DK0499926T3 - - Google Patents

Info

Publication number
DK0499926T3
DK0499926T3 DK92102156.4T DK92102156T DK0499926T3 DK 0499926 T3 DK0499926 T3 DK 0499926T3 DK 92102156 T DK92102156 T DK 92102156T DK 0499926 T3 DK0499926 T3 DK 0499926T3
Authority
DK
Denmark
Prior art keywords
substituted
reacting
phenyl
quinolines
halomethylquinolines
Prior art date
Application number
DK92102156.4T
Other languages
English (en)
Inventor
Siegfried Dr Raddatz
Romanis Fruchtmann
Christian Dr Kohlsdorfer
Klaus-Helmut Dr Mohrs
Michael Dr Matzke
Armin Dr Hatzelmann
Reiner Pro Mueller-Peddinghaus
Pia Dr Theisen-Popp
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of DK0499926T3 publication Critical patent/DK0499926T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14Radicals substituted by oxygen atoms
DK92102156.4T 1991-02-22 1992-02-10 DK0499926T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4105551A DE4105551A1 (de) 1991-02-22 1991-02-22 2-substituierte chinoline, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln

Publications (1)

Publication Number Publication Date
DK0499926T3 true DK0499926T3 (da) 1997-02-10

Family

ID=6425643

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92102156.4T DK0499926T3 (da) 1991-02-22 1992-02-10

Country Status (20)

Country Link
EP (1) EP0499926B1 (da)
JP (1) JPH0592957A (da)
KR (1) KR920016424A (da)
AT (1) ATE142623T1 (da)
AU (1) AU641585B2 (da)
CZ (1) CZ282723B6 (da)
DE (2) DE4105551A1 (da)
DK (1) DK0499926T3 (da)
ES (1) ES2091958T3 (da)
FI (1) FI920732A (da)
GR (1) GR3021014T3 (da)
HU (1) HUT67037A (da)
IE (1) IE75728B1 (da)
IL (1) IL101009A (da)
MY (1) MY108459A (da)
NZ (1) NZ241654A (da)
PL (2) PL171026B1 (da)
RU (1) RU2077532C1 (da)
TW (1) TW200463B (da)
ZA (1) ZA921268B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4226649A1 (de) * 1992-08-12 1994-02-17 Bayer Ag Neue isobutylsubstituierte Methansulfonyl-chinolylmethoxyphenyl-cycloalkylessigsäureaminole
US5304563A (en) * 1991-02-22 1994-04-19 Bayer Aktiengesellschaft 2-substituted quinolines, and their use in medicaments
DE4112533A1 (de) * 1991-04-17 1992-10-22 Bayer Ag Verfahren zur herstellung von enantiomerenreinen substituierten (chinolin-2-yl-methoxy)phenyl-essigsaeuren
US5391555A (en) * 1991-11-12 1995-02-21 Miles Inc. Methods for treating inflammatory bowel disease with leukotriene synthesis inhibitors
TW232013B (da) * 1992-04-24 1994-10-11 Takeda Pharm Industry Co Ltd
DE4219765A1 (de) * 1992-06-17 1993-12-23 Bayer Ag Substituierte (Benzothiazolyl- und Chinoxalyl-methoxy)phenylessigsäurederivate
DE4301900A1 (de) * 1993-01-25 1994-07-28 Bayer Ag 2-Oxochinolin-1-yl-methylphenylessigsäurederivate
ES2061406B1 (es) * 1993-05-07 1995-06-01 Uriach & Cia Sa J Nuevos derivados de la 2-(quinolina) con actividad farmacologica.
IL109431A (en) * 1993-05-14 2001-01-11 Warner Lambert Co Pharmaceutical compositions containing n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters), for regulating plasma cholesterol concentration, and certain such novel compounds
US5491172A (en) * 1993-05-14 1996-02-13 Warner-Lambert Company N-acyl sulfamic acid esters (or thioesters), N-acyl sulfonamides, and N-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents
EP0634169B1 (en) * 1993-06-29 2000-01-05 Takeda Chemical Industries, Ltd. Quinoline or quinazoline derivatives and their use in the manufacture of a medicament for the treatment of osteoporosis
DE4443891A1 (de) 1994-12-09 1996-06-13 Bayer Ag Heterocyclisch substituierte Oxy-phenyl-(phenyl)glycinolamide
DE4443892A1 (de) * 1994-12-09 1996-06-13 Bayer Ag 4-(Chinolin-2-yl-methoxy)-phenyl-essigsäurederivate
US6867320B2 (en) 2002-02-21 2005-03-15 Asahi Kasei Pharma Corporation Substituted phenylalkanoic acid derivatives and use thereof
BRPI0417543A (pt) 2003-12-12 2007-03-27 Wyeth Corp quinolinas úteis no tratamento de doença cardiovascular

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3814504A1 (de) * 1988-04-29 1989-11-09 Bayer Ag (alpha)-substituierte 4-(chinolin-2-yl-methoxy)phenylessigsaeuren und -ester, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE3900261A1 (de) * 1988-05-31 1989-12-07 Bayer Ag Substituierte 4-(chinolin-2-yl-methoxy) phenyl-essigsaeure-derivate
DE3908298A1 (de) * 1989-03-14 1990-09-20 Bayer Ag Substituierte (chinolin-2-yl-methoxy)phenyl-n,n'-sulfonylharnstoffe, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE3916663A1 (de) * 1989-05-23 1990-11-29 Bayer Ag Substituierte (chinolin-2-yl-methoxy)phenyl-acyl-sulfonamide und -cyanamide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE3927931A1 (de) * 1989-08-24 1991-02-28 Bayer Ag Disubstituierte (chinolin-2-yl-methoxy)phenylessigsaeure-derivate
DE3927930A1 (de) * 1989-08-24 1991-02-28 Bayer Ag Cyclisch substituierte (chinolin-2-yl-methoxy)phenyl-essig-saeure-derivate

Also Published As

Publication number Publication date
DE4105551A1 (de) 1992-08-27
IL101009A (en) 1996-08-04
CZ282723B6 (cs) 1997-09-17
HUT67037A (en) 1995-01-30
RU2077532C1 (ru) 1997-04-20
GR3021014T3 (en) 1996-12-31
AU1054292A (en) 1992-08-27
IL101009A0 (en) 1992-11-15
PL171026B1 (pl) 1997-02-28
JPH0592957A (ja) 1993-04-16
FI920732A0 (fi) 1992-02-20
ATE142623T1 (de) 1996-09-15
IE75728B1 (en) 1997-09-24
IE920557A1 (en) 1992-08-26
ZA921268B (en) 1992-11-25
PL170726B1 (pl) 1997-01-31
DE59207074D1 (de) 1996-10-17
HU9200582D0 (en) 1992-05-28
MY108459A (en) 1996-09-30
NZ241654A (en) 1994-11-25
AU641585B2 (en) 1993-09-23
PL293534A1 (en) 1992-10-05
FI920732A (fi) 1992-08-23
ES2091958T3 (es) 1996-11-16
TW200463B (da) 1993-02-21
CS51492A3 (en) 1992-12-16
EP0499926B1 (de) 1996-09-11
EP0499926A1 (de) 1992-08-26
KR920016424A (ko) 1992-09-24

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