|
US7994298B2
(en)
|
2004-09-24 |
2011-08-09 |
Trustees Of Dartmouth College |
Chimeric NK receptor and methods for treating cancer
|
|
AU2006204459B2
(en)
|
2005-01-05 |
2012-11-01 |
F-Star Therapeutics Limited |
Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions
|
|
CA2915168C
(en)
†
|
2007-01-30 |
2017-05-23 |
Epivax, Inc. |
Regulatory t cell epitopes, compositions and uses thereof
|
|
AU2008304555A1
(en)
*
|
2007-09-25 |
2009-04-02 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Modified T cell receptors and related materials and methods
|
|
US9493578B2
(en)
|
2009-09-02 |
2016-11-15 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
|
US12492376B2
(en)
|
2009-10-29 |
2025-12-09 |
The Trustees Of Dartmouth College |
T-cell receptor-deficient T cell compositions
|
|
WO2011059836A2
(en)
|
2009-10-29 |
2011-05-19 |
Trustees Of Dartmouth College |
T cell receptor-deficient t cell compositions
|
|
US9273283B2
(en)
|
2009-10-29 |
2016-03-01 |
The Trustees Of Dartmouth College |
Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
|
|
CA2806252C
(en)
|
2010-07-29 |
2019-05-14 |
Xencor, Inc. |
Antibodies with modified isoelectric points
|
|
US9833476B2
(en)
|
2011-08-31 |
2017-12-05 |
The Trustees Of Dartmouth College |
NKP30 receptor targeted therapeutics
|
|
US10851178B2
(en)
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
|
US12466897B2
(en)
|
2011-10-10 |
2025-11-11 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
|
WO2013169691A1
(en)
|
2012-05-07 |
2013-11-14 |
Trustees Of Dartmouth College |
Anti-b7-h6 antibody, fusion proteins, and methods of using the same
|
|
WO2014018863A1
(en)
|
2012-07-27 |
2014-01-30 |
The Board Of Trustees Of The University Of Illinois |
Engineering t-cell receptors
|
|
US10713726B1
(en)
|
2013-01-13 |
2020-07-14 |
United Services Automobile Association (Usaa) |
Determining insurance policy modifications using informatic sensor data
|
|
US9701759B2
(en)
|
2013-01-14 |
2017-07-11 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US10487155B2
(en)
|
2013-01-14 |
2019-11-26 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US11053316B2
(en)
|
2013-01-14 |
2021-07-06 |
Xencor, Inc. |
Optimized antibody variable regions
|
|
US10968276B2
(en)
|
2013-03-12 |
2021-04-06 |
Xencor, Inc. |
Optimized anti-CD3 variable regions
|
|
US10131710B2
(en)
|
2013-01-14 |
2018-11-20 |
Xencor, Inc. |
Optimized antibody variable regions
|
|
US9605084B2
(en)
|
2013-03-15 |
2017-03-28 |
Xencor, Inc. |
Heterodimeric proteins
|
|
HRP20191865T1
(hr)
|
2013-01-14 |
2020-01-10 |
Xencor, Inc. |
Novi heterodimerni proteini
|
|
WO2014113510A1
(en)
|
2013-01-15 |
2014-07-24 |
Xencor, Inc. |
Rapid clearance of antigen complexes using novel antibodies
|
|
LT2956175T
(lt)
|
2013-02-15 |
2017-12-11 |
The Regents Of The University Of California |
Chimerinis antigeno receptorius ir jo panaudojimo būdai
|
|
US9499855B2
(en)
|
2013-03-14 |
2016-11-22 |
Elwha Llc |
Compositions, methods, and computer systems related to making and administering modified T cells
|
|
US9587237B2
(en)
|
2013-03-14 |
2017-03-07 |
Elwha Llc |
Compositions, methods, and computer systems related to making and administering modified T cells
|
|
EP2971288A4
(en)
*
|
2013-03-14 |
2016-12-07 |
Elwha Llc |
COMPOSITIONS, METHODS AND COMPUTER SYSTEMS FOR THE MANUFACTURE AND ADMINISTRATION OF MODIFIED T CELLS
|
|
CA3093606A1
(en)
|
2013-03-15 |
2014-09-18 |
Xencor, Inc. |
Heterodimeric proteins for induction of t cells
|
|
US10106624B2
(en)
|
2013-03-15 |
2018-10-23 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US10519242B2
(en)
|
2013-03-15 |
2019-12-31 |
Xencor, Inc. |
Targeting regulatory T cells with heterodimeric proteins
|
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
|
JP2016526536A
(ja)
*
|
2013-06-14 |
2016-09-05 |
ザ ユニバーシティ オブ ヒューストン システム |
修飾されたキメラ抗原受容体による腫瘍新生血管構造の標的化
|
|
US9409139B2
(en)
|
2013-08-05 |
2016-08-09 |
Twist Bioscience Corporation |
De novo synthesized gene libraries
|
|
US9947051B1
(en)
|
2013-08-16 |
2018-04-17 |
United Services Automobile Association |
Identifying and recommending insurance policy products/services using informatic sensor data
|
|
GB201317929D0
(en)
*
|
2013-10-10 |
2013-11-27 |
Ucl Business Plc |
Chimeric antigen receptor
|
|
EP3071594A4
(en)
*
|
2013-11-22 |
2017-05-03 |
The Board of Trustees of the University of Illionis |
Engineered high-affinity human t cell receptors
|
|
US11087404B1
(en)
|
2014-01-10 |
2021-08-10 |
United Services Automobile Association (Usaa) |
Electronic sensor management
|
|
US11416941B1
(en)
|
2014-01-10 |
2022-08-16 |
United Services Automobile Association (Usaa) |
Electronic sensor management
|
|
US10552911B1
(en)
|
2014-01-10 |
2020-02-04 |
United Services Automobile Association (Usaa) |
Determining status of building modifications using informatics sensor data
|
|
US12100050B1
(en)
|
2014-01-10 |
2024-09-24 |
United Services Automobile Association (Usaa) |
Electronic sensor management
|
|
US11847666B1
(en)
|
2014-02-24 |
2023-12-19 |
United Services Automobile Association (Usaa) |
Determining status of building modifications using informatics sensor data
|
|
EP3243831A1
(en)
|
2014-02-27 |
2017-11-15 |
Ucl Business Plc |
Variants of the proliferation-inducing ligand (april)
|
|
US10614525B1
(en)
|
2014-03-05 |
2020-04-07 |
United Services Automobile Association (Usaa) |
Utilizing credit and informatic data for insurance underwriting purposes
|
|
EP3954713A3
(en)
|
2014-03-28 |
2022-03-30 |
Xencor, Inc. |
Bispecific antibodies that bind to cd38 and cd3
|
|
WO2016014725A1
(en)
|
2014-07-22 |
2016-01-28 |
The University Of Notre Dame Du Lac |
Molecular constructs and uses thereof
|
|
EP3223907A2
(en)
|
2014-11-26 |
2017-10-04 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and cd38
|
|
CN116333153A
(zh)
|
2014-11-26 |
2023-06-27 |
森科股份有限公司 |
结合cd3和肿瘤抗原的异二聚体抗体
|
|
US10259887B2
(en)
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
|
WO2016105450A2
(en)
|
2014-12-22 |
2016-06-30 |
Xencor, Inc. |
Trispecific antibodies
|
|
CA2975852A1
(en)
|
2015-02-04 |
2016-08-11 |
Twist Bioscience Corporation |
Methods and devices for de novo oligonucleic acid assembly
|
|
US10227411B2
(en)
|
2015-03-05 |
2019-03-12 |
Xencor, Inc. |
Modulation of T cells with bispecific antibodies and FC fusions
|
|
WO2016172377A1
(en)
|
2015-04-21 |
2016-10-27 |
Twist Bioscience Corporation |
Devices and methods for oligonucleic acid library synthesis
|
|
KR20180029201A
(ko)
|
2015-05-18 |
2018-03-20 |
티씨알2 테라퓨틱스 인크. |
융합 단백질을 이용하는 tcr 리프로그래밍을 위한 조성물 및 방법
|
|
AU2016324296A1
(en)
|
2015-09-18 |
2018-04-12 |
Twist Bioscience Corporation |
Oligonucleic acid variant libraries and synthesis thereof
|
|
CN108698012A
(zh)
|
2015-09-22 |
2018-10-23 |
特韦斯特生物科学公司 |
用于核酸合成的柔性基底
|
|
WO2017087723A1
(en)
*
|
2015-11-19 |
2017-05-26 |
The Regents Of The University Of California |
Conditionally repressible immune cell receptors and methods of use thereof
|
|
CN108603307A
(zh)
|
2015-12-01 |
2018-09-28 |
特韦斯特生物科学公司 |
功能化表面及其制备
|
|
KR20180085800A
(ko)
|
2015-12-07 |
2018-07-27 |
젠코어 인코포레이티드 |
Cd3 및 psma에 결합하는 이종이합체성 항체
|
|
EA201891589A1
(ru)
|
2016-01-08 |
2019-01-31 |
Те Риджентс Оф Те Юниверсити Оф Калифорния |
Условно активные гетеродимерные полипептиды и способы их применения
|
|
AU2017233035B2
(en)
*
|
2016-03-16 |
2021-08-05 |
Neximmune, Inc. |
Production of antigen-specific T-cells
|
|
IL263542B2
(en)
|
2016-06-14 |
2024-10-01 |
Xencor Inc |
Bispecific antibodies inhibit immunological checkpoint
|
|
KR20190020341A
(ko)
|
2016-06-28 |
2019-02-28 |
젠코어 인코포레이티드 |
소마토스타틴 수용체 2에 결합하는 이종이량체 항체
|
|
WO2018026953A1
(en)
|
2016-08-02 |
2018-02-08 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
CA3034769A1
(en)
|
2016-08-22 |
2018-03-01 |
Twist Bioscience Corporation |
De novo synthesized nucleic acid libraries
|
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
|
CN110248724B
(zh)
|
2016-09-21 |
2022-11-18 |
特韦斯特生物科学公司 |
基于核酸的数据存储
|
|
IL302917A
(en)
|
2016-10-07 |
2023-07-01 |
Tcr2 Therapeutics Inc |
Compositions and methods for t-cell receptors reprogramming using fusion proteins
|
|
CN110214148A
(zh)
|
2016-10-14 |
2019-09-06 |
Xencor股份有限公司 |
含有IL-15/IL-15Rα Fc融合蛋白和PD-1抗体片段的双特异性异源二聚体融合蛋白
|
|
JP7291396B2
(ja)
|
2016-11-22 |
2023-06-15 |
ティーシーアール2 セラピューティクス インク. |
融合タンパク質を用いたtcrの再プログラミングのための組成物及び方法
|
|
CN110366613A
(zh)
*
|
2016-12-16 |
2019-10-22 |
特韦斯特生物科学公司 |
免疫突触的变体文库及其合成
|
|
PT3583120T
(pt)
|
2017-02-17 |
2022-12-15 |
Denali Therapeutics Inc |
Polipeptídeos de ligação ao recetor de transferrina manipulados
|
|
WO2018156792A1
(en)
|
2017-02-22 |
2018-08-30 |
Twist Bioscience Corporation |
Nucleic acid based data storage
|
|
CN110913865A
(zh)
|
2017-03-15 |
2020-03-24 |
特韦斯特生物科学公司 |
免疫突触的变体文库及其合成
|
|
WO2018231864A1
(en)
|
2017-06-12 |
2018-12-20 |
Twist Bioscience Corporation |
Methods for seamless nucleic acid assembly
|
|
IL271205B2
(en)
|
2017-06-12 |
2025-02-01 |
Twist Bioscience Corp |
Methods for assembling continuous nucleic acids
|
|
AU2018291497A1
(en)
|
2017-06-30 |
2020-01-16 |
Xencor, Inc. |
Targeted heterodimeric Fc fusion proteins containing IL-15/IL-15Ra and antigen binding domains
|
|
ES2871146T3
(es)
|
2017-07-14 |
2021-10-28 |
Immatics Biotechnologies Gmbh |
Molécula de polipéptido con especificidad dual mejorada
|
|
US11407837B2
(en)
|
2017-09-11 |
2022-08-09 |
Twist Bioscience Corporation |
GPCR binding proteins and synthesis thereof
|
|
KR102637566B1
(ko)
|
2017-10-20 |
2024-02-16 |
트위스트 바이오사이언스 코포레이션 |
폴리뉴클레오타이드 합성을 위한 가열된 나노웰
|
|
US10981992B2
(en)
|
2017-11-08 |
2021-04-20 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
|
AU2018366199A1
(en)
|
2017-11-08 |
2020-05-28 |
Xencor, Inc. |
Bispecific and monospecific antibodies using novel anti-PD-1 sequences
|
|
MX2020006322A
(es)
|
2017-12-19 |
2020-09-18 |
Xencor Inc |
Proteinas de fusion il-2 fc modificadas.
|
|
CN112041438B
(zh)
|
2018-01-04 |
2025-05-23 |
特韦斯特生物科学公司 |
基于dna的数字信息存储
|
|
CN112469477A
(zh)
|
2018-04-04 |
2021-03-09 |
Xencor股份有限公司 |
与成纤维细胞活化蛋白结合的异源二聚体抗体
|
|
AU2019256539A1
(en)
|
2018-04-18 |
2020-11-26 |
Xencor, Inc. |
PD-1 targeted heterodimeric fusion proteins containing IL-15/IL-15Ra Fc-fusion proteins and PD-1 antigen binding domains and uses thereof
|
|
EP3781598A1
(en)
|
2018-04-18 |
2021-02-24 |
Xencor, Inc. |
Tim-3 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and tim-3 antigen binding domains
|
|
CA3100739A1
(en)
|
2018-05-18 |
2019-11-21 |
Twist Bioscience Corporation |
Polynucleotides, reagents, and methods for nucleic acid hybridization
|
|
IL321690A
(en)
|
2018-07-26 |
2025-08-01 |
Curevac Netherlands B V |
Cancer vaccines for uterine cancer
|
|
CA3106574A1
(en)
|
2018-07-26 |
2020-01-30 |
Frame Pharmaceuticals B.V. |
Arid1a, cdkn2a, kmt2b, kmt2d, tp53 and pten vaccines for cancer
|
|
EP3827265A1
(en)
|
2018-07-26 |
2021-06-02 |
Frame Pharmaceuticals B.V. |
Cancer vaccines for kidney cancer
|
|
EP3827263A1
(en)
|
2018-07-26 |
2021-06-02 |
Frame Pharmaceuticals B.V. |
Cancer vaccines for colorectal cancer
|
|
CA3106564A1
(en)
|
2018-07-26 |
2020-01-30 |
Frame Pharmaceuticals B.V. |
Cancer vaccines for breast cancer
|
|
SG11202103192RA
(en)
|
2018-10-03 |
2021-04-29 |
Xencor Inc |
Il-12 heterodimeric fc-fusion proteins
|
|
CA3124980A1
(en)
|
2018-12-26 |
2020-07-02 |
Twist Bioscience Corporation |
Highly accurate de novo polynucleotide synthesis
|
|
KR20210143766A
(ko)
|
2019-02-26 |
2021-11-29 |
트위스트 바이오사이언스 코포레이션 |
Glp1 수용체에 대한 변이체 핵산 라이브러리
|
|
CN113785057A
(zh)
|
2019-02-26 |
2021-12-10 |
特韦斯特生物科学公司 |
用于抗体优化的变异核酸文库
|
|
AU2020232605A1
(en)
|
2019-03-01 |
2021-10-21 |
Xencor, Inc. |
Heterodimeric antibodies that bind ENPP3 and CD3
|
|
JP2022550497A
(ja)
|
2019-06-21 |
2022-12-02 |
ツイスト バイオサイエンス コーポレーション |
バーコードに基づいた核酸配列アセンブリ
|
|
AU2020355027A1
(en)
|
2019-09-23 |
2022-04-21 |
Twist Bioscience Corporation |
Antibodies that bind CD3 Epsilon
|
|
CA3155629A1
(en)
|
2019-09-23 |
2021-04-01 |
Twist Bioscience Corporation |
Variant nucleic acid libraries for crth2
|
|
WO2021231976A1
(en)
|
2020-05-14 |
2021-11-18 |
Xencor, Inc. |
Heterodimeric antibodies that bind prostate specific membrane antigen (psma) and cd3
|
|
KR102607909B1
(ko)
|
2020-08-19 |
2023-12-01 |
젠코어 인코포레이티드 |
항-cd28 조성물
|
|
JP2024511319A
(ja)
|
2021-03-09 |
2024-03-13 |
ゼンコア インコーポレイテッド |
Cd3及びcldn6に結合するヘテロ二量体抗体
|
|
JP2024509274A
(ja)
|
2021-03-10 |
2024-02-29 |
ゼンコア インコーポレイテッド |
Cd3及びgpc3に結合するヘテロ二量体抗体
|
|
BR112023022765A2
(pt)
|
2021-05-05 |
2024-01-02 |
Immatics Biotechnologies Gmbh |
Proteínas de ligação ao antígeno que ligam especificamente o prame
|
|
GB202113673D0
(en)
*
|
2021-09-24 |
2021-11-10 |
Reflection Therapeutics Ltd |
Targeted cell therapies
|