PL2707380T3 - Dywersyfikacja oligosacharydów mleka kobiecego (hmo) lub ich prekursorów - Google Patents
Dywersyfikacja oligosacharydów mleka kobiecego (hmo) lub ich prekursorówInfo
- Publication number
- PL2707380T3 PL2707380T3 PL12785572T PL12785572T PL2707380T3 PL 2707380 T3 PL2707380 T3 PL 2707380T3 PL 12785572 T PL12785572 T PL 12785572T PL 12785572 T PL12785572 T PL 12785572T PL 2707380 T3 PL2707380 T3 PL 2707380T3
- Authority
- PL
- Poland
- Prior art keywords
- hmos
- diversification
- precursors
- human milk
- milk oligosaccharides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/12—Disaccharides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Dairy Products (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11166137 | 2011-05-13 | ||
| PCT/IB2012/051314 WO2012127410A1 (en) | 2011-03-18 | 2012-03-19 | Synthesis of new fucose-containing carbohydrate derivatives |
| PCT/IB2012/052401 WO2012156898A1 (en) | 2011-05-13 | 2012-05-14 | DIVERSIFICATION OF HUMAN MILK OLIGOSACCHARIDES (HMOs) OR PRECURSORS THEREOF |
| EP12785572.4A EP2707380B1 (en) | 2011-05-13 | 2012-05-14 | DIVERSIFICATION OF HUMAN MILK OLIGOSACCHARIDES (HMOs) OR PRECURSORS THEREOF |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2707380T3 true PL2707380T3 (pl) | 2021-01-11 |
Family
ID=47176364
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12785572T PL2707380T3 (pl) | 2011-05-13 | 2012-05-14 | Dywersyfikacja oligosacharydów mleka kobiecego (hmo) lub ich prekursorów |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US9382564B2 (pl) |
| EP (2) | EP3744725A1 (pl) |
| JP (1) | JP6106160B2 (pl) |
| KR (1) | KR20140036226A (pl) |
| CN (1) | CN103562214B9 (pl) |
| BR (1) | BR112013029203A2 (pl) |
| CA (1) | CA2835989A1 (pl) |
| DK (1) | DK2707380T3 (pl) |
| ES (1) | ES2820429T3 (pl) |
| IL (1) | IL229047A0 (pl) |
| MX (1) | MX349153B (pl) |
| PL (1) | PL2707380T3 (pl) |
| RU (1) | RU2013155453A (pl) |
| WO (1) | WO2012156898A1 (pl) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013531049A (ja) | 2010-07-16 | 2013-08-01 | グリコム アー／エス | オリゴ糖の誘導体化 |
| WO2013091660A1 (en) * | 2011-12-23 | 2013-06-27 | Glycom A/S | A method for obtaining crystalline lacto-n-tetraose and lacto-n-neotetraose precursors and mixtures thereof |
| EP2931737A4 (en) * | 2012-12-14 | 2016-11-16 | Glycom As | MIXTURE FROM FUCOSYLATE LACTOSES |
| BR112015025951A2 (pt) * | 2013-04-12 | 2017-10-17 | Univ Danmarks Tekniske | sialidase mutante com atividade trans-sialidase, para uso em produção de glicanos sialilados |
| GB201306689D0 (en) | 2013-04-12 | 2013-05-29 | Glycom As | Synthesis of sialylated/fucosylated human milk oligosaccharides |
| ES2891731T3 (es) | 2013-05-22 | 2022-01-31 | Glycom As | Mezcla sintética de oligosacáridos para el tratamiento de la microbiota de un mamífero |
| EP3041947A4 (en) | 2013-09-06 | 2017-07-26 | Glycom A/S | Fermentative production of oligosaccharides |
| EP2857410A1 (en) | 2013-10-04 | 2015-04-08 | Jennewein Biotechnologie GmbH | Process for purification of 2´-fucosyllactose using simulated moving bed chromatography |
| CN107108677B (zh) * | 2014-10-24 | 2020-08-07 | 格礼卡姆股份公司 | Hmo的混合物 |
| EP3209772A4 (en) | 2014-10-24 | 2018-08-08 | Glycom A/S | Mutated fucosidase |
| US11040049B2 (en) | 2014-10-29 | 2021-06-22 | Glycom A/S | Composition comprising HMSs/HMOs and use thereof |
| US11040050B2 (en) | 2014-10-29 | 2021-06-22 | Glycom A/S | Composition comprising HMSs/HMOs and use thereof |
| US20170258820A1 (en) | 2014-10-29 | 2017-09-14 | Glycom A/S | Synthetic composition and method for promoting mucosal healing |
| CN115364113A (zh) | 2014-10-29 | 2022-11-22 | 格礼卡姆股份公司 | 合成组合物以及用于治疗肠易激综合症的方法 |
| US10987368B2 (en) | 2014-12-08 | 2021-04-27 | Glycom A/S | Synthetic composition for preventing or treating CVD |
| CN115350200A (zh) | 2014-12-08 | 2022-11-18 | 格礼卡姆股份公司 | 用于治疗代谢障碍的合成组合物 |
| US10835544B2 (en) | 2014-12-08 | 2020-11-17 | Glycom A/S | Synthetic composition for regulating satiety |
| US10881674B2 (en) | 2014-12-08 | 2021-01-05 | Glycom A/S | Synthetic composition for treating metabolic disorders |
| EP3277287B8 (en) * | 2015-03-31 | 2023-12-27 | Glycom A/S | Mixtures of human milk oligosaccharides comprising 3 '-o-sialyllactose |
| ES2870973T3 (es) * | 2015-06-09 | 2021-10-28 | Glycom As | Mezclas ternarias de 6'-SL, LNnT y LST c |
| US10428318B2 (en) | 2015-06-09 | 2019-10-01 | Glycom A/S | Mutated sialidases |
| WO2017021476A1 (en) | 2015-08-04 | 2017-02-09 | Nestec S.A. | Nutritional compositions with 2fl and lnnt for use in inducing a gut microbiota close to the one of breast fed infants |
| PL3349763T3 (pl) | 2015-09-14 | 2022-01-03 | Glycom A/S | Kompozycja do zastosowania w modulowaniu mikrobioty |
| EP3368046B1 (en) | 2015-10-28 | 2022-07-27 | Glycom A/S | Synthetic composition and method for modulating brain function and behaviour |
| ES2950489T3 (es) | 2015-10-28 | 2023-10-10 | Glycom As | Composición sintética y método para modular los trastornos de la emoción y del ánimo |
| WO2017084673A1 (en) | 2015-11-17 | 2017-05-26 | Glycom A/S | Synthetic Composition for Treating Antibiotic Associated Complications |
| US11432578B2 (en) | 2015-12-15 | 2022-09-06 | Glycom A/S | Mixture of HMOs |
| WO2017144062A1 (en) | 2016-02-24 | 2017-08-31 | Glycom A/S | Synthetic composition for microbiota modulation |
| WO2017190754A1 (en) | 2016-05-05 | 2017-11-09 | Glycom A/S | Composition comprising hmos for the treatment of non-infectious diarrhoea |
| PL3452051T3 (pl) | 2016-05-05 | 2022-11-14 | Glycom A/S | Kompozycja zawierająca hmos do zastosowania w leczeniu nadwrażliwości trzewnej i/lub bólu trzewnego mediowanych komórkami tucznymi |
| US11224605B2 (en) | 2016-05-19 | 2022-01-18 | Glycom A/S | Synthetic composition |
| CN109414447A (zh) | 2016-06-24 | 2019-03-01 | 格礼卡姆股份公司 | 包括hmo的组合物、其制备和用于预防和/或治疗病毒和/或细菌感染的用途 |
| NZ750365A (en) | 2016-07-28 | 2022-07-01 | Fonterra Cooperative Group Ltd | Dairy product and process |
| WO2018157900A1 (en) | 2017-03-01 | 2018-09-07 | Glycom A/S | Synthetic composition for microbiota modulation |
| EP3634429A4 (en) | 2017-05-09 | 2020-11-04 | Glycom A/S | SYNTHETIC COMPOSITION FOR MICROBIOTE MODULATION |
| WO2018215960A1 (en) | 2017-05-24 | 2018-11-29 | Glycom A/S | Synthetic composition comprising one or more human milk oligosaccharides (hmos) |
| WO2018215961A1 (en) | 2017-05-24 | 2018-11-29 | Glycom A/S | Synthetic composition comprising oligosaccharides and its use in medical treatment. |
| US11142541B2 (en) | 2017-06-30 | 2021-10-12 | Glycom A/S | Purification of oligosaccharides |
| EP3672600A4 (en) | 2017-08-21 | 2021-05-19 | Glycom A/S | SYNTHETIC COMPOSITION TO REDUCE ALLERGY SYMPTOMS |
| EP3450443A1 (en) * | 2017-08-29 | 2019-03-06 | Jennewein Biotechnologie GmbH | Process for purifying sialylated oligosaccharides |
| CA3081496A1 (en) | 2017-11-02 | 2019-05-09 | Glycom A/S | Mixture of hmos for reducing or preventing fatigue |
| CN111698994A (zh) | 2017-11-30 | 2020-09-22 | 格礼卡姆股份公司 | 治疗小麦敏感性的hmo混合物 |
| US11602545B2 (en) | 2017-12-05 | 2023-03-14 | Glycom A/S | Human milk oligosaccharides for treating migraine |
| EP3722412A4 (en) * | 2017-12-08 | 2021-11-17 | Morinaga Milk Industry Co., Ltd. | NEW BIFIDOBACTERIUM, AND COMPOSITION CONTAINING THIS BACTERIA |
| US11304966B2 (en) | 2017-12-22 | 2022-04-19 | Glycom A/S | Composition comprising HMOs for preventing or reducing nociception |
| US11554131B2 (en) | 2018-05-31 | 2023-01-17 | Glycom A/S | Mixture of HMOs for treating autoimmune diseases |
| CN113194960A (zh) | 2018-12-19 | 2021-07-30 | 格礼卡姆股份公司 | 用于治疗使用低fodmap饮食的人的组合物和方法 |
| CN110016066B (zh) * | 2019-04-02 | 2021-11-02 | 江西师范大学 | 一种i型n-聚糖天线的合成方法 |
| CN114350640B (zh) * | 2019-12-13 | 2023-09-08 | 中国科学院天津工业生物技术研究所 | 一株表达几丁质酶重组菌的构建及高酶活突变体的筛选 |
| WO2022089707A1 (en) | 2020-10-30 | 2022-05-05 | Mille International Aps | A method of producing a human milk oligosaccharide (hmo) |
| CN112795583A (zh) * | 2020-11-16 | 2021-05-14 | 上海大学 | 重组唾液酸外切酶的制备方法、表达基因、重组表达载体及构建方法 |
| WO2022223430A1 (en) | 2021-04-19 | 2022-10-27 | Dsm Ip Assets B.V. | A composition of enzymes and human milk oligosaccharides |
| CN113960232B (zh) * | 2021-10-28 | 2024-02-20 | 苏州大学 | 一种基于唾液特异性岩藻糖基化结构糖谱及其检测方法和应用 |
| DK202200588A1 (en) | 2022-06-20 | 2024-02-23 | Dsm Ip Assets Bv | Mixture of fucosylated HMOs |
| WO2024042235A1 (en) | 2022-08-25 | 2024-02-29 | Dsm Ip Assets B.V. | Hybrid method for producing complex hmos |
| WO2024110667A1 (en) | 2022-11-25 | 2024-05-30 | Dsm Ip Assets B.V. | Two-strain system for producing oligosaccharides |
| DK202201151A1 (en) | 2022-12-14 | 2024-07-02 | Dsm Ip Assets B V | Mutated lacto-n-biosidase |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0586687A4 (en) * | 1992-03-25 | 1996-04-17 | Univ New York | Trans-sialidase and methods of use and making thereof |
| JPH0686684A (ja) | 1992-05-26 | 1994-03-29 | Monsanto Co | シアロ抱合体の合成 |
| US5409817A (en) | 1993-05-04 | 1995-04-25 | Cytel, Inc. | Use of trans-sialidase and sialyltransferase for synthesis of sialylα2→3βgalactosides |
| JPH11503328A (ja) * | 1995-04-11 | 1999-03-26 | サイテル コーポレイション | オリゴ糖類の改善された酵素合成法 |
| US6323008B1 (en) * | 1997-08-14 | 2001-11-27 | Neose Technologies, Inc. | Methods for producing sialyloligosaccharides in a dairy source |
| JP2005500058A (ja) * | 2001-08-17 | 2005-01-06 | ネオーズ テクノロジーズ， インコーポレイテッド | シアリル化したオリゴサッカリドの化学的酵素的合成 |
| JP5236189B2 (ja) * | 2003-12-05 | 2013-07-17 | チルドレンズ ホスピタル メディカル センター | オリゴ糖組成物および感染症の治療における該組成物の使用 |
| RU2442438C2 (ru) * | 2005-02-21 | 2012-02-20 | Нестек С.А. | Смесь олигосахаридов |
| JP4937288B2 (ja) | 2009-03-02 | 2012-05-23 | シャープ株式会社 | 画像読取装置及び画像形成装置 |
| DE202011111124U1 (de) * | 2010-02-19 | 2020-05-22 | Glycom A/S | Polymorph eines Tretrasaccharids, das N-Acetyllactosamin enthält |
| JP2013531049A (ja) | 2010-07-16 | 2013-08-01 | グリコム アー／エス | オリゴ糖の誘導体化 |
| EP2686330A4 (en) | 2011-03-18 | 2014-11-12 | Glycom As | SYNTHESIS OF NEW FUCOSE-CONTAINING CARBOHYDRATE DERIVATIVES |
-
2012
- 2012-05-14 CA CA2835989A patent/CA2835989A1/en not_active Abandoned
- 2012-05-14 DK DK12785572.4T patent/DK2707380T3/da active
- 2012-05-14 RU RU2013155453/04A patent/RU2013155453A/ru not_active Application Discontinuation
- 2012-05-14 WO PCT/IB2012/052401 patent/WO2012156898A1/en active Application Filing
- 2012-05-14 BR BR112013029203A patent/BR112013029203A2/pt not_active IP Right Cessation
- 2012-05-14 KR KR1020137032961A patent/KR20140036226A/ko not_active Application Discontinuation
- 2012-05-14 JP JP2014510920A patent/JP6106160B2/ja active Active
- 2012-05-14 US US14/117,332 patent/US9382564B2/en active Active
- 2012-05-14 PL PL12785572T patent/PL2707380T3/pl unknown
- 2012-05-14 EP EP20182361.4A patent/EP3744725A1/en active Pending
- 2012-05-14 EP EP12785572.4A patent/EP2707380B1/en active Active
- 2012-05-14 ES ES12785572T patent/ES2820429T3/es active Active
- 2012-05-14 MX MX2013013027A patent/MX349153B/es active IP Right Grant
- 2012-05-14 CN CN201280023818.4A patent/CN103562214B9/zh active Active
-
2013
- 2013-10-24 IL IL229047A patent/IL229047A0/en unknown
-
2016
- 2016-05-23 US US15/161,887 patent/US9963729B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| IL229047A0 (en) | 2013-12-31 |
| WO2012156898A1 (en) | 2012-11-22 |
| ES2820429T3 (es) | 2021-04-21 |
| MX349153B (es) | 2017-07-14 |
| BR112013029203A2 (pt) | 2016-08-09 |
| EP2707380B1 (en) | 2020-07-08 |
| RU2013155453A (ru) | 2015-06-20 |
| US20160289721A1 (en) | 2016-10-06 |
| CA2835989A1 (en) | 2012-11-22 |
| DK2707380T3 (da) | 2020-10-12 |
| EP3744725A1 (en) | 2020-12-02 |
| US9382564B2 (en) | 2016-07-05 |
| KR20140036226A (ko) | 2014-03-25 |
| CN103562214B (zh) | 2016-10-19 |
| MX2013013027A (es) | 2013-12-02 |
| EP2707380A1 (en) | 2014-03-19 |
| EP2707380A4 (en) | 2014-10-08 |
| JP6106160B2 (ja) | 2017-03-29 |
| CN103562214A (zh) | 2014-02-05 |
| JP2014513986A (ja) | 2014-06-19 |
| US20140212930A1 (en) | 2014-07-31 |
| US9963729B2 (en) | 2018-05-08 |
| CN103562214B9 (zh) | 2016-12-14 |
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