-11-25 |
四川海思科制药有限公司 |
替诺福韦艾拉酚胺复合物及其制备方法和用途
|
|
CN106535884A
(zh)
|
2014-06-06 |
2017-03-22 |
弗雷克萨斯生物科学公司 |
免疫调节剂
|
|
WO2016012470A1
(en)
|
2014-07-25 |
2016-01-28 |
F. Hoffmann-La Roche Ag |
New amorphous and crystalline forms of (3s)-4-[[(4r)-4-(2-chloro-4-fluoro-phenyl)-5-methoxycarbonyl-2-thiazol-2-yl-1, 4-dihydropyrimidin-6-yl]methyl]morpholine-3-carboxylic acid
|
|
JP6506836B2
(ja)
|
2014-08-14 |
2019-04-24 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
B型肝炎ウイルス感染症の処置および予防のための新規ピリダゾンおよびトリアジノン
|
|
SG11201701182VA
(en)
|
2014-08-27 |
2017-03-30 |
Gilead Sciences Inc |
Compounds and methods for inhibiting histone demethylases
|
|
EP3204379B1
(en)
|
2014-10-10 |
2019-03-06 |
Genentech, Inc. |
Pyrrolidine amide compounds as histone demethylase inhibitors
|
|
US9637485B2
(en)
|
2014-11-03 |
2017-05-02 |
Hoffmann-La Roche Inc. |
6,7-dihydrobenzo[a]quinolizin-2-one derivatives for the treatment and prophylaxis of hepatitis B virus infection
|
|
UY36390A
(es)
|
2014-11-05 |
2016-06-01 |
Flexus Biosciences Inc |
Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido), sus métodos de síntesis y composiciones farmacéuticas que los contienen
|
|
US20160144461A1
(en)
*
|
2014-11-21 |
2016-05-26 |
Huntington Alloys Corporation |
Ni-Cr-Mo-Ta-Nb Welding Filler Metals, Welding Filler Metal Consumables, Weld Deposits, Methods of Making Weld Deposits, and Weldments Thereof
|
|
CN104558036A
(zh)
|
2014-12-11 |
2015-04-29 |
杭州和泽医药科技有限公司 |
一种替诺福韦艾拉酚胺半反丁烯二酸盐晶型及其制备方法
|
|
AR103222A1
(es)
|
2014-12-23 |
2017-04-26 |
Hoffmann La Roche |
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|
|
US9676793B2
(en)
|
2014-12-23 |
2017-06-13 |
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Co-crystals of 5-amino-2-oxothiazolo[4,5-d]pyrimidin-3(2H)-yl-5-hydroxymethyl tetrahydrofuran-3-yl acetate and methods for preparing and using the same
|
|
WO2016107832A1
(en)
|
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2016-07-07 |
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Novel tetrahydropyridopyrimidines and tetrahydropyridopyridines for the treatment and prophylaxis of hepatitis b virus infection
|
|
EP3240913A1
(en)
|
2014-12-31 |
2017-11-08 |
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A novel high-throughput method for quantification of hbv cccdna from cell lysate by real-time pcr
|
|
MA41338B1
(fr)
|
2015-01-16 |
2019-07-31 |
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|
|
WO2016120186A1
(en)
|
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2016-08-04 |
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Recombinant hbv cccdna, the method to generate thereof and the use thereof
|
|
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(zh)
|
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2018-12-14 |
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|
|
CZ2015384A3
(cs)
|
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2016-12-14 |
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Pevné formy Tenofovir alafenamidu
|
|
EP4606784A3
(en)
*
|
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Co-crystals, salts and solid forms of tenofovir alafenamide
|
|
CA2921336A1
(en)
*
|
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Pharmaceutical formulations
|
|
TWI820984B
(zh)
|
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|