ATE435012T1 - Verfahren zur behandlung von parkinson-krankheit - Google Patents

Verfahren zur behandlung von parkinson-krankheit

Info

Publication number
ATE435012T1
ATE435012T1 AT04726590T AT04726590T ATE435012T1 AT E435012 T1 ATE435012 T1 AT E435012T1 AT 04726590 T AT04726590 T AT 04726590T AT 04726590 T AT04726590 T AT 04726590T AT E435012 T1 ATE435012 T1 AT E435012T1
Authority
AT
Austria
Prior art keywords
disease
treating parkinson
parkinson
treating
Prior art date
Application number
AT04726590T
Other languages
English (en)
Inventor
Fariello Ruggero
Carlo Cattaneo
Patricia Salvati
Luca Benatti
Original Assignee
Newron Pharm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33159845&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE435012(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Newron Pharm Spa filed Critical Newron Pharm Spa
Application granted granted Critical
Publication of ATE435012T1 publication Critical patent/ATE435012T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT04726590T 2003-04-11 2004-04-08 Verfahren zur behandlung von parkinson-krankheit ATE435012T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46220503P 2003-04-11 2003-04-11
PCT/IB2004/001408 WO2004089353A2 (en) 2003-04-11 2004-04-08 Methods for treatment of parkinson's disease

Publications (1)

Publication Number Publication Date
ATE435012T1 true ATE435012T1 (de) 2009-07-15

Family

ID=33159845

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04726590T ATE435012T1 (de) 2003-04-11 2004-04-08 Verfahren zur behandlung von parkinson-krankheit

Country Status (28)

Country Link
US (3) US8283380B2 (de)
EP (2) EP2070526B1 (de)
JP (2) JP2006522800A (de)
KR (2) KR20110070929A (de)
CN (2) CN1771030A (de)
AR (1) AR044007A1 (de)
AT (1) ATE435012T1 (de)
AU (1) AU2004228782B2 (de)
BR (1) BRPI0409364A (de)
CA (1) CA2523188C (de)
CY (3) CY1109295T1 (de)
DE (1) DE602004021790D1 (de)
DK (2) DK1613296T3 (de)
ES (2) ES2454272T3 (de)
FR (1) FR15C0054I2 (de)
HU (1) HUS1500043I1 (de)
IL (2) IL171331A (de)
LU (1) LU92782I2 (de)
MX (1) MXPA05010873A (de)
NL (1) NL300752I2 (de)
NO (3) NO334316B1 (de)
NZ (1) NZ542910A (de)
PL (2) PL1613296T3 (de)
PT (2) PT1613296E (de)
RU (1) RU2342929C2 (de)
SI (2) SI1613296T1 (de)
TW (1) TWI340640B (de)
WO (1) WO2004089353A2 (de)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
DK1423168T3 (da) 2001-09-03 2006-05-15 Newron Pharm Spa Farmaceutisk præparat omfattende gabapentin eller en analog deraf og et alfa-aminoamid og dets analgetiske anvendelse
EP1438956A1 (de) * 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-Aminoamidderivate die als Antimigränemittel nützlich sind
ES2339021T3 (es) * 2003-08-25 2010-05-14 Newron Pharmaceuticals S.P.A. Derivados de alfa-aminoamida utiles como agentes antiinflamatorios.
EP1588704A1 (de) 2004-04-22 2005-10-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamidderivate zur Behandlung des Restless-Leg-Syndroms und der Suchterkrankungen
US20080096965A1 (en) * 2004-09-10 2008-04-24 Newron Pharmaceuticals S.P.A. (Halobenzyloxy) Benzylamino-Propanamides as Sodium and/or Calcium Channel Selective Modulators
US20070004639A1 (en) * 2005-07-01 2007-01-04 Bodybio, Inc. Methods and compositions for treating Parkinson's disease
WO2007069274A2 (en) * 2005-11-09 2007-06-21 Torrent Pharmaceuticals Limited Pharmaceutical composition comprising a compound having a catechol moiety and an alkalising agent
BRPI0620239B8 (pt) * 2005-12-22 2021-05-25 Newron Pharm Spa derivados de 2-feniletilamino.
CN101032474B (zh) * 2006-03-06 2011-02-16 重庆医药工业研究院有限责任公司 一种治疗或预防神经系统疾病的雷沙吉兰透皮贴片及其制备方法
EP1870097A1 (de) * 2006-06-15 2007-12-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamidederivate zur Behandlung von kognitiven Störungen
US8106056B2 (en) * 2006-06-16 2012-01-31 Solvay Pharmaceuticals B.V. Combination preparations comprising bifeprunox and a dopamine agonist
EA017123B1 (ru) 2006-06-19 2012-10-30 Ньюрон Фармасьютикалс С.П.А. Способ получения 2-[4-(3- и 2-фторбензилокси)бензиламино]пропанамидов
DE102007014947B4 (de) * 2007-03-23 2010-05-27 Axxonis Pharma Ag Stabilisierte wässrige Lösungen von Ergolinverbindungen
CA2684550A1 (en) * 2007-04-24 2008-10-30 Boehringer Ingelheim International Gmbh Combination with an extended release tablet formulation containing pramipexole or a pharmaceutically acceptable salt thereof
JP5440496B2 (ja) 2007-06-15 2014-03-12 ニユーロン・フアーマシユーテイカルズ・エツセ・ピー・アー 置換２−［２−（フェニル）エチルアミノ］アルカンアミド誘導体ならびにナトリウムおよび／またはカルシウムチャネル調節剤としてのこれらの使用
GB2453770A (en) * 2007-10-19 2009-04-22 Reckitt Benckiser Healthcare Oral composition comprising a cooling agent
US20090149544A1 (en) * 2007-10-22 2009-06-11 Concert Pharmaceuticals, Inc. Alpha-aminoamide derivatives
MX2010006278A (es) 2007-12-11 2010-08-31 Newron Pharm Spa Proceso para produccion de 2-[4-(3- o 2-fluorobenciloxi)bencilamin o]propanamidas con un alto grado de pureza.
JP5736175B2 (ja) * 2007-12-19 2015-06-17 ニユーロン・フアーマシユーテイカルズ・エツセ・ピー・アー 精神障害の治療に有用なα−アミノアミド誘導体
US20110027354A1 (en) * 2008-04-01 2011-02-03 Kim Hyoung-Chun Anti-parkinsonian compounds
US20110184071A1 (en) * 2008-06-02 2011-07-28 Vinayak Gore process for the preparation of amines
PL2285769T3 (pl) 2008-06-02 2015-01-30 Generics Uk Ltd Sposób otrzymywania enancjomerycznie czystych amin
HUE037974T2 (hu) * 2008-06-06 2018-09-28 Pharma Two B Ltd Gyógyászati kompozíció Parkinson-kór kezelésére
EA201170018A1 (ru) * 2008-06-13 2011-08-30 Тева Фармасьютикал Индастриз, Лтд. Разагилин для изменения течения болезни паркинсона
WO2010010138A1 (en) * 2008-07-24 2010-01-28 Boehringer Ingelheim International Gmbh Pharmaceutical composition comprising pramipexole and a calcium channel blocker for the treatment of parkinson's disease
EP2218444A3 (de) * 2009-01-23 2010-08-25 Teva Pharmaceutical Industries, Ltd. Rasagilinformulierung mit verzögerter Freisetzung
US20100189791A1 (en) * 2009-01-23 2010-07-29 Teva Pharmaceutical Industries, Ltd. Delayed release rasagiline malate formulation
EP2314569A1 (de) 2009-10-22 2011-04-27 Merck Patent GmbH Neuartige polymorphe Formen von (S)-2-[4-(3-Fluor-benzyloxy)-benzylamino]-Propionamidmesylatsalz und Herstellungsverfahren dafür
CN102048717B (zh) 2009-10-29 2014-02-19 重庆医药工业研究院有限责任公司 一种稳定的雷沙吉兰组合物
WO2011098456A1 (en) * 2010-02-09 2011-08-18 Merck Serono S.A. Safinamide in the treatment of dyskinesia
EP2563355B1 (de) 2010-04-27 2016-06-08 Newron Pharmaceuticals S.p.A. Verfahren zur Herstellung von Ralfinamid-Methansulfonat-Salzen oder deren R-Enantiomere
EP2563347B1 (de) 2010-04-30 2016-10-12 Teikoku Pharma USA, Inc. Transdermale propynylaminoindanzusammensetzungen
US9119799B2 (en) 2011-03-24 2015-09-01 Teikoku Pharma Usa, Inc. Transdermal compositions comprising an active agent layer and an active agent conversion layer
US20140227184A1 (en) 2011-08-19 2014-08-14 The Trustees Of Princeton University C-halogen bond formation
US20150031768A1 (en) * 2011-08-19 2015-01-29 The Trustees Of Princeton University C-halogen bond formation
JP5913614B2 (ja) 2011-11-09 2016-04-27 テイコク ファーマ ユーエスエー インコーポレーテッド 皮膚新生物の処置方法
CN104884046A (zh) 2012-10-22 2015-09-02 丝维塔斯治疗公司 用于快速缓解帕金森病的左旋多巴制剂
US9205061B2 (en) 2012-11-02 2015-12-08 Teikoku Pharma Usa, Inc. Propynylaminoindan transdermal compositions
US9155695B2 (en) 2013-03-14 2015-10-13 Medtronic, Inc. Injectable ropinirole compositions and methods for making and using same
EP3013342B1 (de) 2013-06-27 2021-04-14 Cedars-Sinai Medical Center Adrenorezeptor-antagonisten zur vorbeugung und behandlung neurodegenerativer erkrankungen
BR112016024502A8 (pt) * 2014-04-21 2021-06-29 Civitas Therapeutics Inc uso de uma dose de partículas finas (fdp) de levodopa na fabricação de um medicamento
JP6446131B2 (ja) 2014-10-02 2018-12-26 メガバイオウッド カンパニー，リミテッド α−アミノアミド誘導体化合物及びこれを含む薬学的組成物
HRP20192250T1 (hr) * 2015-08-27 2020-05-15 Prexton Therapeutics Sa Derivat kromon oksima koji prodire u mozak za liječenje diskinezije uzrokovane levodopom
JP2019510088A (ja) * 2016-03-17 2019-04-11 ザ ジョンズ ホプキンス ユニバーシティーＴｈｅ Ｊｏｈｎｓ Ｈｏｐｋｉｎｓ Ｕｎｉｖｅｒｓｉｔｙ Ｐａｒｉｓのファルネシル化によってパーキンソン病を予防または治療する方法
ITUA20163981A1 (it) 2016-05-31 2017-12-01 Zambon Spa Composizioni farmaceutiche comprendenti safinamide
EP3568082A4 (de) * 2017-01-14 2020-12-09 Neurrx, SPC Verfahren zur verwendung menschlicher exkremente und sekrete zur früherkennung von morbus parkinson
CN109251155A (zh) * 2017-07-14 2019-01-22 广东东阳光药业有限公司 α-氨基酰胺衍生物及其用途
US11234961B2 (en) * 2017-08-17 2022-02-01 Zi-Qiang Gu Pamoate salt of monoamine anti-Parkinson's agents, method of preparation and use thereof
CN111432806A (zh) 2017-11-02 2020-07-17 萨宝公司 包含沙芬酰胺的药物组合物
KR102005019B1 (ko) * 2018-04-04 2019-07-31 한국과학기술연구원 뇌졸중의 예방 및 치료용 조성물
AU2020346695A1 (en) * 2019-09-12 2022-04-28 Achieve Life Sciences, Inc. Compositions comprising cytisine in the treatment and/or prevention of addiction in subjects in need thereof
LU101477B1 (en) * 2019-11-12 2021-05-14 Univ Luxembourg An inhibitor of an iron-containing hydrogenase of a methanogenic archaeon for use in the treatment or prevention of a parkinsonian condition
CN110938014A (zh) * 2019-11-28 2020-03-31 岳千奥 取代苯氧酰胺衍生物、应用及用于治疗帕金森病的药物
CN112915083A (zh) * 2019-12-06 2021-06-08 上海医药集团股份有限公司 药物组合物、成套药盒及其应用
CN110999980A (zh) * 2019-12-19 2020-04-14 新疆石河子职业技术学院（石河子市技工学校） 一种葡萄酒洗浸奶酪加工方法
US20230181508A1 (en) * 2020-08-31 2023-06-15 Purdue Pharma L.P. Compositions and methods for levodopa delivery
US20220315651A1 (en) * 2021-03-08 2022-10-06 Prothena Biosciences Limited Treatment of Parkinson's Disease
KR102790040B1 (ko) * 2021-06-24 2025-04-01 연세대학교 산학협력단 도파민 미모톱 기능 합성 펩티드 및 이를 포함하는 mao-b 억제제

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1140748A (en) 1966-06-23 1969-01-22 Ici Ltd New carboxylic acid derivatives
US3795739A (en) * 1972-02-14 1974-03-05 Hoffmann La Roche Treatment of parkinson disease
US4049663A (en) 1972-06-06 1977-09-20 Allen & Hanburys Limited Ethylene diamine derivatives
FR2480747A1 (fr) 1980-04-17 1981-10-23 Roques Bernard Derives d'acides amines et leur application therapeutique
US4935429A (en) 1985-10-25 1990-06-19 Dackis Charles A Method of treating psychostimulant addiction
DE3779500T2 (de) * 1986-06-10 1993-01-21 Chiesi Farma Spa Levodopa-methyl-ester enthaltende pharmazeutische zusammensetzungen, ihre herstellung und therapeutische verwendungen.
US4970200A (en) 1988-03-01 1990-11-13 Schering Aktiengesellschaft Agent for treatment of Parkinson's disease
IL94466A (en) 1989-05-25 1995-01-24 Erba Carlo Spa Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation
US5221536A (en) * 1990-05-07 1993-06-22 Alza Corporation Dosage form indicated for the management of abnormal posture, tremor and involuntary movement
US5502658A (en) 1990-12-27 1996-03-26 Relin; Arkadi Sampled-continuous probability method of velocity measurement of the object having informatively-structural inhomogeneity
GB9306886D0 (en) 1993-04-01 1993-05-26 Erba Carlo Spa Substituted (arylakoxybenzyl) aminopropanamide derivatives and process for their preparation
IL111240A (en) * 1993-10-18 2001-10-31 Teva Pharma Salts of r(+) - enantiomers of n- propargyl-1-aminoindan and pharmaceutical compositions comprising them
FI974323A0 (fi) * 1995-05-26 1997-11-25 Pfizer Selektiivisiä NMDA-antagonisteja sisältäviä yhdistelmiä parkinsonismin hoitoa varten
GB9515412D0 (en) * 1995-07-27 1995-09-27 Pharmacia Spa 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
FI109453B (fi) 1999-06-30 2002-08-15 Orion Yhtymae Oyj Farmaseuttinen koostumus
US20020019421A1 (en) * 2000-07-05 2002-02-14 Roni Biberman Compositions and therapy for substance addiction
DE10041479A1 (de) * 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung zur Verabreichung von N-0923
FR2829027A1 (fr) * 2001-08-29 2003-03-07 Aventis Pharma Sa Association avec un antagoniste du recepteur cb1, les compositions pharmaceutiques les contenant et leur utilisation pour le traitement de la maladie de parkinson

Also Published As

Publication number Publication date
IL171331A (en) 2012-03-29
NO334316B1 (no) 2014-02-03
TW200505423A (en) 2005-02-16
SI1613296T1 (sl) 2009-10-31
CN102274517A (zh) 2011-12-14
DK2070526T3 (da) 2014-03-24
NO335537B1 (no) 2014-12-22
DK1613296T3 (da) 2009-10-05
CN1771030A (zh) 2006-05-10
NO2015018I2 (no) 2015-07-23
PT2070526E (pt) 2014-03-31
NZ542910A (en) 2007-10-26
CA2523188C (en) 2012-09-25
AR044007A1 (es) 2005-08-24
RU2342929C2 (ru) 2009-01-10
BRPI0409364A (pt) 2006-04-25
ES2454272T3 (es) 2014-04-10
TWI340640B (en) 2011-04-21
CY2015025I1 (el) 2016-04-13
US9492410B2 (en) 2016-11-15
NL300752I2 (de) 2016-07-05
PL2070526T3 (pl) 2014-08-29
HUS1500043I1 (hu) 2018-11-28
EP2070526B1 (de) 2014-02-26
PT1613296E (pt) 2009-07-30
KR20110070929A (ko) 2011-06-24
US20150150833A1 (en) 2015-06-04
NO2015018I1 (no) 2015-08-03
WO2004089353A8 (en) 2005-09-01
JP2013067647A (ja) 2013-04-18
CA2523188A1 (en) 2004-10-21
EP1613296A2 (de) 2006-01-11
KR101129015B1 (ko) 2012-04-20
NO20131417L (no) 2005-12-09
CY1115286T1 (el) 2017-01-04
DE602004021790D1 (de) 2009-08-13
JP2006522800A (ja) 2006-10-05
US20070093495A1 (en) 2007-04-26
KR20060010745A (ko) 2006-02-02
NO20054640D0 (no) 2005-10-10
FR15C0054I2 (fr) 2018-01-26
US20130053368A1 (en) 2013-02-28
ES2326373T3 (es) 2009-10-08
WO2004089353A3 (en) 2004-12-16
EP2070526A1 (de) 2009-06-17
RU2005131422A (ru) 2006-04-27
US8283380B2 (en) 2012-10-09
FR15C0054I1 (fr) 2015-11-09
CY2015025I2 (el) 2016-04-13
AU2004228782B2 (en) 2010-05-20
WO2004089353A2 (en) 2004-10-21
MXPA05010873A (es) 2006-03-21
CY1109295T1 (el) 2014-07-02
PL1613296T3 (pl) 2009-12-31
EP1613296B1 (de) 2009-07-01
IL216403A0 (en) 2011-12-29
IL216403A (en) 2015-01-29
CN102274517B (zh) 2018-08-31
US8901176B2 (en) 2014-12-02
SI2070526T1 (sl) 2014-05-30
AU2004228782A1 (en) 2004-10-21
LU92782I2 (fr) 2015-09-22
NO20054640L (no) 2005-12-09

Similar Documents

Publication Publication Date Title
ATE435012T1 (de) Verfahren zur behandlung von parkinson-krankheit
EP1482962A4 (de) Verfahren zur behandlung von trx-vermittelten erkrankungen
DE60102016D1 (de) Verfahren zur behandlung von beweggungsstörungen
DE602004023829D1 (de) Verfahren zur behandlung von sinuskopfschmerzen
EP1651164A4 (de) Zusammensetzung und verfahren zur behandlung von neurologischen erkrankungen
DE602004002519D1 (de) Verfahren zur Oberflächenbehandlung von Metallen
EP1565230A4 (de) Materialzusammensetzungen und verwandtesysteme und verfahren zur behandlung von herzerkrankungen
DE60122242D1 (de) Verfahren zur Bekämpfung von Saatkrankheiten
DE60122532D1 (de) Verfahren zur behandlung von mehreren bohrlochintervallen
EP1626730A4 (de) Verfahren, gerät und zusammensetzung zur behandlung von akne
EP1701664A4 (de) System und verfahren zur behandlung von gewebe
EP1595852A4 (de) Verfahren zur behandlung von ammoniakalischen stickstoffenthaltendem wasser
EP1641581A4 (de) Verfahren und vorrichtung zur herstellung von metallverbindungen
ATE411803T1 (de) Verfahren zur behandlung von schwerer herzinsuffizienz und medikament dafür
ATA17552001A (de) Verfahren zur behandlung säurehältiger abwässer
EP1635801A4 (de) Verfahren zur behandlung und prävention von herzarrhythmie
DE60223688D1 (de) Verfahren zur behandlung von multiplem myelom
EP1651237A4 (de) Verfahren zur behandlung von dermatologischen erkrankungen
ATE328880T1 (de) Tetrazolderivate und verfahren zur behandlung von stoffwechselbedingten erkrankungen damit
DE502004008042D1 (de) Verfahren zum umformen von blechen
ATE374799T1 (de) Verfahren zur behandlung von pigmenten in partikulärer form
EP1695061A4 (de) Verfahren zur behandlung neurologischer störungen
ATE432918T1 (de) Verfahren zur herstellung von cpla 2-inhibitoren
DE602004010548D1 (de) Verfahren zur behandlung von tierhäuten
DE602004031740D1 (de) Verfahren zur herstellung von konzentraten

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1613296

Country of ref document: EP

UEP Publication of translation of european patent specification

Ref document number: 1613296

Country of ref document: EP