PL2285769T3 - Sposób otrzymywania enancjomerycznie czystych amin - Google Patents

Sposób otrzymywania enancjomerycznie czystych amin

Info

Publication number
PL2285769T3
PL2285769T3 PL09757802T PL09757802T PL2285769T3 PL 2285769 T3 PL2285769 T3 PL 2285769T3 PL 09757802 T PL09757802 T PL 09757802T PL 09757802 T PL09757802 T PL 09757802T PL 2285769 T3 PL2285769 T3 PL 2285769T3
Authority
PL
Poland
Prior art keywords
preparation
enantiomerically pure
pure amines
amines
enantiomerically
Prior art date
Application number
PL09757802T
Other languages
English (en)
Inventor
Vinayak Gore
Bindu Manojkumar
Sandeep Sonawane
Dattatrey Kokane
Sinderpal Tank
Original Assignee
Generics Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Generics Uk Ltd filed Critical Generics Uk Ltd
Publication of PL2285769T3 publication Critical patent/PL2285769T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/82—Purification; Separation; Stabilisation; Use of additives
    • C07C209/86—Separation
    • C07C209/88—Separation of optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
    • C07C211/41—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems
    • C07C211/42—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems with six-membered aromatic rings being part of the condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Psychology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL09757802T 2008-06-02 2009-06-02 Sposób otrzymywania enancjomerycznie czystych amin PL2285769T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN973KO2008 2008-06-02
EP09757802.5A EP2285769B1 (en) 2008-06-02 2009-06-02 A process for the preparation of enantiomerically pure amines
PCT/GB2009/050608 WO2009147430A1 (en) 2008-06-02 2009-06-02 A process for the preparation of enantiomerically pure amines

Publications (1)

Publication Number Publication Date
PL2285769T3 true PL2285769T3 (pl) 2015-01-30

Family

ID=40874479

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09757802T PL2285769T3 (pl) 2008-06-02 2009-06-02 Sposób otrzymywania enancjomerycznie czystych amin

Country Status (10)

Country Link
US (2) US8569545B2 (pl)
EP (1) EP2285769B1 (pl)
JP (1) JP5487440B2 (pl)
CN (2) CN103896779B (pl)
AU (1) AU2009254927B2 (pl)
CA (2) CA2723869C (pl)
CY (1) CY1115577T1 (pl)
NZ (1) NZ589486A (pl)
PL (1) PL2285769T3 (pl)
WO (1) WO2009147430A1 (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009147430A1 (en) * 2008-06-02 2009-12-10 Generics [Uk] Limited A process for the preparation of enantiomerically pure amines
EP2681186B1 (en) 2011-03-03 2016-05-11 Synthon BV Process of resolution of 1-aminoindan
EP3041824A1 (en) 2013-09-03 2016-07-13 Universidade de Évora Process for preparing cyclic chiral amines and alcohols by intramolecular catalytic arylation of boronic acid or ester aldehydes and imine substrates
CN104326920B (zh) * 2014-10-13 2016-03-16 江苏清泉化学股份有限公司 一种去除间苯二甲胺中杂质的方法
CN105018560B (zh) * 2015-08-13 2018-09-14 陈永军 动态动力学拆分制备(s)-6-甲氧基-1-氨基茚满
CN105087742B (zh) * 2015-08-18 2018-09-14 陈永军 动态动力学拆分制备r-6-羟基-1-氨基茚满
CN105063161B (zh) * 2015-08-18 2018-11-09 陈永军 一种r-1-氨基茚满的制备方法
CN105177103B (zh) * 2015-08-19 2019-03-12 陈永军 一种r-6-羟基-1-氨基茚满的制备方法
AR110150A1 (es) * 2016-11-09 2019-02-27 Roivant Sciences Gmbh Procesos para la preparación de inhibidores de tph1

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US3198834A (en) 1964-07-27 1965-08-03 Snc Science Union Et Compagnie Optical isomers of trifluoromethylated phenethylamines
US3728388A (en) 1970-08-10 1973-04-17 Sterling Drug Inc 1-amino-2,3-disubstituted cyclopropenylium salts
US3855227A (en) * 1972-05-08 1974-12-17 C Hollander ({31 )-di-o-isopropylidene-2-keto-l-gulonates
US3912761A (en) 1972-05-08 1975-10-14 Hoffmann La Roche (-)-Di-O-isopropylidene-2-keto-L-gulonates
US3928621A (en) 1974-10-10 1975-12-23 Hoffmann La Roche Antiinflammatory 2-(2-aminoalkylamino)-1,2-diphenylethanols
JPS5283938A (en) 1976-01-01 1977-07-13 Hoffmann La Roche Antiiinflammation agent and process for preparing same
HU187775B (en) 1982-07-14 1986-02-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu New process for producing propargile-amines of pharmaceutical activity
US4833273A (en) 1986-02-03 1989-05-23 Warner-Lambert Company Process for the resolution of 1-aminoindanes
EP0279844A4 (en) 1986-09-02 1990-06-05 Du Pont AFLÖSUNG VON DE dl-METHYL-3-4- (2-HYDROXY-3-ISOPROPYLAMINO) PROPOXY] PHENYLPROPIONAT (DL-ESMOLOL)].
CS269271B1 (en) 1988-05-30 1990-04-11 Hajicek Josef Method of selegiline's hydrochloride production
US5744500A (en) 1990-01-03 1998-04-28 Teva Pharmaceutical Industries, Ltd. Use of R-enantiomer of N-propargyl-1-aminoindan, salts, and compositions thereof
IL92952A (en) 1990-01-03 1994-06-24 Teva Pharma R-enantiomers of n-propargyl-1-aminoindan compounds, their preparation and pharmaceutical compositions containing them
US5030725A (en) 1990-02-06 1991-07-09 Eli Lilly And Company Method of resolving cis 3-amino-4-[2-(2-furyl)eth-1-yl]-1-methoxycarbonylmethyl-azetidin-2-one using (-)-DAG
CN1031995C (zh) 1991-01-02 1996-06-12 奥韦特有限公司 N-炔丙基-1-氨基茚满的r-对映体的制法
IL111240A (en) 1993-10-18 2001-10-31 Teva Pharma Salts of r(+) - enantiomers of n- propargyl-1-aminoindan and pharmaceutical compositions comprising them
CA2180841C (en) 1994-01-10 2007-03-27 Sasson Cohen 1-aminoindan derivatives and compositions thereof
US5877218A (en) * 1994-01-10 1999-03-02 Teva Pharmaceutical Industries, Ltd. Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives
JP2840560B2 (ja) 1994-11-22 1998-12-24 キノイン・ジヨージセル・エーシユ・ベジエーセテイ・テルメーケク・ジヤーラ・エル・テー 塩化プロパルギルアンモニウム誘導体の製造方法
IL141690A (en) * 2001-02-27 2004-06-20 Isp Finetech Ltd Process for preparation of rasagiline and its salts
AR044007A1 (es) * 2003-04-11 2005-08-24 Newron Pharmaceuticals Inc Metodos para el tratamiento de la enfermedad de parkinson
CA2600008A1 (en) 2005-02-22 2006-11-16 Teva Pharmaceutical Industries Ltd. Improved process for the synthesis of enantiomeric indanylamine derivatives
US7491847B2 (en) 2005-11-17 2009-02-17 Teva Pharmaceutical Industries, Ltd. Methods for isolating propargylated aminoindans
CN101062897B (zh) 2006-04-25 2011-11-23 重庆医药工业研究院有限责任公司 一种制备2，3-二氢-1h-茚-1-胺及其衍生物的改进方法
AU2007334428B2 (en) 2006-12-14 2014-05-29 Teva Pharmaceutical Industries, Ltd. Crystalline solid rasagiline base
EP1987816A1 (de) 2007-04-30 2008-11-05 Ratiopharm GmbH Adsorbate eines Rasagilinsalzes mit einem wasserlöslichen Hilfsstoff
WO2009147430A1 (en) * 2008-06-02 2009-12-10 Generics [Uk] Limited A process for the preparation of enantiomerically pure amines
WO2009147432A1 (en) 2008-06-02 2009-12-10 Generics [Uk] Limited An improved process for the preparation of amines
EP2321258A1 (en) 2008-07-30 2011-05-18 Generics [UK] Limited Polymorphic form of rasagiline mesylate

Also Published As

Publication number Publication date
JP2011522023A (ja) 2011-07-28
CA2812006A1 (en) 2009-12-10
CN102123980B (zh) 2014-05-07
US20110251288A1 (en) 2011-10-13
NZ589486A (en) 2012-08-31
AU2009254927B2 (en) 2014-03-13
US8569545B2 (en) 2013-10-29
CN103896779B (zh) 2015-12-30
CN102123980A (zh) 2011-07-13
CA2723869C (en) 2013-07-16
CY1115577T1 (el) 2017-01-04
CN103896779A (zh) 2014-07-02
JP5487440B2 (ja) 2014-05-07
EP2285769A1 (en) 2011-02-23
EP2285769B1 (en) 2014-08-13
US8809589B2 (en) 2014-08-19
AU2009254927A1 (en) 2009-12-10
US20130303741A1 (en) 2013-11-14
CA2723869A1 (en) 2009-12-10
WO2009147430A1 (en) 2009-12-10
CA2812006C (en) 2016-07-26

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