|
WO2006036445A2
(en)
|
2004-09-24 |
2006-04-06 |
Trustees Of Dartmouth College |
Chimeric nk receptor and methods for treating cancer
|
|
ATE423140T1
(de)
|
2005-01-05 |
2009-03-15 |
F Star Biotech Forsch & Entw |
Synthetische immunoglobulindomänen mit in regionen des moleküls, die sich von den die komplementarität bestimmenden bereichen unterscheiden, modifizierten bindeeigenschaften
|
|
EP2423220B1
(en)
†
|
2007-01-30 |
2015-04-29 |
Epivax, Inc. |
Regulatory t cell epitopes, compositions and uses thereof
|
|
CA2700278A1
(en)
*
|
2007-09-25 |
2009-04-02 |
The United States Of America, As Represented By The Secretary, Departmen T Of Health And Human Services |
Modified t cell receptors and related materials and methods
|
|
US9493578B2
(en)
|
2009-09-02 |
2016-11-15 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
|
US12492376B2
(en)
|
2009-10-29 |
2025-12-09 |
The Trustees Of Dartmouth College |
T-cell receptor-deficient T cell compositions
|
|
US9273283B2
(en)
|
2009-10-29 |
2016-03-01 |
The Trustees Of Dartmouth College |
Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
|
|
WO2011059836A2
(en)
|
2009-10-29 |
2011-05-19 |
Trustees Of Dartmouth College |
T cell receptor-deficient t cell compositions
|
|
EP2598530A2
(en)
|
2010-07-29 |
2013-06-05 |
Xencor, Inc. |
Antibodies with modified isoelectric points
|
|
US9833476B2
(en)
|
2011-08-31 |
2017-12-05 |
The Trustees Of Dartmouth College |
NKP30 receptor targeted therapeutics
|
|
US10851178B2
(en)
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
|
US12466897B2
(en)
|
2011-10-10 |
2025-11-11 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
|
CN104395344B
(zh)
|
2012-05-07 |
2019-08-13 |
达特茅斯大学理事会 |
抗b7-h6抗体、融合蛋白及其使用方法
|
|
NZ741124A
(en)
*
|
2012-07-27 |
2019-11-29 |
Univ Illinois |
Engineering t-cell receptors
|
|
US10713726B1
(en)
|
2013-01-13 |
2020-07-14 |
United Services Automobile Association (Usaa) |
Determining insurance policy modifications using informatic sensor data
|
|
US10131710B2
(en)
|
2013-01-14 |
2018-11-20 |
Xencor, Inc. |
Optimized antibody variable regions
|
|
KR102391731B1
(ko)
|
2013-01-14 |
2022-04-27 |
젠코어 인코포레이티드 |
신규한 이형이량체 단백질
|
|
US11053316B2
(en)
|
2013-01-14 |
2021-07-06 |
Xencor, Inc. |
Optimized antibody variable regions
|
|
US9701759B2
(en)
|
2013-01-14 |
2017-07-11 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US10968276B2
(en)
|
2013-03-12 |
2021-04-06 |
Xencor, Inc. |
Optimized anti-CD3 variable regions
|
|
US9605084B2
(en)
|
2013-03-15 |
2017-03-28 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US10487155B2
(en)
|
2013-01-14 |
2019-11-26 |
Xencor, Inc. |
Heterodimeric proteins
|
|
WO2014113510A1
(en)
|
2013-01-15 |
2014-07-24 |
Xencor, Inc. |
Rapid clearance of antigen complexes using novel antibodies
|
|
IL305629A
(en)
|
2013-02-15 |
2023-11-01 |
Univ California |
Chimeric antigen receptor and methods of using it
|
|
WO2014159435A1
(en)
*
|
2013-03-14 |
2014-10-02 |
Elwha Llc |
Compositions, methods, and computer systems related to making and administering modified t cells
|
|
US9499855B2
(en)
|
2013-03-14 |
2016-11-22 |
Elwha Llc |
Compositions, methods, and computer systems related to making and administering modified T cells
|
|
US9587237B2
(en)
|
2013-03-14 |
2017-03-07 |
Elwha Llc |
Compositions, methods, and computer systems related to making and administering modified T cells
|
|
US10106624B2
(en)
|
2013-03-15 |
2018-10-23 |
Xencor, Inc. |
Heterodimeric proteins
|
|
EP3421495A3
(en)
|
2013-03-15 |
2019-05-15 |
Xencor, Inc. |
Modulation of t cells with bispecific antibodies and fc fusions
|
|
US10519242B2
(en)
|
2013-03-15 |
2019-12-31 |
Xencor, Inc. |
Targeting regulatory T cells with heterodimeric proteins
|
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
|
CN105431456A
(zh)
*
|
2013-06-14 |
2016-03-23 |
休斯敦系统大学 |
用修饰的嵌合抗原受体靶向肿瘤新生血管
|
|
KR102160389B1
(ko)
|
2013-08-05 |
2020-09-28 |
트위스트 바이오사이언스 코포레이션 |
드 노보 합성된 유전자 라이브러리
|
|
US9710858B1
(en)
|
2013-08-16 |
2017-07-18 |
United Services Automobile Association (Usaa) |
Insurance policy alterations using informatic sensor data
|
|
GB201317929D0
(en)
*
|
2013-10-10 |
2013-11-27 |
Ucl Business Plc |
Chimeric antigen receptor
|
|
JP6476182B2
(ja)
*
|
2013-11-22 |
2019-02-27 |
ザ ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ イリノイ |
改変された高親和性ヒトt細胞受容体
|
|
US10552911B1
(en)
|
2014-01-10 |
2020-02-04 |
United Services Automobile Association (Usaa) |
Determining status of building modifications using informatics sensor data
|
|
US11416941B1
(en)
|
2014-01-10 |
2022-08-16 |
United Services Automobile Association (Usaa) |
Electronic sensor management
|
|
US11087404B1
(en)
|
2014-01-10 |
2021-08-10 |
United Services Automobile Association (Usaa) |
Electronic sensor management
|
|
US12100050B1
(en)
|
2014-01-10 |
2024-09-24 |
United Services Automobile Association (Usaa) |
Electronic sensor management
|
|
US11847666B1
(en)
|
2014-02-24 |
2023-12-19 |
United Services Automobile Association (Usaa) |
Determining status of building modifications using informatics sensor data
|
|
EP3243831A1
(en)
|
2014-02-27 |
2017-11-15 |
Ucl Business Plc |
Variants of the proliferation-inducing ligand (april)
|
|
US10614525B1
(en)
|
2014-03-05 |
2020-04-07 |
United Services Automobile Association (Usaa) |
Utilizing credit and informatic data for insurance underwriting purposes
|
|
PL3122781T3
(pl)
|
2014-03-28 |
2020-06-15 |
Xencor, Inc. |
Dwuswoiste przeciwciała, które wiążą się z CD38 i CD3
|
|
WO2016014725A1
(en)
|
2014-07-22 |
2016-01-28 |
The University Of Notre Dame Du Lac |
Molecular constructs and uses thereof
|
|
US10259887B2
(en)
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
|
JP6696982B2
(ja)
|
2014-11-26 |
2020-05-20 |
ゼンコー・インコーポレイテッドXencor、 Inc. |
Cd3および腫瘍抗原に結合するヘテロ二量体抗体
|
|
HK1245171A1
(zh)
|
2014-11-26 |
2018-08-24 |
Xencor, Inc. |
结合cd3和cd38的异二聚体抗体
|
|
US10428155B2
(en)
|
2014-12-22 |
2019-10-01 |
Xencor, Inc. |
Trispecific antibodies
|
|
CA2975852A1
(en)
|
2015-02-04 |
2016-08-11 |
Twist Bioscience Corporation |
Methods and devices for de novo oligonucleic acid assembly
|
|
US10227411B2
(en)
|
2015-03-05 |
2019-03-12 |
Xencor, Inc. |
Modulation of T cells with bispecific antibodies and FC fusions
|
|
WO2016172377A1
(en)
|
2015-04-21 |
2016-10-27 |
Twist Bioscience Corporation |
Devices and methods for oligonucleic acid library synthesis
|
|
EP3770168A1
(en)
|
2015-05-18 |
2021-01-27 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
KR20180050411A
(ko)
|
2015-09-18 |
2018-05-14 |
트위스트 바이오사이언스 코포레이션 |
올리고핵산 변이체 라이브러리 및 그의 합성
|
|
WO2017053450A1
(en)
|
2015-09-22 |
2017-03-30 |
Twist Bioscience Corporation |
Flexible substrates for nucleic acid synthesis
|
|
EP3377523A4
(en)
*
|
2015-11-19 |
2019-06-19 |
The Regents of The University of California |
CONDITIONALLY REPRIMATABLE IMMUNOCELL RECEPTORS AND METHOD FOR USE THEREOF
|
|
EP3384077A4
(en)
|
2015-12-01 |
2019-05-08 |
Twist Bioscience Corporation |
FUNCTIONALIZED SURFACES AND MANUFACTURE THEREOF
|
|
EP3387013B1
(en)
|
2015-12-07 |
2022-06-08 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and psma
|
|
MX2018008416A
(es)
|
2016-01-08 |
2019-11-11 |
Univ California |
Polipéptidos heterodímericos condicionalmente activos y métodos para su uso.
|
|
WO2017161092A1
(en)
*
|
2016-03-16 |
2017-09-21 |
Neximmune, Inc. |
Production of antigen-specific t-cells
|
|
CA3026151A1
(en)
|
2016-06-14 |
2017-12-21 |
Xencor, Inc. |
Bispecific checkpoint inhibitor antibodies
|
|
RU2019102008A
(ru)
|
2016-06-28 |
2020-07-28 |
Ксенкор, Инк. |
Гетеродимерные антитела, которые связывают рецептор соматостатина 2-го типа
|
|
WO2018026953A1
(en)
|
2016-08-02 |
2018-02-08 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
WO2018038772A1
(en)
|
2016-08-22 |
2018-03-01 |
Twist Bioscience Corporation |
De novo synthesized nucleic acid libraries
|
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
|
EP4664304A3
(en)
|
2016-09-21 |
2026-01-21 |
Atlas Data Storage, Inc. |
Nucleic acid based data storage
|
|
BR112019007100A2
(pt)
|
2016-10-07 |
2019-06-25 |
Tcr2 Therapeutics Inc |
composições e métodos para reprogramação de receptores de célula t com o uso de proteínas de fusão
|
|
MX2019004327A
(es)
|
2016-10-14 |
2019-10-14 |
Xencor Inc |
Proteinas de fusion heterodimericas biespecificas que contienen proteinas de fusion fc il-15/il-15ra y fragmentos de anticuerpo pd-1.
|
|
CN110177803A
(zh)
|
2016-11-22 |
2019-08-27 |
T细胞受体治疗公司 |
用于使用融合蛋白进行tcr重新编程的组合物和方法
|
|
GB2573069A
(en)
*
|
2016-12-16 |
2019-10-23 |
Twist Bioscience Corp |
Variant libraries of the immunological synapse and synthesis thereof
|
|
RS63818B1
(sr)
|
2017-02-17 |
2023-01-31 |
Denali Therapeutics Inc |
Konstruisani polipeptidi za vezivanje za receptor transferina
|
|
WO2018156792A1
(en)
|
2017-02-22 |
2018-08-30 |
Twist Bioscience Corporation |
Nucleic acid based data storage
|
|
CA3056388A1
(en)
|
2017-03-15 |
2018-09-20 |
Twist Bioscience Corporation |
Variant libraries of the immunological synapse and synthesis thereof
|
|
IL271205B2
(en)
|
2017-06-12 |
2025-02-01 |
Twist Bioscience Corp |
Methods for assembling continuous nucleic acids
|
|
WO2018231864A1
(en)
|
2017-06-12 |
2018-12-20 |
Twist Bioscience Corporation |
Methods for seamless nucleic acid assembly
|
|
AU2018291497A1
(en)
|
2017-06-30 |
2020-01-16 |
Xencor, Inc. |
Targeted heterodimeric Fc fusion proteins containing IL-15/IL-15Ra and antigen binding domains
|
|
US20190016802A1
(en)
|
2017-07-14 |
2019-01-17 |
Immatics Biotechnologies Gmbh |
Dual specificity polypeptide molecule
|
|
CN111566125A
(zh)
|
2017-09-11 |
2020-08-21 |
特韦斯特生物科学公司 |
Gpcr结合蛋白及其合成
|
|
CN111565834B
(zh)
|
2017-10-20 |
2022-08-26 |
特韦斯特生物科学公司 |
用于多核苷酸合成的加热的纳米孔
|
|
AU2018366199A1
(en)
|
2017-11-08 |
2020-05-28 |
Xencor, Inc. |
Bispecific and monospecific antibodies using novel anti-PD-1 sequences
|
|
US10981992B2
(en)
|
2017-11-08 |
2021-04-20 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
|
JP7765181B2
(ja)
|
2017-12-19 |
2025-11-06 |
ゼンコア インコーポレイテッド |
改変されたil-2 fc融合タンパク質
|
|
IL312616B2
(en)
|
2018-01-04 |
2025-08-01 |
Twist Bioscience Corp |
Dna-based digital information storage
|
|
CN112469477A
(zh)
|
2018-04-04 |
2021-03-09 |
Xencor股份有限公司 |
与成纤维细胞活化蛋白结合的异源二聚体抗体
|
|
CA3097593A1
(en)
|
2018-04-18 |
2019-10-24 |
Xencor, Inc. |
Pd-1 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and pd-1 antigen binding domains and uses thereof
|
|
KR20210003814A
(ko)
|
2018-04-18 |
2021-01-12 |
젠코어 인코포레이티드 |
IL-15/IL-15Rα Fc-융합 단백질 및 TIM-3 항원 결합 도메인을 함유하는 TIM-3 표적화 이종이량체 융합 단백질
|
|
EP3814497A4
(en)
|
2018-05-18 |
2022-03-02 |
Twist Bioscience Corporation |
POLYNUCLEOTIDES, REAGENTS AND METHODS FOR NUCLEIC ACID HYBRIDIZATION
|
|
CA3106574A1
(en)
|
2018-07-26 |
2020-01-30 |
Frame Pharmaceuticals B.V. |
Arid1a, cdkn2a, kmt2b, kmt2d, tp53 and pten vaccines for cancer
|
|
EP3827262A1
(en)
|
2018-07-26 |
2021-06-02 |
Frame Pharmaceuticals B.V. |
Cancer vaccines for breast cancer
|
|
CA3106567A1
(en)
|
2018-07-26 |
2020-01-30 |
Frame Pharmaceuticals B.V. |
Cancer vaccines for kidney cancer
|
|
WO2020022901A1
(en)
|
2018-07-26 |
2020-01-30 |
Frame Pharmaceuticals B.V. |
Cancer vaccines for uterine cancer
|
|
CA3106573A1
(en)
|
2018-07-26 |
2020-01-30 |
Frame Pharmaceuticals B.V. |
Cancer vaccines for colorectal cancer
|
|
KR102884523B1
(ko)
|
2018-10-03 |
2025-11-10 |
젠코어 인코포레이티드 |
IL-12 이종이량체 Fc-융합 단백질
|
|
US12466892B2
(en)
|
2018-11-08 |
2025-11-11 |
The Regents Of The University Of California |
Systems and methods for targeting cancer cells
|
|
EP3902816A4
(en)
|
2018-12-26 |
2022-09-14 |
Twist Bioscience Corporation |
HIGH-PRECISION DE NOVO POLYNUCLEOTIDE SYNTHESIS
|
|
CA3131689A1
(en)
|
2019-02-26 |
2020-09-03 |
Twist Bioscience Corporation |
Variant nucleic acid libraries for glp1 receptor
|
|
KR20210144698A
(ko)
|
2019-02-26 |
2021-11-30 |
트위스트 바이오사이언스 코포레이션 |
항체 최적화를 위한 변이 핵산 라이브러리
|
|
EP3930850A1
(en)
|
2019-03-01 |
2022-01-05 |
Xencor, Inc. |
Heterodimeric antibodies that bind enpp3 and cd3
|
|
EP3987019A4
(en)
|
2019-06-21 |
2023-04-19 |
Twist Bioscience Corporation |
Barcode-based nucleic acid sequence assembly
|
|
US12091777B2
(en)
|
2019-09-23 |
2024-09-17 |
Twist Bioscience Corporation |
Variant nucleic acid libraries for CRTH2
|
|
CN115023440B
(zh)
|
2019-09-23 |
2025-09-12 |
特韦斯特生物科学公司 |
结合CD3ε的抗体
|
|
AU2020400030B2
(en)
|
2019-12-09 |
2026-05-21 |
Twist Bioscience Corporation |
Variant nucleic acid libraries for adenosine receptors
|
|
EP4149632A1
(en)
|
2020-05-14 |
2023-03-22 |
Xencor, Inc. |
Heterodimeric antibodies that bind msln and cd3
|
|
WO2021231976A1
(en)
|
2020-05-14 |
2021-11-18 |
Xencor, Inc. |
Heterodimeric antibodies that bind prostate specific membrane antigen (psma) and cd3
|
|
US11919958B2
(en)
|
2020-08-19 |
2024-03-05 |
Xencor, Inc. |
Anti-CD28 compositions
|
|
EP4305067A1
(en)
|
2021-03-09 |
2024-01-17 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and cldn6
|
|
US11859012B2
(en)
|
2021-03-10 |
2024-01-02 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and GPC3
|
|
WO2022233956A1
(en)
|
2021-05-05 |
2022-11-10 |
Immatics Biotechnologies Gmbh |
Antigen binding proteins specifically binding prame
|
|
IL311003A
(en)
|
2021-08-25 |
2024-04-01 |
Denali Therapeutics Inc |
Anti-2HER antibodies and methods of using them
|
|
GB202113673D0
(en)
*
|
2021-09-24 |
2021-11-10 |
Reflection Therapeutics Ltd |
Targeted cell therapies
|