PL2073795T3 - Preparat leku zabezpieczony przed nadużywaniem - Google Patents
Preparat leku zabezpieczony przed nadużywaniemInfo
- Publication number
- PL2073795T3 PL2073795T3 PL07838274T PL07838274T PL2073795T3 PL 2073795 T3 PL2073795 T3 PL 2073795T3 PL 07838274 T PL07838274 T PL 07838274T PL 07838274 T PL07838274 T PL 07838274T PL 2073795 T3 PL2073795 T3 PL 2073795T3
- Authority
- PL
- Poland
- Prior art keywords
- drug formulation
- abuse resistant
- resistant drug
- abuse
- formulation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84515106P | 2006-09-15 | 2006-09-15 | |
| US84512806P | 2006-09-15 | 2006-09-15 | |
| US84512706P | 2006-09-15 | 2006-09-15 | |
| US84512606P | 2006-09-15 | 2006-09-15 | |
| US85045606P | 2006-10-10 | 2006-10-10 | |
| US11/900,851 US20080069891A1 (en) | 2006-09-15 | 2007-09-13 | Abuse resistant drug formulation |
| EP07838274.4A EP2073795B1 (en) | 2006-09-15 | 2007-09-14 | Abuse resistant drug formulation |
| PCT/US2007/020041 WO2008033523A1 (en) | 2006-09-15 | 2007-09-14 | Abuse resistant drug formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2073795T3 true PL2073795T3 (pl) | 2014-05-30 |
Family
ID=39035673
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13190610T PL2692341T3 (pl) | 2006-09-15 | 2007-09-14 | Preparat leku zabezpieczony przed nadużywaniem |
| PL07838274T PL2073795T3 (pl) | 2006-09-15 | 2007-09-14 | Preparat leku zabezpieczony przed nadużywaniem |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13190610T PL2692341T3 (pl) | 2006-09-15 | 2007-09-14 | Preparat leku zabezpieczony przed nadużywaniem |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US20080069891A1 (pl) |
| EP (2) | EP2692341B1 (pl) |
| JP (1) | JP5357032B2 (pl) |
| CA (1) | CA2663172C (pl) |
| CY (1) | CY1115005T1 (pl) |
| DK (2) | DK2073795T3 (pl) |
| ES (2) | ES2543802T3 (pl) |
| HK (2) | HK1134775A1 (pl) |
| HU (1) | HUE027128T2 (pl) |
| MX (1) | MX2009002757A (pl) |
| PL (2) | PL2692341T3 (pl) |
| PT (2) | PT2692341E (pl) |
| SI (2) | SI2692341T1 (pl) |
| WO (1) | WO2008033523A1 (pl) |
Families Citing this family (95)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10179130B2 (en) | 1999-10-29 | 2019-01-15 | Purdue Pharma L.P. | Controlled release hydrocodone formulations |
| KR101476574B1 (ko) | 1999-10-29 | 2014-12-24 | 유로-셀티크 소시에떼 아노뉨 | 서방성 하이드로코돈 제형 |
| MXPA03003895A (es) | 2000-10-30 | 2003-07-28 | Euro Celtique Sa | Formulaciones de hidrocodona de liberacion controlada. |
| US20030068375A1 (en) | 2001-08-06 | 2003-04-10 | Curtis Wright | Pharmaceutical formulation containing gelling agent |
| US20040234602A1 (en) | 2001-09-21 | 2004-11-25 | Gina Fischer | Polymer release system |
| WO2003024430A1 (en) | 2001-09-21 | 2003-03-27 | Egalet A/S | Morphine polymer release system |
| US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
| EP1610767B1 (en) | 2003-03-26 | 2011-01-19 | Egalet A/S | Morphine controlled release system |
| US8075872B2 (en) | 2003-08-06 | 2011-12-13 | Gruenenthal Gmbh | Abuse-proofed dosage form |
| DE102004032051A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
| DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
| DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
| DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
| DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| US20080069891A1 (en) | 2006-09-15 | 2008-03-20 | Cima Labs, Inc. | Abuse resistant drug formulation |
| US8445018B2 (en) | 2006-09-15 | 2013-05-21 | Cima Labs Inc. | Abuse resistant drug formulation |
| AU2014200910B2 (en) * | 2006-10-03 | 2017-02-09 | Arbutus Biopharma Corporation | Lipid containing formulations |
| DE102007011485A1 (de) | 2007-03-07 | 2008-09-11 | Grünenthal GmbH | Darreichungsform mit erschwertem Missbrauch |
| NZ580972A (en) | 2007-06-04 | 2012-02-24 | Egalet Ltd | Controlled release pharmaceutical compositions for prolonged effect |
| ES2692437T3 (es) * | 2007-08-13 | 2018-12-03 | Abuse Deterrent Pharmaceutical Llc | Fármacos resistentes al abuso, método de uso y método de preparación |
| TWI454288B (zh) | 2008-01-25 | 2014-10-01 | Gruenenthal Chemie | 藥物劑型 |
| SI2273983T1 (sl) | 2008-05-09 | 2016-11-30 | Gruenenthal Gmbh | Postopek za pripravo intermediatne praškaste formulacije in končne trdne odmerne oblike z uporabo stopnje strjevanja z razprševanjem |
| PL2379111T3 (pl) * | 2008-12-12 | 2013-08-30 | Paladin Labs Inc | Preparaty leków narkotycznych o obniżonym potencjale uzależniającym |
| CA2751667C (en) | 2009-02-06 | 2016-12-13 | Egalet Ltd. | Immediate release composition resistant to abuse by intake of alcohol |
| EP2445487A2 (en) | 2009-06-24 | 2012-05-02 | Egalet Ltd. | Controlled release formulations |
| JP5667183B2 (ja) | 2009-07-22 | 2015-02-12 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 加熱溶融押出成型した制御放出性投与剤型 |
| JP2012533585A (ja) | 2009-07-22 | 2012-12-27 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 酸化感受性オピオイドのための不正使用防止剤形 |
| CA2784407A1 (en) * | 2009-12-17 | 2011-07-14 | Cima Labs Inc. | Abuse-resistant formulations |
| US20110150989A1 (en) * | 2009-12-22 | 2011-06-23 | Mallinkckrodt Inc. | Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans |
| EP2538928B1 (en) | 2010-02-24 | 2017-05-03 | Cima Labs Inc. | Abuse-resistant formulations |
| US8927025B2 (en) | 2010-05-11 | 2015-01-06 | Cima Labs Inc. | Alcohol-resistant metoprolol-containing extended-release oral dosage forms |
| CA2798700C (en) * | 2010-05-11 | 2018-08-21 | Cima Labs Inc. | Alcohol-resistant formulations |
| US20130171256A1 (en) * | 2010-05-11 | 2013-07-04 | Cima Labs Inc. | Alcohol-resistant extended release dosage forms comprising venlafaxine |
| US20130059010A1 (en) | 2010-05-14 | 2013-03-07 | Ethypharm | Alcohol-resistant oral pharmaceutical form |
| US9636303B2 (en) | 2010-09-02 | 2017-05-02 | Gruenenthal Gmbh | Tamper resistant dosage form comprising an anionic polymer |
| ES2486791T3 (es) | 2010-09-02 | 2014-08-19 | Grünenthal GmbH | Forma de dosificación resistente a la manipulación que comprende una sal inorgánica |
| US20130028972A1 (en) * | 2011-07-29 | 2013-01-31 | Grunenthal Gmbh | Tamper-resistant tablet providing immediate drug release |
| AR087360A1 (es) | 2011-07-29 | 2014-03-19 | Gruenenthal Gmbh | Tableta a prueba de manipulacion que proporciona liberacion de farmaco inmediato |
| EP2782558A4 (en) * | 2011-11-22 | 2015-03-18 | Watson Pharmaceuticals Inc | MISSABLE TABLET WITH IMMEDIATE RELEASE |
| HRP20211606T1 (hr) * | 2012-02-21 | 2022-01-21 | Towa Pharmaceutical Europe, S.L. | Oralni farmaceutski pripravci dabigatran-eteksilata |
| BR112014019988A8 (pt) | 2012-02-28 | 2017-07-11 | Gruenenthal Gmbh | Forma de dosagem resistente a socamento compreendendo um composto farmacologicamente ativo e um polímero aniônico |
| JP6004702B2 (ja) * | 2012-03-30 | 2016-10-12 | 小林製薬株式会社 | 不快味が軽減された固形製剤の製造方法 |
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| JP6067100B2 (ja) | 2012-04-18 | 2017-01-25 | マリンクロッド エルエルシー | 即放性乱用抑止医薬組成物 |
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| CA2877183A1 (en) | 2012-07-06 | 2014-01-09 | Egalet Ltd. | Abuse deterrent pharmaceutical compositions for controlled release |
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| US10751287B2 (en) * | 2013-03-15 | 2020-08-25 | Purdue Pharma L.P. | Tamper resistant pharmaceutical formulations |
| US11571390B2 (en) | 2013-03-15 | 2023-02-07 | Othemo Life Sciences, Inc. | Abuse deterrent compositions and methods of use |
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| WO2015120201A1 (en) * | 2014-02-05 | 2015-08-13 | Kashiv Pharma, Llc | Abuse-resistant drug formulations with built-in overdose protection |
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| US10842750B2 (en) | 2015-09-10 | 2020-11-24 | Grünenthal GmbH | Protecting oral overdose with abuse deterrent immediate release formulations |
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| ES2963929T3 (es) | 2017-05-29 | 2024-04-03 | Gruenenthal Gmbh | Forma farmacéutica oral multipartículas que proporciona liberación prolongada de tapentadol |
| US10335375B2 (en) | 2017-05-30 | 2019-07-02 | Patheon Softgels, Inc. | Anti-overingestion abuse deterrent compositions |
| MX2021002459A (es) | 2018-09-25 | 2021-04-29 | SpecGx LLC | Formas de dosificacion en capsula disuasorias del abuso de liberacion inmediata. |
| JP2022504036A (ja) | 2018-10-05 | 2022-01-13 | クレキシオ バイオサイエンシーズ エルティーディー． | 大うつ病性障害を治療するためのエスケタミンの投与計画 |
| WO2020070547A1 (en) | 2018-10-05 | 2020-04-09 | Clexio Biosciences Ltd. | Dosage regime of esketamine for treating major depressive disorder |
| WO2020070706A1 (en) | 2018-10-05 | 2020-04-09 | Clexio Biosciences Ltd. | Dosage regime of esketamine for treating major depressive disorder |
| US20210378989A1 (en) | 2018-10-11 | 2021-12-09 | Clexio Biosciences Ltd. | Esketamine for use in treating major depressive disorder |
| EP3698776A1 (en) | 2019-02-19 | 2020-08-26 | Grünenthal GmbH | Tamper-resistant dosage form with immediate release and resistance against solvent extraction |
| GR1009751B (el) | 2019-03-22 | 2020-05-29 | "Φαρματεν Α.Β.Ε.Ε." | Σκευασμα παρατεταμενης αποδεσμευσης που περιλαμβανει οξαλικη ταπενταδολη και μεθοδος παρασκευης αυτου |
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- 2007-09-14 SI SI200731669T patent/SI2692341T1/sl unknown
- 2007-09-14 PL PL13190610T patent/PL2692341T3/pl unknown
- 2007-09-14 DK DK07838274.4T patent/DK2073795T3/da active
- 2007-09-14 PT PT131906109T patent/PT2692341E/pt unknown
- 2007-09-14 PL PL07838274T patent/PL2073795T3/pl unknown
- 2007-09-14 DK DK13190610.9T patent/DK2692341T3/da active
- 2007-09-14 WO PCT/US2007/020041 patent/WO2008033523A1/en active Application Filing
- 2007-09-14 SI SI200731408T patent/SI2073795T1/sl unknown
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- 2007-09-14 EP EP07838274.4A patent/EP2073795B1/en active Active
- 2007-09-14 JP JP2009528313A patent/JP5357032B2/ja not_active Expired - Fee Related
- 2007-09-14 PT PT78382744T patent/PT2073795E/pt unknown
- 2007-09-14 CA CA2663172A patent/CA2663172C/en not_active Expired - Fee Related
- 2007-09-14 HU HUE13190610A patent/HUE027128T2/en unknown
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2009
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Also Published As
| Publication number | Publication date |
|---|---|
| PL2692341T3 (pl) | 2015-11-30 |
| MX2009002757A (es) | 2009-06-10 |
| HK1134775A1 (en) | 2010-05-14 |
| JP2011504455A (ja) | 2011-02-10 |
| US20080069891A1 (en) | 2008-03-20 |
| DK2692341T3 (da) | 2015-06-22 |
| DK2073795T3 (da) | 2014-02-03 |
| EP2692341B1 (en) | 2015-05-27 |
| CY1115005T1 (el) | 2016-12-14 |
| US9974751B2 (en) | 2018-05-22 |
| EP2073795B1 (en) | 2013-12-18 |
| PT2692341E (pt) | 2015-09-10 |
| SI2073795T1 (sl) | 2014-03-31 |
| SI2692341T1 (sl) | 2015-08-31 |
| CA2663172C (en) | 2014-12-23 |
| HUE027128T2 (en) | 2016-08-29 |
| PT2073795E (pt) | 2014-02-27 |
| ES2543802T3 (es) | 2015-08-24 |
| EP2073795A1 (en) | 2009-07-01 |
| WO2008033523A1 (en) | 2008-03-20 |
| US20110200681A1 (en) | 2011-08-18 |
| JP5357032B2 (ja) | 2013-12-04 |
| ES2452033T3 (es) | 2014-03-31 |
| EP2692341A1 (en) | 2014-02-05 |
| CA2663172A1 (en) | 2008-03-20 |
| HK1193567A1 (en) | 2014-09-26 |
| US20130122087A1 (en) | 2013-05-16 |
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