SI3515924T1 - Kristalinične oblike - Google Patents

Kristalinične oblike

Info

Publication number
SI3515924T1
SI3515924T1 SI201731102T SI201731102T SI3515924T1 SI 3515924 T1 SI3515924 T1 SI 3515924T1 SI 201731102 T SI201731102 T SI 201731102T SI 201731102 T SI201731102 T SI 201731102T SI 3515924 T1 SI3515924 T1 SI 3515924T1
Authority
SI
Slovenia
Prior art keywords
crystalline forms
crystalline
forms
Prior art date
Application number
SI201731102T
Other languages
English (en)
Inventor
Daniel Leuenberger
Stefan Reber
Raumer Markus Von
Original Assignee
Idorsia Pharmaceuticals Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idorsia Pharmaceuticals Ltd. filed Critical Idorsia Pharmaceuticals Ltd.
Publication of SI3515924T1 publication Critical patent/SI3515924T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SI201731102T 2016-09-22 2017-09-21 Kristalinične oblike SI3515924T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP2016072562 2016-09-22
EP17771436.7A EP3515924B1 (en) 2016-09-22 2017-09-21 Crystalline forms
PCT/EP2017/073858 WO2018055016A1 (en) 2016-09-22 2017-09-21 Crystalline forms

Publications (1)

Publication Number Publication Date
SI3515924T1 true SI3515924T1 (sl) 2022-04-29

Family

ID=59923448

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201731102T SI3515924T1 (sl) 2016-09-22 2017-09-21 Kristalinične oblike

Country Status (28)

Country Link
US (3) US10730896B2 (sl)
EP (2) EP3515924B1 (sl)
JP (1) JP7097369B2 (sl)
KR (1) KR102552795B1 (sl)
CN (1) CN109715639B (sl)
AU (1) AU2017331930B2 (sl)
BR (1) BR112019004845A2 (sl)
CA (1) CA3037794A1 (sl)
CL (1) CL2019000728A1 (sl)
CY (1) CY1125052T1 (sl)
DK (1) DK3515924T3 (sl)
EA (1) EA201990723A1 (sl)
ES (1) ES2908572T3 (sl)
HR (1) HRP20220234T1 (sl)
HU (1) HUE057772T2 (sl)
IL (1) IL265445B2 (sl)
LT (1) LT3515924T (sl)
MA (1) MA46266B1 (sl)
MX (1) MX2019003093A (sl)
MY (1) MY193080A (sl)
PH (1) PH12019500567A1 (sl)
PL (1) PL3515924T3 (sl)
PT (1) PT3515924T (sl)
RS (1) RS62946B1 (sl)
SI (1) SI3515924T1 (sl)
TW (1) TWI752086B (sl)
UA (1) UA124073C2 (sl)
WO (1) WO2018055016A1 (sl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018234056B2 (en) 2017-03-15 2023-05-25 Idorsia Pharmaceuticals Ltd Subcutaneous administration of a P2Y12 receptor antagonist
US20230255987A1 (en) 2020-07-15 2023-08-17 Idorsia Pharmaceuticals Ltd Aqueous pharmaceutical composition comprising a p2y12 receptor antagonist
WO2023285342A2 (en) 2021-07-13 2023-01-19 Idorsia Pharmaceuticals Ltd A process for the synthesis of 4-((r)-2-{[6-((s)-3-methoxy-pyrrolidin-1-yl)-2-phenyl- pyrimidine-4-carbonyl]-amino}-3-phosphono-propionyl)-piperazine-1 -carboxylic acid butyl ester

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5373586A (en) 1976-12-09 1978-06-30 Mitsubishi Chem Ind Ltd New penicillin derivatives
CA2020437A1 (en) 1989-07-05 1991-01-06 Yoshihide Fuse Cinnamamide derivative
DE60022508T2 (de) 1999-06-14 2006-06-08 Eli Lilly And Co., Indianapolis Inhibitoren von serin proteasen
US6861424B2 (en) 2001-06-06 2005-03-01 Schering Aktiengesellschaft Platelet adenosine diphosphate receptor antagonists
PL377053A1 (pl) 2002-12-11 2006-01-23 Schering Aktiengesellschaft Związki 2-aminokarbonylo-chinoliny jako antagonisty receptora płytkowego difosforanu adenozyny
BRPI0409255A (pt) 2003-04-09 2006-03-28 Wyeth Corp derivados de ácido 2-(8,9-dioxo-2,6-diazabi-ciclo(5.2.0)non-1(7)-en-2-il)alquil fosfÈnico e seu uso como antagonistas de receptores de d-asparto de -n-metila (nmda)
TW200640877A (en) 2005-04-28 2006-12-01 Actelion Pharmaceuticals Ltd Pyrimidine derivatives
AU2006305538B2 (en) 2005-10-21 2012-06-28 Idorsia Pharmaceuticals Ltd Piperazine derivatives as antimalarial agents
CL2007002920A1 (es) 2006-10-13 2008-06-06 Actelion Pharmaceuticals Ltd Compuestos derivados de 2-aminocarbonilpiridina; composicion farmaceutica; y uso para el tratamiento de trastornos vasculares oclusivos.
AR063518A1 (es) 2006-10-25 2009-01-28 Actelion Pharmaceuticals Ltd Derivados 2-fenil-6-aminocarbonil-pirimidina; composicion farmaceutica; y su uso para tratar y/o prevenir enfermedades vasculares perifericas viscerales, hepaticas y renales, enfermedades cardiovasculares y enfermedades cerebrovasculares asociados con la agregacion de plaquetas, incluyendo trombosis
JP4785881B2 (ja) 2007-02-27 2011-10-05 大塚製薬株式会社 医薬
KR20100015886A (ko) 2007-04-23 2010-02-12 사노피-아벤티스 P2y12 길항제로서의 퀴놀린-카복스아미드 유도체
CA2706475C (en) * 2007-11-29 2016-05-03 Actelion Pharmaceuticals Ltd Phosphonic acid derivates and their use as p2y12 receptor antagonists
WO2009080227A2 (en) 2007-12-26 2009-07-02 Sanofi-Aventis Pyrazole-carboxamide derivatives as p2y12 antagonists
WO2009080226A2 (en) 2007-12-26 2009-07-02 Sanofis-Aventis Heterocyclic pyrazole-carboxamides as p2y12 antagonists
AR071652A1 (es) 2008-04-11 2010-07-07 Actelion Pharmaceuticals Ltd Derivados 2- fenil-piridina substituidos
AR071653A1 (es) 2008-04-11 2010-07-07 Actelion Pharmaceuticals Ltd Derivados 2-fenil-4-ciclopropil-pirimidina
RU2011144763A (ru) 2009-04-08 2013-05-20 Актелион Фармасьютиклз Лтд 6-(3-азабицикло[3.1.0]гекс-3-ил)-2-фенилпиримидины
ES2469847T3 (es) 2009-04-22 2014-06-20 Actelion Pharmaceuticals Ltd. Derivados de tiazol y su uso como antagonistas del receptor P2Y12
AU2018234056B2 (en) 2017-03-15 2023-05-25 Idorsia Pharmaceuticals Ltd Subcutaneous administration of a P2Y12 receptor antagonist

Also Published As

Publication number Publication date
BR112019004845A2 (pt) 2019-06-04
KR102552795B1 (ko) 2023-07-06
US20200017534A1 (en) 2020-01-16
CN109715639A (zh) 2019-05-03
MA46266B1 (fr) 2022-02-28
KR20190052704A (ko) 2019-05-16
JP2019529553A (ja) 2019-10-17
HRP20220234T1 (hr) 2022-05-13
ES2908572T3 (es) 2022-05-03
PT3515924T (pt) 2022-03-11
TW201813965A (zh) 2018-04-16
NZ750772A (en) 2023-10-27
RS62946B1 (sr) 2022-03-31
EP3515924A1 (en) 2019-07-31
LT3515924T (lt) 2022-03-10
IL265445B2 (en) 2024-05-01
UA124073C2 (uk) 2021-07-14
US20210009614A1 (en) 2021-01-14
HUE057772T2 (hu) 2022-06-28
IL265445A (en) 2019-05-30
MY193080A (en) 2022-09-26
US20220275011A1 (en) 2022-09-01
AU2017331930B2 (en) 2021-07-15
US11365209B2 (en) 2022-06-21
US10730896B2 (en) 2020-08-04
IL265445B1 (en) 2024-01-01
EP3515924B1 (en) 2021-12-15
CY1125052T1 (el) 2024-02-16
TWI752086B (zh) 2022-01-11
CL2019000728A1 (es) 2019-07-05
AU2017331930A1 (en) 2019-03-07
WO2018055016A1 (en) 2018-03-29
PL3515924T3 (pl) 2022-04-11
MA46266A (fr) 2019-07-31
CN109715639B (zh) 2022-04-19
PH12019500567A1 (en) 2019-11-18
MX2019003093A (es) 2019-07-18
EA201990723A1 (ru) 2019-10-31
EP3981774A1 (en) 2022-04-13
JP7097369B2 (ja) 2022-07-07
DK3515924T3 (da) 2022-03-21
CA3037794A1 (en) 2018-03-29

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