PL1877390T3 - Związki benzizoksazolopiperazynowe i sposoby ich stosowania - Google Patents

Związki benzizoksazolopiperazynowe i sposoby ich stosowania

Info

Publication number
PL1877390T3
PL1877390T3 PL06751667T PL06751667T PL1877390T3 PL 1877390 T3 PL1877390 T3 PL 1877390T3 PL 06751667 T PL06751667 T PL 06751667T PL 06751667 T PL06751667 T PL 06751667T PL 1877390 T3 PL1877390 T3 PL 1877390T3
Authority
PL
Poland
Prior art keywords
methods
piperazine compounds
benzisoxazole
benzisoxazole piperazine
compounds
Prior art date
Application number
PL06751667T
Other languages
English (en)
Polish (pl)
Inventor
James F White
Daniel Coughlin
Dale M Edgar
Michael Solomon
David G Hangauer
Kazumi Shiosaki
Original Assignee
Hypnion Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hypnion Inc filed Critical Hypnion Inc
Priority claimed from PCT/US2006/016059 external-priority patent/WO2006116615A1/en
Publication of PL1877390T3 publication Critical patent/PL1877390T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL06751667T 2005-04-26 2006-04-26 Związki benzizoksazolopiperazynowe i sposoby ich stosowania PL1877390T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US67520205P 2005-04-26 2005-04-26
PCT/US2006/016059 WO2006116615A1 (en) 2005-04-26 2006-04-26 Benzisoxazole piperazine compounds and methods of use thereof
EP06751667A EP1877390B1 (en) 2005-04-26 2006-04-26 Benzisoxazole piperazine compounds and methods of use thereof

Publications (1)

Publication Number Publication Date
PL1877390T3 true PL1877390T3 (pl) 2010-08-31

Family

ID=36754209

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06751667T PL1877390T3 (pl) 2005-04-26 2006-04-26 Związki benzizoksazolopiperazynowe i sposoby ich stosowania

Country Status (15)

Country Link
US (3) US7494998B2 (enExample)
EP (2) EP1877390B1 (enExample)
JP (2) JP2008539267A (enExample)
CN (1) CN101208314B (enExample)
AT (2) ATE459621T1 (enExample)
AU (1) AU2006239302B2 (enExample)
CA (2) CA2606473C (enExample)
CY (1) CY1110026T1 (enExample)
DE (2) DE602006012650D1 (enExample)
DK (1) DK1877390T3 (enExample)
ES (2) ES2340066T3 (enExample)
MX (1) MX2007013352A (enExample)
PL (1) PL1877390T3 (enExample)
PT (1) PT1877390E (enExample)
WO (1) WO2006116614A1 (enExample)

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JP4198733B2 (ja) 2003-07-22 2008-12-17 アリーナ ファーマシューティカルズ， インコーポレイテッド 関連性障害の予防および処置に有用な、５−ｈｔ２ａセロトニンレセプターのモジュレーターとしてのジアリールおよびアリールへテロアリールウレア誘導体
SA05260357B1 (ar) 2004-11-19 2008-09-08 ارينا فارماسيتو تيكالز ، أنك مشتقات 3_فينيل_بيرازول كمعدلات لمستقبل سيروتينين 5_ht2a مفيدة في علاج الاضطرابات المتعلقه به
ES2340066T3 (es) * 2005-04-26 2010-05-28 Hypnion, Inc. Compuestos de benzisoxazol piperidina y procedimiento de uso de los mismos.
NZ571829A (en) 2006-05-18 2011-10-28 Arena Pharm Inc Crystalline forms and processes for the preparation of phenyl-pyrazoles useful as modulators of the 5-HT2A serotonin receptor
AU2007254244C1 (en) 2006-05-18 2014-07-31 Arena Pharmaceuticals, Inc. 3-pyrazolyl-benzamide-4-ethers, secondary amines and derivatives thereof as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto
JP5406018B2 (ja) 2006-05-18 2014-02-05 アリーナ ファーマシューティカルズ， インコーポレイテッド ５−ｈｔ２ａセロトニンレセプターに関連する障害の処置に有用な５−ｈｔ２ａセロトニンレセプターのモジュレーターとしての１級アミン、およびその誘導体
US7762006B2 (en) * 2006-06-14 2010-07-27 Siestamed, Technologies Medical equipment drying device
TWI415845B (zh) 2006-10-03 2013-11-21 Arena Pharm Inc 用於治療與５-ｈｔ2ａ血清素受體相關聯病症之作為５-ｈｔ2ａ血清素受體之調節劑的吡唑衍生物
US8622991B2 (en) 2007-03-19 2014-01-07 Insuline Medical Ltd. Method and device for drug delivery
US8827979B2 (en) * 2007-03-19 2014-09-09 Insuline Medical Ltd. Drug delivery device
US20100286467A1 (en) * 2007-03-19 2010-11-11 Benny Pesach Device for drug delivery and associated connections thereto
US9220837B2 (en) * 2007-03-19 2015-12-29 Insuline Medical Ltd. Method and device for drug delivery
US9567327B2 (en) 2007-08-15 2017-02-14 Arena Pharmaceuticals, Inc. Imidazo[1,2-a]pyridine derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto
EP2231229A1 (en) 2007-12-18 2010-09-29 Insuline Medical Ltd. Drug delivery device with sensor for closed-loop operation
US20110021538A1 (en) 2008-04-02 2011-01-27 Arena Pharmaceuticals, Inc. Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
US20090263449A1 (en) * 2008-04-09 2009-10-22 Surmodics, Inc. Delivery of nucleic acid complexes from materials including negatively charged groups
SG157299A1 (en) * 2008-05-09 2009-12-29 Agency Science Tech & Res Diagnosis and treatment of kawasaki disease
CN102264354B (zh) 2008-10-28 2015-03-25 艾尼纳制药公司 用于治疗5-ht2a5-羟色胺受体相关障碍的5-ht2a5-羟色胺受体调节剂组合物
US9126946B2 (en) 2008-10-28 2015-09-08 Arena Pharmaceuticals, Inc. Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)urea and crystalline forms related thereto
CN102245137A (zh) 2008-11-07 2011-11-16 茵苏莱恩医药有限公司 用于药物递送的装置和方法
US8555875B2 (en) 2008-12-23 2013-10-15 Map Pharmaceuticals, Inc. Inhalation devices and related methods for administration of sedative hypnotic compounds
WO2011075596A1 (en) 2009-12-18 2011-06-23 Arena Pharmaceuticals, Inc. Crystalline forms of certain 3-phenyl-pyrazole derivatives as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto
US8565107B2 (en) 2010-09-24 2013-10-22 Hand Held Products, Inc. Terminal configurable for use within an unknown regulatory domain
WO2016201373A1 (en) 2015-06-12 2016-12-15 Axovant Sciences Ltd. Diaryl and arylheteroaryl urea derivatives useful for the prophylaxis and treatment of rem sleep behavior disorder
HK1247555A1 (zh) 2015-07-15 2018-09-28 Axovant Sciences Gmbh 用於预防和治疗与神经变性疾病相关的幻觉的作为5-ht2a血清素受体的调节剂的二芳基脲和芳基杂芳基脲衍生物
GB201810092D0 (en) 2018-06-20 2018-08-08 Ctxt Pty Ltd Compounds
EP3986890B9 (en) 2019-06-18 2025-04-16 Pfizer Inc. Benzisoxazole sulfonamide derivatives
CN114981264B (zh) * 2019-12-24 2024-07-26 住友制药株式会社 脂肪酸酰胺衍生物
JP7655885B2 (ja) * 2021-06-30 2025-04-02 住友ファーマ株式会社 脂肪族酸アミド誘導体を含有する医薬組成物

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US5364866A (en) 1989-05-19 1994-11-15 Hoechst-Roussel Pharmaceuticals, Inc. Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics
US5776963A (en) 1989-05-19 1998-07-07 Hoechst Marion Roussel, Inc. 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility
FR2654104B1 (fr) * 1989-11-07 1992-01-03 Adir Nouveaux derives du 1,2-benzisoxazole, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
DK60593D0 (da) 1993-05-26 1993-05-26 Novo Nordisk As Kemiske forbindelser, deres fremstilling og anvendelse
FR2742052B1 (fr) 1995-12-12 1998-04-10 Esteve Labor Dr Utilisation des derives 1-(4-(4-aryl (ou heteroaryl)-1-piper azinyl)-buty)-1h-azole pour le traitement de la depression, des troubles obsessifs compulsifs, l'apnee du sommeil, les dysfonctions sexuelles, l'emese et le mal des transports
ZA9610738B (en) 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
WO1997049698A1 (en) 1996-06-21 1997-12-31 Glaxo Group Limited Piperidine acetic acid derivatives and their use in the treatment of thrombotic disorders
CA2316388C (en) * 1997-12-25 2009-09-08 Meiji Seika Kaisha Ltd. Tetrahydrobenzindole derivative
US6331541B1 (en) 1998-12-18 2001-12-18 Soo S. Ko N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
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ES2165274B1 (es) * 1999-06-04 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
GB0117577D0 (en) * 2001-02-16 2001-09-12 Aventis Pharm Prod Inc Novel heterocyclic substituted carbonyl derivatives and their use as dopamine D receptor ligands
EP1632483B1 (en) 2001-02-16 2008-10-29 Aventis Pharmaceuticals Inc. Heterocyclic substituted carbonyl derivatives and their use as dopamine d3 receptor ligands
US7355042B2 (en) 2001-10-16 2008-04-08 Hypnion, Inc. Treatment of CNS disorders using CNS target modulators
ES2201899B1 (es) * 2002-04-01 2005-06-01 Almirall Prodesfarma, S.A. Derivados de la azaindolilpiperidina como agentes antihistaminicos y antialergicos.
ES2340066T3 (es) 2005-04-26 2010-05-28 Hypnion, Inc. Compuestos de benzisoxazol piperidina y procedimiento de uso de los mismos.

Also Published As

Publication number Publication date
EP1877405A1 (en) 2008-01-16
US20080214539A1 (en) 2008-09-04
AU2006239302B2 (en) 2011-07-07
JP5049267B2 (ja) 2012-10-17
JP2008539267A (ja) 2008-11-13
ATE461925T1 (de) 2010-04-15
EP1877405B1 (en) 2010-03-03
US8088778B2 (en) 2012-01-03
MX2007013352A (es) 2008-03-26
CY1110026T1 (el) 2015-01-14
US7494998B2 (en) 2009-02-24
PT1877390E (pt) 2010-05-31
EP1877390B1 (en) 2010-03-24
US8129410B2 (en) 2012-03-06
EP1877390A1 (en) 2008-01-16
JP2008539268A (ja) 2008-11-13
ATE459621T1 (de) 2010-03-15
ES2340066T3 (es) 2010-05-28
CA2606473C (en) 2013-08-13
US20090163514A1 (en) 2009-06-25
DK1877390T3 (da) 2010-05-31
CN101208314A (zh) 2008-06-25
AU2006239302A1 (en) 2006-11-02
DE602006012650D1 (de) 2010-04-15
CN101208314B (zh) 2010-12-08
WO2006116614A1 (en) 2006-11-02
US20070004752A1 (en) 2007-01-04
CA2606471C (en) 2014-02-11
CA2606473A1 (en) 2006-11-02
CA2606471A1 (en) 2006-11-02
ES2341127T3 (es) 2010-06-15
DE602006013115D1 (de) 2010-05-06

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