PL171026B1 - Sposób wytwarzania nowej 2-podstawionej chinoliny PL PL PL PL - Google Patents
Sposób wytwarzania nowej 2-podstawionej chinoliny PL PL PL PLInfo
- Publication number
- PL171026B1 PL171026B1 PL92314698A PL31469892A PL171026B1 PL 171026 B1 PL171026 B1 PL 171026B1 PL 92314698 A PL92314698 A PL 92314698A PL 31469892 A PL31469892 A PL 31469892A PL 171026 B1 PL171026 B1 PL 171026B1
- Authority
- PL
- Poland
- Prior art keywords
- formula
- straight
- carbon atoms
- chlorine
- fluorine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Electrically Operated Instructional Devices (AREA)
- Earth Drilling (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4105551A DE4105551A1 (de) | 1991-02-22 | 1991-02-22 | 2-substituierte chinoline, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL171026B1 true PL171026B1 (pl) | 1997-02-28 |
Family
ID=6425643
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL92314698A PL171026B1 (pl) | 1991-02-22 | 1992-02-19 | Sposób wytwarzania nowej 2-podstawionej chinoliny PL PL PL PL |
| PL92293534A PL170726B1 (pl) | 1991-02-22 | 1992-02-19 | Sposób wytwarzania nowej 2-podstawionej chinoliny PL PL PL PL |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL92293534A PL170726B1 (pl) | 1991-02-22 | 1992-02-19 | Sposób wytwarzania nowej 2-podstawionej chinoliny PL PL PL PL |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0499926B1 (enExample) |
| JP (1) | JPH0592957A (enExample) |
| KR (1) | KR920016424A (enExample) |
| AT (1) | ATE142623T1 (enExample) |
| AU (1) | AU641585B2 (enExample) |
| CZ (1) | CZ282723B6 (enExample) |
| DE (2) | DE4105551A1 (enExample) |
| DK (1) | DK0499926T3 (enExample) |
| ES (1) | ES2091958T3 (enExample) |
| FI (1) | FI920732L (enExample) |
| GR (1) | GR3021014T3 (enExample) |
| HU (1) | HUT67037A (enExample) |
| IE (1) | IE75728B1 (enExample) |
| IL (1) | IL101009A (enExample) |
| MY (1) | MY108459A (enExample) |
| NZ (1) | NZ241654A (enExample) |
| PL (2) | PL171026B1 (enExample) |
| RU (1) | RU2077532C1 (enExample) |
| TW (1) | TW200463B (enExample) |
| ZA (1) | ZA921268B (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4226649A1 (de) * | 1992-08-12 | 1994-02-17 | Bayer Ag | Neue isobutylsubstituierte Methansulfonyl-chinolylmethoxyphenyl-cycloalkylessigsäureaminole |
| US5304563A (en) * | 1991-02-22 | 1994-04-19 | Bayer Aktiengesellschaft | 2-substituted quinolines, and their use in medicaments |
| DE4112533A1 (de) * | 1991-04-17 | 1992-10-22 | Bayer Ag | Verfahren zur herstellung von enantiomerenreinen substituierten (chinolin-2-yl-methoxy)phenyl-essigsaeuren |
| US5391555A (en) * | 1991-11-12 | 1995-02-21 | Miles Inc. | Methods for treating inflammatory bowel disease with leukotriene synthesis inhibitors |
| TW232013B (enExample) * | 1992-04-24 | 1994-10-11 | Takeda Pharm Industry Co Ltd | |
| DE4219765A1 (de) * | 1992-06-17 | 1993-12-23 | Bayer Ag | Substituierte (Benzothiazolyl- und Chinoxalyl-methoxy)phenylessigsäurederivate |
| DE4301900A1 (de) * | 1993-01-25 | 1994-07-28 | Bayer Ag | 2-Oxochinolin-1-yl-methylphenylessigsäurederivate |
| ES2061406B1 (es) * | 1993-05-07 | 1995-06-01 | Uriach & Cia Sa J | Nuevos derivados de la 2-(quinolina) con actividad farmacologica. |
| US5491172A (en) * | 1993-05-14 | 1996-02-13 | Warner-Lambert Company | N-acyl sulfamic acid esters (or thioesters), N-acyl sulfonamides, and N-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents |
| IL109431A (en) * | 1993-05-14 | 2001-01-11 | Warner Lambert Co | Pharmaceutical compositions containing n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters), for regulating plasma cholesterol concentration, and certain such novel compounds |
| ATE188377T1 (de) * | 1993-06-29 | 2000-01-15 | Takeda Chemical Industries Ltd | Chinoline oder chinazolin-derivate und deren verwendung zur herstellung eines medikaments für die behandlung von osteoporose |
| DE4443892A1 (de) * | 1994-12-09 | 1996-06-13 | Bayer Ag | 4-(Chinolin-2-yl-methoxy)-phenyl-essigsäurederivate |
| DE4443891A1 (de) | 1994-12-09 | 1996-06-13 | Bayer Ag | Heterocyclisch substituierte Oxy-phenyl-(phenyl)glycinolamide |
| ES2226377T3 (es) * | 1998-05-11 | 2005-03-16 | Takeda Chemical Industries, Ltd. | Derivados de acido oxiimino-alcalino con actividad hipoglucemica e hipolipidemica. |
| GB9818641D0 (en) * | 1998-08-26 | 1998-10-21 | Rh Ne Poulenc Rorer Limited | Chemical compounds |
| HRP20010795A2 (en) * | 1999-04-28 | 2003-02-28 | Aventis Pharma Gmbh | Di-aryl acid derivatives as ppar receptor ligands |
| RU2177317C1 (ru) * | 2000-10-24 | 2001-12-27 | Московский научно-исследовательский институт медицинской экологии (МНИИМЭ) | Производные хинолина для коррекции системы гемостаза, фармацевтическая композиция, средство для коррекции гемостаза |
| TWI309644B (enExample) * | 2001-02-14 | 2009-05-11 | Nissan Chemical Ind Ltd | |
| US6867320B2 (en) | 2002-02-21 | 2005-03-15 | Asahi Kasei Pharma Corporation | Substituted phenylalkanoic acid derivatives and use thereof |
| JP2007516258A (ja) | 2003-12-12 | 2007-06-21 | ワイス | 心臓血管の疾患治療に有用なキノリン誘導体 |
| BRPI0518222A (pt) * | 2004-10-19 | 2008-11-04 | Hoffmann La Roche | composto, processo para a sua manufatura, composições farmacêuticas que os compreendem, método para o tratamento e/ou prevenção de enfermidades que estão associadas com a modulação de receptores de h3 e utilização dos mesmos |
| CN101611029B (zh) * | 2006-12-21 | 2014-09-10 | 辉瑞产品公司 | 2-((4-(1-甲基-4-(吡啶-4-基)-1h-吡唑-3-基)苯氧基)甲基)喹啉的琥珀酸盐 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3814504A1 (de) * | 1988-04-29 | 1989-11-09 | Bayer Ag | (alpha)-substituierte 4-(chinolin-2-yl-methoxy)phenylessigsaeuren und -ester, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
| DE3900261A1 (de) * | 1988-05-31 | 1989-12-07 | Bayer Ag | Substituierte 4-(chinolin-2-yl-methoxy) phenyl-essigsaeure-derivate |
| DE3908298A1 (de) * | 1989-03-14 | 1990-09-20 | Bayer Ag | Substituierte (chinolin-2-yl-methoxy)phenyl-n,n'-sulfonylharnstoffe, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
| DE3916663A1 (de) * | 1989-05-23 | 1990-11-29 | Bayer Ag | Substituierte (chinolin-2-yl-methoxy)phenyl-acyl-sulfonamide und -cyanamide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
| DE3927930A1 (de) * | 1989-08-24 | 1991-02-28 | Bayer Ag | Cyclisch substituierte (chinolin-2-yl-methoxy)phenyl-essig-saeure-derivate |
| DE3927931A1 (de) * | 1989-08-24 | 1991-02-28 | Bayer Ag | Disubstituierte (chinolin-2-yl-methoxy)phenylessigsaeure-derivate |
-
1991
- 1991-02-22 DE DE4105551A patent/DE4105551A1/de not_active Withdrawn
-
1992
- 1992-01-29 AU AU10542/92A patent/AU641585B2/en not_active Ceased
- 1992-02-10 EP EP92102156A patent/EP0499926B1/de not_active Expired - Lifetime
- 1992-02-10 DE DE59207074T patent/DE59207074D1/de not_active Expired - Fee Related
- 1992-02-10 DK DK92102156.4T patent/DK0499926T3/da active
- 1992-02-10 AT AT92102156T patent/ATE142623T1/de not_active IP Right Cessation
- 1992-02-10 ES ES92102156T patent/ES2091958T3/es not_active Expired - Lifetime
- 1992-02-18 JP JP4069073A patent/JPH0592957A/ja active Pending
- 1992-02-19 IL IL10100992A patent/IL101009A/en not_active IP Right Cessation
- 1992-02-19 PL PL92314698A patent/PL171026B1/pl unknown
- 1992-02-19 PL PL92293534A patent/PL170726B1/pl unknown
- 1992-02-19 TW TW081101198A patent/TW200463B/zh active
- 1992-02-19 NZ NZ241654A patent/NZ241654A/en unknown
- 1992-02-20 FI FI920732A patent/FI920732L/fi not_active Application Discontinuation
- 1992-02-20 MY MYPI92000276A patent/MY108459A/en unknown
- 1992-02-21 RU SU925010907A patent/RU2077532C1/ru active
- 1992-02-21 KR KR1019920002638A patent/KR920016424A/ko not_active Ceased
- 1992-02-21 CZ CS92514A patent/CZ282723B6/cs unknown
- 1992-02-21 ZA ZA921268A patent/ZA921268B/xx unknown
- 1992-02-21 IE IE920557A patent/IE75728B1/en not_active IP Right Cessation
- 1992-02-21 HU HU9200582A patent/HUT67037A/hu unknown
-
1996
- 1996-09-12 GR GR960402365T patent/GR3021014T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2077532C1 (ru) | 1997-04-20 |
| AU1054292A (en) | 1992-08-27 |
| DE4105551A1 (de) | 1992-08-27 |
| NZ241654A (en) | 1994-11-25 |
| IL101009A0 (en) | 1992-11-15 |
| EP0499926B1 (de) | 1996-09-11 |
| ATE142623T1 (de) | 1996-09-15 |
| MY108459A (en) | 1996-09-30 |
| ES2091958T3 (es) | 1996-11-16 |
| JPH0592957A (ja) | 1993-04-16 |
| IE75728B1 (en) | 1997-09-24 |
| HU9200582D0 (en) | 1992-05-28 |
| FI920732A7 (fi) | 1992-08-23 |
| FI920732L (fi) | 1992-08-23 |
| EP0499926A1 (de) | 1992-08-26 |
| IL101009A (en) | 1996-08-04 |
| PL293534A1 (en) | 1992-10-05 |
| GR3021014T3 (en) | 1996-12-31 |
| CZ282723B6 (cs) | 1997-09-17 |
| DE59207074D1 (de) | 1996-10-17 |
| PL170726B1 (pl) | 1997-01-31 |
| DK0499926T3 (enExample) | 1997-02-10 |
| ZA921268B (en) | 1992-11-25 |
| KR920016424A (ko) | 1992-09-24 |
| IE920557A1 (en) | 1992-08-26 |
| CS51492A3 (en) | 1992-12-16 |
| FI920732A0 (fi) | 1992-02-20 |
| AU641585B2 (en) | 1993-09-23 |
| HUT67037A (en) | 1995-01-30 |
| TW200463B (enExample) | 1993-02-21 |
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