PL2070526T3 - Sposoby leczenia choroby Parkinsona - Google Patents

Sposoby leczenia choroby Parkinsona

Info

Publication number
PL2070526T3
PL2070526T3 PL09154864T PL09154864T PL2070526T3 PL 2070526 T3 PL2070526 T3 PL 2070526T3 PL 09154864 T PL09154864 T PL 09154864T PL 09154864 T PL09154864 T PL 09154864T PL 2070526 T3 PL2070526 T3 PL 2070526T3
Authority
PL
Poland
Prior art keywords
parkinson
disease
treatment
methods
Prior art date
Application number
PL09154864T
Other languages
English (en)
Inventor
Fariello Ruggero
Carlo Cattaneo
Patricia Salvati
Luca Benatti
Original Assignee
Newron Pharm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33159845&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2070526(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Newron Pharm Spa filed Critical Newron Pharm Spa
Publication of PL2070526T3 publication Critical patent/PL2070526T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL09154864T 2003-04-11 2004-04-08 Sposoby leczenia choroby Parkinsona PL2070526T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46220503P 2003-04-11 2003-04-11
EP04726590A EP1613296B1 (en) 2003-04-11 2004-04-08 Methods for treatment of parkinson's disease
EP09154864.4A EP2070526B1 (en) 2003-04-11 2004-04-08 Methods for treatment of Parkinson's disease

Publications (1)

Publication Number Publication Date
PL2070526T3 true PL2070526T3 (pl) 2014-08-29

Family

ID=33159845

Family Applications (2)

Application Number Title Priority Date Filing Date
PL09154864T PL2070526T3 (pl) 2003-04-11 2004-04-08 Sposoby leczenia choroby Parkinsona
PL04726590T PL1613296T3 (pl) 2003-04-11 2004-04-08 Sposoby leczenia choroby Parkinsona

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL04726590T PL1613296T3 (pl) 2003-04-11 2004-04-08 Sposoby leczenia choroby Parkinsona

Country Status (28)

Country Link
US (3) US8283380B2 (pl)
EP (2) EP2070526B1 (pl)
JP (2) JP2006522800A (pl)
KR (2) KR20110070929A (pl)
CN (2) CN1771030A (pl)
AR (1) AR044007A1 (pl)
AT (1) ATE435012T1 (pl)
AU (1) AU2004228782B2 (pl)
BR (1) BRPI0409364A (pl)
CA (1) CA2523188C (pl)
CY (3) CY1109295T1 (pl)
DE (1) DE602004021790D1 (pl)
DK (2) DK2070526T3 (pl)
ES (2) ES2454272T3 (pl)
FR (1) FR15C0054I2 (pl)
HU (1) HUS1500043I1 (pl)
IL (2) IL171331A (pl)
LU (1) LU92782I2 (pl)
MX (1) MXPA05010873A (pl)
NL (1) NL300752I2 (pl)
NO (3) NO334316B1 (pl)
NZ (1) NZ542910A (pl)
PL (2) PL2070526T3 (pl)
PT (2) PT1613296E (pl)
RU (1) RU2342929C2 (pl)
SI (2) SI1613296T1 (pl)
TW (1) TWI340640B (pl)
WO (1) WO2004089353A2 (pl)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
AU2002333374B2 (en) 2001-09-03 2007-03-22 Newron Pharmaceuticals S.P.A. Pharmaceutical composition comprising gabapentin or an analogue thereof and an (alpha)- aminoamide and its analgesic use
EP1438956A1 (en) * 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
DE602004025586D1 (de) * 2003-08-25 2010-04-01 Newron Pharm Spa Alpha-aminoamid derivate zur verwendung als anti-inflammatorische wirkstoffe
EP1588704A1 (en) 2004-04-22 2005-10-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders
ATE471147T1 (de) * 2004-09-10 2010-07-15 Newron Pharm Spa Verwendung von (r)-(halogenbenzyloxy)-benzylamino-propanamiden als natrium- und/oder calciumkanal- selektive modulatoren
US20070004639A1 (en) * 2005-07-01 2007-01-04 Bodybio, Inc. Methods and compositions for treating Parkinson's disease
EP1954256A2 (en) 2005-11-09 2008-08-13 Torrent Pharmaceuticals Ltd Pharmaceutical composition comprising a compound having a catechol moiety and an alkalising agent
DK1963280T3 (en) * 2005-12-22 2015-12-14 Newron Pharm Spa 2-phenylethylamine derivatives by calcium and / or sodium channel
CN101032474B (zh) * 2006-03-06 2011-02-16 重庆医药工业研究院有限责任公司 一种治疗或预防神经系统疾病的雷沙吉兰透皮贴片及其制备方法
EP1870097A1 (en) * 2006-06-15 2007-12-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of cognitive disorders
US8106056B2 (en) * 2006-06-16 2012-01-31 Solvay Pharmaceuticals B.V. Combination preparations comprising bifeprunox and a dopamine agonist
WO2007147491A1 (en) * 2006-06-19 2007-12-27 Newron Pharmaceuticals S.P.A. Process for the production of 2- [4 - ( 3- and 2-flu0r0benzyl0xy) benzylamin0] propan amides
DE102007014947B4 (de) * 2007-03-23 2010-05-27 Axxonis Pharma Ag Stabilisierte wässrige Lösungen von Ergolinverbindungen
EP2150239A1 (en) * 2007-04-24 2010-02-10 Boehringer Ingelheim International GmbH Combination with an extended release tablet formulation containing pramipexole or a pharmaceutically acceptable salt thereof
EP2155663B1 (en) 2007-06-15 2017-11-29 Newron Pharmaceuticals S.p.A. Substituted 2-[2-(phenyl)ethylamino]alkaneamide derivatives and their use as sodium and/or calcium channel modulators
GB2453770A (en) * 2007-10-19 2009-04-22 Reckitt Benckiser Healthcare Oral composition comprising a cooling agent
WO2009054964A1 (en) * 2007-10-22 2009-04-30 Concert Pharmaceuticals, Inc. Alpha-aminoamide derivatives
CN104523668B (zh) 2007-12-11 2020-06-09 纽朗制药有限公司 高纯度的2-[4-(3-或2-氟苄氧基)苄氨基]丙酰胺类及其用途
WO2009080470A1 (en) * 2007-12-19 2009-07-02 Newron Pharmaceuticals S.P.A. Alpha-aminoamide derivatives useful in the treatment of psychiatric disorders
WO2009122351A2 (en) * 2008-04-01 2009-10-08 Kangwon National University Anti-parkinsonian compounds mppe
WO2009147430A1 (en) * 2008-06-02 2009-12-10 Generics [Uk] Limited A process for the preparation of enantiomerically pure amines
JP5639999B2 (ja) * 2008-06-02 2014-12-10 ジェネリクス・［ユーケー］・リミテッド アミンの改良調製方法
EP2303330B2 (en) * 2008-06-06 2021-06-16 Pharma Two B Ltd. Pharmaceutical compositions for treatment of parkinson's disease
US20090312436A1 (en) * 2008-06-13 2009-12-17 Ruth Levy Rasagiline for parkinson's disease modification
WO2010010138A1 (en) * 2008-07-24 2010-01-28 Boehringer Ingelheim International Gmbh Pharmaceutical composition comprising pramipexole and a calcium channel blocker for the treatment of parkinson's disease
US20100189791A1 (en) * 2009-01-23 2010-07-29 Teva Pharmaceutical Industries, Ltd. Delayed release rasagiline malate formulation
EP2218444A3 (en) * 2009-01-23 2010-08-25 Teva Pharmaceutical Industries, Ltd. Delayed release rasagiline formulation
EP2314569A1 (en) 2009-10-22 2011-04-27 Merck Patent GmbH Novel polymorphic forms of (S)-2-[4-(3-Fluoro-benzyloxy)-benzylamino]-propionamide mesylate salt and processes of manufacturing thereof
CN102048717B (zh) 2009-10-29 2014-02-19 重庆医药工业研究院有限责任公司 一种稳定的雷沙吉兰组合物
WO2011098456A1 (en) 2010-02-09 2011-08-18 Merck Serono S.A. Safinamide in the treatment of dyskinesia
HUE030504T2 (en) 2010-04-27 2017-05-29 Newron Pharm Spa Process for the preparation of ralfinamide methanesulfonate salts or their R-enantiomers
UA103851C2 (en) 2010-04-30 2013-11-25 ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. Propylaminoindan transdermal composition
CN103476404B (zh) 2011-03-24 2017-09-29 帝国制药美国公司 包含活性剂层和活性剂转化层的透皮组合物
US20150031768A1 (en) * 2011-08-19 2015-01-29 The Trustees Of Princeton University C-halogen bond formation
WO2013081685A1 (en) 2011-08-19 2013-06-06 The Trustees Of Princeton University C-halogen bond formation
EP2776020B1 (en) 2011-11-09 2019-09-11 Teikoku Seiyaku Co., Ltd. Methods for the treatment of skin neoplasms
AU2013338243B2 (en) 2012-11-02 2016-09-29 Teikoku Seiyaku Co., Ltd. Propynylaminoindan transdermal compositions
US9155695B2 (en) 2013-03-14 2015-10-13 Medtronic, Inc. Injectable ropinirole compositions and methods for making and using same
EP3013342B1 (en) 2013-06-27 2021-04-14 Cedars-Sinai Medical Center Adrenoceptors antagonists for the prevention and treatment of neurodegenerative conditions
EP3134077A4 (en) * 2014-04-21 2017-12-20 Civitas Therapeutics, Inc. Rapid relief of motor fluctuations in parkinson's disease
CN106795098B (zh) * 2014-10-02 2020-07-14 默加拜奥伍德有限公司 α-氨基酰胺衍生化合物及包含其的药物组合物
MA42700B1 (fr) * 2015-08-27 2019-12-31 Prexton Therapeutics Sa Dérivé d'oxime de chromone et son utilisation comme modulateur allostérique de récepteurs métabotropiques du glutamate
KR20190016938A (ko) * 2016-03-17 2019-02-19 더 존스 홉킨스 유니버시티 Paris의 파네실화에 의해 파킨슨병을 예방 또는 치료하기 위한 방법
ITUA20163981A1 (it) 2016-05-31 2017-12-01 Zambon Spa Composizioni farmaceutiche comprendenti safinamide
EP3568082A4 (en) * 2017-01-14 2020-12-09 Neurrx, SPC METHOD OF USING HUMAN EXCREMENTS AND SECRETS FOR THE EARLY DETECTION OF PARKINSON'S DISEASE
CN109251155A (zh) * 2017-07-14 2019-01-22 广东东阳光药业有限公司 α-氨基酰胺衍生物及其用途
US11234961B2 (en) * 2017-08-17 2022-02-01 Zi-Qiang Gu Pamoate salt of monoamine anti-Parkinson's agents, method of preparation and use thereof
AU2018357886B2 (en) 2017-11-02 2024-04-18 Zambon S.P.A. Pharmaceutical compositions comprising safinamide
KR102005019B1 (ko) * 2018-04-04 2019-07-31 한국과학기술연구원 뇌졸중의 예방 및 치료용 조성물
CN110938014A (zh) * 2019-11-28 2020-03-31 岳千奥 取代苯氧酰胺衍生物、应用及用于治疗帕金森病的药物
JP2023504876A (ja) * 2019-12-06 2023-02-07 シャンハイ ファーマシューティカルズ ホールディング カンパニー，リミティド 薬物組成物、キット及びその応用
CN110999980A (zh) * 2019-12-19 2020-04-14 新疆石河子职业技术学院（石河子市技工学校） 一种葡萄酒洗浸奶酪加工方法
WO2022047298A1 (en) * 2020-08-31 2022-03-03 Purdue Pharma L.P. Compositions and methods for levodopa delivery

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1140748A (en) 1966-06-23 1969-01-22 Ici Ltd New carboxylic acid derivatives
US3795739A (en) * 1972-02-14 1974-03-05 Hoffmann La Roche Treatment of parkinson disease
US4049663A (en) 1972-06-06 1977-09-20 Allen & Hanburys Limited Ethylene diamine derivatives
FR2480747A1 (fr) 1980-04-17 1981-10-23 Roques Bernard Derives d'acides amines et leur application therapeutique
US4935429A (en) 1985-10-25 1990-06-19 Dackis Charles A Method of treating psychostimulant addiction
EP0252290B1 (en) * 1986-06-10 1992-06-03 CHIESI FARMACEUTICI S.p.A. Pharmaceutical compositions containing levodopa methyl ester, preparation and therapeutic applications thereof
US4970200A (en) 1988-03-01 1990-11-13 Schering Aktiengesellschaft Agent for treatment of Parkinson's disease
IL94466A (en) 1989-05-25 1995-01-24 Erba Carlo Spa Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation
US5221536A (en) * 1990-05-07 1993-06-22 Alza Corporation Dosage form indicated for the management of abnormal posture, tremor and involuntary movement
US5502658A (en) 1990-12-27 1996-03-26 Relin; Arkadi Sampled-continuous probability method of velocity measurement of the object having informatively-structural inhomogeneity
GB9306886D0 (en) 1993-04-01 1993-05-26 Erba Carlo Spa Substituted (arylakoxybenzyl) aminopropanamide derivatives and process for their preparation
IL111240A (en) * 1993-10-18 2001-10-31 Teva Pharma Salts of r(+) - enantiomers of n- propargyl-1-aminoindan and pharmaceutical compositions comprising them
ES2211904T3 (es) * 1995-05-26 2004-07-16 Pfizer Inc. Combinaciones para el tratamiento del parkinsonismo que contienen antagonistas selectivos de nmda.
GB9515412D0 (en) 1995-07-27 1995-09-27 Pharmacia Spa 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
FI109453B (fi) 1999-06-30 2002-08-15 Orion Yhtymae Oyj Farmaseuttinen koostumus
US20020019421A1 (en) * 2000-07-05 2002-02-14 Roni Biberman Compositions and therapy for substance addiction
DE10041479A1 (de) * 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung zur Verabreichung von N-0923
FR2829027A1 (fr) * 2001-08-29 2003-03-07 Aventis Pharma Sa Association avec un antagoniste du recepteur cb1, les compositions pharmaceutiques les contenant et leur utilisation pour le traitement de la maladie de parkinson

Also Published As

Publication number Publication date
NO335537B1 (no) 2014-12-22
PT1613296E (pt) 2009-07-30
WO2004089353A8 (en) 2005-09-01
IL216403A0 (en) 2011-12-29
KR20060010745A (ko) 2006-02-02
NL300752I2 (pl) 2016-07-05
US8283380B2 (en) 2012-10-09
PT2070526E (pt) 2014-03-31
US9492410B2 (en) 2016-11-15
CA2523188C (en) 2012-09-25
ATE435012T1 (de) 2009-07-15
CN102274517B (zh) 2018-08-31
TW200505423A (en) 2005-02-16
CY2015025I1 (el) 2016-04-13
ES2454272T3 (es) 2014-04-10
AU2004228782B2 (en) 2010-05-20
EP1613296B1 (en) 2009-07-01
DK1613296T3 (da) 2009-10-05
ES2326373T3 (es) 2009-10-08
RU2005131422A (ru) 2006-04-27
FR15C0054I1 (fr) 2015-11-09
JP2006522800A (ja) 2006-10-05
HUS1500043I1 (hu) 2018-11-28
CY1109295T1 (el) 2014-07-02
EP2070526A1 (en) 2009-06-17
PL1613296T3 (pl) 2009-12-31
DK2070526T3 (da) 2014-03-24
NZ542910A (en) 2007-10-26
CN102274517A (zh) 2011-12-14
KR101129015B1 (ko) 2012-04-20
IL171331A (en) 2012-03-29
WO2004089353A3 (en) 2004-12-16
NO2015018I1 (no) 2015-08-03
FR15C0054I2 (fr) 2018-01-26
KR20110070929A (ko) 2011-06-24
CY2015025I2 (el) 2016-04-13
US8901176B2 (en) 2014-12-02
AR044007A1 (es) 2005-08-24
AU2004228782A1 (en) 2004-10-21
JP2013067647A (ja) 2013-04-18
SI2070526T1 (sl) 2014-05-30
EP1613296A2 (en) 2006-01-11
NO2015018I2 (no) 2015-07-23
CA2523188A1 (en) 2004-10-21
CY1115286T1 (el) 2017-01-04
DE602004021790D1 (de) 2009-08-13
NO20054640L (no) 2005-12-09
US20070093495A1 (en) 2007-04-26
EP2070526B1 (en) 2014-02-26
LU92782I2 (fr) 2015-09-22
SI1613296T1 (sl) 2009-10-31
RU2342929C2 (ru) 2009-01-10
NO20131417L (no) 2005-12-09
NO334316B1 (no) 2014-02-03
US20150150833A1 (en) 2015-06-04
TWI340640B (en) 2011-04-21
NO20054640D0 (no) 2005-10-10
MXPA05010873A (es) 2006-03-21
CN1771030A (zh) 2006-05-10
IL216403A (en) 2015-01-29
US20130053368A1 (en) 2013-02-28
BRPI0409364A (pt) 2006-04-25
WO2004089353A2 (en) 2004-10-21

Similar Documents

Publication Publication Date Title
HUS1500043I1 (hu) Eljárások Parkinson-kór kezelésére
EP1583750A4 (en) MACROCYCLIC BETA-SEKRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER DISEASE
AU2003286567A8 (en) Methods for the treatment of skin disorders
PT2527315E (pt) Compostos, composições e métodos para o tratamento de doenças da amiloide e sinucleínopatias tais como doença de alzheimer, diabetes do tipo 2, e doença de parkinson
AU2003206413A8 (en) Substituted amino carboxamides for the treatment of alzheimer's disease
IL224393B (en) Preparations for the treatment of Huntington's disease
EP1656359A4 (en) MACROCYCLIC BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE
IL173351A0 (en) Therapy of ocular disorders
EP1817050A4 (en) DIAGNOSIS AND TREATMENT OF MORBUS ALZHEIMER
EP1680145A4 (en) METHODS AND COMPOSITIONS FOR THE TREATMENT OF NEUROLOGICAL DISEASES
GB0329874D0 (en) Compounds useful for the treatment of diseases
GB0320238D0 (en) Treatment of disease
EP1651237A4 (en) METHOD FOR THE TREATMENT OF DERMATOLOGICAL ILLNESSES
AU2003254146A1 (en) Methods for the treatment of parkinson's disease
AU2003303141A8 (en) Hydroxypropyl amides for the treatment of alzheimer's disease
AU2003228464A1 (en) Apparatus for treatment of meniere's disease
EP1832877A4 (en) METHOD FOR THE STUDY OF MORBUS ALZHEIMER
AU2003299101A1 (en) Compounds for the treatment of alzheimer's disease
AU2003277298A8 (en) Pharmaceutical compositions for treatment of parkinson's disease
EP1863510A4 (en) METHOD FOR TREATING PARKINSON DISEASE
AU2003297912A8 (en) Methods for screening compounds for use in the treatment of disease
GB0327975D0 (en) Methods of treatment
EP1786473A4 (en) TREATMENT OF PARKINSON DISEASE AND RELATED DISEASES
AU2003216696A8 (en) Methods for the selection of compounds useful for the treatment of huntington's disease
AU2004907196A0 (en) Use of Naltrexone for Treating Alzheimer's Disease