PL2073795T3 - Preparat leku zabezpieczony przed nadużywaniem - Google Patents
Preparat leku zabezpieczony przed nadużywaniemInfo
- Publication number
- PL2073795T3 PL2073795T3 PL07838274T PL07838274T PL2073795T3 PL 2073795 T3 PL2073795 T3 PL 2073795T3 PL 07838274 T PL07838274 T PL 07838274T PL 07838274 T PL07838274 T PL 07838274T PL 2073795 T3 PL2073795 T3 PL 2073795T3
- Authority
- PL
- Poland
- Prior art keywords
- drug formulation
- abuse resistant
- resistant drug
- abuse
- formulation
- Prior art date
Links
- 239000013583 drug formulation Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84512606P | 2006-09-15 | 2006-09-15 | |
| US84512806P | 2006-09-15 | 2006-09-15 | |
| US84512706P | 2006-09-15 | 2006-09-15 | |
| US84515106P | 2006-09-15 | 2006-09-15 | |
| US85045606P | 2006-10-10 | 2006-10-10 | |
| US11/900,851 US20080069891A1 (en) | 2006-09-15 | 2007-09-13 | Abuse resistant drug formulation |
| EP07838274.4A EP2073795B1 (en) | 2006-09-15 | 2007-09-14 | Abuse resistant drug formulation |
| PCT/US2007/020041 WO2008033523A1 (en) | 2006-09-15 | 2007-09-14 | Abuse resistant drug formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2073795T3 true PL2073795T3 (pl) | 2014-05-30 |
Family
ID=39035673
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL07838274T PL2073795T3 (pl) | 2006-09-15 | 2007-09-14 | Preparat leku zabezpieczony przed nadużywaniem |
| PL13190610T PL2692341T3 (pl) | 2006-09-15 | 2007-09-14 | Preparat leku zabezpieczony przed nadużywaniem |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13190610T PL2692341T3 (pl) | 2006-09-15 | 2007-09-14 | Preparat leku zabezpieczony przed nadużywaniem |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US20080069891A1 (enExample) |
| EP (2) | EP2692341B1 (enExample) |
| JP (1) | JP5357032B2 (enExample) |
| CA (1) | CA2663172C (enExample) |
| CY (1) | CY1115005T1 (enExample) |
| DK (2) | DK2073795T3 (enExample) |
| ES (2) | ES2543802T3 (enExample) |
| HU (1) | HUE027128T2 (enExample) |
| MX (1) | MX2009002757A (enExample) |
| PL (2) | PL2073795T3 (enExample) |
| PT (2) | PT2692341E (enExample) |
| SI (2) | SI2692341T1 (enExample) |
| WO (1) | WO2008033523A1 (enExample) |
Families Citing this family (99)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2295043A1 (en) | 1999-10-29 | 2011-03-16 | Euro-Celtique S.A. | Controlled release hydrocodone formulations |
| US10179130B2 (en) | 1999-10-29 | 2019-01-15 | Purdue Pharma L.P. | Controlled release hydrocodone formulations |
| EP2932964A1 (en) | 2000-10-30 | 2015-10-21 | Euro-Celtique S.A. | Controlled release hydrocodone formulations |
| US20030068375A1 (en) | 2001-08-06 | 2003-04-10 | Curtis Wright | Pharmaceutical formulation containing gelling agent |
| EP1429739A1 (en) | 2001-09-21 | 2004-06-23 | Egalet A/S | Polymer release system |
| WO2003024430A1 (en) | 2001-09-21 | 2003-03-27 | Egalet A/S | Morphine polymer release system |
| US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
| ES2570454T3 (es) | 2003-03-26 | 2016-05-18 | Egalet Ltd | Sistema de liberación controlada de morfina |
| DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
| DE102004032051A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
| DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
| US8075872B2 (en) | 2003-08-06 | 2011-12-13 | Gruenenthal Gmbh | Abuse-proofed dosage form |
| DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
| DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| US20080069891A1 (en) | 2006-09-15 | 2008-03-20 | Cima Labs, Inc. | Abuse resistant drug formulation |
| US8445018B2 (en) | 2006-09-15 | 2013-05-21 | Cima Labs Inc. | Abuse resistant drug formulation |
| AU2014200910B2 (en) * | 2006-10-03 | 2017-02-09 | Arbutus Biopharma Corporation | Lipid containing formulations |
| DE102007011485A1 (de) | 2007-03-07 | 2008-09-11 | Grünenthal GmbH | Darreichungsform mit erschwertem Missbrauch |
| EP2155167A2 (en) | 2007-06-04 | 2010-02-24 | Egalet A/S | Controlled release pharmaceutical compositions for prolonged effect |
| CN105534936B (zh) * | 2007-08-13 | 2020-07-31 | Ohemo 生命科学股份有限公司 | 抗滥用药物、使用方法和制备方法 |
| AU2009207796B2 (en) | 2008-01-25 | 2014-03-27 | Grunenthal Gmbh | Pharmaceutical dosage form |
| KR101690094B1 (ko) | 2008-05-09 | 2016-12-27 | 그뤼넨탈 게엠베하 | 분무 응결 단계의 사용하에 중간 분말 제형 및 최종 고체 제형을 제조하는 방법 |
| WO2010066034A1 (en) * | 2008-12-12 | 2010-06-17 | Paladin Labs Inc. | Methadone formulation |
| WO2010089132A1 (en) | 2009-02-06 | 2010-08-12 | Egalet A/S | Immediate release composition resistant to abuse by intake of alcohol |
| CA2766179A1 (en) | 2009-06-24 | 2010-12-29 | Egalet Ltd. | Controlled release formulations |
| CA2765971C (en) | 2009-07-22 | 2017-08-22 | Gruenenthal Gmbh | Hot-melt extruded controlled release dosage form |
| ES2428938T3 (es) | 2009-07-22 | 2013-11-12 | Grünenthal GmbH | Forma de dosificación resistente a la manipulación y estabilizada frente a la oxidación |
| CA2784407A1 (en) * | 2009-12-17 | 2011-07-14 | Cima Labs Inc. | Abuse-resistant formulations |
| US20110150989A1 (en) * | 2009-12-22 | 2011-06-23 | Mallinkckrodt Inc. | Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans |
| WO2011106416A2 (en) | 2010-02-24 | 2011-09-01 | Cima Labs Inc. | Abuse-resistant formulations |
| CA2798701A1 (en) * | 2010-05-11 | 2011-11-17 | Cima Labs Inc. | Alcohol-resistant extended release dosage forms comprising venlafaxine |
| US8927025B2 (en) | 2010-05-11 | 2015-01-06 | Cima Labs Inc. | Alcohol-resistant metoprolol-containing extended-release oral dosage forms |
| NZ603531A (en) * | 2010-05-11 | 2014-08-29 | Cima Labs Inc | Alcohol-resistant formulations |
| FR2959935B1 (fr) | 2010-05-14 | 2013-02-08 | Ethypharm Sa | Forme pharmaceutique orale alcoolo-resistante |
| PL2611425T3 (pl) | 2010-09-02 | 2014-09-30 | Gruenenthal Gmbh | Odporna na ingerencję postać dawki zawierająca polimer anionowy |
| RU2604676C2 (ru) | 2010-09-02 | 2016-12-10 | Грюненталь Гмбх | Устойчивая к разрушению лекарственная форма, содержащая неорганическую соль |
| HRP20171458T1 (hr) | 2011-07-29 | 2017-11-17 | Grünenthal GmbH | Tableta otporna na mijenjanje koja pruža neposredno oslobađanje lijeka |
| PL2736495T3 (pl) * | 2011-07-29 | 2018-01-31 | Gruenenthal Gmbh | Tabletka odporna na ingerencję, zapewniająca natychmiastowe uwalnianie leku |
| US20150224097A1 (en) * | 2011-11-22 | 2015-08-13 | Watson Pharmaceuticals, Inc. | Immediate Release Abuse Deterrent Tablet |
| DK2817000T3 (da) * | 2012-02-21 | 2021-10-11 | Towa Pharmaceutical Europe S L | Orale farmaceutiske sammensætninger af dabigatranetexilat |
| WO2013127831A1 (en) | 2012-02-28 | 2013-09-06 | Grünenthal GmbH | Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer |
| JP6004702B2 (ja) * | 2012-03-30 | 2016-10-12 | 小林製薬株式会社 | 不快味が軽減された固形製剤の製造方法 |
| US9993422B2 (en) | 2012-04-18 | 2018-06-12 | SpecGx LLC | Immediate release, abuse deterrent pharmaceutical compositions |
| MX2014011815A (es) * | 2012-04-18 | 2014-12-05 | Mallinckrodt Llc | Composiciones farmaceuticas de liberacion inmediata con propiedades disuasivas de abuso. |
| LT2838512T (lt) | 2012-04-18 | 2018-11-12 | Grünenthal GmbH | Pažeidimui atspari ir dozės atpalaidavimo nuokrypiui atspari farmacinė vaisto forma |
| US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
| CN104684548A (zh) | 2012-07-06 | 2015-06-03 | 埃格勒特有限责任公司 | 防止滥用的控释药物组合物 |
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| US10751287B2 (en) * | 2013-03-15 | 2020-08-25 | Purdue Pharma L.P. | Tamper resistant pharmaceutical formulations |
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| JP6445537B2 (ja) | 2013-05-29 | 2018-12-26 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 1個または複数の粒子を含有する改変防止(tamper−resistant)剤形 |
| AR096438A1 (es) | 2013-05-29 | 2015-12-30 | Gruenenthal Gmbh | Forma de dosificación resistente al uso indebido con perfil de liberación bimodal, proceso |
| US10624862B2 (en) | 2013-07-12 | 2020-04-21 | Grünenthal GmbH | Tamper-resistant dosage form containing ethylene-vinyl acetate polymer |
| JP6539274B2 (ja) | 2013-08-12 | 2019-07-03 | ファーマシューティカル マニュファクチュアリング リサーチ サービシズ,インコーポレーテッド | 押出成形された即放性乱用抑止性丸剤 |
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| TWI870622B (zh) * | 2020-10-02 | 2025-01-21 | 美商應用材料股份有限公司 | 製備氧化矽塗佈藥品的低溫處理 |
| CN112791046B (zh) * | 2021-01-22 | 2022-11-01 | 杭州汉达医药科技有限公司 | 一种具儿童安全保护功能的药物制剂和使用方法 |
| CN114366720B (zh) * | 2021-12-11 | 2023-07-21 | 江苏恩华药业股份有限公司 | 一种防滥用的三唑仑口服片剂及其制备方法 |
| WO2025057111A1 (en) | 2023-09-12 | 2025-03-20 | Clexio Biosciences Ltd. | Esketamine or a pharmaceutical salt thereof for use in a method of treating major depressive disorder |
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- 2007-09-14 PT PT131906109T patent/PT2692341E/pt unknown
- 2007-09-14 PL PL07838274T patent/PL2073795T3/pl unknown
- 2007-09-14 DK DK07838274.4T patent/DK2073795T3/da active
- 2007-09-14 DK DK13190610.9T patent/DK2692341T3/da active
- 2007-09-14 PL PL13190610T patent/PL2692341T3/pl unknown
- 2007-09-14 EP EP13190610.9A patent/EP2692341B1/en not_active Not-in-force
- 2007-09-14 ES ES13190610.9T patent/ES2543802T3/es active Active
- 2007-09-14 ES ES07838274.4T patent/ES2452033T3/es active Active
- 2007-09-14 HU HUE13190610A patent/HUE027128T2/en unknown
- 2007-09-14 JP JP2009528313A patent/JP5357032B2/ja not_active Expired - Fee Related
- 2007-09-14 WO PCT/US2007/020041 patent/WO2008033523A1/en not_active Ceased
- 2007-09-14 PT PT78382744T patent/PT2073795E/pt unknown
- 2007-09-14 EP EP07838274.4A patent/EP2073795B1/en not_active Not-in-force
- 2007-09-14 MX MX2009002757A patent/MX2009002757A/es active IP Right Grant
- 2007-09-14 SI SI200731669T patent/SI2692341T1/sl unknown
- 2007-09-14 SI SI200731408T patent/SI2073795T1/sl unknown
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2011
- 2011-04-27 US US13/095,434 patent/US20110200681A1/en not_active Abandoned
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2012
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-
2014
- 2014-03-07 CY CY20141100193T patent/CY1115005T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT2692341E (pt) | 2015-09-10 |
| EP2692341B1 (en) | 2015-05-27 |
| US20110200681A1 (en) | 2011-08-18 |
| CA2663172C (en) | 2014-12-23 |
| US20080069891A1 (en) | 2008-03-20 |
| PL2692341T3 (pl) | 2015-11-30 |
| JP5357032B2 (ja) | 2013-12-04 |
| ES2543802T3 (es) | 2015-08-24 |
| SI2073795T1 (sl) | 2014-03-31 |
| ES2452033T3 (es) | 2014-03-31 |
| JP2011504455A (ja) | 2011-02-10 |
| DK2692341T3 (da) | 2015-06-22 |
| CY1115005T1 (el) | 2016-12-14 |
| MX2009002757A (es) | 2009-06-10 |
| HUE027128T2 (en) | 2016-08-29 |
| US20130122087A1 (en) | 2013-05-16 |
| PT2073795E (pt) | 2014-02-27 |
| CA2663172A1 (en) | 2008-03-20 |
| DK2073795T3 (da) | 2014-02-03 |
| EP2073795B1 (en) | 2013-12-18 |
| HK1193567A1 (en) | 2014-09-26 |
| EP2692341A1 (en) | 2014-02-05 |
| EP2073795A1 (en) | 2009-07-01 |
| HK1134775A1 (en) | 2010-05-14 |
| US9974751B2 (en) | 2018-05-22 |
| SI2692341T1 (sl) | 2015-08-31 |
| WO2008033523A1 (en) | 2008-03-20 |
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